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Articles June 2022

Macular Vascular Imaging and Connectivity Analysis Using High-Resolution Optical Coherence Tomography

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Diogo Cabral; Ana C. Fradinho; Telmo Pereira; Meera S. Ramakrishnan; Tommaso Bacci; Dong An; Sandra Tenreiro; Miguel C. Seabra; Chandrakumar Balaratnasingam; K. Bailey Freund
TAGS: blood capillaries, diagnostic imaging, optical coherence tomography, venule, fluid flow, arteriole, superficial veins, parafoveal region, eye
Trans. Vis. Sci. Tech.. 2022; 11(6):2. doi: https://doi.org/10.1167/tvst.11.6.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Andreas Berlin; Diogo Cabral; Ling Chen; Jeffrey D Messinger; Chandrakumar Balaratnasingam; Randev Mendis; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1018 – F0265. doi:

ARVO Annual Meeting Abstract June 2022

Novel Super Resolution Magnetic Resonance Imaging Processing Pipeline for Whole Eye Imaging with Short Scan Times in High Myopic Eyes

Quan V Hoang; Stanley Chang; Raymond Najjar; Dan Milea; Lawrence Yannuzzi; K Bailey Freund; Jack Grinband

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4334 – A0039. doi:

ARVO Annual Meeting Abstract June 2022

Atherosclerotic disease and serum risk factors in phenotypes of age-related macular degeneration (AMD)

Arielle Coughlin; Robert J. Thomson; Joshua Chazaro; Jason Jo; Oscar Otero-Marquez; Gerardo Ledesma-Gil; Yuehong Tong; Zachary R. Teibel; Katy Tai; Harriet Lloyd; Richard B Rosen; Lawrence Yannuzzi; K Bailey Freund; R. Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):316 – F0147. doi:

ARVO Annual Meeting Abstract June 2022

Age-related macular degeneration (AMD), cardiovascular disease and stroke

Robert Thomson; Joshua Chazaro; Oscar Otero-Marquez; Gerardo Ledesma-Gil; Yuehong Tong; Arielle Coughlin; Zachary R. Teibel; Katy Tai; Harriet Lloyd; Richard B Rosen; Lawrence Yannuzzi; K Bailey Freund; R. Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3526. doi:

ARVO Annual Meeting Abstract June 2022

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Charles Dwight Evers III; Ling Chen; Jeffrey D Messinger; Diogo Cabral; Rosa Dolz-Marco; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1021 – F0268. doi:

Retina January 2022

Ultra-Widefield Indocyanine Green Angiography Reveals Patterns of Choroidal Venous Insufficiency Influencing Pachychoroid Disease

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Tommaso Bacci; Daniel J. Oh; Michael Singer; SriniVas Sadda; K. Bailey Freund
TAGS: blood outflow, discharge, body substance, drainage procedure, eye, indocyanine green angiography, venous anastomosis, venous insufficiency, choroid
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):17. doi: https://doi.org/10.1167/iovs.63.1.17

Includes: Supplemental Content

Retina August 2021

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

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Dongfeng Cao; Belinda Leong; Jeffrey D. Messinger; Deepayan Kar; Thomas Ach; Lawrence A. Yannuzzi; K. Bailey Freund; Christine A. Curcio
TAGS: age-related macular degeneration, atrophic condition of skin, atrophy, cell transdifferentiation, diagnostic imaging, donors, eye, immunohistochemistry, optical coherence tomography, phenotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):34. doi: https://doi.org/10.1167/iovs.62.10.34

Includes: Supplemental Content

Retina August 2021

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

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Cameron Pole; Adrian Au; Eduardo Navajas; K. Bailey Freund; Srinivas Sadda; David Sarraf
TAGS: diagnostic imaging, eye, face, fovea centralis, optical coherence tomography, tissue membrane, vitreous detachment
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):5. doi: https://doi.org/10.1167/iovs.62.10.5

ARVO Annual Meeting Abstract June 2021

Histology and clinical lifecycle of acquired vitelliform lesion, a pathway to atrophy in age-related macular degeneration

Max Philipp Brinkmann; Tommaso Bacci; Jeffrey Messinger; Deepayan Kar; Kenneth R Sloan; Ling Chen; Timothy Hamann; Maximilian Wiest; K Bailey Freund; Sandrine Anne Zweifel; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):301. doi:

ARVO Annual Meeting Abstract June 2021

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

Jeffrey D. Messinger; Ling Chen; Andreas Berlin; Deepayan Kar; Tommaso Bacci; Chandrakumar Balaratnasingham; Randev Mendes; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):654. doi:

ARVO Annual Meeting Abstract June 2021

Transdifferentiated retinal pigment epithelium (RPE) visible in vivo, of relevance to cell-based therapies in age-related macular degeneration (AMD)

Christine A Curcio; Dongfeng Cao; Jeffrey Messinger; Daniela Ferrara; K Bailey Freund; Ling Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2540. doi:

