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Retina April 2025

Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

PDF

Lukas Goerdt; Mark E. Clark; Tracy N. Thomas; Liyan Gao; Gerald McGwin, Jr.; Martin Hammer; Jason N. Crosson; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, diagnostic imaging, eye, fluorescence, ophthalmoscopy, vision, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):56. https://doi.org/10.1167/iovs.66.4.56

Includes: Supplemental Content

Retina March 2025

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

PDF

Lukas Goerdt; Andreas Berlin; Liyan Gao; Thomas A. Swain; Sarah S. Kim; Gerald McGwin; Mark E. Clark; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: aging, autofluorescence, eye, lutein, pigment, maps, meridians, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):61. https://doi.org/10.1167/iovs.66.3.61

Includes: Supplemental Content

Retina January 2025

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

PDF

Christine A. Curcio; Jeffrey D. Messinger; Andreas Berlin; Kenneth R. Sloan; D. Scott McLeod; Malia M. Edwards; Jacques Bijon; K. Bailey Freund
TAGS: age-related macular degeneration, age-related macular degeneration, nonexudative, atrophic condition of skin, atrophy, autofluorescence, drusen, fundus autofluorescence imaging, histology, pathology, clinical, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):49. https://doi.org/10.1167/iovs.66.1.49

Includes: Multimedia, Supplemental Content

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

PDF

Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Retina August 2024

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

PDF

Lukas Goerdt; Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio; Deepayan Kar
TAGS: digestive tract decontamination, rod photoreceptors, vision, eye, aging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):25. https://doi.org/10.1167/iovs.65.10.25

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2024

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

PDF

Deepayan Kar; Mohymina Amjad; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Kenneth R. Sloan; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, aging, fovea centralis, vision, impairment, rod photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):40. https://doi.org/10.1167/iovs.65.8.40

ARVO Annual Meeting Abstract June 2024

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Cynthia Owsley; Gerald McGwin; Thomas A. Swain; Mark E Clark; Tracy N Thomas; Lucas Goerdt; Kenneth R Sloan; Emily Trittschuh; Yu Jiang; Julia Owen; Cecilia S Lee; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2267.

ARVO Annual Meeting Abstract June 2024

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Yu Jiang; Thomas A. Swain; Christine Mac Donald; Ariel Rokem; Julia P Owen; Gerald McGwin; Christine A Curcio; Kenneth R Sloan; Emily H Trittschuh; Swati Rane Levendovszky; Mark E Clark; Cynthia Owsley; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):446.

ARVO Annual Meeting Abstract June 2024

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio; Deepayan Kar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2295.

ARVO Annual Meeting Abstract June 2024

Spatial profiling of Macular Pigment in Multiple Sclerosis

Jamie Mitchell; Stephanie Gemma McIlwaine; Kenneth R Sloan; Tunde Peto; Ruth E Hogg; Imre Lengyel; Lajos Csincsik

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6638.

Retina May 2024

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

PDF

Cynthia Owsley; Gerald McGwin, Jr.; Thomas A. Swain; Mark E. Clark; Tracy N. Thomas; Lukas Goerdt; Kenneth R. Sloan; Emily H. Trittschuh; Yu Jiang; Julia P. Owen; Cecilia S. Lee; Christine A. Curcio
TAGS: age-related macular degeneration, aging, cognition, cognitive ability, mental processes, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):16. https://doi.org/10.1167/iovs.65.5.16

Retina April 2024

Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years

PDF

Marlene Saßmannshausen; Senem Döngelci; Marc Vaisband; Leon von der Emde; Kenneth R. Sloan; Jan Hasenauer; Frank G. Holz; Steffen Schmitz-Valckenberg; Thomas Ach
TAGS: age-related macular degeneration, biological markers
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):45. https://doi.org/10.1167/iovs.65.4.45

Includes: Supplemental Content

Review March 2024

Age-Related Macular Degeneration, a Mathematically Tractable Disease

PDF

Christine A. Curcio; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Thomas Ach
TAGS: age-related macular degeneration, aging, drusen, eye, fovea centralis, lutein, macula lutea, photoreceptors, retina, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):4. https://doi.org/10.1167/iovs.65.3.4

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging December 2023

Volumetric Reconstruction of a Human Retinal Pigment Epithelial Cell Reveals Specialized Membranes and Polarized Distribution of Organelles

PDF

Maximilian Lindell; Deepayan Kar; Aleksandra Sedova; Yeon Jin Kim; Orin S. Packer; Ursula Schmidt-Erfurth; Kenneth R. Sloan; Mike Marsh; Dennis M. Dacey; Christine A. Curcio; Andreas Pollreisz
TAGS: organelles, reconstructive surgical procedures, retinal pigment cell, tissue membrane, mitochondria, photoreceptors, cell body, diagnostic imaging, volume, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):35. https://doi.org/10.1167/iovs.64.15.35

Retina July 2023

Quantitative Fundus Autofluorescence in Systemic Chloroquine/Hydroxychloroquine Therapy: One Year Follow-Up

PDF

Victoria Radun; Andreas Berlin; Ioana-Sandra Tarau; Nikolai Kleefeldt; Clara Reichel; Jost Hillenkamp; Frank G. Holz; Kenneth R. Sloan; Marlene Saßmannshausen; Thomas Ach
TAGS: chloroquine, follow-up, fundus autofluorescence imaging, hydroxychloroquine, longitudinal studies
Trans. Vis. Sci. Tech.. 2023; 12(7):8. https://doi.org/10.1167/tvst.12.7.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Retest variability of quantitative fundus autofluorescence and its determinants in age-related macular degeneration: A MACUSTAR study report

Leon Alexander von der Emde; Merten Mallwitz; Steffen Schmitz-Valckenberg; Marlene Sassmannshausen; Kenneth R Sloan; Marc Vaisband; Jan Henrik Terheyden; Robert Patrick Finger; Frank G Holz; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1057.

ARVO Annual Meeting Abstract June 2023

Personalized lens correction for quantitative fundus autofluorescence measurements

Thomas Ach; Geena Rennen; Raffael G. Liegl; Kenneth R Sloan; Frank G Holz; Leon Alexander von der Emde

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2382.

ARVO Annual Meeting Abstract June 2023

Correlation of structural biomarkers to fundus-controlled perimetry in intermediate age-related macular degeneration: a seven-year longitudinal study

Marlene Sassmannshausen; Senem Döngelci; Marc Vaisband; Leon Alexander von der Emde; Kenneth R Sloan; Jan Hasenauer; Frank G Holz; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2766.

ARVO Annual Meeting Abstract June 2023

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Cynthia Owsley; Jason Neal Crosson; Kenneth R Sloan; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5005.

ARVO Annual Meeting Abstract June 2023

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

Kenneth R Sloan; Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Jason Neal Crosson; Cynthia Owsley; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5021.

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Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Spatial profiling of Macular Pigment in Multiple Sclerosis

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years

Age-Related Macular Degeneration, a Mathematically Tractable Disease

Volumetric Reconstruction of a Human Retinal Pigment Epithelial Cell Reveals Specialized Membranes and Polarized Distribution of Organelles

Quantitative Fundus Autofluorescence in Systemic Chloroquine/Hydroxychloroquine Therapy: One Year Follow-Up

Retest variability of quantitative fundus autofluorescence and its determinants in age-related macular degeneration: A MACUSTAR study report

Personalized lens correction for quantitative fundus autofluorescence measurements

Correlation of structural biomarkers to fundus-controlled perimetry in intermediate age-related macular degeneration: a seven-year longitudinal study

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

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