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Meeting Abstract (13)
Journal Articles (2)

Journal

Investigative Ophthalmology & Visual Science (13)
Translational Vision Science & Technology (2)

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ARVO Annual Meeting Abstract (13)
Articles (2)

Topics

Eye Anatomy and Disorders (2)
Genetics (2)
Translational Research (2)
Imaging (1)
Nanotechnology and Regenerative Medicine (1)
Retina (1)
Retinal Imaging (1)
Surgery (1)

Tags

cell survival (1)
choroideremia (1)
disease progression (1)
dyes (1)
gene therapy (1)
genes (1)
injections (1)
proteins (1)
spatial vectors (1)
surgical procedures, operative (1)

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Articles July 2021

Expression of Rab Prenylation Pathway Genes and Relation to Disease Progression in Choroideremia

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Lewis E. Fry; Maria I. Patrício; Jasleen K. Jolly; Kanmin Xue; Robert E. MacLaren
TAGS: choroideremia, disease progression, genes, tissue degeneration, proteins
Trans. Vis. Sci. Tech.. 2021; 10(8):12. https://doi.org/10.1167/tvst.10.8.12

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Retinal Gene Therapy for Choroideremia in a Multicenter Dose Escalation Phase I/II Clinical Trial

Robert E MacLaren; Kanmin Xue; Alun R Barnard; Maria In?s Patrício; Thomas L Edwards; Susan Downes; Andrew Lotery; Graeme Black; Andrew Webster; Jasleen K Jolly; Miguel C Seabra

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1195.

ARVO Annual Meeting Abstract July 2018

Pathological donor splice site mutations beyond the dinucleotide canonical sequence in choroideremia

Lewis Fry; Maria In?s Patrício; Jonathan Williams; Penny Clouston; Kanmin Xue; Alun R Barnard; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3493.

ARVO Annual Meeting Abstract July 2018

Biocompatibility and stability of an AAV vector for choroideremia gene therapy following passage through its surgical device

Maria In?s Patrício; Cristina Martinez-Fernandez Dela Camara; Christopher I Cox; Clare Blue; Alun R Barnard; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4541.

ARVO Annual Meeting Abstract July 2018

Hydroxychloroquine enhances the efficacy of retinal gene therapy

Laurel Clare Chandler; Alun R Barnard; Maria In?s Patrício; Kanmin Xue; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6005.

ARVO Annual Meeting Abstract July 2018

Retinal degeneration in choroideremia follows an exponential decay function

James William Aylward; Kanmin Xue; Maria In?s Patrício; Jasleen K Jolly; Jonathan Charles Wood; Jonathan Brett; Kirti Jasani; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6060.

ARVO Annual Meeting Abstract July 2018

An optimized AAV vector for rod-specific gene expression

Harry Otway Orlans; Michelle McClements; Maria In?s Patrício; Alun R Barnard; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4534.

Articles July 2017

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

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Anna P. Salvetti; Maria I. Patrício; Alun R. Barnard; Harry O. Orlans; Doron G. Hickey; Robert E. MacLaren
TAGS: dyes, gene therapy, surgical procedures, operative, spatial vectors, cell survival, injections, toxic effect
Trans. Vis. Sci. Tech.. 2017; 6(4):4. https://doi.org/10.1167/tvst.6.4.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

The human retinoblastoma WERI-Rb1 cell line as an in vitro model for photoreceptor-specific AAV transgene expression

Cristina Martinez-Fernandez de la Camar; Maria In�s Patrício; Michelle E. McClements; Alun R Barnard; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1773.

ARVO Annual Meeting Abstract June 2017

Investigation of intracellular innate immune responses to AAV gene therapy in the retina.

Laurel Clare Chandler; Howell Fu; Sarah Caddy; Alun R Barnard; Maria In�s Patrício; Leo James; Cristina Rada; Robert E MacLaren; Kanmin Xue

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4491.

ARVO Annual Meeting Abstract June 2017

Assessment of the relationship between CHM gene expression and rate of disease progression in choroideremia

Maria In�s Patrício; Kanmin Xue; Laurel C Chandler; Alun R Barnard; Jasleen K Jolly; Thomas Edwards; Michelle E. McClements; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4528.

ARVO Annual Meeting Abstract September 2016

Impact of vital dyes on transduction efficiency of AAV vectors used in retinal gene therapy

Anna Paola Salvetti; Maria Ines Patricio; Alun R Barnard; Robert Maclaren

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):104.

ARVO Annual Meeting Abstract September 2016

Transgene expression in the retina following AAV transduction: the WPRE effect

Maria Ines Patricio; Alun R Barnard; Harry Otway Orlans; Michelle McClements; Robert Maclaren

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1152.

ARVO Annual Meeting Abstract September 2016

Functional expression of Bestrophin-1 in vitro following transduction with viral vectors.

Shaun Roger Wood; Michelle McClements; Maria Ines Patricio; Robert E MacLaren; Carolina Uggenti; Sumathi Sekaran; Forbes D Manson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1174.

ARVO Annual Meeting Abstract September 2016

Quantification of Fluorescence in Retinal Sections by Confocal Microscopy

Harry Otway Orlans; Maria Ines Patricio; Alun R Barnard; Robert Maclaren

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1706.

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Online ISSN: 2164-2591

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2025 Association for Research in Vision and Ophthalmology.

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