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ARVO Annual Meeting Abstract June 2024

Comparison of protein biomarker profile in tears from eyes of healthy subjects and dry eye disease patients using novel Olink® Proteomics Technology

Mitalee Tamhane; Scott Gladstein; Vivian Zhao; Lisa Borbridge; Katherine S Held; Xin Huang; Jie Shen; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6565.

ARVO Annual Meeting Abstract June 2022

Plasma pharmacokinetics of pilocarpine in participants administered VUITY TM (pilocarpine HCl ophthalmic solution) 1.25%

Jennifer Seal; Lisa M. Borbridge; David Wirta; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1808 – F0424.

ARVO Annual Meeting Abstract June 2021

A Minipump Continuous Drug Infusion Dog Model System to Identify Candidate Drugs and Drug Delivery Rates for Intracameral IOP-lowering Implants

Jie Shen; Michael R Robinson; James Burke; Tim T Lam; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2753.

ARVO Annual Meeting Abstract June 2020

Pharmacokinetics of Brimonidine DDS Implants in Preclinical and Phase II Studies – Implications of Formulation Change from Generation 1 to Generation 2

Mitalee Tamhane; Ashutosh A Kulkarni; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1038.

Articles March 2020

Nonclinical Pharmacokinetic and Pharmacodynamic Assessment of Bimatoprost Following a Single Intracameral Injection of Sustained-Release Implants

PDF

Jie Shen; Michael R. Robinson; Craig Struble; Mayssa Attar
TAGS: bimatoprost, implants, injections, intraocular pressure, pharmacodynamics
Trans. Vis. Sci. Tech.. 2020; 9(4):20. https://doi.org/10.1167/tvst.9.4.20

ARVO Annual Meeting Abstract July 2018

Simulation of Ocular Drug Distribution Following Zero Order Release of Intravitreally Dosed Bevacizumab Using 3D Computational Fluid Dynamic Model

Jie Shen; Mohammad Kazemi; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):228.

ARVO Annual Meeting Abstract July 2018

Pegylation of Abicipar Increases Vitreal Half-Life, Supporting a Potential for up to 3 Month Duration of Action in the Clinic

Jennifer Seal; Savira Ekawardhani; Anja Schlegel; Michael T Stumpp; H. Kaspar Binz; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):244.

ARVO Annual Meeting Abstract September 2016

Multiplicities of Lacrimal Gland Disease Phenotypes

Austin K Mircheff; Yanru Wang; Joel E Schechter; Meng Li; Warren Tong; Mayssa Attar; Murty Chengalvala; Joe Harmuth; Jeffery J Prusakiewicz

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):392.

ARVO Annual Meeting Abstract September 2016

Intracameral Administration of a Sustained Release Bimatoprost Implant Efficiently Delivers Bimatoprost to Target Tissue Reducing Risk of Topical Prostaglandin Analog- Associated Adverse Events

Jennifer Seal; Shamira Perera; Michael Coote; Michael R Robinson; Patrick M Hughes; Alazar N Ghebremeskel; James A Burke; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3022.

ARVO Annual Meeting Abstract September 2016

Comparative Ocular Distribution of 14 C-Latanoprost Following a Single Intracameral or Repeated Topical Ocular Dose in Dogs

Jie Shen; Michael R Robinson; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5640.

ARVO Annual Meeting Abstract September 2016

Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Rabbits and Monkeys and It’s Application in Selection of Dosing Frequency in Human Clinical Trials

Mitalee Tamhane; Michael R Robinson; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2154.

ARVO Annual Meeting Abstract June 2015

Evaluation of vitreous half-life and ocular distribution in rats, rabbits and monkeys after intravitreal administration of a novel biologic

Mitalee Tamhane; Swati Gupta; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):221.

ARVO Annual Meeting Abstract June 2015

Methods for an Enhanced 3D Interpretation of Autoradiographic Ocular Drug Distribution Data

Julie Elizabeth Whitcomb; Susan S Lee; Michael Robinson; Jie Shen; Elizabeth Spencer; Meagan Krueger; Harvey Pollack; Rex Moats; Yang Tang; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4120.

ARVO Annual Meeting Abstract June 2015

The effect of elevated intraocular pressure on convective flow in the vitreous

Susan S Lee; Michael Robinson; Mohammad Kazemi; Anita Nikolova Penkova; Satwindar Singh Sadhal; Mayssa Attar; Julie Elizabeth Whitcomb

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):234.

ARVO Annual Meeting Abstract April 2014

The Rate and Extent of Cyclosporine Absorption is Formulation and Tissue Dependent following Topical Ophthalmic Administration

Mayssa Attar; Richard Graham; Lisa Borbridge; Sesha Neervannan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):457.

