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ARVO Annual Meeting Abstract June 2024

ARMS2 A69S is associated with an increased level of retinal degeneration in a co-culture model for AMD

Merve Sen; Emanuel ten Brink; Kevin Elsner; Ellen Kilger; Angela Armento; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):770.

ARVO Annual Meeting Abstract June 2024

Complement Factor H (CFH) Y402H polymorphism alters the endoplasmic reticulum (ER) stress response in iPSC-RPE cells

Angela Armento; Inga Sonntag; Merve Sen; Simon John Clark; Rosario Fernandez-godino; Berta de la Cerda; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):727.

ARVO Annual Meeting Abstract June 2024

Valosin-Containing Protein Inhibition: Neuroprotective Strategy Against Retinal Degeneration in Porcine and Human Models.

Ana Cristina Almansa Garcia; Bowen Cao; Angela Armento; Merve Sen; Ellen Kilger; Anne-Sophie Petremann Dumé; Sylvia Bolz; Christine Henes; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1240.

ARVO Annual Meeting Abstract June 2024

Pharmacological inhibition or genetic inactivation of ERAD effector VCP suppresses Rho ΔI255 -associated retinal degeneration

Bowen Cao; Johanna Valentina Dahlen; Ana Cristina Almansa Garcia; Merve Sen; Tina Beyer; Ellen Kilger; Francois Paquet-Durand; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2198.

ARVO Annual Meeting Abstract June 2024

Inhibition of valosin-containing protein (VCP) prevents retinal degeneration in P23H transgenic rats, a model for autosomal dominant RP.

Blanca Arango-Gonzalez; Bowen Cao; Ana Cristina Almansa Garcia; Ellen Kilger; Angela Armento; Rosellina Guarascio; Kalliopi Ziaka; Kwan-Leong Hau; Hannah Poultney; Rowan Asfahani; Anne-Sophie Petremann Dumé; Sylvia Bolz; Michael E Cheetham; Merve Sen; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4735.

ARVO Annual Meeting Abstract June 2024

Cathepsin-G accumulation in Bruch’s membrane may alter complement activation through the degradation of FHRs and C3b

Jiaqi Tang; Sonika Rathi; Tina Beyer; Karsten Boldt; Marius Ueffing; Simon John Clark

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5001.

ARVO Annual Meeting Abstract June 2023

Complement Factor H (CFH) Y402H polymorphism alters the stress response of iPSC-RPE cells and leads to retinal degeneration in a novel co-culture model for Age-related Macular Degeneration (AMD)

Angela Armento; Inga Sonntag; Merve Sen; Simon J Clark; rosario fernandez-godino; Berta de la Cerda; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5074.

ARVO Annual Meeting Abstract June 2023

Molecular insights and treatment of IFT140 -mediated retinal dystrophy in iPSCs-derived retinal organoids and RPE

Julio Cesar Corral Serrano; Nele Schwarz; Karsten Boldt; Katarina Jovanovic; Daniele Ottaviani; Isabelle Perrault; marius ueffing; Michael E Cheetham

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):478.

ARVO Annual Meeting Abstract June 2023

Safety and Vision Outcomes of subretinal gene supplementation therapy in PDE6A -associated Retinitis pigmentosa

Felix Friedrich Lambert Reichel; Stylianos Michalakis; Dominik M Fischer; laura kuehlewein; Tobias Peters; Susanne Kohl; Karl-Ulrich Bartz-Schmidt; Marius Ueffing; Eberhart Zrenner; Martin Biel; Katarina Stingl; Bernd Wissinger

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):782.

ARVO Annual Meeting Abstract June 2023

The autosomal dominant R ho lle256del mutation causes protein aggregation and is processed by the VCP-dependent ERAD pathway

Bowen Cao; Johanna Valentina Dahlen; Merve Sen; Tobias Leonhard; Tina Beyer; Blanca Arango Gonzalez; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1553.

ARVO Annual Meeting Abstract June 2023

Pharmacological targeting of VCP in porcine and human organotypic retinal explants.

Ana Cristina Almansa Garcia; Bowen Cao; Merve Sen; Angela Armento; Sylvia Bolz; Blanca Arango Gonzalez; marius ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1517.

ARVO Annual Meeting Abstract June 2023

Impact of the ARMS2 AMD-associated A69S polymorphism on the extracellular matrix of retinal pigment epithelium cells

Merve Sen; Angela Armento; Kevin Elsner; Ellen Kilger; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2109.

ARVO Annual Meeting Abstract June 2022

Adaptive optics ophthalmoscopy in retinitis pigmentosa: typical patterns

Friederike Charlotte Kortuem; Melanie Kempf; Laura Kuehlewein; Fadi Nasser; Constanze Kortuem; Susanne Kohl; Michel Paques; Bernd Wissinger; Marius Ueffing; Eberhart Zrenner; Katarina Stingl

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4439 – F0118.

