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ARVO Annual Meeting Abstract June 2024

A deep phenotyping study in mouse and iPSC models to understand the interplay between neurons and oligodendroglia in optic neuropathy in Wolfram syndrome

Lies De Groef; Karan Ahuja; Marjan Vandenabeele; Arefe Nami; Catherine Verfaillie; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2461.

ARVO Annual Meeting Abstract June 2024

Intravitreal injected lipid nanoparticles for efficient and non-immunogenic mRNA delivery to the retina

Katrien Remaut; Helena Vanluchene; Laura Raes; Karen Peynshaert; Lien Veys; Kyra De Smedt; Emily De Lombaerde; Bruno De Geest; Niek Sanders; Lieve K M Moons; Koen Raemdonck; Lies De Groef

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3983.

Retina October 2021

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model

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Tine Van Bergen; Tjing-Tjing Hu; Karis Little; Lies De Groef; Lieve Moons; Alan W. Stitt; Elke Vermassen; Jean H. M. Feyen
TAGS: diabetes mellitus, plasma kallikrein, eye, peptides
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):18. https://doi.org/10.1167/iovs.62.13.18

ARVO Annual Meeting Abstract June 2021

Intraneuronal energy reshuffling by mitochondrial dynamics drives injury-induced axonal regeneration in adult zebrafish

An Beckers; Annelies Van Dyck; Luca Masin; Steven Bergmans; Lien Andries; Lies De Groef; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3037.

ARVO Annual Meeting Abstract June 2021

Comparative retinal imaging in mouse models of proteinopathies identifies disease-specific biomarkers

Lies De Groef; Lien Veys; Marjan Vandenabeele; Xavier Hadoux; Sophie Lemmens; Lutgarde Serneels; Jan Theunis; Bart De Strooper; Ingeborg Stalmans; Peter van Wijngaarden; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):364.

Review August 2020

Hyperspectral Imaging and the Retina: Worth the Wave?

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Sophie Lemmens; Jan Van Eijgen; Karel Van Keer; Julie Jacob; Sinéad Moylett; Lies De Groef; Toon Vancraenendonck; Patrick De Boever; Ingeborg Stalmans
TAGS: diagnostic imaging, retina, diabetes mellitus
Trans. Vis. Sci. Tech.. 2020; 9(9):9. https://doi.org/10.1167/tvst.9.9.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

A potential role for Src during early experimental diabetic retinopathy?

Jurgen Sergeys; Isabelle Etienne; Evy Lefevere; Inge Van Hove; Tine Van Bergen; Lies De Groef; Michaël Porcu; Jean Feyen; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2783.

ARVO Annual Meeting Abstract July 2019

The eye as a window to the brain: retinal characterization in a transgenic αSYN mouse model of Parkinson’s disease

Lien Veys; Marjan Vandenabeele; Veerle Baekelandt; Lieve K M Moons; Lies De Groef

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3105.

ARVO Annual Meeting Abstract July 2019

Characterising retinal microglia: A novel three-dimensional spatial statistics approach

Ishani Barai; Benjamin Davis; Li Guo; Nivedita Ravindran; Jessie Van houcke; Lieve K M Moons; Lies De Groef; M Francesca Cordeiro

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4009.

ARVO Annual Meeting Abstract July 2018

A new look on Alzheimer’s and Parkinson’s disease: in vivo imaging of neurodegenerative disease processes in the retina

Lies De Groef; Lien Veys; Marjan Vandenabeele; Lien Andries; Evy Lefevere; Luc Bousset; Chris Van den Haute; Ingeborg Stalmans; Ronald Melki; Veerle Baekelandt; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5831.

ARVO Annual Meeting Abstract July 2018

Potential and pitfalls of intravitreal injected mRNA as ocular neuroprotection strategy

Katrien Remaut; Joke Devoldere; Lies De Groef; Karen Peynshaert; Heleen Dewitte; Lieve K M Moons; Stefaan De Smedt

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6007.

ARVO Annual Meeting Abstract June 2017

Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease

Katja Wosikowski; Inge van Hoven; Jooseppi Puranen; Lies de Groef; Anne Mari Haapaniemi; Jurgen Sergeys; Simon Kaja; Giedrius Kalesnykas; Lieve K M Moons; Michel Janicot

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1948.

