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Biochemistry and Molecular Biology April 2024

Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease

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Yang Tang; Shengqian Dou; Chao Wei; Ziwen Sun; Di Sun; Qingjun Zhou; Lixin Xie
TAGS: acinar cells, cell nucleus, dry eye syndromes, genes, heterogeneity, immunologic cells, lacrimal gland, langer-giedion syndrome, mice, scopolamine
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):46. https://doi.org/10.1167/iovs.65.4.46

Includes: Supplemental Content

Cornea January 2023

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

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Lili Ran; Jing Feng; Xia Qi; Ting Liu; Benxiang Qi; Kai Jiang; Zhenzhen Zhang; Yang Yu; Qingjun Zhou; Lixin Xie
TAGS: cornea, epithelium, mice, wound healing
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):19. https://doi.org/10.1167/iovs.64.1.19

Includes: Supplemental Content

Cornea March 2022

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

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Chen Chen; Bin Zhang; Junfa Xue; Zongyi Li; Shengqian Dou; Huilin Chen; Qun Wang; Mingli Qu; Huifeng Wang; Yuan Zhang; Luqin Wan; Qingjun Zhou; Lixin Xie
TAGS: cornea, corneal endothelium, diabetes mellitus, endothelial dysfunction, stress, mice, endothelial cells, mitochondria, corneal edema, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):4. https://doi.org/10.1167/iovs.63.3.4

Includes: Supplemental Content

Articles August 2021

Biomechanical Effects of Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty for Keratoconus: A Finite Element Analysis

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Hua Li; Min Chen; Qingjun Zhou; Xiaojing Pan; Jun Cheng; Lin Cong; Ting Zhang; Yanling Dong; Lixin Xie
TAGS: cornea, keratoconus, keratoplasty, stress, keratoplasty, penetrating, finite element analysis, intraocular pressure
Trans. Vis. Sci. Tech.. 2021; 10(9):15. https://doi.org/10.1167/tvst.10.9.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

β2 adrenoceptor inhibition reduces the severity of Pseudomonas aeruginosa keratitis in mice

Qingjun Zhou; lixin Xie; Xiubin Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):902.

ARVO Annual Meeting Abstract July 2018

Role of impaired platelet function and PDGF expression in diabetic corneal epithelial regeneration

Yangyang Zhang; Qingjun Zhou; Lixin Xie

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4364.

Cornea June 2018

PEDF Reduces the Severity of Herpetic Simplex Keratitis in Mice

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Xiao Tian; Tongsong Wang; Songmei Zhang; Qian Wang; Xiaoli Hu; Cheng Ge; Lixin Xie; Qingjun Zhou
TAGS: cornea, human herpesvirus 1, keratitis, mice, neovascularization, pathologic, infections
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2923-2931. https://doi.org/10.1167/iovs.18-23942

Cornea August 2017

Mesenchymal Stem Cells Promote Diabetic Corneal Epithelial Wound Healing Through TSG-6–Dependent Stem Cell Activation and Macrophage Switch

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Guohu Di; Xianli Du; Xia Qi; Xiaowen Zhao; Haoyun Duan; Suxia Li; Lixin Xie; Qingjun Zhou
TAGS: cornea, diabetes mellitus, epithelium, wound healing, stem cells, macrophages, stem cell, mesenchymal
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4344-4354. https://doi.org/10.1167/iovs.17-21506

Includes: Supplemental Content

Cornea December 2015

Neuropeptide FF Promotes Recovery of Corneal Nerve Injury Associated With Hyperglycemia

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Yunhai Dai; Xiaowen Zhao; Peng Chen; Yang Yu; Ye Wang; Lixin Xie
TAGS: cornea, diabetes mellitus, hyperglycemia, mice, nerve injuries, neurons, neuropeptides, recovery of function
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7754-7765. https://doi.org/10.1167/iovs.15-16513

Includes: Supplemental Content

Cornea March 2015

MicroRNA-204-5p–Mediated Regulation of SIRT1 Contributes to the Delay of Epithelial Cell Cycle Traversal in Diabetic Corneas

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Jing Gao; Ye Wang; Xiaowen Zhao; Peng Chen; Lixin Xie
TAGS: cell cycle, cornea, corneal epithelium, diabetes mellitus, epithelial cells, micrornas, regulation, proteins, down-regulation
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1493-1504. https://doi.org/10.1167/iovs.14-15913

Includes: Supplemental Content

Genetics December 2014

Mutations in the ABCA3 Gene Are Associated With Cataract-Microcornea Syndrome

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Peng Chen; Yunhai Dai; Xiaoming Wu; Ye Wang; Shiying Sun; Jingjing Xiao; Qingyan Zhang; Liping Guan; Xiaowen Zhao; Xiaodan Hao; Renhua Wu; Lixin Xie
TAGS: cataract, cataract-microcornea syndrome, genes, microcornea, mutation, syndrome, family
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8031-8043. https://doi.org/10.1167/iovs.14-14098

ARVO Annual Meeting Abstract April 2014

SIRT1-responsive microRNA-182 contributes to a regulatory loop for recovery of peripheral nerve injury in experimental diabetic neuropathy

Ye Wang; Lixin Xie

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4610.

