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ARVO Annual Meeting Abstract June 2025

Comparative Analysis of the Fecal Microbiome and Blood Metabolome in OIR Mice

Yuhang Yang; Yulin Zhang; Qi Hui; Lijun Dong; Jie Sun; Zixin Fan; Xiaofeng Lu; Guoming Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2549.

ARVO Annual Meeting Abstract June 2025

Selective redox targeting of reactive myeloid cells by dendrimer-N-acetylsteine ameliorated vascular and neuronal injury in a mouse model of ischemic retinopathy

Yingxue Cao; Lingli Zhou; HAINING LU; Qiaoyan Hui; Siva P. Kambhampati; Jing Yang; Hongkwan Cho; Zhenhua Xu; Rico Gamuyao; Kannan Rangaramanujam; Elia J Duh

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1399.

ARVO Annual Meeting Abstract June 2025

Evaluation of the Visual Performance of Two Modified Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens Designs

Carly S Y Lam; Kenneth Liu; Han Yu Zhang; Hua Qi; Keigo Hasegawa; Shohei Matsuoka; Ka Yan Leung; Dennis Yan-yin Tse; Chi Ho To

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5194.

ARVO Annual Meeting Abstract June 2025

Short-term effect of second-generation defocus incorporated multiple segments spectacle lenses on choroidal thickness in children

Rachel Ka-man Chun; Kenneth Liu; Tsz Kin Law; Ying Hon; Hua Qi; Keigo Hasegawa; Carly S Y Lam; Chi-ho To; Dennis Yan-yin Tse

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2147.

Visual Neuroscience May 2025

Single-Cell RNA Sequencing of the Primary Visual Cortex in Mice With Optic Nerve Injury

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Deling Li; Bin Zou; Qinyuan Hu; Xinyi Zhang; Weiting Zeng; Liling Liu; Minbin Yu
TAGS: astrocytes, mice, optic nerve injuries, primary visual cortex, sequence analysis, rna, single-cell rna-seq, genes, microglia, alpha-crystallin b chain
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):31. https://doi.org/10.1167/iovs.66.5.31

Includes: Supplemental Content

Genetics March 2025

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

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Qiu-Yi Huo; Rui-Zheng Zhang; Wan-Nan Jia; Ya-Lei Wang; Xin Shen; Xin-Yao Chen; Tian-Hui Chen; Yan Liu; Ling-Hao Song; Xinyue Wang; Yong Lv; Ze-Xu Chen; Yong-Xiang Jiang
TAGS: biomechanics, cornea, ectopia lentis, fibrillin-1, marfan syndrome, mutation, genotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):23. https://doi.org/10.1167/iovs.66.3.23

Includes: Supplemental Content

Cornea March 2025

Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium

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Zhao-Jing Lu; Jin-Guo Ye; Jing-Ni Li; Jiang-Bo Liang; Ming Zhou; Qiu-Ling Hu; Qi-Kai Zhang; Yu-Heng Lin; Ying-Feng Zheng
TAGS: corneal epithelium, genes, mice, wounds and injuries, chromatin, cornea, wound healing, multiomics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):9. https://doi.org/10.1167/iovs.66.3.9

Includes: Supplemental Content

Lens February 2025

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

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Yan Liu; Xinyue Wang; Linghao Song; Yang Sun; Zexu Chen; Wannan Jia; Xin Shen; Yalei Wang; Xinyao Chen; Qiuyi Huo; Pranav Prakash Edavi; Tianhui Chen; Yongxiang Jiang
TAGS: ectopia lentis, eye, intelligence, intraocular lens implant device, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(2):5. https://doi.org/10.1167/tvst.14.2.5

Includes: Supplemental Content

Anatomy and Pathology/Oncology January 2025

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

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Yanjing Huang; Chengjie He; Qiuling Hu; Zhong Liu; Xingyi Li; Wuyou Gao; Xuanwei Liang; Rongxin Chen; Zhen Mao; Xianchai Lin
TAGS: basal cell carcinoma, eyelid, genes, infiltrative basal cell carcinoma, metabolites, neoplasms, metabolic disturbance, tumor microenvironment, up-regulation (physiology), spectrometry, mass, matrix-assisted laser desorption-ionization
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):11. https://doi.org/10.1167/iovs.66.1.11

Includes: Supplemental Content

Retinal Cell Biology January 2025

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

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Ao-Wang Qiu; Ning-Yu Wang; Wen-Jie Yin; Zhao-Qi Zhu; Qing-Huai Liu; Wei-Wei Zhang
TAGS: cardiac support procedures, exosomes, interleukin-17, mast-cell sarcoma, millennium cohort study, minimally conscious state, diabetic retinopathy, interleukins, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):1. https://doi.org/10.1167/iovs.66.1.1

Cornea September 2024

Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys

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Ming Zhou; Zhuo-Xing Shi; Zhong Liu; Shu-Rui Ke; Chao-Yang Wang; Xiao-Lin Liang; Qiu-Ling Hu; Qi-Kai Zhang; Dong-Liang Wang; Li Sun; Yu-Heng Lin; Qi Dai; Ying-Feng Zheng
TAGS: cornea, corneal epithelium, genes, macaca fascicularis, wound healing, epithelium, transcription, genetic, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):43. https://doi.org/10.1167/iovs.65.11.43

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Noninflammatory lipid nanoparticles induce Treg expansion and suppress experimental autoimmune uveitis in vivo

Wen Shi; Huishi Wang; Qiuling Hu; Qikai Zhang; Caineng Pan; Jinshan Lin; Jinguo Ye; Yizhi Liu; Yingfeng Zheng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5067.