Retina November 2020

Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration

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Amol A. Sura; Ling Chen; Jeffrey D. Messinger; Thomas A. Swain; Gerald McGwin, Jr.; K. Bailey Freund; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):19. doi: https://doi.org/10.1167/iovs.61.13.19

Includes: Supplemental Content

Retina August 2020

Three-Dimensional Characterization of the Normal Human Parafoveal Microvasculature Using Structural Criteria and High-Resolution Confocal Microscopy

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Dong An; Paula Yu; K. Bailey Freund; Dao-Yi Yu; Chandrakumar Balaratnasingam
TAGS: arteriole, blood capillaries, donors, microscopy, confocal, microvascular network, parafoveal region, retina circulation, venule, eye, central retinal artery
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):3. doi: https://doi.org/10.1167/iovs.61.10.3

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2020

Quantitative Fundus Autofluorescence Defines Two Pathways to Geographic Atrophy secondary to Age-related Macular Degeneration.

Oscar Otero-Marquez; Wei Wei; Marco Mazzola; K Bailey Freund; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2020; 61(9):PB0026. doi:

Articles July 2020

Recognizing Atrophy and Mixed-Type Neovascularization in Age-Related Macular Degeneration Via Clinicopathologic Correlation

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Ling Chen; Miaoling Li; Jeffrey D. Messinger; Daniela Ferrara; Christine A. Curcio; K. Bailey Freund
TAGS: age-related macular degeneration, atrophy, neovascularization, pathologic, drusen, eye, choroid, atrophic condition of skin, histology
Trans. Vis. Sci. Tech.. 2020; 9(8):8. doi: https://doi.org/10.1167/tvst.9.8.8

Includes: Supplemental Content

Retina June 2020

Volume Rendering of Dense B-Scan Optical Coherence Tomography Angiography to Evaluate the Connectivity of Macular Blood Flow

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Diogo Cabral; Telmo Pereira; Gerardo Ledesma-Gil; Catarina Rodrigues; Florence Coscas; David Sarraf; K. Bailey Freund
TAGS: angiogram, optical coherence tomography, vascular flow, volume rendering, blood capillaries
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):44. doi: https://doi.org/10.1167/iovs.61.6.44

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2020

Correlation of subretinal drusenoid deposits (SDD) and serum risk factors for cardiovascular disease (CVD)

Harriet O Lloyd; Gerardo Ledesma; Raphael Gildengorn; Catherine Ye; Sharmina Alauddin; Katy W Tai; K Bailey Freund; Roland Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1421. doi:

ARVO Annual Meeting Abstract June 2020

Differential Response to Glucocorticoid Immunosuppression of Two Distinct Inflammatory Signs Associated with Punctate Inner Choroidopathy

Aliaa Abdelhakim; Lawrence A. Yannuzzi; K Bailey Freund; Jesse Jeno Jung

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5362. doi:

ARVO Annual Meeting Abstract June 2020

Expanding the Spectrum of Bartonella-Associated Neuroretinitis

Jorge Orellana-Rios; Belinda Leong; Juan I Verdaguer-Diaz; K Bailey Freund

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5369. doi:

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Macular Vascular Imaging and Connectivity Analysis Using High-Resolution Optical Coherence Tomography

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Novel Super Resolution Magnetic Resonance Imaging Processing Pipeline for Whole Eye Imaging with Short Scan Times in High Myopic Eyes

Atherosclerotic disease and serum risk factors in phenotypes of age-related macular degeneration (AMD)

Age-related macular degeneration (AMD), cardiovascular disease and stroke

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Ultra-Widefield Indocyanine Green Angiography Reveals Patterns of Choroidal Venous Insufficiency Influencing Pachychoroid Disease

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

Histology and clinical lifecycle of acquired vitelliform lesion, a pathway to atrophy in age-related macular degeneration

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

Transdifferentiated retinal pigment epithelium (RPE) visible in vivo, of relevance to cell-based therapies in age-related macular degeneration (AMD)

Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration

Three-Dimensional Characterization of the Normal Human Parafoveal Microvasculature Using Structural Criteria and High-Resolution Confocal Microscopy

Quantitative Fundus Autofluorescence Defines Two Pathways to Geographic Atrophy secondary to Age-related Macular Degeneration.

Recognizing Atrophy and Mixed-Type Neovascularization in Age-Related Macular Degeneration Via Clinicopathologic Correlation

Volume Rendering of Dense B-Scan Optical Coherence Tomography Angiography to Evaluate the Connectivity of Macular Blood Flow

Correlation of subretinal drusenoid deposits (SDD) and serum risk factors for cardiovascular disease (CVD)

Differential Response to Glucocorticoid Immunosuppression of Two Distinct Inflammatory Signs Associated with Punctate Inner Choroidopathy

Expanding the Spectrum of Bartonella-Associated Neuroretinitis

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