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ARVO Imaging in the Eye Conference Abstract August 2021

Application of laser Doppler holography in the anterior segment to image blood flow and assess the corneal and lens transparency

Leo Puyo; Clementine David; Rana Saad; Sami Saad; Josselin Gautier; Vincent Borderie; Jose-Alain Sahel; Michel Paques; Michael Atlan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(11):7. doi:

ARVO Annual Meeting Abstract June 2021

SPVN06, a Novel Mutation-Independent AAV-based Gene Therapy, Protects Cone Degeneration in a Pig Model of Retinitis Pigmentosa

Jennifer Noel; archana jalligampala; Myriam Marussig; Pierre-Axel VINOT; Melanie MARIE; Melanie Butler; Florence LORGET; Stephane Boissel; Thierry D Leveillard; Jose Alain Sahel; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1189. doi:

ARVO Annual Meeting Abstract June 2021

Predictive model for incomplete and complete retinal pigment epithelium and outer retinal atrophy in non-exudative age related macular degeneration

Sohani Amarasekera; Anindya Samanta; Mahima Jhingan; Supriya Arora; Sumit R Singh; Davide Tucci; Joseph N Martel; Jose Alain Sahel; Thomas R Friberg; Alexander J Anetakis; Denise Gallagher; Andrew W Eller; Carlo Cagini; Marco Lupidi; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):308. doi:

ARVO Annual Meeting Abstract June 2021

A 1-Month Toxicology and Biodistribution NHP Pilot Study Evaluating a Single Subretinal Bilateral Administration of SPVN06 - A Novel AAV-Based Gene Therapy for the Treatment of Rod-Cone Dystrophies Agnostic of the Causative Mutation

Melanie MARIE; Myriam Marussig; Pierre-Axel VINOT; Thomas VIHTELIC; Ryan F. Boyd; Lauren KNUPP; Jennifer LAMOUREUX; Thierry D Leveillard; Jose Alain Sahel; Florence LORGET

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):194. doi:

ARVO Annual Meeting Abstract June 2021

Retinal degeneration in abetalipoproteinemia

Vasily M. SMIRNOV; Fanny Mochel; Saddek Mohand-Said; Camille Andrieu; Christel Condroyer; Jose Alain Sahel; Christina Zeitz; Isabelle Audo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3216. doi:

ARVO Annual Meeting Abstract June 2021

3D visualization of human retina cells’ anatomy using expansion microscopy

Leyna Boucherit; Anna Verschueren; Marie Darche; Serge A Picaud; Jose Alain Sahel; Michel Paques

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3025. doi:

ARVO Annual Meeting Abstract June 2021

Automated choroid layer segmentation based on wide-field SS-OCT images using deep residual encoder-decoder architecture

Kiran Kumar Vupparaboina; Amrish Selvam; Shan Suthaharan; Mohammed Nasar Ibrahim; Soumya Jana; Jose-Alain Sahel; Kunal K Dansingani; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2162. doi:

ARVO Annual Meeting Abstract June 2021

An automated choroid segmentation approach using transfer learning and encoder-decoder networks

Shan Suthaharan; Gunjan Chhablani; Kiran Kumar Vupparaboina; Jose-Alain Sahel; Kunal K. Dansingani; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2158. doi:

ARVO Annual Meeting Abstract June 2021

AAV-mediated Gene Therapy Restores Retinal Function in CRISPR-based Mouse Models of PRPF31 Retinitis Pigmentosa

Zhouhuan Xi; Abhishek Vats; Jose Alain Sahel; Yuanyuan Chen; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2257. doi:

ARVO Annual Meeting Abstract June 2021

A mouse model with specific inactivation of the thioredoxin-like protein encoded by the nucleoredoxin-like1 reveals its role in the prevention of secondary cone death in retinitis pigmentosa

Emmanuelle Clerin; Emanuele Procopio; Stephanie M Hauck; Jose-Alain Sahel; Erika Tatiana Camacho; Thierry D Leveillard

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2256. doi:

ARVO Annual Meeting Abstract June 2021

Evaluation of the efficacy of rAAV2/2- ND4 gene therapy for Leber hereditary optic neuropathy compared with the natural history

Patrick Yu-Wai-Man; Nancy J Newman; Valerio Carelli; Mark Moster; Catherine Vignal-Clermont; Alfredo A Sadun; Chiara La Morgia; Francesco Bandello; Lorena Castillo Campillo; Stephanie Leruez; Dean Cestari; Robert Foroozan; Rustum Karanjia; Laure Blouin; Magali Taiel; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2676. doi:

ARVO Annual Meeting Abstract June 2021

Simultaneous Perception of Prosthetic and Natural Vision in Patients with Geographic Atrophy

Daniel V Palanker; Yannick Le Mer; Ralf Hornig; Guillaume Buc; Saddek Mohand-Said; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3556. doi:

ARVO Annual Meeting Abstract June 2021

Correlations between progression markers in rod-cone dystrophy due to mutations in RHO, PDE6A, or PDE6B .