Glaucoma March 2024

Natural History and Risk Factors for Glaucoma Progression in Chinese Patients With Normal-Tension Glaucoma

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De-Fu Chen; Chenmin Wang; Yuqing Si; Xiaonan Lu; Weihe Zhou; Qiangjie Huang; Jingjing Zuo; Gangwei Cheng; Dexter Y. L. Leung; Ningli Wang; David S. Friedman; Yuanbo Liang
TAGS: chinese (other dialects), chinese people, did not receive therapy or drug, glaucoma, low tension glaucoma, natural history, risk factors, follow-up
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):28. https://doi.org/10.1167/iovs.65.3.28

Includes: Supplemental Content

Genetics February 2024

m 6 A-Mediated Upregulation of Imprinted in Prader–Willi Syndrome Induces Aberrant Apical–Basal Polarization and Oxidative Damage in RPE Cells

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Ying Wang; Ye-Ran Zhang; Zi-Qin Ding; Yi-Chen Zhang; Ru-Xu Sun; Hong-Jing Zhu; Jia-Nan Wang; Bei Xu; Ping Zhang; Jiang-Dong Ji; Qing-Huai Liu; Xue Chen
TAGS: mtor serine-threonine kinases, prader-willi syndrome, proto-oncogene proteins c-akt, retinal pigment cell, rna, up-regulation (physiology), proteins, protein overexpression, rapamycin, immunoblotting
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):10. https://doi.org/10.1167/iovs.65.2.10

Includes: Supplemental Content

Retina January 2024

Response of Human Retinal Microvascular Endothelial Cells to Influenza A (H1N1) Infection and the Underlying Molecular Mechanism

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Shuo Yang; Zixin Fan; Xiaofeng Lu; Hui Liu; Ziying Zhou; Hui Qi; Jian Zeng; Mianying Zheng; Xuan Zou; Shisong Fang; Guoming Zhang
TAGS: infections, influenza a virus, h1n1 subtype, swine influenza, endothelial cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):38. https://doi.org/10.1167/iovs.65.1.38

ARVO Annual Meeting Abstract June 2023

TNFα secreted by DNA-sensing in macrophage compromises retinal pigment epithelial barrier function

Yi Bao; Michael Twarog; Joshua Schustak; YongYao Xu; Matthew Coble; Katie Dolan; Robert Esterberg; Qian Huang; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2963.

ARVO Annual Meeting Abstract June 2023

Biomarker identification by proteomic analysis of vitreous humor and plasma from diabetic retinopathy patients

Qin Zhang; Angela Banks; Rebecca Stacy; Ning Li; Yesel Kim; Lori Jennings; Nancy Finkel; Joseph Loureiro; Anfan Wu; Amy Chen; Cynthia L Grosskreutz; Qian Huang; Ganesh Prasanna

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):555.

ARVO Annual Meeting Abstract June 2023

Rat choroid single cell RNAseq reveals endothelial-to-mesenchymal transition as a potential mechanisms of choroid ischemia

Si Tong Huo; Yuntao Hu; Mengda Li; Jie Na; Hui Qiu; Peiliang Wang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4512.

ARVO Annual Meeting Abstract June 2023

How to evaluate optical performance of DIMS spectacle lens

Hua Qi; Shohei Matsuoka

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4947.

Retina May 2023

Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

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Jiaxing Zhou; Sen Lin; Qiumei Hu; Xue Li; Xi Chen; Linlin Luo; Shiyang Ye; Wei Liu; Jian Ye
TAGS: insulin-like growth factor i, macrophage-1 antigen, microglia, phagocytosis, optic nerve injuries
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):7. https://doi.org/10.1167/iovs.64.5.7

Includes: Supplemental Content

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Comparative Analysis of the Fecal Microbiome and Blood Metabolome in OIR Mice

Selective redox targeting of reactive myeloid cells by dendrimer-N-acetylsteine ameliorated vascular and neuronal injury in a mouse model of ischemic retinopathy

Evaluation of the Visual Performance of Two Modified Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens Designs

Short-term effect of second-generation defocus incorporated multiple segments spectacle lenses on choroidal thickness in children

Single-Cell RNA Sequencing of the Primary Visual Cortex in Mice With Optic Nerve Injury

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys

Noninflammatory lipid nanoparticles induce Treg expansion and suppress experimental autoimmune uveitis in vivo

Natural History and Risk Factors for Glaucoma Progression in Chinese Patients With Normal-Tension Glaucoma

m 6 A-Mediated Upregulation of Imprinted in Prader–Willi Syndrome Induces Aberrant Apical–Basal Polarization and Oxidative Damage in RPE Cells

Response of Human Retinal Microvascular Endothelial Cells to Influenza A (H1N1) Infection and the Underlying Molecular Mechanism

TNFα secreted by DNA-sensing in macrophage compromises retinal pigment epithelial barrier function

Biomarker identification by proteomic analysis of vitreous humor and plasma from diabetic retinopathy patients

Rat choroid single cell RNAseq reveals endothelial-to-mesenchymal transition as a potential mechanisms of choroid ischemia

How to evaluate optical performance of DIMS spectacle lens

Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

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