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Retina January 2025

ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

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Yingwei Wang; Pangfeng Wang; Zhen Yi; Jiamin Ouyang; Yi Jiang; Shiqiang Li; Xiaoyun Jia; Xueshan Xiao; James Fielding Hejtmancik; Wenmin Sun; Qingjiong Zhang
TAGS: abca4 gene, introns, phenotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):65. https://doi.org/10.1167/iovs.66.1.65

Includes: Supplemental Content

Retina December 2024

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

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Yuhui Pang; Chaokun Luo; Qingruo Zhang; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen; Hui Chen
TAGS: anti-vascular endothelial growth factor therapy, diabetes mellitus, diabetic retinopathy, edema, machine learning, multiomics, macula lutea, hypertension, nonproliferative diabetic retinopathy, metabolomics
Trans. Vis. Sci. Tech.. 2024; 13(12):23. https://doi.org/10.1167/tvst.13.12.23

Includes: Supplemental Content

Cornea & External Disease September 2024

Drug-Related Keratitis: A Real-World FDA Adverse Event Reporting System Database Study

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Shi-Nan Wu; Xiao-Dong Chen; Qing-He Zhang; Yu-Qian Wang; Dan Yan; Chang-Sheng Xu; Shao-Pan Wang; Linfangzi Zhu; Dan-Yi Qin; Shu-Jia Guo; Lin Chen; Yu-Wen Liu; Caihong Huang; Jiaoyue Hu; Zuguo Liu
TAGS: keratitis, united states food and drug administration, incident reporting
Trans. Vis. Sci. Tech.. 2024; 13(9):17. https://doi.org/10.1167/tvst.13.9.17

Includes: Supplemental Content

Genetics August 2024

The Systemic Genotype-Phenotype Characterization of PAX6 -Related Eye Disease in 164 Chinese Families

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Yi Jiang; Zhen Yi; Yuxi Zheng; Jiamin Ouyang; Dongwei Guo; Shiqiang Li; Xueshan Xiao; Panfeng Wang; Wenmin Sun; Qingjiong Zhang
TAGS: pax6 transcription factor, phenotype, family, eye, eye diseases, cohort studies, genotype, chinese (other dialects), chinese people
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):46. https://doi.org/10.1167/iovs.65.10.46

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Multi-omics of retinas from free-ranging primates with naturally occurring thin retinal nerve fiber layer

Amanda Melin; David Young; Arthur Fernandes; Rachel Munds; Arturo Barron-Arrambide; Palaiologos Alexopoulos; CBRU Cayo Biobank Research Unit; Michael Montague; Armando Burgos-Rodriguez; Melween I Martinez; Daniel Promislow; Gadi Wollstein; John Danias; James Higham; Qingrun Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):656.

ARVO Annual Meeting Abstract June 2024

COL2A1 -associated Stickler syndrome in Chinese children: clinical and genetic risk factors underlying the serious consequence

Yi Jiang; Qingjiong Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3843.

ARVO Annual Meeting Abstract June 2024

Genetic Landscape and Clinical Profiles of Stargard’t disease in a Large Chinese Cohort with Stargardt's Disease

Yingwei Wang; Qingjiong Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6038.

ARVO Annual Meeting Abstract June 2024

ICL Realignment, Exchange or Explantation – A five-year Review of 18043 eyes

Hongting Liu; Qingsong Zhang; yulin liu; mei feng; xiongzi liang; xiuli xie; qifeng wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2871.

Clinical Trials January 2024

Efficacy of Morning Versus Evening Latanoprost/Timolol Fixed Combination for Open-Angle Glaucoma and Ocular Hypertension: A Randomized Clinical Trial

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Hui Feng; Dong Han; Wensheng Lu; Guangxian Tang; Hengli Zhang; Sujie Fan; Aiguo Lv; Jing Jiang; Qing Zhang; Ye Zhang; Kai Cao; Zhi Li; Shuning Li
TAGS: clinical trials, intraocular pressure, latanoprost, ocular hypertension, open-angle glaucoma, timolol
Trans. Vis. Sci. Tech.. 2024; 13(1):21. https://doi.org/10.1167/tvst.13.1.21

