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Retina April 2025

Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

PDF

Lukas Goerdt; Mark E. Clark; Tracy N. Thomas; Liyan Gao; Gerald McGwin, Jr.; Martin Hammer; Jason N. Crosson; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, diagnostic imaging, eye, fluorescence, ophthalmoscopy, vision, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):56. https://doi.org/10.1167/iovs.66.4.56

Includes: Supplemental Content

Retina March 2025

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

PDF

Lukas Goerdt; Andreas Berlin; Liyan Gao; Thomas A. Swain; Sarah S. Kim; Gerald McGwin; Mark E. Clark; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: aging, autofluorescence, eye, lutein, pigment, maps, meridians, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):61. https://doi.org/10.1167/iovs.66.3.61

Includes: Supplemental Content

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

PDF

Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Retina August 2024

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

PDF

Lukas Goerdt; Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio; Deepayan Kar
TAGS: digestive tract decontamination, rod photoreceptors, vision, eye, aging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):25. https://doi.org/10.1167/iovs.65.10.25

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2024

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

PDF

Deepayan Kar; Mohymina Amjad; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Kenneth R. Sloan; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, aging, fovea centralis, vision, impairment, rod photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):40. https://doi.org/10.1167/iovs.65.8.40

ARVO Annual Meeting Abstract June 2024

Robotic Spectral-domain versus Swept-source OCT in the association between OCT-Angiography metrics and glaucoma severity.

Massimo Antonio Fazio; Mark E Clark; Christopher A Girkin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1212.

ARVO Annual Meeting Abstract June 2024

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Cynthia Owsley; Gerald McGwin; Thomas A. Swain; Mark E Clark; Tracy N Thomas; Lucas Goerdt; Kenneth R Sloan; Emily Trittschuh; Yu Jiang; Julia Owen; Cecilia S Lee; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2267.

ARVO Annual Meeting Abstract June 2024

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Yu Jiang; Thomas A. Swain; Christine Mac Donald; Ariel Rokem; Julia P Owen; Gerald McGwin; Christine A Curcio; Kenneth R Sloan; Emily H Trittschuh; Swati Rane Levendovszky; Mark E Clark; Cynthia Owsley; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):446.

Retina May 2024

Probing Deposit-Driven Age-Related Macular Degeneration Via Thicknesses of Outer Retinal Bands and Choroid: ALSTAR2 Baseline

PDF

Mehdi Emamverdi; Charles Vatanatham; Sohaib Fasih-Ahmad; Ziyuan Wang; Zubin Mishra; Anjal Jain; Anushika Ganegoda; Mark E. Clark; Abbas Habibi; Maryam Ashrafkhorasani; Cynthia Owsley; Christine A. Curcio; Zhihong J. Hu; SriniVas R. Sadda
TAGS: age-related macular degeneration, choroid, digestive tract decontamination, drusen, eye, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):17. https://doi.org/10.1167/iovs.65.5.17

Includes: Supplemental Content

Retina May 2024

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

PDF

Cynthia Owsley; Gerald McGwin, Jr.; Thomas A. Swain; Mark E. Clark; Tracy N. Thomas; Lukas Goerdt; Kenneth R. Sloan; Emily H. Trittschuh; Yu Jiang; Julia P. Owen; Cecilia S. Lee; Christine A. Curcio
TAGS: age-related macular degeneration, aging, cognition, cognitive ability, mental processes, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):16. https://doi.org/10.1167/iovs.65.5.16

Retina February 2024

Potential Structural Biomarkers in 3D Images Validated by the First Functional Biomarker for Early Age-Related Macular Degeneration – ALSTAR2 Baseline

PDF

Sohaib Fasih-Ahmad; Ziyuan Wang; Zubin Mishra; Charles Vatanatham; Mark E. Clark; Thomas A. Swain; Christine A. Curcio; Cynthia Owsley; SriniVas R. Sadda; Zhihong Jewel Hu
TAGS: age-related macular degeneration, biological markers, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):1. https://doi.org/10.1167/iovs.65.2.1

