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Retina October 2024

Endpoints and Design for Clinical Trials in USH2A -Related Retinal Degeneration: Results and Recommendations From the RUSH2A Natural History Study

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Maureen G. Maguire; David G. Birch; Jacque L. Duncan; Allison R. Ayala; Lauren N. Ayton; Janet K. Cheetham; Peiyao Cheng; Todd A. Durham; Frederick L. Ferris, III; Carel B. Hoyng; Rachel M. Huckfeldt; Glenn J. Jaffe; Christine Kay; Eleonora M. Lad; Bart P. Leroy; Wendi Liang; Lee S. McDaniel; Michele Melia; Michel Michaelides; Mark E. Pennesi; José-Alain Sahel; Lassana Samarakoon; on behalf of the REDI Working Group and the Foundation Fighting Blindness Clinical Consortium Investigator Group
TAGS: cohort studies, eye, natural history, outcome measures, retinal degeneration, sample size, surrogate endpoints, vision, united states food and drug administration, perimetry
Trans. Vis. Sci. Tech.. 2024; 13(10):15. https://doi.org/10.1167/tvst.13.10.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Bilamellar Tarsal Rotation (BLTR) vs Posterior Lamellar Tarsal Rotation (PLTR) for Trachomatous Trichiasis (TT)

John H Kempen; Yineng Chen; Aida Abashawl; Ahlam Awad Mohammed; Sarity Dodson; Wondu Alemayehu; Alemu Gemechu; Dereje Adugna; Aemero Abateneh; Tony Succar; Vatinee Y Bunya; Kathy McWilliams; Maureen G Maguire; Matthew Burton; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2813.

ARVO Annual Meeting Abstract June 2023

Multimodal Identification and Quantification of Subretinal Fibrosis in Eyes with Neovascular AMD in CATT

Grace E Nipp; Sandra S Stinnett; Stephanie J Chiu; Gui-Shuang Ying; Ebenezer Daniel; Maureen G Maguire; Dilraj Singh Grewal; Glenn J Jaffe

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2384.

Cornea January 2023

Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study

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Jack V. Greiner; Gui-shuang Ying; Maxwell Pistilli; Maureen G. Maguire; Penny A. Asbell; for the Dry Eye Assessment and Management (DREAM) Study Research Group
TAGS: dreams, dry eye syndromes, osmolar concentration, signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):5. https://doi.org/10.1167/iovs.64.1.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Visual acuity and full-field stimulus thresholds (FST) over 2 years in the RUSH2A study: annual rates of change from mixed effects modeling

Peiyao Cheng; David G Birch; Jacque L Duncan; Frederick L Ferris; Maureen G Maguire; Allison R. Ayala; Janet K Cheetham; Todd Durham; Abigail T Fahim; Rachel M Huckfeldt; Michel Michaelides; Mark E Pennesi; Jose Alain Sahel; Katarina Stingl; Ajoy Vincent; Christina Y Weng

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4480 – F0267.

ARVO Annual Meeting Abstract June 2021

A multimodal deep learning (DL) model to predict visual acuity response in the CATT study

Jelena Novosel; Neha Anegondi; Jian Dai; Ebenezer Daniel; Glenn J Jaffe; Maureen G Maguire; Jeffrey R Willis

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):81.

ARVO Annual Meeting Abstract June 2021

Auditory and olfactory findings from the Rate of Progression of USH2A -related Retinal Degeneration (RUSH2A) study

Alessandro Iannaccone; Carmen C. Brewer; Peiyao Cheng; Jacque L Duncan; Maureen G Maguire; Isabelle Audo; Allison Ayala; Paul S Bernstein; Gavin M. bidelman; Janet K Cheetham; Richard L. Doty; Todd Durham; Robert B Hufnagel; Mark H. Myers; Wadih M Zein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1537.

ARVO Annual Meeting Abstract June 2021

Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)

Jason Quan College; Maxwell Pistilli; Ebenezer Daniel; Maureen G Maguire; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):334.

ARVO Annual Meeting Abstract June 2021

Effect of teprotumumab on intraocular pressure in thyroid-associated ophthalmopathy

Modupe O Adetunji; Brian Jonathan Nguyen; Elana Meer; Brady Kwong; Brendan McGeehan; Maureen G Maguire; Madhura Tamhankar; César A Briceño

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3327.

ARVO Annual Meeting Abstract June 2021

Association of oral statin use with dry eye symptoms and signs in the DRy Eye Assessment and Management (DREAM © ) Study

Yinxi Yu; Maureen G Maguire; Neeta Roy; Penny A Asbell; Kimberley Yu; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1227.

ARVO Annual Meeting Abstract June 2021

Association between depression and severity of dry eye symptoms and signs among patients in the Dry Eye Assessment and Management (DREAM) Study

Yi Zhou; Maureen G Maguire; James Murrough; Yinxi Yu; Neeta Roy; Rony R Sayegh; Penny A Asbell; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1226.

ARVO Annual Meeting Abstract June 2021

Systemic conditions associated with the severity of dry eye signs and symptoms in the Dry Eye Assessment and Management (DREAM) Study

Kimberley Yu; Vatinee Y Bunya; Maureen G Maguire; Penny A Asbell; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1223.

ARVO Annual Meeting Abstract June 2021

Tutorial on Biostatistics: Receiver-Operating Characteristic (ROC) Analysis for Correlated Eye Data

Bernard Rosner; Gui-Shuang Ying; Maureen G Maguire; Robert Glynn

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):175.