Includes: Supplemental Content

Genetics January 2024

Clinical and Genetic Landscape of Ectopia Lentis Based on a Cohort of Patients From 156 Families

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Dongwei Guo; Shiqiang Li; Xueshan Xiao; Yi Jiang; Yingwei Wang; Guangming Jin; Junwen Wang; Jiamin Ouyang; Xiaoyun Jia; Wenmin Sun; Panfeng Wang; Danying Zheng; Qingjiong Zhang
TAGS: cohort studies, ectopia lentis, family, fibrillin-1, genetics, genes, genotype, phenotype
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):20. https://doi.org/10.1167/iovs.65.1.20

Includes: Supplemental Content

Retina December 2023

Double Hyperautofluorescence Rings as a Sign of CFAP410 -related Retinopathy

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Xueqing Li; Yingwei Wang; Junwen Wang; Panfeng Wang; Qingjiong Zhang
TAGS: phenotype, retinal diseases, retinitis pigmentosa, electroretinography, retinal degeneration
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):44. https://doi.org/10.1167/iovs.64.15.44

Includes: Supplemental Content

Genetics April 2023

Unique Haplotypes in OPN1LW as a Common Cause of High Myopia With or Without Protanopia: A Potential Window Into Myopic Mechanism

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Yingwei Wang; Wenmin Sun; Xueshan Xiao; Yi Jiang; Jiamin Ouyang; Junwen Wang; Zhen Yi; Shiqiang Li; Xiaoyun Jia; Panfeng Wang; J. Fielding Hejtmancik; Qingjiong Zhang
TAGS: haplotypes, myopia, retinal cone, genes, mosaicism, family
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):29. https://doi.org/10.1167/iovs.64.4.29

Includes: Supplemental Content

Glaucoma March 2023

Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes

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Caixia Li; Yanyan Cheng; Ye Zhang; Xiaohua Pan; Hui Feng; Fei Xiang; Meijuan Zhang; Qianqian Ji; Zhi Li; Na Jiang; Qing Zhang; Shuning Li
TAGS: eye, ganglia, optic disk, retinal nerve fiber layer
Trans. Vis. Sci. Tech.. 2023; 12(3):26. https://doi.org/10.1167/tvst.12.3.26

Genetics March 2023

The Genetic Confirmation and Clinical Characterization of LOXL3 -Associated MYP28: A Common Type of Recessive Extreme High Myopia

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Yi Jiang; Lin Zhou; Yingwei Wang; Jiamin Ouyang; Shiqiang Li; Xueshan Xiao; Xiaoyun Jia; Junwen Wang; Zhen Yi; Wenmin Sun; Xiaodong Jiao; Panfeng Wang; J. Fielding Hejtmancik; Qingjiong Zhang
TAGS: genetics, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):24. https://doi.org/10.1167/iovs.64.3.24

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2023

Missense Mutations in MAB21L1 : Causation of Novel Autosomal Dominant Ocular BAMD Syndrome

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Panfeng Wang; Pengsen Wu; Junwen Wang; Yiyan Zeng; Yi Jiang; Yingwei Wang; Shiqiang Li; Xueshan Xiao; Qingjiong Zhang
TAGS: missense mutation, phenotype, syndrome, family
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):19. https://doi.org/10.1167/iovs.64.3.19

Includes: Supplemental Content

Glaucoma January 2023

Anterior Segment Characteristics and Risk Factors for Primary Angle Closure Disease With Long Axial Lengths: The Handan Eye Study

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Ye Zhang; Qing Zhang; Si Zhen Li; Ming Guang He; Shu Ning Li; Ning Li Wang
TAGS: eye, phased thoracic-abdominal compression-decompression, risk factors, anterior chamber of eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):8. https://doi.org/10.1167/iovs.64.1.8

Includes: Supplemental Content

Genetics August 2022

Clinical and Genetic Analysis of RDH12 -Associated Retinopathy in 27 Chinese Families: A Hypomorphic Allele Leads to Cone-Rod Dystrophy

