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ARVO Annual Meeting Abstract June 2024

In vivo and ex vivo characterization of photoreceptor cell replacement therapy using scaffolds in a non-human primate model of vision loss

Soumaya Belhadj; Agustin Luz Madrigal; Laura Patak; Jacqueline Gayet; Hector Baez; Jennifer LaPorta; William Fischer; Nathaniel Foley; Arvydas Maminishkis; Kapil Bharti; Juan Amaral; Vamsi Gullapalli; David Allen Diloreto; Teresa Puthussery; David M Gamm; Juliette E Mcgregor

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3825.

ARVO Annual Meeting Abstract June 2024

Feasibility of a double dose of iPSC-RPE patch transplantation in a laser-induced RPE ablation swine model

Juan Amaral; Irina Bunea; Mandeep Singh; ruchi Fnu; Jair Montford; Francesca Barone; Kristi Creel; Arvydas Maminishkis; Teresa Magone De Cuadros Costa; Amir H Kashani; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):896.

ARVO Annual Meeting Abstract June 2024

Localization of Toll-like Receptors and Intracellular Lipid Droplets in an anaphylatoxin-induced AMD model in iPSC-derived retinal pigment epithelium

Katherine Patterson; Congxiao Zhang; Andrew Fausey; David McGaughey; Joys Annita David; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):739.

ARVO Annual Meeting Abstract June 2024

Interferon regulatory factor 5 (IRF5) gene ablation causes senescencent changes in mouse choroid

Congxiao Zhang; Russell Quinn; Joys Annita David; Katherine Patterson; Eric Nguyen; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):732.

ARVO Annual Meeting Abstract June 2024

Classifying Mouse RPE Morphometric Heterogeneity Using REShAPE – an AI-based Image Analysis Tool

Dylan Walmsley; Dominik Reichert; Huirong Li; Kapil Bharti; ruchi Fnu; Davide Ortolan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):363.

ARVO Annual Meeting Abstract June 2024

USE OF METFORMIN AS A POTENTIAL TREATMENT FOR STARGARDT MACULOPATHY

Devika Abhijit Bose; Mitra Farnoodian; Ruchi Sharma; David McGaughey; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2203.

ARVO Annual Meeting Abstract June 2024

Deciphering Shared Phenotypic Traits in iPSC-Derived RPE from Ciliopathy Patients with Mutation-Specific Variations

Dominik Reichert; Davide Ortolan; Jair Montford; Jiwon Ryu; Colby F. Lewallen; Devika Bose; Keren Melendez; Laryssa Huryn; Wadih M Zein; Brian Patrick Brooks; Helen Louise May-Simera; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3821.

ARVO Annual Meeting Abstract June 2024

A Biologically Validated, Non-Invasive Method to Quantify the Membrane-Specific Responses of RPE Cells Using Electrochemical Impedance Spectroscopy

Colby F. Lewallen; Arvydas Maminishkis; Qin Wan; Dominik Reichert; Jair Montford; ruchi Fnu; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3145.

ARVO Annual Meeting Abstract June 2024

Macrophages induce choroidal senescence in an in vitro model of 3D RPE/choroid to cause neovascular AMD-like phenotypes

Tea Soon Park; Russell Quinn; Congxiao Zhang; Eric Nguyen; Casey Cargill; Devika Abhijit Bose; Min Jae Song; Marc Ferrer; ruchi Fnu; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4962.

ARVO Annual Meeting Abstract June 2024

Comparison of older and younger fibroblast in the homeostasis of 3D bioprinted oBRB model

Casey Cargill; Eric Nguyen; Amir Ali; Tea Soon Park; Rishabh Hirday; russell quinn; Colby F. Lewallen; Mitra Farnoodian; Congxiao Zhang; Davide Ortolan; Devika Abhijit Bose; Jair Montford; Omar Memon; Arvydas Maminishkis; ruchi Fnu; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4526.

ARVO Annual Meeting Abstract June 2024

Analysis of Primary Cilia Phenotypes in Patient-Derived iPSC-RPE

Keren Melendez; Dominik Reichert; Colby F. Lewallen; Davide Ortolan; Jair Montford; Jiwon Ryu; Devika Abhijit Bose; Wadih M Zein; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4523.

ARVO Annual Meeting Abstract June 2024

3D organelle map of polarized iPSC-RPE using high-content imaging and volumetric segmentation

Davide Ortolan; Pushkar Sathe; Andrei Volkov; Dominik Reichert; Sheldon Sebastian; Nicholas Schaub; Gianluca Pegoraro; Arvydas Maminishkis; Ruchi Sharma; Peter Bajcsy; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4515.

ARVO Annual Meeting Abstract June 2024

Investigating the Retinotoxic Effects of Hydroxychloroquine: An In Vitro iPSC-RPE Model to Probe Genetics, Mechanism, and Develop Potential Therapies

Helena Herzog; Jair Montford; Devika Bose; Kapil Bharti; Ruchi Sharma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4512.

