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Articles January 2022

Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery

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Li-Fong Seet; Zhu Li Yap; Stephanie W. L. Chu; Li Zhen Toh; Farah Ilyana Ibrahim; Xiao Teng; Tina T. Wong
TAGS: combined modality therapy, fibrosis, glaucoma surgery, mitomycin, oryctolagus cuniculus, postoperative care, surgical procedures, minimally invasive, valproic acid, blister, collagen
Trans. Vis. Sci. Tech.. 2022; 11(1):30. doi: https://doi.org/10.1167/tvst.11.1.30

Glaucoma February 2021

Altered Iris Aquaporin Expression and Aqueous Humor Osmolality in Glaucoma

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Olivia S. Huang; Li-Fong Seet; Henrietta W. Ho; Stephanie W. Chu; Arun Narayanaswamy; Shamira A. Perera; Rahat Husain; Tin Aung; Tina T. Wong
TAGS: aqueous humor, glaucoma, iris, osmolality, water channels, aquaporin 1, eye, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):34. doi: https://doi.org/10.1167/iovs.62.2.34

ARVO Annual Meeting Abstract July 2018

Upregulation of RelB in the Post-Operative Conjunctiva and its Role in Regulating Inflammation

Li-Fong Seet; Li Zhen Toh; Stephanie Chu; Tina Wong

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):121. doi:

ARVO Annual Meeting Abstract July 2018

Valproic Acid Reduces Inflammation following Experimental Glaucoma Surgery

Tina Wong; Li Zhen Toh; Stephanie Chu; Li Fong Seet

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):477. doi:

Biochemistry and Molecular Biology March 2018

Bevacizumab Promotes T-Cell–Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring

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Li-Fong Seet; Li Zhen Toh; Stephanie Chu; Sharon N. Finger; Florent Ginhoux; Wanjin Hong; Tina T. Wong
TAGS: bevacizumab, cicatrix, conjunctiva, mice, t-lymphocytes, collagen, blister, vascular endothelial growth factor a, collagen synthesis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1682-1692. doi: https://doi.org/10.1167/iovs.17-22694

ARVO Annual Meeting Abstract June 2017

A single dose of layer-by-layer nanoparticles prolongs endogenous gene silencing for the treatment of fibrosis

Yang Fei Tan; Li-Fong Seet; Subbu S Venkatraman; Tina T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4950. doi:

Anatomy and Pathology/Oncology January 2017

Altered Anterior Segment Biometric Parameters in Mice Deficient in SPARC

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Henrietta Ho; Hla M. Htoon; Gary Hin-Fai Yam; Li Zhen Toh; Nyein Chan Lwin; Stephanie Chu; Ying Shi Lee; Tina T. Wong; Li-Fong Seet
TAGS: anterior chamber of eye, biometry, mice, sparc study, immune reconstitution inflammatory syndrome, collagen, iris
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):386-393. doi: https://doi.org/10.1167/iovs.16-20261

ARVO Annual Meeting Abstract September 2016

Collagen VIII and XI as Biomarkers for Post-operative Conjunctival Fibrosis

Tina T Wong; Li Zhen Toh; Stephanie Chu; Jocelyn Chua; Li Fong Seet

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2925. doi:

ARVO Annual Meeting Abstract September 2016

Anti-fibrotic effect of a multilayered nanoparticle system for delivery of siSPARC in a mouse model of experimental glaucoma surgery

Yang Fei Tan; Li Fong Seet; Li Zhen Toh; Subbu Venkatraman; Tina T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2930. doi:

ARVO Annual Meeting Abstract September 2016

Valproic acid promotes inflammation in conjunctival wound healing

Li-Fong Seet; Li Zhen Toh; Tina T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3502. doi:

ARVO Annual Meeting Abstract September 2016

Increased aquaporin-1 expression in the iris is associated with raised intraocular pressure

Rachel S Chong; Li Fong Seet; Stephanie Chu; Li Zhen Toh; Tina T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6000. doi:

ARVO Annual Meeting Abstract September 2016

Anterior chamber anatomy is altered in SPARC-deficient mice

Henrietta Ho; Hla Myint Htoon; Li Zhen Toh; Chan Nyein Lwin; Tina T Wong; Li Fong Seet

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):228. doi:

ARVO Annual Meeting Abstract June 2015

Differential iridial gene expression as a novel tool for glaucoma diagnosis

Tina T Wong; Arun Naryanaswamy; Henrietta Ho; Hla Myint Htoon; Monisha nongpuir; Li-Fong Seet

