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ARVO Annual Meeting Abstract June 2024

Mustard gas exposure causes meibomian gland deficiency in rabbit eye in vivo

Ratnakar Tripathi; Nishant R. Sinha; Brenden R Lankau; Maxwell Jeffrey; Prashant R. Sinha; Laila Ayman Suleiman; Payton lujin; Suneel Gupta; Nathan P Hesemann; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):505.

ARVO Annual Meeting Abstract June 2022

Evaluations of localized topical tissue-targeted AAV5-Id3 gene delivery to treat

Suneel Gupta; Nishant Rajiv Sinha; Lynn M Martin; Landon Keele; Nathan P. Hesemann; Prashant Sinha; Elizabeth A Giuliano; Ratnakar Tripathi; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):117 – A0215.

ARVO Annual Meeting Abstract June 2022

Evaluation of delayed/chronic corneal toxicity and clinical manifestations for 4-month after mustard gas exposure to rabbit eyes in vivo

Ratnakar Tripathi; Nishant Rajiv Sinha; Praveen Kumar Balne; Alexandria Hofmann; Sydney L. Green; Laila A Suleaiman; Prashant Sinha; Nathan P Hesemann; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):115 – A0213.

Special Issue August 2021

Long-Term Safety and Tolerability of BMP7 and HGF Gene Overexpression in Rabbit Cornea

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Suneel Gupta; Nishant R. Sinha; Lynn M. Martin; Landon M. Keele; Prashant R. Sinha; Jason T. Rodier; James R. Landreneau; Nathan P. Hesemann; Rajiv R. Mohan
TAGS: cornea, genes, oryctolagus cuniculus, safety, eye, spatial vectors, gene therapy, disease vectors, protein overexpression, body tissue
Trans. Vis. Sci. Tech.. 2021; 10(10):6. https://doi.org/10.1167/tvst.10.10.6

Special Issue August 2021

Six-Month In Vivo Safety Profiling of Topical Ocular AAV5–Decorin Gene Transfer

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Rajiv R. Mohan; Praveen K. Balne; Maryam S. Muayad; Ratnakar Tripathi; Nishant R. Sinha; Suneel Gupta; Jella A. An; Prashant R. Sinha; Nathan P. Hesemann
TAGS: cornea, eye, gene therapy, gene transfer techniques, oryctolagus cuniculus, safety, spatial vectors, genes, disease vectors
Trans. Vis. Sci. Tech.. 2021; 10(10):5. https://doi.org/10.1167/tvst.10.10.5

Articles November 2020

A Novel Topical Ophthalmic Formulation to Mitigate Acute Mustard Gas Keratopathy In Vivo: A Pilot Study

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Ratnakar Tripathi; Praveen K. Balne; Nishant R. Sinha; Lynn M. Martin; Sabeeh Kamil; James R. Landreneau; Suneel Gupta; Jason T. Rodier; Prashant R. Sinha; Nathan P. Hesemann; Alexandria C. Hofmann; Michael K. Fink; Shyam S. Chaurasia; Rajiv R. Mohan

Trans. Vis. Sci. Tech.. 2020; 9(12):6. https://doi.org/10.1167/tvst.9.12.6

ARVO Annual Meeting Abstract July 2019

Topical ophthalmic formulation to counteract sulfur mustardinduced corneal damage

Nishant Sinha; Ratnakar Tripathi; Suneel Gupta; Praveen Balne; Nathan P. Hesemann; Jason Rodier; Elizabeth A Giuliano; Prashant R. Sinha; Lynn M Martin; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4672.

ARVO Annual Meeting Abstract July 2019

GCLC nanomedicine for mitigation of Acrolein toxicity in the cornea

Prashant R. Sinha; Suneel Gupta; Praveen Balne; Ratnakar Tripathi; Elizabeth A Giuliano; Jason Rodier; Nathan P. Hesemann; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4673.

ARVO Annual Meeting Abstract July 2019

Id3 gene over-expression in corneal stromal fibroblasts blocks TGFβ-driven fibrosis in an in vitro model

Mikayla Fraunfelder; Suneel Gupta; Michael K. Fink; Praveen Balne; Ratnakar Tripathi; Prashant R. Sinha; Sally Heil; Elizabeth A Giuliano; Nathan P. Hesemann; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4674.

ARVO Annual Meeting Abstract July 2019

KCa3.1 Ion Channel Inhibition Prevents Exuberant Corneal Wound Healing and Ameliorates TGFβ1-induced Corneal Fibrosis

Helena Lam; Suneel Gupta; Ratnakar Tripathi; Praveen Balne; Sally Heil; Nishant Sinha; Nathan P. Hesemann; Jason Rodier; Prashant R. Sinha; Elizabeth A Giuliano; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4689.

