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Retina August 2024

Optical Assessment of Photoreceptor Function Over the Macula

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Shuibin Ni; Shanjida Khan; Alfonso Jiménez-Villar; Mark E. Pennesi; David Huang; Yifan Jian; Siyu Chen
TAGS: diagnostic imaging, macula lutea, optics, photoreceptors, retinal cone
Trans. Vis. Sci. Tech.. 2024; 13(8):41. https://doi.org/10.1167/tvst.13.8.41

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2024

Method of Applying Deep Learning Model (DLM) Trained on OCT Images of Lower Axial Resolution to Images of Higher Axial Resolution without Model Retraining for Retinal Layer Segmentation

Yi-Zhong Wang; Mark E. Pennesi; Siyu Chen; David G. Birch

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB0013.

ARVO Imaging in the Eye Conference Abstract July 2024

Ultrahigh-speed swept-source optical coherence tomography for macular optoretinography

Shuibin Ni; Shanjida Khan; Alfonso Jiménez-Villar; Mark E. Pennesi; Steven T. Bailey; David Huang; Yifan Jian; Siyu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PP0023.

Retina June 2024

Perimacular Atrophy Following Voretigene Neparvovec-Rzyl Treatment in the Setting of Previous Contralateral Eye Treatment With a Different Viral Vector

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Cristy A. Ku; Austin D. Igelman; Samuel J. Huang; Steven T. Bailey; Andreas K. Lauer; Jacque L. Duncan; Richard G. Weleber; Paul Yang; Mark E. Pennesi
TAGS: atrophy, chorioretinal atrophy, eye, genes, viral vector, voretigene neparvovec, visual fields
Trans. Vis. Sci. Tech.. 2024; 13(6):11. https://doi.org/10.1167/tvst.13.6.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Six-year results of a Phase I/IIa gene therapy trial in patients with Usher Syndrome Type-1B (USH1B)

Maria Parker; Paul Yang; Dongseok Choi; Saddek Mohand-Said; Shobana Aravind; Ambar Faridi; Elvira Chegarnov; Charles Butler; Pierre-Olivier Barale; Andreas K Lauer; Tim Stout; David Wilson; Richard Weleber; Mark E Pennesi; Jose Alain Sahel; Isabelle S Audo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5327.

ARVO Annual Meeting Abstract June 2024

Developing an in vitro human USH1B model to study retinal disease features

Jana M Giaquinto; Molly Marra; Paul Yang; Mark E Pennesi; Kathleen R Chirco

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1574.

ARVO Annual Meeting Abstract June 2024

Adaptive optics (AO) retinal imaging delineates retinal changes in patients at all ETDRS stages of diabetic macular ischemia, undetectable by other structural and functional imaging in mild to moderate ischemia.

Nick Muthiah MD PhD; Angelos Kalitzeos; Travis Smith; Mark E Pennesi; Kunal K Dansingani; Peter Coffey; Lyndon da Cruz; Michel Michaelides

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5929.

ARVO Annual Meeting Abstract June 2024

Characterization of Flavimaculatus-Like Phenotype in PRPH2 associated Inherited Retinal Disease

Shaden Yassin; Naomi Wagner; Paripoorna Sharma; Evan Walker; Fritz Gerald Paguiligan Kalaw; Thiago DeOliveira; Katherine Andersen; Molly Marra; Lesley Everett; Paul Yang; Mark E Pennesi; Shyamanga Borooah

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD74.

ARVO Annual Meeting Abstract June 2024

Phenotypic Spectrum of Retinal Degeneration in X-Linked PRPS1 -Related Retinopathy

Ogul Uner; Radwa Elsharawi; Margaret Reynolds; Giacomo Bacci; Sara Bargiacchi; Fred Chen; Nieraj Jain; Rachael C Heath Jeffery; Mariana Matioli de Palma; Juliana M F Sallum; Mariam Torres Soto; Kaylie D Webb-Jones; Paul Yang; Mark E Pennesi; Lesley Everett

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1702.

ARVO Annual Meeting Abstract June 2024

Establishing a gene editing strategy for BBS7 using human retinal organoids

Kathleen R Chirco; Jana M Giaquinto; Molly Marra; Paul Yang; Mark E Pennesi; Martha Neuringer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1555.

ARVO Annual Meeting Abstract June 2024

Wide-Field Swept-source structural OCT and OCT Angiography in Inherited Retinal Dystrophies

Xiao Zhou; Nida Wongchaisuwat; Guangru Ben Liang; Tristan T Hormel; Lesley Everett; Paul Yang; Mark E Pennesi; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5495.

ARVO Annual Meeting Abstract June 2024

LAMA1 associated retinopathy: a case series

Andrew Lamborn; Emma Bedoukian; Arif O. Khan; Fernanda Belga Ottoni Porto; Molly Marra; Paul Yang; Mark E Pennesi; Lesley Everett

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3463.

ARVO Annual Meeting Abstract June 2024

Generating Models of PRPH2 -associated retinal dystrophy

Renee Christine Ryals; Nadia Moore; Lauren Renner; Jana M Giaquinto; Molly Marra; Hannah Woolard; Paul Yang; Mark E Pennesi; Samuel Peterson; Besty Ferguson; Martha Neuringer; Kathleen R Chirco

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):817.

