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Retina June 2025

Retinal Vessel Geometry and Retinal Abnormalities in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

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Wenbo Zhang; Xuecong Zhou; Jiacheng Liu; Tian Tian; Yu Guo; Chen Ling; Jingjing Xu; Qijie Wei; Yang Liu; Yuan Wu
TAGS: arterial disease, brain, cadasil, infarction, leukoencephalopathies, retinal vessels, subcortical
Trans. Vis. Sci. Tech.. 2025; 14(6):17. https://doi.org/10.1167/tvst.14.6.17

Cornea December 2024

Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease

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Zhiwei Zha; Decheng Xiao; Zihao Liu; Fangli Peng; Xunjie Shang; Zhenzhen Sun; Yang Liu; Wei Chen
TAGS: cyclophosphamide, doxorubicin, prednisone, and vincristine, dry eye syndromes, nlr family, pyrin domain-containing 3 protein, signal pathway, signal transduction pathways, stress, mice, endoplasmic reticulum, inflammasomes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):34. https://doi.org/10.1167/iovs.65.14.34

Includes: Supplemental Content

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Glaucoma July 2024

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

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Nan Zhang; Pengyu Zhang; Xizhi Deng; Min Zhu; Yixin Hu; Dongxiao Ji; Lufan Li; Yang Liu; Wen Zeng; Min Ke
TAGS: extracellular matrix, glaucoma, glucocorticoids, mitochondria, mitochondrial toxicity, niacinamide, trabecular meshwork, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):1. https://doi.org/10.1167/iovs.65.8.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Dark Without Pressure Prevalence and Clinical Features in Patients Seen in An Ophthalmology Center in China

Junmeng Li; Ruilin Zhu; Yuwei Wang; Liu Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5127.

ARVO Annual Meeting Abstract June 2024

Single Cell-RNA Sequencing Analysis of Cone Photoreceptors in Mice After Retinal detachment

Yuwei Wang; Ruilin Zhu; Jianchen Hao; Junmeng Li; Chen Xing; Liu Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4745.

ARVO Annual Meeting Abstract June 2024

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

Yang LIU; Megumi HONJO; Reiko YAMAGISHI; Makoto AIHARA

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):847.

ARVO Annual Meeting Abstract June 2024

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

Yen-Chiao Wang; Yuan Yong; Olivia Zolnik; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):520.

ARVO Annual Meeting Abstract June 2024

The role of Smad4 in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil Ghag; Winston Kao; Shizuya Saika; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):502.

ARVO Annual Meeting Abstract June 2024

Ultrastructure and morphology of healing corneal stroma in a keratocyte-specific hyaluronan synthases 2-deficient mouse

Ai Matsushita; Takayoshi Sumioka; Yuka Okada; Hiroki Iwanishi; Masayasu Miyajima; Chia-Yang Liu; Winston Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):485.

ARVO Annual Meeting Abstract June 2024

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

chia-yang liu; Yong Yuan; Yen-Chiao Wang; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3647.

ARVO Annual Meeting Abstract June 2024

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 1 year follow-up of an investigator initiated trial

Yang Liu; Minlu Song; Jingyang Feng; Lihong Li; Fenghua Wang; Yuanyuan Gong; Hong Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4378.

ARVO Annual Meeting Abstract June 2024

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Junran Sun; Yang Liu; Yidong Wu; Tong Li; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5332.

ARVO Annual Meeting Abstract June 2024

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 9-month follow-up of a phase 1 clinical trial

Minlu Song; Yang Liu; Jingyang Feng; Yuanyuan Gong; Hong Wang; Lihong Li; Fenghua Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6107.

Retina March 2024

Choroidal Vascularity Index and Choroidal Structural Changes in Children With Nephrotic Syndrome

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Wenbo Zhang; Junmeng Li; Lei Zhu; Shuang Zeng; Yanye Lu; Yadi Zhang; Xiaopeng Gu; Hailong Wu; Liu Yang
TAGS: child, nephrotic syndrome, cortical blindness, cardiovascular imaging
Trans. Vis. Sci. Tech.. 2024; 13(3):18. https://doi.org/10.1167/tvst.13.3.18

Biochemistry and Molecular Biology February 2024

Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function

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Hou-Zhi Yang; Donghai Zhuo; Zongyu Huang; Gan Luo; Shuang Liang; Yonggang Fan; Ying Zhao; Xinxin Lv; Caizhen Qiu; Lingzhu Zhang; Yang Liu; Tianwei Sun; Xu Chen; Shan-Shan Li; Xin Jin
TAGS: zebrafish, congenital abnormality, vision, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):31. https://doi.org/10.1167/iovs.65.2.31

ARVO Imaging in the Eye Conference Abstract June 2023

Cellular Resolution Imaging of the Cornea: From Disease Mouse Models to Humans

Patrice Tankam; Hadiya Pattan; Xiao Liu; Reddikumar Maddipatla; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PP0021.

ARVO Annual Meeting Abstract June 2023

Role of Lumican on TgfβR Signaling in The Healing of Deep Corneal Epithelial Debridement

Winston Kao; Jianhua Zhang; Shingo Yasuda; Yong Yuan; Shizuya Saika; chia-yang liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):506.

ARVO Annual Meeting Abstract June 2023

Inhibition of Corneal Neovascularization (CoNV) by Topical Administration of VEGF Trap in Rabbit

lihong song; Duo Sun; Yang Liu; Jintai Cao; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1734.

ARVO Annual Meeting Abstract June 2023

The role of TGFbR1 signal in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil; Winston Kao; Shizuya Saika; chia-yang liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3163.

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Retinal Vessel Geometry and Retinal Abnormalities in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

Dark Without Pressure Prevalence and Clinical Features in Patients Seen in An Ophthalmology Center in China

Single Cell-RNA Sequencing Analysis of Cone Photoreceptors in Mice After Retinal detachment

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

The role of Smad4 in corneal development and homeostasis

Ultrastructure and morphology of healing corneal stroma in a keratocyte-specific hyaluronan synthases 2-deficient mouse

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 1 year follow-up of an investigator initiated trial

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 9-month follow-up of a phase 1 clinical trial

Choroidal Vascularity Index and Choroidal Structural Changes in Children With Nephrotic Syndrome

Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function

Cellular Resolution Imaging of the Cornea: From Disease Mouse Models to Humans

Role of Lumican on TgfβR Signaling in The Healing of Deep Corneal Epithelial Debridement

Inhibition of Corneal Neovascularization (CoNV) by Topical Administration of VEGF Trap in Rabbit

The role of TGFbR1 signal in corneal development and homeostasis

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