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Lens July 2024

Connexin 50 Influences the Physiological Optics of the In Vivo Mouse Lens

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Xingzheng Pan; Eric R. Muir; Caterina Sellitto; Zhao Jiang; Paul J. Donaldson; Thomas W. White
TAGS: lens (device), lens, crystalline, mice, optics, gap junction protein, water, physiological optics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):19. https://doi.org/10.1167/iovs.65.8.19

ARVO Annual Meeting Abstract June 2024

Presbyopia treatment with 1.25% pilocarpine alters free water distribution in the human lens

Alyssa L Lie; Xingzheng Pan; Oscar Lee; Regina Lee; Thomas William White; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6315.

ARVO Annual Meeting Abstract June 2024

Imaging the activation of mechanosensitive signaling pathways in response in changes to zonular tension in different regions of the rat lens

Yadi Chen; Kevin Webb; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1482.

ARVO Annual Meeting Abstract June 2024

Effect of TRPV1 activation on the accommodative changes in monkey crystalline lens shape, power, and stiffness

Bianca Maceo Heilman; Juan Carlos Navia; Heather Ann Durkee; Braulio Carrera Loureiro B Ferreira; Fabrice Manns; Jean-Marie A Parel; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1481.

ARVO Annual Meeting Abstract June 2024

MP20 the forgotten lens membrane protein: old questions new views

Paul J Donaldson; Ju-Wei Liu; Aran Sisley; Angus Grey; Tamir Gonen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3285.

ARVO Annual Meeting Abstract June 2024

Spatial assessment of UV-A exposure on bovine lenses: Towards a new cataract model

Emily MacFarlane; Julie C Lim; Paul J Donaldson; Angus Grey

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5026.

Lens April 2023

Age-Dependent Changes in the Water Content and Optical Power of the In Vivo Mouse Lens Revealed by Multi-Parametric MRI and Optical Modeling

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Xingzheng Pan; Eric R. Muir; Caterina Sellitto; Kehao Wang; Catherine Cheng; Barbara Pierscionek; Paul J. Donaldson; Thomas W. White
TAGS: lens (device), lens, crystalline, mice, optics, water, biological transport, aging, shape
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):24. https://doi.org/10.1167/iovs.64.4.24

ARVO Annual Meeting Abstract June 2022

Small molecule movement in the bovine lens – comparing and contrasting nutrient and pharmaceutical uptake and metabolism with MALDI mass spectrometry

Angus C Grey; George Guo; Kyriakos Varnava; Ali Zahraei; Melody Tang; Nicholas Demarais; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3110.

Lens July 2021

Age-Dependent Changes in Total and Free Water Content of In Vivo Human Lenses Measured by Magnetic Resonance Imaging

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Alyssa L. Lie; Xingzheng Pan; Thomas W. White; Ehsan Vaghefi; Paul J. Donaldson
TAGS: lens, crystalline, magnetic resonance imaging, water, lens (device), aging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):33. https://doi.org/10.1167/iovs.62.9.33

Lens June 2021

Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice

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Renita Maria Martis; Bo Li; Paul James Donaldson; Julie Ching-Hsia Lim
TAGS: cataract, cystine, lens (device), lens, crystalline, mice, glutamate, mice, knockout, antiporter, cataract, senile, cysteine
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):23. https://doi.org/10.1167/iovs.62.7.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Detection of reduced mitochondrial ROS production but increased ROS levels and oxidative damage in the young xCT knockout mouse retina

Luis James Knight; Renita M Martis; Monica L Acosta; Paul J Donaldson; Julie C Lim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2230.

ARVO Annual Meeting Abstract June 2021

Alterations to the hydrostatic pressure gradient modulate the subcellular distribution of water channel AQP5 in the rat lens

Rosica Stoyanova Petrova; Nikhil Nair; Kevin L Schey; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2098.

ARVO Annual Meeting Abstract June 2021

Blocking the lens microcirculation system has differential effects on the gradient of refractive index (GRIN) in the bovine lens

Yadi Chen; Chen Qiu; Xingzheng Pan; Ehsan Vaghefi; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2097.