ARVO Annual Meeting Abstract April 2014

Substance P promotes diabetic corneal epithelial wound healing by rescuing NK-1 receptor expression

Yang Lingling; Guohu Di; Qi Xia; Mingli Qu; Yao Wang; Haoyun Duan; Lixin Xie; Qingjun Zhou

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4699.

ARVO Annual Meeting Abstract June 2013

Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway

Ye Wang; Lixin Xie

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2563.

Cornea May 2013

Overexpression of SIRT1 Promotes High Glucose–Attenuated Corneal Epithelial Wound Healing via p53 Regulation of the IGFBP3/IGF-1R/AKT Pathway

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Ye Wang; Xiaowen Zhao; Daling Shi; Peng Chen; Yang Yu; Lingling Yang; Lixin Xie
TAGS: akt signaling pathway, attenuation, cornea, epithelium, glucose, hyperglycemic agents, insulin-like growth factor binding protein 3, insulin-like-growth factor i receptor, protein overexpression, regulation
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3806-3814. https://doi.org/10.1167/iovs.13-12091

Includes: Supplemental Content

Genetics May 2011

A Novel Locus for Congenital Simple Microphthalmia Family Mapping to 17p12-q12

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Zhengmao Hu; Changhong Yu; Jingzhi Li; Yiqiang Wang; Deyuan Liu; Xinying Xiang; Wei Su; Qian Pan; Lixin Xie; Kun Xia
TAGS: family, microphthalmos, haplotypes, genome
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3425-3429. https://doi.org/10.1167/iovs.10-6747

Cornea June 2009

Role of Adaptive Immunity in the Pathogenesis of Candida albicans Keratitis

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Hongbo Zhang; Hao Chen; Jingyi Niu; Yiqiang Wang; Lixin Xie
TAGS: acquired immunity, candida albicans, immune response, keratitis, mice, pathogenesis, cornea, cytokine, immunoglobulins, immunoglobulin a
Invest. Ophthalmol. Vis. Sci.. 2009; 50(6):2653-2659. https://doi.org/10.1167/iovs.08-3104

Cornea May 2009

Potential Role of Macrophages in Experimental Keratomycosis

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Jianzhang Hu; Ye Wang; Lixin Xie
TAGS: cornea, cytokine, lip, macrophages, fungal keratitis, toll-like receptor 4, mice, vaccination, corneal infections
Invest. Ophthalmol. Vis. Sci.. 2009; 50(5):2087-2094. https://doi.org/10.1167/iovs.07-1237

Cornea August 2006

Sustained Intraocular Rapamycin Delivery Effectively Prevents High-Risk Corneal Allograft Rejection and Neovascularization in Rabbits

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Weiyun Shi; Hua Gao; Lixin Xie; Shenguo Wang
TAGS: allografting, rapamycin, neovascularization, pathologic, cornea, rejection (psychology), eyedrops, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2006; 47(8):3339-3344. https://doi.org/10.1167/iovs.05-1425

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Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

Biomechanical Effects of Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty for Keratoconus: A Finite Element Analysis

β2 adrenoceptor inhibition reduces the severity of Pseudomonas aeruginosa keratitis in mice

Role of impaired platelet function and PDGF expression in diabetic corneal epithelial regeneration

PEDF Reduces the Severity of Herpetic Simplex Keratitis in Mice

Mesenchymal Stem Cells Promote Diabetic Corneal Epithelial Wound Healing Through TSG-6–Dependent Stem Cell Activation and Macrophage Switch

Neuropeptide FF Promotes Recovery of Corneal Nerve Injury Associated With Hyperglycemia

MicroRNA-204-5p–Mediated Regulation of SIRT1 Contributes to the Delay of Epithelial Cell Cycle Traversal in Diabetic Corneas

Mutations in the ABCA3 Gene Are Associated With Cataract-Microcornea Syndrome

SIRT1-responsive microRNA-182 contributes to a regulatory loop for recovery of peripheral nerve injury in experimental diabetic neuropathy

Substance P promotes diabetic corneal epithelial wound healing by rescuing NK-1 receptor expression

Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway

Overexpression of SIRT1 Promotes High Glucose–Attenuated Corneal Epithelial Wound Healing via p53 Regulation of the IGFBP3/IGF-1R/AKT Pathway

A Novel Locus for Congenital Simple Microphthalmia Family Mapping to 17p12-q12

Role of Adaptive Immunity in the Pathogenesis of Candida albicans Keratitis

Potential Role of Macrophages in Experimental Keratomycosis

Sustained Intraocular Rapamycin Delivery Effectively Prevents High-Risk Corneal Allograft Rejection and Neovascularization in Rabbits

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