ARVO Annual Meeting Abstract April 2014

Exploring Drug Distribution via the Suprachoroidal Space in a Human and Rabbit Eye Using Computational Modeling

Julie Elizabeth Whitcomb; Mohammad R Kazemi; James A Burke; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5250.

ARVO Annual Meeting Abstract June 2013

Cross-Species and Cross-Age Comparison of Esterase Mediated Metabolism in Vitreous Humor: Human versus Rabbit, Dog and Monkey

Mayssa Attar; Jie Shen; Moon Kim; Que-Chau Radojicic

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5404.

ARVO Annual Meeting Abstract April 2011

Modulation of Glucocorticoid Receptor Gene Expression: Potential Role in the Pharmacokinetic/Pharmacodynamic Relationship of Ozurdex

Mayssa Attar; Moon Kim; George Sachs; David Scott; Craig B. Struble; Devin F. Welty

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5643.

Retina January 2011

Pharmacokinetics and Pharmacodynamics of a Sustained-Release Dexamethasone Intravitreal Implant

PDF

Joan-En Chang-Lin; Mayssa Attar; Andrew A. Acheampong; Michael R. Robinson; Scott M. Whitcup; Baruch D. Kuppermann; Devin Welty
TAGS: dexamethasone, implants, intravitreal implants, pharmacodynamics, pharmacokinetics, retina, vitreous body, eye, plasma, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2011; 52(1):80-86. https://doi.org/10.1167/iovs.10-5285

Physiology and Pharmacology December 2005

Cytochrome P450 3A Expression and Activity in the Rabbit Lacrimal Gland: Glucocorticoid Modulation and the Impact on Androgen Metabolism

PDF

Mayssa Attar; Kah-Hiing John Ling; Diane D.-S. Tang-Liu; Nouri Neamati; Vincent H. L. Lee
TAGS: androgens, cyp3a protein, human, cytochrome p450, dexamethasone, lacrimal gland, metabolism, oryctolagus cuniculus, testosterone, glucocorticoids, microsomes
Invest. Ophthalmol. Vis. Sci.. 2005; 46(12):4697-4706. https://doi.org/10.1167/iovs.05-0139

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Comparison of protein biomarker profile in tears from eyes of healthy subjects and dry eye disease patients using novel Olink® Proteomics Technology

Plasma pharmacokinetics of pilocarpine in participants administered VUITY TM (pilocarpine HCl ophthalmic solution) 1.25%

A Minipump Continuous Drug Infusion Dog Model System to Identify Candidate Drugs and Drug Delivery Rates for Intracameral IOP-lowering Implants

Pharmacokinetics of Brimonidine DDS Implants in Preclinical and Phase II Studies – Implications of Formulation Change from Generation 1 to Generation 2

Nonclinical Pharmacokinetic and Pharmacodynamic Assessment of Bimatoprost Following a Single Intracameral Injection of Sustained-Release Implants

Simulation of Ocular Drug Distribution Following Zero Order Release of Intravitreally Dosed Bevacizumab Using 3D Computational Fluid Dynamic Model

Pegylation of Abicipar Increases Vitreal Half-Life, Supporting a Potential for up to 3 Month Duration of Action in the Clinic

Multiplicities of Lacrimal Gland Disease Phenotypes

Intracameral Administration of a Sustained Release Bimatoprost Implant Efficiently Delivers Bimatoprost to Target Tissue Reducing Risk of Topical Prostaglandin Analog- Associated Adverse Events

Comparative Ocular Distribution of 14 C-Latanoprost Following a Single Intracameral or Repeated Topical Ocular Dose in Dogs

Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Rabbits and Monkeys and It’s Application in Selection of Dosing Frequency in Human Clinical Trials

Evaluation of vitreous half-life and ocular distribution in rats, rabbits and monkeys after intravitreal administration of a novel biologic

Methods for an Enhanced 3D Interpretation of Autoradiographic Ocular Drug Distribution Data

The effect of elevated intraocular pressure on convective flow in the vitreous

The Rate and Extent of Cyclosporine Absorption is Formulation and Tissue Dependent following Topical Ophthalmic Administration

Exploring Drug Distribution via the Suprachoroidal Space in a Human and Rabbit Eye Using Computational Modeling

Cross-Species and Cross-Age Comparison of Esterase Mediated Metabolism in Vitreous Humor: Human versus Rabbit, Dog and Monkey

Modulation of Glucocorticoid Receptor Gene Expression: Potential Role in the Pharmacokinetic/Pharmacodynamic Relationship of Ozurdex

Pharmacokinetics and Pharmacodynamics of a Sustained-Release Dexamethasone Intravitreal Implant

Cytochrome P450 3A Expression and Activity in the Rabbit Lacrimal Gland: Glucocorticoid Modulation and the Impact on Androgen Metabolism

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