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ARVO Annual Meeting Abstract June 2020

The natural history of choroideremia; progressive loss of visual function and retinal structure

David G Birch; Paul S Bernstein; Ian M MacDonald; Timothy Stout; David S Liao; Kirsten G Locke; Yi Zhai; Audra K Miller; Jenny Holt; Adia Jackson Leung; Somayeh Honarmand; Paul Jordan; Ulrich F O Luhmann; David H Kirn; Peter J Francis

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1908.

Special Issue March 2020

Application of a Deep Machine Learning Model for Automatic Measurement of EZ Width in SD-OCT Images of RP

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Yi-Zhong Wang; Daniel Galles; Martin Klein; Kirsten G. Locke; David G. Birch
TAGS: datasets, machine learning, pixel, spectral domain-optical coherence tomography, training, learning
Trans. Vis. Sci. Tech.. 2020; 9(2):15. https://doi.org/10.1167/tvst.9.2.15

ARVO Annual Meeting Abstract July 2019

A Deep Convolutional Neural Network (CNN) Model for Automatic Measurement of Ellipsoid Zone (EZ) Width in Retinitis Pigmentosa (RP)

Yi-Zhong Wang; Daniel Galles; Martin Klein; Kirsten G Locke; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1527.

ARVO Annual Meeting Abstract July 2019

Annual change in ellipsoid zone (EZ) length in patients with choroideremia

David G Birch; Kirsten G Locke; Yuhui Qui; Jenny Holt; David Kim; Peter Francis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4476.

Visual Psychophysics and Physiological Optics March 2019

Regional Variations and Intra-/Intersession Repeatability for Scotopic Sensitivity in Normal Controls and Patients With Inherited Retinal Degenerations

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Lea D. Bennett; Georgiana Metz; Martin Klein; Kirsten G. Locke; Areeba Khwaja; David G. Birch
TAGS: perimetry, retinal degeneration, nose, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1122-1131. https://doi.org/10.1167/iovs.18-25473

ARVO Annual Meeting Abstract July 2018

Relationships among Spectral Domain Optical Coherence Tomography (SD-OCT) Parameters and Semi-automated Kinetic Perimetry (SKP) Parameters in Subjects with Autosomal Dominant Retinitis Pigmentosa (adRP)

Kirsten G Locke; Donald C Hood; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):28.

Articles August 2017

Dark-Adapted Chromatic Perimetry for Measuring Rod Visual Fields in Patients with Retinitis Pigmentosa

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Lea D. Bennett; Martin Klein; Kirsten G. Locke; Kelly Kiser; David G. Birch
TAGS: perimetry, retinitis pigmentosa, rod photoreceptors, visual fields
Trans. Vis. Sci. Tech.. 2017; 6(4):15. https://doi.org/10.1167/tvst.6.4.15

ARVO Annual Meeting Abstract June 2017

Progressive Loss of Rod Sensitivity in Patients with Autosomal Dominant Retinitis Pigmentosa (adRP) due to RHO Pro23His Mutation

Kirsten G Locke; Sarah Duwel; Artur V Cideciyan; David B. McGuigan; Alessandro Iannaccone; John Heckenlively; Samuel G Jacobson; Michael McCaleb; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3259.

ARVO Annual Meeting Abstract September 2016

Inner Retinal Thickness in Late Stage Retinitis Pigmentosa

Kirsten G Locke; Kelly I Locke-Reddin; Donald Charles Hood; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):143.

ARVO Annual Meeting Abstract September 2016

A tandem duplication of PRDM13 in a family with North Carolina Macular Dystrophy (MCRD1)

Lori S Sullivan; Sara J Bowne; Daniel C. Koboldt; Robert S Fulton; Kirsten G Locke; Kaylie D Webb-Jones; Dianna K H Wheaton; Richard K Wilson; David G Birch; Stephen P Daiger

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3132.

Articles May 2016

Reliability of a Manual Procedure for Marking the EZ Endpoint Location in Patients with Retinitis Pigmentosa

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Rithambara Ramachandran; Cindy X. Cai; Dongwon Lee; Benjamin C. Epstein; Kirsten G. Locke; David G. Birch; Donald C. Hood
TAGS: reliability, retinitis pigmentosa, training, electrophysiological studies
Trans. Vis. Sci. Tech.. 2016; 5(3):6. https://doi.org/10.1167/tvst.5.3.6

Includes: Supplemental Content

Clinical Trials October 2015

Docosahexaenoic Acid Slows Visual Field Progression in X-Linked Retinitis Pigmentosa: Ancillary Outcomes of the DHAX Trial

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Dennis R. Hoffman; Dianna K. Hughbanks-Wheaton; Rand Spencer; Gary E. Fish; N. Shirlene Pearson; Yi-Zhong Wang; Martin Klein; Alison Takacs; Kirsten G. Locke; David G. Birch
TAGS: docosahexaenoic acids, placebos, retinitis pigmentosa, visual fields, x-linked inheritance, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6646-6653. https://doi.org/10.1167/iovs.15-17786

ARVO Annual Meeting Abstract June 2015

Ancillary Outcomes of the DHAX Trial: Docosahexaenoic Acid (DHA) Supplementation in X-Linked Retinitis Pigmentosa (XLRP)

Dennis R Hoffman; Dianna K H Wheaton; Rand Spencer; Gary Fish; N Shirlene Pearson; Yi-Zhong Wang; Martin Klein; Alison Takacs; Kirsten G Locke; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3803.

