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Meeting Abstract (11)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (12)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (11)
Glaucoma (1)
Review (1)

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Cornea (2)
Eye Anatomy and Disorders (2)
Genetics (2)
Biochemistry and Molecular Biology (1)
Clinical and Epidemiologic Research (1)
Glaucoma (1)
Translational Research (1)

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cornea (2)
artificial intelligence (1)
cardiac ct (1)
cohort studies (1)
corneal edema (1)
corneal endothelium (1)
datasets (1)
descemet's membrane endothelial keratoplasty (1)
diagnostic imaging (1)
edema (1)

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Glaucoma July 2025

Decoding the Cornea-Glaucoma Association: Evidence From Mendelian Randomization

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Victor A. de Vries; Anita Szabo; Joëlle E. Vergroesen; Siyin Liu; Karin A. van Garderen; Kirithika Muthusamy; Petra Liskova; Lubica Dudakova; Anthony P. Khawaja; Stephen J. Tuft; Caroline C. W. Klaver; Alice E. Davidson; Wishal D. Ramdas
TAGS: cardiac ct, cohort studies, cornea, glaucoma, mendelian randomization analysis, genetic risk score, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):22. https://doi.org/10.1167/iovs.66.9.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

Characterizing the extracellular landscape of Fuchs endothelial corneal dystrophy

Anne-Marie Shirley Kladny; Nihar Bhattacharyya; Christina Zarouchlioti; Kirithika Muthusamy; Caroline Thaung; Stephen Tuft; Alice Davidson

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1210.

ARVO Annual Meeting Abstract June 2025

Allelic Structure and Somatic Instability Dynamics of CTG18.1 in Fuchs Endothelial Corneal Dystrophy

Siyin Liu; Marc Ciosi; Amanda Nicole Sadan; Christina Zarouchlioti; Anita Szabo; Nikolas Pontikos; Kirithika Muthusamy; Petra Liskova; Stephen Tuft; Darren Monckton; Alice Davidson

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1204.

ARVO Annual Meeting Abstract June 2025

Implementing a gene burden approach in a genetically refined Fuchs’ endothelial corneal dystrophy patient cohort identifies rare microRNA variants as a novel genetic cause of disease.

Marcos Costa; Amanda Nicole Sadan; Nihar Bhattacharyya; Niuzheng Chai; Christina Zarouchlioti; Siyin Liu; Anita Szabo; Kirithika Muthusamy; Ismail Moghul; Nikolas Pontikos; Petra Liskova; Stephen Tuft; Alice Davidson

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1830.

Review June 2025

Current Applications of Artificial Intelligence for Fuchs Endothelial Corneal Dystrophy: A Systematic Review

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Siyin Liu; Lynn Kandakji; Aleksander Stupnicki; Dayyanah Sumodhee; Marcello T. Leucci; Scott Hau; Shafi Balal; Arthur Okonkwo; Ismail Moghul; Sandor P. Kanda; Bruce D. Allan; Dan M. Gore; Kirithika Muthusamy; Alison J. Hardcastle; Alice E. Davidson; Petra Liskova; Nikolas Pontikos
TAGS: artificial intelligence, cornea, corneal edema, corneal endothelium, datasets, diagnostic imaging, endothelium, eye, hereditary corneal dystrophy, systematic reviews
Trans. Vis. Sci. Tech.. 2025; 14(6):12. https://doi.org/10.1167/tvst.14.6.12

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Spatial transcriptomics reveal isoform-specific patterns of TCF4 dysregulation in CTG18.1 expansion positive FECD case-derived corneal endothelial cells

Nihar Bhattacharyya; Christina Zarouchlioti; Jana Jedlickova; Lubica Dudakova; Pavlina Skalicka; Kirithika Muthusamy; Petra Liskova; Alison J Hardcastle; Stephen Tuft; Alice Davidson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):644.

ARVO Annual Meeting Abstract June 2024

Novel insights into Fuchs endothelial corneal dystrophy through genetic, demographic, and phenotypic correlations

Siyin Liu; Amanda Sadan; Anita Szabo; Nihar Bhattacharyya; Christina Zarouchlioti; Marcos Abreu Costa; Lubica Dudakova; Marc Ciosi; Pavlina Skalicka; Nikolas Pontikos; Catey Bunce; Darren Monckton; Kirithika Muthusamy; Petra Liskova; Stephen Tuft; Alice Davidson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4229.

ARVO Annual Meeting Abstract June 2022

CTG18.1-mediated Fuchs endothelial corneal dystrophy: characterizing biomarkers of pathogenicity in patients with rare intermediate triplet repeat expansions

Nihar Bhattacharyya; Amanda Sadan; Christina Zarouchlioti; Nathaniel Jordan Hafford-Tear; Kirithika Muthusamy; Alison J Hardcastle; Pavlina Skalicka; Petra Liskova; Stephen Tuft; Alice E Davidson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1588 – A0377.

ARVO Annual Meeting Abstract June 2021

CTG18.1-mediated Fuchs Endothelial Corneal Dystrophy: defining unique signatures of transcriptomic dysregulation

Nihar Bhattacharyya; Nathaniel Hafford-Tear; Amanda N Sadan; Christina Zarouchlioti; Kirithika Muthusamy; Petra Liskova; Stephen J Tuft; Alison J Hardcastle; Alice E Davidson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1454.

ARVO Annual Meeting Abstract July 2019

Development of patient-derived iPSC disease models of TGFBI corneal dystrophies

Beatriz Sanchez; Alice E Davidson; Kirithika Muthusamy; Stephen J Tuft; Alison J Hardcastle

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4151.

ARVO Annual Meeting Abstract July 2018

Relationship of severity of Fuchs endothelial corneal dystrophy with triplet repeat expansion in TCF4 and The Potential Implications to Surgical Intervention

Kirithika Muthusamy; Beatriz Sanchez-Pintado; Nathaniel Hafford Tear; Petra Liskova; Peter S Adamson; Alison J Hardcastle; Alice E Davidson; Stephen J. Tuft

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2920.

ARVO Annual Meeting Abstract July 2018

RNA toxicity induced by TCF4 CTG expansions is ameliorated by antisense therapeutics in a patient-derived cell model of Fuchs corneal endothelial dystrophy (FECD).

Alice E Davidson; Christina Zarouchlioti; Beatriz Sanchez-Pintado; Nathaniel Hafford Tear; Pontus Klein; Petra Liskova; Kalyan Dulla; Kirithika Muthusamy; Lubica Dudakova; Pavlina Skalicka; Pirro G Hysi; Michael E. Cheetham; Stephen J. Tuft; Peter S Adamson; Alison J Hardcastle

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3022.

ARVO Annual Meeting Abstract June 2013

Comparison short term post operative hypotony rates of 23 gauge versus 25 gauge needle size in the formation of a cornea-scleral track for Baerveldt tube insertion into the anterior chamber

Kirithika Muthusamy; Jason Cheng; Keith Barton; K Sheng Lim; Laura Beltran-Agullo

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4789.

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