ARVO Annual Meeting Abstract July 2019

MyoD gene silencing promotes corneal fibroblast de-differentiation and reverses fibrosis

Rajiv R Mohan; Ratnakar Tripathi; Praveen Balne; Suneel Gupta; Jason Rodier; Sally Heil; Prashant R. Sinha; Nathan P. Hesemann; Arkasubhra Ghosh; Shyam S Chaurasia

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5250.

Cornea February 2018

Novel Combination BMP7 and HGF Gene Therapy Instigates Selective Myofibroblast Apoptosis and Reduces Corneal Haze In Vivo

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Suneel Gupta; Michael K. Fink; Arkasubhra Ghosh; Ratnakar Tripathi; Prashant R. Sinha; Ajay Sharma; Nathan P. Hesemann; Shyam S. Chaurasia; Elizabeth A. Giuliano; Rajiv R. Mohan
TAGS: apoptosis, cornea, corneal opacity, fibrosis, gene therapy, myofibroblasts, genes, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1045-1057. https://doi.org/10.1167/iovs.17-23308

ARVO Annual Meeting Abstract June 2017

Id Genes: Key Regulator of Fibroblast Transdifferentiation to Myofibroblast In The Cornea

Suneel Gupta; Tripathi Ratnakar; govindaraj anumanthan; Michael K Fink; Prashant Rajiv Sinha; Elizabeth A Giuliano; Nathan P Hesemann; Shyam S Chaurasia; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1007.

ARVO Annual Meeting Abstract June 2017

Precision nanomedicine for eliminating corneal fibrosis and restoring vision with HGF-BMP7 gene transfer

Michael K Fink; Suneel Gupta; Ratnakar Tripathi; govindaraj anumanthan; Prashant Rajiv Sinha; Matthew Faubion; Arkasubhra Ghosh; Nathan P Hesemann; Shyam S Chaurasia; Elizabeth A Giuliano; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1175.

ARVO Annual Meeting Abstract June 2017

Blockade of Kca3.1: A Novel Therapeutic Target To Treat TGF-β1 Induced Fibrosis Associated With Glaucoma Filtration Surgery

govindaraj anumanthan; Philip J Wilson; Tripathi Ratnakar; Suneel Gupta; Nathan P Hesemann; Elizabeth A Giuliano; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4949.

ARVO Annual Meeting Abstract June 2017

SIRT1: Expression in the cornea and its role in corneal wound healing

Rajiv R Mohan; govindaraj anumanthan; Tripathi Ratnakar; Suneel Gupta; Michael K Fink; Prashant Rajiv Sinha; Sally D Heil; Shyam S Chaurasia; Elizabeth A Giuliano; Nathan P Hesemann

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):144.

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Mustard gas exposure causes meibomian gland deficiency in rabbit eye in vivo

Evaluations of localized topical tissue-targeted AAV5-Id3 gene delivery to treat

Evaluation of delayed/chronic corneal toxicity and clinical manifestations for 4-month after mustard gas exposure to rabbit eyes in vivo

Long-Term Safety and Tolerability of BMP7 and HGF Gene Overexpression in Rabbit Cornea

Six-Month In Vivo Safety Profiling of Topical Ocular AAV5–Decorin Gene Transfer

A Novel Topical Ophthalmic Formulation to Mitigate Acute Mustard Gas Keratopathy In Vivo: A Pilot Study

Topical ophthalmic formulation to counteract sulfur mustardinduced corneal damage

GCLC nanomedicine for mitigation of Acrolein toxicity in the cornea

Id3 gene over-expression in corneal stromal fibroblasts blocks TGFβ-driven fibrosis in an in vitro model

KCa3.1 Ion Channel Inhibition Prevents Exuberant Corneal Wound Healing and Ameliorates TGFβ1-induced Corneal Fibrosis

MyoD gene silencing promotes corneal fibroblast de-differentiation and reverses fibrosis

Novel Combination BMP7 and HGF Gene Therapy Instigates Selective Myofibroblast Apoptosis and Reduces Corneal Haze In Vivo

Id Genes: Key Regulator of Fibroblast Transdifferentiation to Myofibroblast In The Cornea

Precision nanomedicine for eliminating corneal fibrosis and restoring vision with HGF-BMP7 gene transfer

Blockade of Kca3.1: A Novel Therapeutic Target To Treat TGF-β1 Induced Fibrosis Associated With Glaucoma Filtration Surgery

SIRT1: Expression in the cornea and its role in corneal wound healing

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