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3686. doi:

ARVO Annual Meeting Abstract June 2013

SPARC Deficiency Prolongs Bleb Survival In A Mouse Model Of Glaucoma Filtration Surgery By Attenuating Pro-inflammatory and Pro-fibrotic Gene Expression

Tina Wong; Sharon Finger; Li-Fong Seet

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2136. doi:

ARVO Annual Meeting Abstract June 2013

Novel Insight into the Inflammatory and Cellular Responses following Experimental Glaucoma Surgery: a Roadmap for Inhibiting Fibrosis

Li-Fong Seet; Tina Wong

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2140. doi:

Cornea June 2012

Depletion of SLC4A11 Causes Cell Death by Apoptosis in an Immortalized Human Corneal Endothelial Cell Line

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Jun Liu; Li-Fong Seet; Li Wei Koh; Anandalakshmi Venkatraman; Divya Venkataraman; Rajiv R. Mohan; Jeppe Praetorius; Joseph A. Bonanno; Tin Aung; Eranga N. Vithana
TAGS: apoptosis, cell death, cornea, endothelial cells, polymerase chain reaction, genes
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):3270-3279. doi: https://doi.org/10.1167/iovs.11-8724

ARVO Annual Meeting Abstract March 2012

Bevacizumab Prolongs Bleb Survival In A Mouse Model Of Glaucoma Filtration Surgery By Attenuating Pro-fibrotic Gene Expression

Li-Fong Seet; Sharon N. Finger; Tina T. Wong

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6353. doi:

Anatomy and Pathology/Oncology February 2012

Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium

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Li-Fong Seet; Louis Tong; Roseline Su; Tina T. Wong
TAGS: pterygium, sparc study, stromelysin 1, pathogenesis, conjunctiva
Invest. Ophthalmol. Vis. Sci.. 2012; 53(2):587-595. doi: https://doi.org/10.1167/iovs.11-7941

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

The Etiology of Pterygium: Effect of UV, Wounding or Inflammation on Conjunctival Fibroblast Gene Expression

Li-Fong Seet; Shang-Juan Yu; Roseline S. Su; Tina T. Wong

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3371. doi:

ARVO Annual Meeting Abstract April 2011

In Vitro Expansion Of Mesenchymal Stem Cell-like Cells From The Human Trabecular Meshwork

Tina T. Wong; Padmapriya Sathiyanathan; Stephanie Chu; Li Fong Seet; Lawrence W. Stanton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5997. doi:

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Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery

Altered Iris Aquaporin Expression and Aqueous Humor Osmolality in Glaucoma

Upregulation of RelB in the Post-Operative Conjunctiva and its Role in Regulating Inflammation

Valproic Acid Reduces Inflammation following Experimental Glaucoma Surgery

Bevacizumab Promotes T-Cell–Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring

A single dose of layer-by-layer nanoparticles prolongs endogenous gene silencing for the treatment of fibrosis

Altered Anterior Segment Biometric Parameters in Mice Deficient in SPARC

Collagen VIII and XI as Biomarkers for Post-operative Conjunctival Fibrosis

Anti-fibrotic effect of a multilayered nanoparticle system for delivery of siSPARC in a mouse model of experimental glaucoma surgery

Valproic acid promotes inflammation in conjunctival wound healing

Increased aquaporin-1 expression in the iris is associated with raised intraocular pressure

Anterior chamber anatomy is altered in SPARC-deficient mice

Differential iridial gene expression as a novel tool for glaucoma diagnosis

SPARC Deficiency Prolongs Bleb Survival In A Mouse Model Of Glaucoma Filtration Surgery By Attenuating Pro-inflammatory and Pro-fibrotic Gene Expression

Novel Insight into the Inflammatory and Cellular Responses following Experimental Glaucoma Surgery: a Roadmap for Inhibiting Fibrosis

Depletion of SLC4A11 Causes Cell Death by Apoptosis in an Immortalized Human Corneal Endothelial Cell Line

Bevacizumab Prolongs Bleb Survival In A Mouse Model Of Glaucoma Filtration Surgery By Attenuating Pro-fibrotic Gene Expression

Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium

The Etiology of Pterygium: Effect of UV, Wounding or Inflammation on Conjunctival Fibroblast Gene Expression

In Vitro Expansion Of Mesenchymal Stem Cell-like Cells From The Human Trabecular Meshwork

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