ARVO Annual Meeting Abstract June 2021

Inhibition of water and solute fluxes by oxidative stress in a hyperbaric oxygen (HBO) model of lens ageing

Paul J Donaldson; Mitchell Nye-Wood; Yadi Chen; Tom White; Ehsan Vaghefi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2096.

ARVO Annual Meeting Abstract June 2021

Age-dependent changes to the free and total water distribution of the in vivo human lens measured by MRI

Alyssa Lesley Lie; Xingzheng Pan; Thomas William White; Paul J Donaldson; Ehsan Vaghefi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2095.

ARVO Annual Meeting Abstract June 2021

Spatial mapping of glucose uptake and metabolism in the bovine lens

Angus Grey; Ali Zahraei; Kyriakos Varnava; George Guo; Nicholas Demarais; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2080.

ARVO Annual Meeting Abstract June 2021

Inter-tissue antioxidant exchange between the lens and vitreous: A novel mechanism for maintaining high levels of ascorbate in the vitreous

Renita M Martis; Bo Li; Paul J Donaldson; Julie C Lim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2057.

Lens September 2020

Changes to Zonular Tension Alters the Subcellular Distribution of AQP5 in Regions of Influx and Efflux of Water in the Rat Lens

PDF

Rosica S. Petrova; Nandini Bavana; Rusin Zhao; Kevin L. Schey; Paul J. Donaldson
TAGS: lens (device), lens, crystalline, tissue membrane, water
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):36. https://doi.org/10.1167/iovs.61.11.36

Articles July 2020

Characterisation of Glutathione Export from Human Donor Lenses

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Bo Li; Ji-Youn Kim; Renita M. Martis; Paul J. Donaldson; Julie C. Lim
TAGS: donors, glutathione, glutathione disulfide, lens (device), lens, crystalline
Trans. Vis. Sci. Tech.. 2020; 9(8):37. https://doi.org/10.1167/tvst.9.8.37

Includes: Supplemental Content

Articles July 2020

Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens

PDF

Alyssa L. Lie; Xingzheng Pan; Thomas W. White; Paul J. Donaldson; Ehsan Vaghefi
TAGS: lens (device), lens, crystalline, magnetic resonance imaging, refractive errors, optics, aging, calibration
Trans. Vis. Sci. Tech.. 2020; 9(8):39. https://doi.org/10.1167/tvst.9.8.39

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Connexin 50 Influences the Physiological Optics of the In Vivo Mouse Lens

Presbyopia treatment with 1.25% pilocarpine alters free water distribution in the human lens

Imaging the activation of mechanosensitive signaling pathways in response in changes to zonular tension in different regions of the rat lens

Effect of TRPV1 activation on the accommodative changes in monkey crystalline lens shape, power, and stiffness

MP20 the forgotten lens membrane protein: old questions new views

Spatial assessment of UV-A exposure on bovine lenses: Towards a new cataract model

Age-Dependent Changes in the Water Content and Optical Power of the In Vivo Mouse Lens Revealed by Multi-Parametric MRI and Optical Modeling

Small molecule movement in the bovine lens – comparing and contrasting nutrient and pharmaceutical uptake and metabolism with MALDI mass spectrometry

Age-Dependent Changes in Total and Free Water Content of In Vivo Human Lenses Measured by Magnetic Resonance Imaging

Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice

Detection of reduced mitochondrial ROS production but increased ROS levels and oxidative damage in the young xCT knockout mouse retina

Alterations to the hydrostatic pressure gradient modulate the subcellular distribution of water channel AQP5 in the rat lens

Blocking the lens microcirculation system has differential effects on the gradient of refractive index (GRIN) in the bovine lens

Inhibition of water and solute fluxes by oxidative stress in a hyperbaric oxygen (HBO) model of lens ageing

Age-dependent changes to the free and total water distribution of the in vivo human lens measured by MRI

Spatial mapping of glucose uptake and metabolism in the bovine lens

Inter-tissue antioxidant exchange between the lens and vitreous: A novel mechanism for maintaining high levels of ascorbate in the vitreous

Changes to Zonular Tension Alters the Subcellular Distribution of AQP5 in Regions of Influx and Efflux of Water in the Rat Lens

Characterisation of Glutathione Export from Human Donor Lenses

Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens

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