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Perspective December 2024

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

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Ted S. Acott; Michael P. Fautsch; Weiming Mao; C. Ross Ethier; Alex S. Huang; Mary J. Kelley; Mini Aga; Sanjoy K. Bhattacharya; Terete Borras; Diane Bovenkamp; Uttio Roy Chowdhury; Abbot F. Clark; Mohammed I. Dibas; Yiqin Du; Michael H. Elliott; Jennifer A. Faralli; Haiyan Gong; Samuel Herberg; Murray A. Johnstone; Paul L. Kaufman; Kate E. Keller; Ruth A. Kelly; David Krizaj; Markus H. Kuehn; Hoi Lam Li; Raquel Lieberman; Shan C. Lin; Yutao Liu; Fiona S. McDonnell; Colleen M. McDowell; Gillian J. McLellan; Philip Mzyk; Kayarat Saidas Nair; Darryl R. Overby; Donna M. Peters; VijayKrishna Raghunathan; Ponugoti Vasantha Rao; Gavin W. Roddy; Najam A. Sharif; Myoung Sup Shim; Yang Sun; Benjamin R. Thomson; Carol B. Toris; Colin E. Willoughby; Hao F. Zhang; Thomas F. Freddo; Rudolf Fuchshofer; Kamisha R. Hill; Alireza Karimi; Krishnakumar Kizhatil; Casey C. Kopcyznski; Paloma Liton; Gaurang Patel; Michael Peng; Padmanabhan P. Pattabiraman; Ganesh Prasanna; Ester Reina-Torres; E. Griffen Samples; John R. Samples; Cynthia L. Steel; Clemens A. Strohmaier; Preeti Subramanian; Chenna Kesavulu Sugali; Joseph van Batenburg-Sherwood; Cydney Wong; Hannah Youngblood; Gulab S. Zode; Elizabeth White; W. Daniel Stamer
TAGS: body tissue, eye, fluid flow, intraocular pressure, perfusion, regulation, organ culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):32. https://doi.org/10.1167/iovs.65.14.32

Retina October 2024

Multi-Characteristic Opsin Therapy to Functionalize Retina, Attenuate Retinal Degeneration, and Restore Vision in Mouse Models of Retinitis Pigmentosa

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Subrata Batabyal; Sanghoon Kim; Michael Carlson; Darryl Narcisse; Kissaou Tchedre; Adnan Dibas; Najam A. Sharif; Samarendra Mohanty
TAGS: intravitreal injections, mice, retina, retinal degeneration, vision, injections, tissue degeneration
Trans. Vis. Sci. Tech.. 2024; 13(10):25. https://doi.org/10.1167/tvst.13.10.25

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Physiology and Pharmacology March 2011

Effect of Elevated Intracellular cAMP Levels on Actomyosin Contraction in Bovine Trabecular Meshwork Cells

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Charanya Ramachandran; Rajkumar V. Patil; Najam A. Sharif; Sangly P. Srinivas
TAGS: actomyosin, cyclic amp, rhoa gtp-binding protein
Invest. Ophthalmol. Vis. Sci.. 2011; 52(3):1474-1485. https://doi.org/10.1167/iovs.10-6241

Physiology and Pharmacology November 2010

Endogenous Regulation of Human Schlemm's Canal Cell Volume by Nitric Oxide Signaling

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Dorette Z. Ellis; Najam A. Sharif; William M. Dismuke
TAGS: cell volume, nitric oxide, schlemm's canal, deet, signal transduction, regulation
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5817-5824. https://doi.org/10.1167/iovs.09-5072

Physiology and Pharmacology July 2009

Human Trabecular Meshwork Cell Volume Decrease by NO-Independent Soluble Guanylate Cyclase Activators YC-1 and BAY-58-2667 Involves the BK Ca Ion Channel

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William M. Dismuke; Najam A. Sharif; Dorette Z. Ellis
TAGS: cell volume, cyclic gmp, ion channels, soluble guanylyl cyclase, transcriptional activation, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2009; 50(7):3353-3359. https://doi.org/10.1167/iovs.08-3127

Physiology and Pharmacology September 2006

Human Trabecular Meshwork Cells Express Functional Serotonin-2A (5HT 2A ) Receptors: Role in IOP Reduction

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Najam A. Sharif; Curtis R. Kelly; Marsha McLaughlin
TAGS: agonists, intraocular pressure, serotonin, trabecular meshwork, donors, antagonists, eye, ocular hypertension
Invest. Ophthalmol. Vis. Sci.. 2006; 47(9):4001-4010. https://doi.org/10.1167/iovs.06-0062

Physiology and Pharmacology November 2003

Pharmacological Characterization of a Serotonin Receptor (5-HT 7 ) Stimulating cAMP Production in Human Corneal Epithelial Cells

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Julie Y. Crider; Gary W. Williams; Colene D. Drace; Parvaneh Katoli; Michelle Senchyna; Najam A. Sharif
TAGS: corneal epithelial cells, cyclic amp, pharmacology, serotonin, serotonin receptor, antagonists
Invest. Ophthalmol. Vis. Sci.. 2003; 44(11):4837-4844. https://doi.org/10.1167/iovs.02-1292

Physiology and Pharmacology February 2003

Human Trabecular Meshwork Cell Responses Induced by Bimatoprost, Travoprost, Unoprostone, and other FP Prostaglandin Receptor Agonist Analogues

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Najam A. Sharif; Curtis R. Kelly; Julie Y. Crider
TAGS: agonists, bimatoprost, prostaglandin receptor, trabecular meshwork, travoprost, unoprostone isopropyl
Invest. Ophthalmol. Vis. Sci.. 2003; 44(2):715-721. https://doi.org/10.1167/iovs.02-0323

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Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

Multi-Characteristic Opsin Therapy to Functionalize Retina, Attenuate Retinal Degeneration, and Restore Vision in Mouse Models of Retinitis Pigmentosa

Effect of Elevated Intracellular cAMP Levels on Actomyosin Contraction in Bovine Trabecular Meshwork Cells

Endogenous Regulation of Human Schlemm's Canal Cell Volume by Nitric Oxide Signaling

Human Trabecular Meshwork Cell Volume Decrease by NO-Independent Soluble Guanylate Cyclase Activators YC-1 and BAY-58-2667 Involves the BK Ca Ion Channel

Human Trabecular Meshwork Cells Express Functional Serotonin-2A (5HT 2A ) Receptors: Role in IOP Reduction

Pharmacological Characterization of a Serotonin Receptor (5-HT 7 ) Stimulating cAMP Production in Human Corneal Epithelial Cells

Human Trabecular Meshwork Cell Responses Induced by Bimatoprost, Travoprost, Unoprostone, and other FP Prostaglandin Receptor Agonist Analogues

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