Daniel C Chung; Pierre-Axel VINOT; Myriam Marussig; Léa Thiébault; Berthe Pom; Camille Andrieu; Christina Zeitz; Thierry D Leveillard; Stephane Boissel; Saddek Mohand-Said; Isabelle Audo; Jose-Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3539. doi:

ARVO Annual Meeting Abstract June 2021

A Novel Agent in Prevention of Acute Radiation Toxicity in the Mouse Retina

Jennifer Adeghate; Renee Fisher; Wen Hou; Katherine Davoli; Michael W Epperly; Mohammed Saiful Huq; Peter Wipf; Jose-Alain Sahel; Joel S Greenberger; Andrew W Eller

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3290. doi:

ARVO Annual Meeting Abstract June 2021

PHENOTYPE-GENOTYPE CORRELATION AND PROGRESSION MODELING APPLIED TO MUTATIONS IN RPGR -RELATED ROD-CONE DYSTROPHY.

Marco Nassisi; Giuseppe De Bartolo; Saddek Mohand-Said; Vasily M. SMIRNOV; Aline Antonio; Christel Condroyer; Jose Alain Sahel; Christina Zeitz; Isabelle Audo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3238. doi:

ARVO Annual Meeting Abstract June 2021

Optogenetic GS030 Therapy in Subjects with Retinitis Pigmentosa: Safety and Tolerability Up to Two Years After Treatment Administration in the Phase 1/2a PIONEER Study

Joseph N Martel; Elise Boulanger-Scemama; Simona Degli Esposti; Francesco Galluppi; Laure Blouin; Magali Taiel; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3236. doi:

Perspective April 2021

Tackling the Challenges of Product Development Through a Collaborative Rare Disease Network: The Foundation Fighting Blindness Consortium

PDF

Todd A. Durham; Jacque L. Duncan; Allison R. Ayala; David G. Birch; Janet K. Cheetham; Frederick L. Ferris, III; Carel B. Hoyng; Mark E. Pennesi; José-Alain Sahel; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: blindness, rare diseases
Trans. Vis. Sci. Tech.. 2021; 10(4):23. doi: https://doi.org/10.1167/tvst.10.4.23

Visual Neuroscience March 2021

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

PDF

Juliette Varin; Nassima Bouzidi; Miguel Miranda De Sousa Dias; Thomas Pugliese; Christelle Michiels; Camille Robert; Melissa Desrosiers; José-Alain Sahel; Isabelle Audo; Deniz Dalkara; Christina Zeitz
TAGS: biopharmaceutics classification system, dendrites, electroretinography, mice, night blindness, congenital stationary, proteins, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):24. doi: https://doi.org/10.1167/iovs.62.3.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Inherited Retinal Disease (IRD): Online medical education can significantly improve knowledge and confidence for detection in general ophthalmology practice and referral for gene therapy assessment

Siggi Trier; Deborah Middleton; Peter Schoonheim; Jason Comander; Helene Dollfus; Stephen R Russell; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3020. doi:

ARVO Annual Meeting Abstract June 2020

Natural history of retinitis pigmentosa due to RHO , PDE6A OR PDE6B mutations

Myriam Marussig; Léa Thiebault; Pierre-Axel Vinot; Berthe Pom; Camille Andrieu; Christina Zeitz; Thierry D Leveillard; Florence Allouche; Saddek Mohand-Said; Isabelle S Audo; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3035. doi:

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Application of laser Doppler holography in the anterior segment to image blood flow and assess the corneal and lens transparency

SPVN06, a Novel Mutation-Independent AAV-based Gene Therapy, Protects Cone Degeneration in a Pig Model of Retinitis Pigmentosa

Predictive model for incomplete and complete retinal pigment epithelium and outer retinal atrophy in non-exudative age related macular degeneration

A 1-Month Toxicology and Biodistribution NHP Pilot Study Evaluating a Single Subretinal Bilateral Administration of SPVN06 - A Novel AAV-Based Gene Therapy for the Treatment of Rod-Cone Dystrophies Agnostic of the Causative Mutation

Retinal degeneration in abetalipoproteinemia

3D visualization of human retina cells’ anatomy using expansion microscopy

Automated choroid layer segmentation based on wide-field SS-OCT images using deep residual encoder-decoder architecture

An automated choroid segmentation approach using transfer learning and encoder-decoder networks

AAV-mediated Gene Therapy Restores Retinal Function in CRISPR-based Mouse Models of PRPF31 Retinitis Pigmentosa

A mouse model with specific inactivation of the thioredoxin-like protein encoded by the nucleoredoxin-like1 reveals its role in the prevention of secondary cone death in retinitis pigmentosa

Evaluation of the efficacy of rAAV2/2- ND4 gene therapy for Leber hereditary optic neuropathy compared with the natural history

Simultaneous Perception of Prosthetic and Natural Vision in Patients with Geographic Atrophy

Correlations between progression markers in rod-cone dystrophy due to mutations in RHO, PDE6A, or PDE6B .

A Novel Agent in Prevention of Acute Radiation Toxicity in the Mouse Retina

PHENOTYPE-GENOTYPE CORRELATION AND PROGRESSION MODELING APPLIED TO MUTATIONS IN RPGR -RELATED ROD-CONE DYSTROPHY.

Optogenetic GS030 Therapy in Subjects with Retinitis Pigmentosa: Safety and Tolerability Up to Two Years After Treatment Administration in the Phase 1/2a PIONEER Study

Tackling the Challenges of Product Development Through a Collaborative Rare Disease Network: The Foundation Fighting Blindness Consortium

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

Inherited Retinal Disease (IRD): Online medical education can significantly improve knowledge and confidence for detection in general ophthalmology practice and referral for gene therapy assessment

Natural history of retinitis pigmentosa due to RHO , PDE6A OR PDE6B mutations

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