Includes: Supplemental Content

Glaucoma December 2023

Displacement of the Lamina Cribrosa With Acute Intraocular Pressure Increase in Brain-Dead Organ Donors

PDF

Christopher A. Girkin; Mary A. Garner; Stuart K. Gardiner; Mark E. Clark; Meredith Hubbard; Udayakumar Karuppanan; Gianfranco Bianco; Luigi Bruno; Massimo A. Fazio
TAGS: brain death, intraocular pressure, organ donation, optic disk, cribriform plate, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):19. https://doi.org/10.1167/iovs.64.15.19

Includes: Multimedia, Supplemental Content

Multidisciplinary Ophthalmic Imaging September 2023

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

PDF

Deepayan Kar; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, dark adaptation, drusen, eye, fluid flow, impairment, rod photoreceptors, vision, visual impairment, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):41. https://doi.org/10.1167/iovs.64.12.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Anatomic Correlates of Microperimetric Sensitivity in Early (e-AMD) and Intermediate Age-Related Macular Degeneration (i-AMD): ALSTAR2 Baseline Cohort

Chaiyaporn C Vatanatham; Ziyuan Wang; Zubin Mishra; Sohaib Fasih-Ahmad; Mark E. Clark; Christine A. Curcio; Cynthia Owsley; Zhihong Hu; SriniVas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):OD82.

ARVO Annual Meeting Abstract June 2023

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

Deepayan Kar; Giulia Corradetti; Mohymina Amjad; Thomas A. Swain; Mark E. Clark; Gerald McGwin; Cynthia Owsley; Kenneth R Sloan; SriniVas R Sadda; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):921.

ARVO Annual Meeting Abstract June 2023

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Cynthia Owsley; Jason Neal Crosson; Kenneth R Sloan; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5005.

ARVO Annual Meeting Abstract June 2023

Antidepressant medication use is associated with impaired rod-mediated visual functions in normal aging and early and intermediate AMD: ALSTAR2 baseline

Thomas A. Swain; Mark E. Clark; Christine A. Curcio; Cynthia Owsley; Gerald McGwin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5068.

ARVO Annual Meeting Abstract June 2023

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

Kenneth R Sloan; Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Jason Neal Crosson; Cynthia Owsley; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5021.

ARVO Annual Meeting Abstract June 2023

Relationship between Delayed RMDA and the Ellipsoid and Interdigitation Zones in Age-related Macular Degeneration (AMD): ALSTAR2 baseline

Sohaib Fasih-Ahmad; Ziyuan Wang; Zubin Mishra; Charles Vatanatham; Mark E. Clark; Christine A. Curcio; Cynthia Owsley; SriniVas R Sadda; Zhihong Jewel Hu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):293.

ARVO Annual Meeting Abstract June 2023

Mechanical deformation of the human optic nerve with manometric IOP elevation

Christopher A Girkin; Mary Anne Garner; Mark E. Clark; Meredith Hubbard; Udayakumar Karuppanan; Gianfranco Bianco; Massimo Antonio Fazio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1313.

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Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

Robotic Spectral-domain versus Swept-source OCT in the association between OCT-Angiography metrics and glaucoma severity.

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Probing Deposit-Driven Age-Related Macular Degeneration Via Thicknesses of Outer Retinal Bands and Choroid: ALSTAR2 Baseline

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

Potential Structural Biomarkers in 3D Images Validated by the First Functional Biomarker for Early Age-Related Macular Degeneration – ALSTAR2 Baseline

Displacement of the Lamina Cribrosa With Acute Intraocular Pressure Increase in Brain-Dead Organ Donors

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

Anatomic Correlates of Microperimetric Sensitivity in Early (e-AMD) and Intermediate Age-Related Macular Degeneration (i-AMD): ALSTAR2 Baseline Cohort

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Antidepressant medication use is associated with impaired rod-mediated visual functions in normal aging and early and intermediate AMD: ALSTAR2 baseline

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

Relationship between Delayed RMDA and the Ellipsoid and Interdigitation Zones in Age-related Macular Degeneration (AMD): ALSTAR2 baseline

Mechanical deformation of the human optic nerve with manometric IOP elevation

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