ARVO Annual Meeting Abstract June 2015

Reliability of a Manual Procedure for Marking the EZ Band Endpoint Location

Rithambara Ramachandran; Cindy Cai; Dongwon Lee; Benjamin Epstein; Kirsten G Locke; David G Birch; Donald Hood

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5280.

Retina November 2014

A Comparison of Progressive Loss of the Ellipsoid Zone (EZ) Band in Autosomal Dominant and X-Linked Retinitis Pigmentosa

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Cindy X. Cai; Kirsten G. Locke; Rithambara Ramachandran; David G. Birch; Donald C. Hood
TAGS: retinitis pigmentosa, x-linked inheritance
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7417-7422. https://doi.org/10.1167/iovs.14-15013

ARVO Annual Meeting Abstract April 2014

A Comparison of Progressive Loss of the Ellipsoid Zone (EZ) in Autosomal Dominant and X-linked Retinitis Pigmentosa

Cindy Xinji Cai; Kirsten G Locke; Rithambara Ramachandran; David G Birch; Donald C Hood

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1396.

ARVO Annual Meeting Abstract April 2014

Annual decline in visual sensitivity at the edge of the OCT-defined ellipsoid zone (EZ) in patients with RPGR-mediated x-linked Retinitis Pigmentosa (xlRP)

David G Birch; Kirsten G Locke; Martin Klein; Dianna K H Wheaton; Dennis R Hoffman; Donald C Hood

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1398.

ARVO Annual Meeting Abstract April 2014

In vivo examination of cone photoreceptors in patients with Retinitis Pigmentosa implanted over five years ago with encapsulated Ciliary Neurotrophic Factor

Iris Miao; Amitabha S Bhakta; Nripun Sredar; Kevin M Ivers; Nimesh Bhikhu Patel; Hope M Queener; Kirsten G Locke; David G Birch; Jason Porter

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2619.

ARVO Annual Meeting Abstract April 2014

High Dose Docosahexaenoic Acid (DHA) Supplementation in X-Linked Retinitis Pigmentosa (XLRP): A 4-Year Randomized, Controlled Clinical Trial

Dennis R Hoffman; Dianna K H Wheaton; Gary E Fish; Rand Spencer; N Shirlene Pearson; Alison Takacs; Martin Klein; Kirsten G Locke; David G Birch

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5010.

Articles December 2013

A Comparison of Methods for Tracking Progression in X-Linked Retinitis Pigmentosa Using Frequency Domain OCT

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Rithambara Ramachandran; Lisa Zhou; Kirsten G. Locke; David G. Birch; Donald C. Hood
TAGS: retinitis pigmentosa, volume, x-linked inheritance
Trans. Vis. Sci. Tech.. 2013; 2(7):5. https://doi.org/10.1167/tvst.2.7.5

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The natural history of choroideremia; progressive loss of visual function and retinal structure

Application of a Deep Machine Learning Model for Automatic Measurement of EZ Width in SD-OCT Images of RP

A Deep Convolutional Neural Network (CNN) Model for Automatic Measurement of Ellipsoid Zone (EZ) Width in Retinitis Pigmentosa (RP)

Annual change in ellipsoid zone (EZ) length in patients with choroideremia

Regional Variations and Intra-/Intersession Repeatability for Scotopic Sensitivity in Normal Controls and Patients With Inherited Retinal Degenerations

Relationships among Spectral Domain Optical Coherence Tomography (SD-OCT) Parameters and Semi-automated Kinetic Perimetry (SKP) Parameters in Subjects with Autosomal Dominant Retinitis Pigmentosa (adRP)

Dark-Adapted Chromatic Perimetry for Measuring Rod Visual Fields in Patients with Retinitis Pigmentosa

Progressive Loss of Rod Sensitivity in Patients with Autosomal Dominant Retinitis Pigmentosa (adRP) due to RHO Pro23His Mutation

Inner Retinal Thickness in Late Stage Retinitis Pigmentosa

A tandem duplication of PRDM13 in a family with North Carolina Macular Dystrophy (MCRD1)

Reliability of a Manual Procedure for Marking the EZ Endpoint Location in Patients with Retinitis Pigmentosa

Docosahexaenoic Acid Slows Visual Field Progression in X-Linked Retinitis Pigmentosa: Ancillary Outcomes of the DHAX Trial

Ancillary Outcomes of the DHAX Trial: Docosahexaenoic Acid (DHA) Supplementation in X-Linked Retinitis Pigmentosa (XLRP)

Reliability of a Manual Procedure for Marking the EZ Band Endpoint Location

A Comparison of Progressive Loss of the Ellipsoid Zone (EZ) Band in Autosomal Dominant and X-Linked Retinitis Pigmentosa

A Comparison of Progressive Loss of the Ellipsoid Zone (EZ) in Autosomal Dominant and X-linked Retinitis Pigmentosa

Annual decline in visual sensitivity at the edge of the OCT-defined ellipsoid zone (EZ) in patients with RPGR-mediated x-linked Retinitis Pigmentosa (xlRP)

In vivo examination of cone photoreceptors in patients with Retinitis Pigmentosa implanted over five years ago with encapsulated Ciliary Neurotrophic Factor

High Dose Docosahexaenoic Acid (DHA) Supplementation in X-Linked Retinitis Pigmentosa (XLRP): A 4-Year Randomized, Controlled Clinical Trial

A Comparison of Methods for Tracking Progression in X-Linked Retinitis Pigmentosa Using Frequency Domain OCT

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