Glaucoma November 2016

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice

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Lies De Groef; Lien Andries; Anuja Siwakoti; Emiel Geeraerts; Ilse Bollaerts; Lut Noterdaeme; Isabelle Etienne; Anna-Pia Papageorgiou; Ingeborg Stalmans; Johan Billen; Judith A. West-Mays; Lieve Moons
TAGS: aqueous humor, collagen, gelatinase b, mice, knockout, trabecular meshwork, raised intraocular pressure, drainage procedure, discharge, body substance
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):5984-5995. https://doi.org/10.1167/iovs.16-19734

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

The impact of senescence on the zebrafish’s neuroregenerative capacities

Jessie Van houcke; Ilse Bollaerts; An Beckers; Kim Lemmens; Lies De Groef; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2750.

ARVO Annual Meeting Abstract June 2015

Low TNF levels and increased glutamine synthetase expression in MMP-2 deficient mice result in decreased sensitivity to NMDA-induced retinal ganglion cell death

Lies De Groef; Roosmarijn Vandenbroucke; Manuel Salinas-Navarro; Inge Van Hove; Claude Libert; Lieve K M Moons

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3668.

ARVO Annual Meeting Abstract June 2015

The effect of aging on neuroregenerative capacities: insights from the senescent zebrafish retina

Lieve K M Moons; Jessie Van houcke; Kim Lemmens; Ilse Bollaerts; Lies De Groef; Inge Van Hove

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4965.

ARVO Annual Meeting Abstract April 2014

MMP-2 and MT1-MMP as axonal outgrowth-promoting molecules in the neuroretina

Lieve K M Moons; Tom Buyens; Kim Lemmens; Manuel Salinas-Navarro; Niels Behrendt; Inge Van Hove; Djoere Gaublomme; Lies De Groef

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3515.

ARVO Annual Meeting Abstract April 2014

MMP-3 EXPRESSION IN THE DAMAGED MOUSE RETINA: A ROLE IN GLIAL REACTIVITY?

Manuel Salinas-Navarro; Lies De Groef; Eline Dekeyster; Ingeborg Stalmans; Inge Van Hove; Lieve K M Moons; Department of Biology, Laboratory for Neural Circuit Development and Regeneration, KU Leuven, Leuven, Belgium

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4472.

Review March 2014

MMPs in the Neuroretina and Optic Nerve: Modulators of Glaucoma Pathogenesis and Repair?

PDF

Lies De Groef; Inge Van Hove; Eline Dekeyster; Ingeborg Stalmans; Lieve Moons
TAGS: glaucoma, matrix metalloproteinases, optic nerve, retina, pathogenesis
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1953-1964. https://doi.org/10.1167/iovs.13-13630

Review November 2013

MMPs in the Trabecular Meshwork: Promising Targets for Future Glaucoma Therapies?

PDF

Lies De Groef; Inge Van Hove; Eline Dekeyster; Ingeborg Stalmans; Lieve Moons
TAGS: glaucoma, matrix metalloproteinases, trabecular meshwork, aqueous humor
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7756-7763. https://doi.org/10.1167/iovs.13-13088

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A deep phenotyping study in mouse and iPSC models to understand the interplay between neurons and oligodendroglia in optic neuropathy in Wolfram syndrome

Intravitreal injected lipid nanoparticles for efficient and non-immunogenic mRNA delivery to the retina

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model

Intraneuronal energy reshuffling by mitochondrial dynamics drives injury-induced axonal regeneration in adult zebrafish

Comparative retinal imaging in mouse models of proteinopathies identifies disease-specific biomarkers

Hyperspectral Imaging and the Retina: Worth the Wave?

A potential role for Src during early experimental diabetic retinopathy?

The eye as a window to the brain: retinal characterization in a transgenic αSYN mouse model of Parkinson’s disease

Characterising retinal microglia: A novel three-dimensional spatial statistics approach

A new look on Alzheimer’s and Parkinson’s disease: in vivo imaging of neurodegenerative disease processes in the retina

Potential and pitfalls of intravitreal injected mRNA as ocular neuroprotection strategy

Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice

The impact of senescence on the zebrafish’s neuroregenerative capacities

Low TNF levels and increased glutamine synthetase expression in MMP-2 deficient mice result in decreased sensitivity to NMDA-induced retinal ganglion cell death

The effect of aging on neuroregenerative capacities: insights from the senescent zebrafish retina

MMP-2 and MT1-MMP as axonal outgrowth-promoting molecules in the neuroretina

MMP-3 EXPRESSION IN THE DAMAGED MOUSE RETINA: A ROLE IN GLIAL REACTIVITY?

MMPs in the Neuroretina and Optic Nerve: Modulators of Glaucoma Pathogenesis and Repair?

MMPs in the Trabecular Meshwork: Promising Targets for Future Glaucoma Therapies?

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