ARVO Annual Meeting Abstract June 2024

Inhibition of Inosine Monophosphate Dehydrogenase (IMPDH) Mitigates Guanine Nucleotide Dysregulation in rd10 Mice

Paul Yang; Alexander Hurt; Luke Fraley; Catherine W Morgans; Mark E Pennesi; Robert Duvoisin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1465.

ARVO Annual Meeting Abstract June 2024

Longitudinal imaging of the parafoveal cone mosaic in congenital achromatopsia

Nickolas Chen; Katie M Litts; Danica Nikezic; Christopher S Langlo; Brian P Higgins; Byron L Lam; Fred Collison; Mark E Pennesi; Christine Nichols Kay; Sergey Tarima; Joseph Carroll

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1428.

ARVO Annual Meeting Abstract June 2024

Photoreceptor structure following gene therapy in CNGA3 -mediated Achromatopsia: adaptive optics imaging results from a Phase 1/2 dose escalation clinical trial for AGTC-402 (rAAV2tYF-PR1.7-hCNGA3)

Yu You Jiang; Peiluo Xu; Christine Nichols Kay; Robert Sisk; Rachel M Huckfeldt; Jason Comander; Byron L Lam; Ninel Z. Gregori; Audina Berrocal; Mark E Pennesi; Andreas K Lauer; Amy Christenson; Nadia K Waheed; Jessica Ijams Wolfing Morgan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3289.

ARVO Annual Meeting Abstract June 2024

Using Machine Learning to Assess the Pathogenicity of Small In-frame Indels in Inherited Retinal Disease

David Eldon Rauch; Meng Wang; Hafiz Muhammad Jafar Hussain; Daniel Christopher Brock; Yumei Li; Molly Marra; Mark E Pennesi; Paul Yang; Lesley Everett; Irma Lopez; Edward Ryan Collantes; Joanne Bolinao; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4688.

ARVO Annual Meeting Abstract June 2024

Comparative Analysis of In-Silico Tools in Identifying Pathogenic Variants in Dominant Inherited Retinal Diseases

Daniel Christopher Brock; Meng Wang; Hafiz Muhammad Jafar Hussain; David Rauch; Molly Marra; Mark E Pennesi; Paul Yang; Lesley Everett; Yumei Li; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4657.

ARVO Annual Meeting Abstract June 2024

Gene-edited monkey model of Usher 1B: Assessment of gene therapy

Martha Neuringer; Jonathan Stoddard; Rene Reynaga; Junghyun Ryu; Jon D Hennebold; Carol B Hanna; John V Brigande; Hannah Woolard; Andreas K Lauer; David Wilson; Mark E Pennesi; Sanford L Boye; Shannon Elizabeth Boye; Renee Christine Ryals; Trevor J Mcgill; Lauren Renner

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4269.

ARVO Annual Meeting Abstract June 2024

The Effect of Long-term Systemic versus Local Immunosuppression on Electroretinography in Birdshot Chorioretinopathy

Christopher R Rosenberg; Elizabeth White; Aseel Alsamarraie; Sandip Suresh; Wayne Tschetter; Rene Choi; Richard Weleber; James Rosenbaum; Justine R Smith; Phoebe Lin; Mark E Pennesi; Eric B Suhler; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5874.

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Optical Assessment of Photoreceptor Function Over the Macula

Method of Applying Deep Learning Model (DLM) Trained on OCT Images of Lower Axial Resolution to Images of Higher Axial Resolution without Model Retraining for Retinal Layer Segmentation

Ultrahigh-speed swept-source optical coherence tomography for macular optoretinography

Perimacular Atrophy Following Voretigene Neparvovec-Rzyl Treatment in the Setting of Previous Contralateral Eye Treatment With a Different Viral Vector

Six-year results of a Phase I/IIa gene therapy trial in patients with Usher Syndrome Type-1B (USH1B)

Developing an in vitro human USH1B model to study retinal disease features

Adaptive optics (AO) retinal imaging delineates retinal changes in patients at all ETDRS stages of diabetic macular ischemia, undetectable by other structural and functional imaging in mild to moderate ischemia.

Characterization of Flavimaculatus-Like Phenotype in PRPH2 associated Inherited Retinal Disease

Phenotypic Spectrum of Retinal Degeneration in X-Linked PRPS1 -Related Retinopathy

Establishing a gene editing strategy for BBS7 using human retinal organoids

Wide-Field Swept-source structural OCT and OCT Angiography in Inherited Retinal Dystrophies

LAMA1 associated retinopathy: a case series

Generating Models of PRPH2 -associated retinal dystrophy

Inhibition of Inosine Monophosphate Dehydrogenase (IMPDH) Mitigates Guanine Nucleotide Dysregulation in rd10 Mice

Longitudinal imaging of the parafoveal cone mosaic in congenital achromatopsia

Photoreceptor structure following gene therapy in CNGA3 -mediated Achromatopsia: adaptive optics imaging results from a Phase 1/2 dose escalation clinical trial for AGTC-402 (rAAV2tYF-PR1.7-hCNGA3)

Using Machine Learning to Assess the Pathogenicity of Small In-frame Indels in Inherited Retinal Disease

Comparative Analysis of In-Silico Tools in Identifying Pathogenic Variants in Dominant Inherited Retinal Diseases

Gene-edited monkey model of Usher 1B: Assessment of gene therapy

The Effect of Long-term Systemic versus Local Immunosuppression on Electroretinography in Birdshot Chorioretinopathy

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