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ARVO Annual Meeting Abstract June 2024

Systemic anti-ceramide immunotherapy corrects diabetic retinopathy by restoring hematopoietic stem cell function

Tim Florian Dorweiler; Arjun Singh; Sandra O'Reilly; Gary Blanchard; Maria B Grant; Richard Kolesnick; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3836.

ARVO Annual Meeting Abstract June 2023

Inhibition of ceramide rich platforms by anti-ceramide immunotherapy prevents retinal endothelial cell damage and the development of diabetic retinopathy.

Tim F. Dorweiler; Arjun Singh; Richard N Kolesnick; Julia V. Busik

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):941.

ARVO Annual Meeting Abstract June 2023

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Ram Prasad; Jason Floyd; Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Sergio Li Calzi; Dibyendu Chakraborty; Angela Harbour; Aayush Rohella; Irina A Pikuleva; Julia V. Busik; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):938.

ARVO Annual Meeting Abstract June 2023

Extracellular Vesicles in Diabetic Retinopathy

Julia V. Busik

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1944.

ARVO Annual Meeting Abstract June 2023

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Cristiano Vieira; Ram Prasad; Sergio Li Calzi; Irina A Pikuleva; Julia V. Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1834.

ARVO Annual Meeting Abstract June 2023

Calvarium bone marrow is the source of bone marrow-derived cells that migrate into the injured retina

Sergio Li Calzi; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Ram Prasad; Julia V. Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3866.

Retina April 2023

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

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Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sergio Li Calzi; Mariana DuPont; Jason Floyd; Sanford Boye; Vince Chiodo; Julia V. Busik; Maria B. Grant
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, intravitreal injections, mice, retina, blood capillaries, inflammation, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(4):20. https://doi.org/10.1167/tvst.12.4.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Anti-ceramide immunotherapy for diabetic retinopathy

Tim Florian Dorweiler; Peter Nolan; Richard N. Kolesnick; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):459.

ARVO Annual Meeting Abstract June 2022

Correction of diabetic retinopathy by mitochondrial transfer

Denis A Proshlyakov; Sandra S Hammer; Sergio Li Calzi; Tim Florian Dorweiler; Cristiano P. Vieira; Kiera Fisher; Shari Atilano; M.Cristina Kenney; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):791 – F0350.

ARVO Annual Meeting Abstract June 2022

Intermittent fasting prevents cholesterol accumulation, cholesterol crystal formation and the development of diabetic retinopathy.

Sandra S Hammer; Maria B Grant; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):782 – F0341.

ARVO Annual Meeting Abstract June 2022

Intravitreal administration of AAV2-SIRT1 reverses diabetic retinopathy (DR) in a murine model of type 2 diabetes (T2D)

Maria B Grant; Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sandra S Hammer; Sergio Li Calzi; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2310.

ARVO Annual Meeting Abstract June 2022

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Yvonne Adu-Agyeiwaah; Sandra S Hammer; Cristiano P. Vieira; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Ram Prasad; Sergio Li Calzi; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3591 – A0046.

ARVO Annual Meeting Abstract June 2021

Statins and α cyclodextrin treatments prevent cholesterol crystal-induced pathology in human retinal endothelial cells and in db/db mice.

Sandra S Hammer; Delaney McFarland; George Abela; Sergio Li Calzi; Maria B Grant; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2928.

ARVO Annual Meeting Abstract June 2021

Intravitreal AAV2-SIRT1 administration reverses diabetic retinopathy in db/db mice

Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sandra S Hammer; Sergio Li Calzi; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1106.

ARVO Annual Meeting Abstract July 2019

Modulation of Sphingolipid metabolites in Type 2 Diabetic Retinopathy

Koushik Mondal; Todd Lydic; Rajashekhar Gangaraju; Julia V Busik; Nawajes A Mandal

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2681.

ARVO Annual Meeting Abstract July 2019

EFFECT OF SERUM STARVATION ON THE SIRT1-LXR SIGNALING PATHWAY IN RETINAL ENDOTHELIAL CELLS

Maximilian Sandler; Sandra S Hammer; Delaney Marie McFarland; Elahe Crockett-Torabi; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2702.

ARVO Annual Meeting Abstract July 2019

Control of retinal cholesterol levels by fasting-induced activation of SIRT1-LXR pathway in diabetic retinopathy.

Delaney McFarland; Sandra S Hammer; Maria B Grant; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2704.

ARVO Annual Meeting Abstract July 2019

SPHINGOLIPID METABOLISM CONTRIBUTES TO MITOCHONDRIAL DYSFUNCTON INDUCED BY DIABETOGENIC CONDITION IN RETINAL EPITHELIAL CELLS

Kiera Fisher; Yan Levitsky; Sandra S Hammer; Todd Lydic; David Pegouske; Denis Proshlyakov; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2706.

ARVO Annual Meeting Abstract July 2019

Ceramide-Induced Mitochondrial Changes in Retinal Endothelial Cells

Yan Levitsky; Sandra S Hammer; Todd Lydic; David Pegouske; Kiera Fisher; Denis Proshlyakov; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2707.

ARVO Annual Meeting Abstract July 2019

THE ROLE OF THE SIRT1/LXR SIGNALING AXIS IN RETINAL ENDOTHELIAL CELL INFLAMMATION AND METABOLISM.

Sandra S Hammer; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2728.

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Systemic anti-ceramide immunotherapy corrects diabetic retinopathy by restoring hematopoietic stem cell function

Inhibition of ceramide rich platforms by anti-ceramide immunotherapy prevents retinal endothelial cell damage and the development of diabetic retinopathy.

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Extracellular Vesicles in Diabetic Retinopathy

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Calvarium bone marrow is the source of bone marrow-derived cells that migrate into the injured retina

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

Anti-ceramide immunotherapy for diabetic retinopathy

Correction of diabetic retinopathy by mitochondrial transfer

Intermittent fasting prevents cholesterol accumulation, cholesterol crystal formation and the development of diabetic retinopathy.

Intravitreal administration of AAV2-SIRT1 reverses diabetic retinopathy (DR) in a murine model of type 2 diabetes (T2D)

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Statins and α cyclodextrin treatments prevent cholesterol crystal-induced pathology in human retinal endothelial cells and in db/db mice.

Intravitreal AAV2-SIRT1 administration reverses diabetic retinopathy in db/db mice

Modulation of Sphingolipid metabolites in Type 2 Diabetic Retinopathy

EFFECT OF SERUM STARVATION ON THE SIRT1-LXR SIGNALING PATHWAY IN RETINAL ENDOTHELIAL CELLS

Control of retinal cholesterol levels by fasting-induced activation of SIRT1-LXR pathway in diabetic retinopathy.

SPHINGOLIPID METABOLISM CONTRIBUTES TO MITOCHONDRIAL DYSFUNCTON INDUCED BY DIABETOGENIC CONDITION IN RETINAL EPITHELIAL CELLS

Ceramide-Induced Mitochondrial Changes in Retinal Endothelial Cells

THE ROLE OF THE SIRT1/LXR SIGNALING AXIS IN RETINAL ENDOTHELIAL CELL INFLAMMATION AND METABOLISM.

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