Articles March 2021

Effect of Initial Aflibercept, Laser, or Observation on Low-Contrast Visual Acuity in Eyes With Diabetic Macular Edema and Good Vision: Ancillary Study Within a Randomized Clinical Trial

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Wesley T. Beaulieu; Adam R. Glassman; Carl W. Baker; Maureen G. Maguire; Chris A. Johnson; Michele Melia; Jennifer K. Sun; for the DRCR Retina Network
TAGS: aflibercept, clinical trials, diabetic macular edema, eye, lasers, vision, visual acuity
Trans. Vis. Sci. Tech.. 2021; 10(3):3. https://doi.org/10.1167/tvst.10.3.3

Articles October 2020

Repeatability and Reproducibility of Axial and Lateral Measurements on Handheld Optical Coherence Tomography Systems Compared with Tabletop System

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Xi Chen; Vincent Tai; Brendan McGeehan; Gui-Shuang Ying; Christian Viehland; Ryan Imperio; Katrina P. Winter; William Raynor; Du Tran-Viet; Shwetha Mangalesh; Maureen G. Maguire; Cynthia A. Toth; for the BabySTEPS Group
TAGS: mobile devices, optical coherence tomography, retinal nerve fiber layer, fovea centralis, adult, eye
Trans. Vis. Sci. Tech.. 2020; 9(11):25. https://doi.org/10.1167/tvst.9.11.25

Includes: Supplemental Content

Articles October 2020

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

PDF

David G. Birch; Peiyao Cheng; Jacque L. Duncan; Allison R. Ayala; Maureen G. Maguire; Isabelle Audo; Janet K. Cheetham; Todd A. Durham; Abigail T. Fahim; Frederick L. Ferris, III; Elise Heon; Rachel M. Huckfeldt; Alessandro Iannaccone; Naheed W. Khan; Eleonora M. Lad; Michel Michaelides; Mark E. Pennesi; Katarina Stingl; Ajoy Vincent; Christina Y. Weng; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: electroretinography, visual acuity
Trans. Vis. Sci. Tech.. 2020; 9(11):9. https://doi.org/10.1167/tvst.9.11.9

Includes: Supplemental Content

Focus on Data September 2020

Calculating Sensitivity, Specificity, and Predictive Values for Correlated Eye Data

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Gui-Shuang Ying; Maureen G. Maguire; Robert J. Glynn; Bernard Rosner
TAGS: eye, sensitivity and specificity
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):29. https://doi.org/10.1167/iovs.61.11.29

Includes: Supplemental Content

Editorial June 2020

New Section on Using Data from Vision Research

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Maureen G. Maguire
TAGS: vision research
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):26. https://doi.org/10.1167/iovs.61.6.26

Focus on Data June 2020

Assessing Intereye Symmetry and Its Implications for Study Design

PDF

Maureen G. Maguire
TAGS: eye, research design
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):27. https://doi.org/10.1167/iovs.61.6.27

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2020

Visual Image Quality Impacts Circadian Rhythm-Related Gene Expression in Retina and in Choroid: A Potential Mechanism for Ametropias

PDF

Richard A. Stone; Wenjie Wei; Shanta Sarfare; Brendan McGeehan; K. Cameron Engelhart; Tejvir S. Khurana; Maureen G. Maguire; P. Michael Iuvone; Debora L. Nickla
TAGS: choroid, circadian clocks, eye, gene expression, genes, image quality, lens (device), lens, crystalline, refractive errors, retina
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):13. https://doi.org/10.1167/iovs.61.5.13

Includes: Supplemental Content

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Endpoints and Design for Clinical Trials in USH2A -Related Retinal Degeneration: Results and Recommendations From the RUSH2A Natural History Study

Bilamellar Tarsal Rotation (BLTR) vs Posterior Lamellar Tarsal Rotation (PLTR) for Trachomatous Trichiasis (TT)

Multimodal Identification and Quantification of Subretinal Fibrosis in Eyes with Neovascular AMD in CATT

Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study

Visual acuity and full-field stimulus thresholds (FST) over 2 years in the RUSH2A study: annual rates of change from mixed effects modeling

A multimodal deep learning (DL) model to predict visual acuity response in the CATT study

Auditory and olfactory findings from the Rate of Progression of USH2A -related Retinal Degeneration (RUSH2A) study

Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)

Effect of teprotumumab on intraocular pressure in thyroid-associated ophthalmopathy

Association of oral statin use with dry eye symptoms and signs in the DRy Eye Assessment and Management (DREAM © ) Study

Association between depression and severity of dry eye symptoms and signs among patients in the Dry Eye Assessment and Management (DREAM) Study

Systemic conditions associated with the severity of dry eye signs and symptoms in the Dry Eye Assessment and Management (DREAM) Study

Tutorial on Biostatistics: Receiver-Operating Characteristic (ROC) Analysis for Correlated Eye Data

Effect of Initial Aflibercept, Laser, or Observation on Low-Contrast Visual Acuity in Eyes With Diabetic Macular Edema and Good Vision: Ancillary Study Within a Randomized Clinical Trial

Repeatability and Reproducibility of Axial and Lateral Measurements on Handheld Optical Coherence Tomography Systems Compared with Tabletop System

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

Calculating Sensitivity, Specificity, and Predictive Values for Correlated Eye Data

New Section on Using Data from Vision Research

Assessing Intereye Symmetry and Its Implications for Study Design

Visual Image Quality Impacts Circadian Rhythm-Related Gene Expression in Retina and in Choroid: A Potential Mechanism for Ametropias

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