ARVO Annual Meeting Abstract June 2021

Dissecting the disease mechanism of Leber congenital amaurosis type 5 (LCA5) using retinal affinity proteomics

Siebren Faber; Stef Letteboer; Alejandro Garanto; Katrin Junger; Tina Beyer; Jean Bennett; Marius Ueffing; Rob W.J. Collin; Karsten Boldt; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3077.

ARVO Annual Meeting Abstract June 2020

Dissecting the function of IQCB1/NPHP5, associated with retinal ciliopathies, by targeting its endogenous interactome

Ideke J.C. Lamers; Filine van den Bosch; Kim Klarenaar; Lisa Elze; Marius Ueffing; Karsten Boldt; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4008.

Articles December 2019

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

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Krunoslav T. Stingl; Laura Kuehlewein; Nicole Weisschuh; Saskia Biskup; Frans P. M. Cremers; M. Imran Khan; Carina Kelbsch; Tobias Peters; Marius Ueffing; Barbara Wilhelm; Eberhart Zrenner; Katarina Stingl
TAGS: eye, illness length, mutation, pupil reaction, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2019; 8(6):45. https://doi.org/10.1167/tvst.8.6.45

ARVO Annual Meeting Abstract July 2019

Complement factor H (CFH) loss leads to a local complement system activation and impaired cell balance in the RPE cells

Angela Armento; Sabina Honisch; Anke Jacob; Dragana Trifunovic; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1242.

ARVO Annual Meeting Abstract July 2019

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

G. Alex Ochakovski; Ahmad Zhour; Laura Kuehlewein; Susanne Kohl; Andrea Rindtorff; Karl Ulrich Bartz-Schmidt; Marius Ueffing; Eberhart Zrenner; Stylianos Michalakis; Martin Biel; Bernd Wissinger; Tobias Peters; Barbara Wilhelm; M. Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2921.

ARVO Annual Meeting Abstract July 2019

Human Retina-on-a-Chip: Merging retinal organoids with Organ-on-a-Chip technology

Kevin Achberger; Christopher Probst; Jasmin Haderspeck; Sylvia Bolz; Virginia Cora; Johanna Chuchuy; Lena Antkowiak; Wadood Haq; Marius Ueffing; Peter Loskill; Stefan Liebau

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3317.

ARVO Annual Meeting Abstract July 2019

Inhibition of VCP structurally and functionally reconstitutes photoreceptor cells in Rh P23H organotypic retina cultures

Blanca Arango-Gonzalez; Merve Sen; Tsui-Fen Chou; Ray Deshaies; Sylvia Bolz; Wadood Haq; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4878.

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ARMS2 A69S is associated with an increased level of retinal degeneration in a co-culture model for AMD

Complement Factor H (CFH) Y402H polymorphism alters the endoplasmic reticulum (ER) stress response in iPSC-RPE cells

Valosin-Containing Protein Inhibition: Neuroprotective Strategy Against Retinal Degeneration in Porcine and Human Models.

Pharmacological inhibition or genetic inactivation of ERAD effector VCP suppresses Rho ΔI255 -associated retinal degeneration

Inhibition of valosin-containing protein (VCP) prevents retinal degeneration in P23H transgenic rats, a model for autosomal dominant RP.

Cathepsin-G accumulation in Bruch’s membrane may alter complement activation through the degradation of FHRs and C3b

Complement Factor H (CFH) Y402H polymorphism alters the stress response of iPSC-RPE cells and leads to retinal degeneration in a novel co-culture model for Age-related Macular Degeneration (AMD)

Molecular insights and treatment of IFT140 -mediated retinal dystrophy in iPSCs-derived retinal organoids and RPE

Safety and Vision Outcomes of subretinal gene supplementation therapy in PDE6A -associated Retinitis pigmentosa

The autosomal dominant R ho lle256del mutation causes protein aggregation and is processed by the VCP-dependent ERAD pathway

Pharmacological targeting of VCP in porcine and human organotypic retinal explants.

Impact of the ARMS2 AMD-associated A69S polymorphism on the extracellular matrix of retinal pigment epithelium cells

Adaptive optics ophthalmoscopy in retinitis pigmentosa: typical patterns

Dissecting the disease mechanism of Leber congenital amaurosis type 5 (LCA5) using retinal affinity proteomics

Dissecting the function of IQCB1/NPHP5, associated with retinal ciliopathies, by targeting its endogenous interactome

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

Complement factor H (CFH) loss leads to a local complement system activation and impaired cell balance in the RPE cells

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

Human Retina-on-a-Chip: Merging retinal organoids with Organ-on-a-Chip technology

Inhibition of VCP structurally and functionally reconstitutes photoreceptor cells in Rh P23H organotypic retina cultures

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