ARVO Annual Meeting Abstract June 2024

Investigating Genome Editing As A Therapeutic For Late-Onset Retinal Degeneration

Ana Alonso-Carriazo Fernandez; Zaynab Butt; Gavin Arno; Mariya Moosajee; Kapil Bharti; Amanda-Jayne Francis Carr

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4270.

ARVO Annual Meeting Abstract June 2024

A new challenging approach for testing RPE cell therapies

Elena Daniele; Jair Montford; Arvydas Maminishkis; ruchi Fnu; Kapil Bharti; Stefano Ferrari; Diego Ponzin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5381.

Methods March 2024

An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model

PDF

Francesca Barone; Irina Bunea; Kristi Creel; Ruchi Sharma; Juan Amaral; Arvydas Maminishkis; Kapil Bharti
TAGS: animal model, suidae, training, vision, visual psychophysics
Trans. Vis. Sci. Tech.. 2024; 13(3):8. https://doi.org/10.1167/tvst.13.3.8

Includes: Multimedia, Supplemental Content

Optica Fall Vision Meeting Abstract December 2023

Invited Session II: Retinal remodeling and regeneration: Developing autologous iPSC-RPE therapy for the treatment of AMD patients

Ruchi Sharma; Kapil Bharti
TAGS: induced pluripotent stem cells
Journal of Vision. 2023; 23(15):9. https://doi.org/10.1167/jov.23.15.9

ARVO Annual Meeting Abstract June 2023

Metformin Attenuates the Hallmarks of Stargardt Disease

Mitra Farnoodian; Francesca Barone; Marisa Boyle; Rishabh Gupta; Luke Matthew Nelson; Devika Abhijit Bose; Bokkyoo Jun; William C Gordon; Khanh V Do; Marie-Audrey Kautzmann Guerin; Tiziana Cogliati; Peter Walter; Laryssa Huryn; Nicolas G Bazan; Brian Patrick Brooks; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):476.

ARVO Annual Meeting Abstract June 2023

A PHASE I/IIA TRIAL TO TEST SAFETY AND FEASIBILITY OF AN AUTOLOGOUS IPS CELL-DERIVED RETINAL PIGMENT EPITHELIUM PATCH IN AGE-RELATED MACULAR DEGENERATION PATIENTS

Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):924.

ARVO Annual Meeting Abstract June 2023

TYROSINASE Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects

Arnold Leigh; Aman George; Tyler Pfister; Charles DeYoung; Ruchi Sharma; Mones Abu-Asab; Jizhong Zou; Kapil Bharti; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):775.

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In vivo and ex vivo characterization of photoreceptor cell replacement therapy using scaffolds in a non-human primate model of vision loss

Feasibility of a double dose of iPSC-RPE patch transplantation in a laser-induced RPE ablation swine model

Localization of Toll-like Receptors and Intracellular Lipid Droplets in an anaphylatoxin-induced AMD model in iPSC-derived retinal pigment epithelium

Interferon regulatory factor 5 (IRF5) gene ablation causes senescencent changes in mouse choroid

Classifying Mouse RPE Morphometric Heterogeneity Using REShAPE – an AI-based Image Analysis Tool

USE OF METFORMIN AS A POTENTIAL TREATMENT FOR STARGARDT MACULOPATHY

Deciphering Shared Phenotypic Traits in iPSC-Derived RPE from Ciliopathy Patients with Mutation-Specific Variations

A Biologically Validated, Non-Invasive Method to Quantify the Membrane-Specific Responses of RPE Cells Using Electrochemical Impedance Spectroscopy

Macrophages induce choroidal senescence in an in vitro model of 3D RPE/choroid to cause neovascular AMD-like phenotypes

Comparison of older and younger fibroblast in the homeostasis of 3D bioprinted oBRB model

Analysis of Primary Cilia Phenotypes in Patient-Derived iPSC-RPE

3D organelle map of polarized iPSC-RPE using high-content imaging and volumetric segmentation

Investigating the Retinotoxic Effects of Hydroxychloroquine: An In Vitro iPSC-RPE Model to Probe Genetics, Mechanism, and Develop Potential Therapies

Investigating Genome Editing As A Therapeutic For Late-Onset Retinal Degeneration

A new challenging approach for testing RPE cell therapies

An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model

Invited Session II: Retinal remodeling and regeneration: Developing autologous iPSC-RPE therapy for the treatment of AMD patients

Metformin Attenuates the Hallmarks of Stargardt Disease

A PHASE I/IIA TRIAL TO TEST SAFETY AND FEASIBILITY OF AN AUTOLOGOUS IPS CELL-DERIVED RETINAL PIGMENT EPITHELIUM PATCH IN AGE-RELATED MACULAR DEGENERATION PATIENTS

TYROSINASE Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects

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