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Junwen Wang; Yingwei Wang; Shiqiang Li; Xueshan Xiao; Zhen Yi; Yi Jiang; Xueqing Li; Xiaoyun Jia; Panfeng Wang; Chenjin Jin; Wenmin Sun; Qingjiong Zhang
TAGS: alleles, family, retinal diseases, retinitis pigmentosa, genetic analysis, chinese (other dialects), phenotype, chinese people
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):24. https://doi.org/10.1167/iovs.63.9.24

Includes: Supplemental Content

Genetics May 2022

Different Phenotypes Represent Advancing Stages of ABCA4 -Associated Retinopathy: A Longitudinal Study of 212 Chinese Families From a Tertiary Center

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Yingwei Wang; Wenmin Sun; Jing Zhou; Xueqing Li; Yi Jiang; Shiqiang Li; Xiaoyun Jia; Xueshan Xiao; Jiamin Ouyang; Yueye Wang; Lin Zhou; Yuxi Long; Mengchu Liu; Yongyu Li; Zhen Yi; Panfeng Wang; Qingjiong Zhang
TAGS: abca4 gene, chinese (other dialects), chinese people, longitudinal studies, phenotype, retinal diseases, family
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):28. https://doi.org/10.1167/iovs.63.5.28

Includes: Supplemental Content

Genetics May 2022

Autosomal Dominant Retinitis Pigmentosa–Associated TOPORS Protein Truncating Variants Are Exclusively Located in the Region of Amino Acid Residues 807 to 867

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Junwen Wang; Yingwei Wang; Yi Jiang; Xueqing Li; Xueshan Xiao; Shiqiang Li; Xiaoyun Jia; Wenmin Sun; Panfeng Wang; Qingjiong Zhang
TAGS: amino acids, proteins, retinitis pigmentosa, datasets, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):19. https://doi.org/10.1167/iovs.63.5.19

Includes: Supplemental Content

Genetics August 2021

Genotype-Phenotype of Isolated Foveal Hypoplasia in a Large Cohort: Minor Iris Changes as an Indicator of PAX6 Involvement

PDF

Yi Jiang; Shiqiang Li; Xueshan Xiao; Wenmin Sun; Qingjiong Zhang
TAGS: cohort studies, foveal hypoplasia, iris, pathologic nystagmus, pax6 transcription factor, phenotype, genotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):23. https://doi.org/10.1167/iovs.62.10.23

Includes: Supplemental Content

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ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

Drug-Related Keratitis: A Real-World FDA Adverse Event Reporting System Database Study

The Systemic Genotype-Phenotype Characterization of PAX6 -Related Eye Disease in 164 Chinese Families

Multi-omics of retinas from free-ranging primates with naturally occurring thin retinal nerve fiber layer

COL2A1 -associated Stickler syndrome in Chinese children: clinical and genetic risk factors underlying the serious consequence

Genetic Landscape and Clinical Profiles of Stargard’t disease in a Large Chinese Cohort with Stargardt's Disease

ICL Realignment, Exchange or Explantation – A five-year Review of 18043 eyes

Efficacy of Morning Versus Evening Latanoprost/Timolol Fixed Combination for Open-Angle Glaucoma and Ocular Hypertension: A Randomized Clinical Trial

Clinical and Genetic Landscape of Ectopia Lentis Based on a Cohort of Patients From 156 Families

Double Hyperautofluorescence Rings as a Sign of CFAP410 -related Retinopathy

Unique Haplotypes in OPN1LW as a Common Cause of High Myopia With or Without Protanopia: A Potential Window Into Myopic Mechanism

Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes

The Genetic Confirmation and Clinical Characterization of LOXL3 -Associated MYP28: A Common Type of Recessive Extreme High Myopia

Missense Mutations in MAB21L1 : Causation of Novel Autosomal Dominant Ocular BAMD Syndrome

Anterior Segment Characteristics and Risk Factors for Primary Angle Closure Disease With Long Axial Lengths: The Handan Eye Study

Clinical and Genetic Analysis of RDH12 -Associated Retinopathy in 27 Chinese Families: A Hypomorphic Allele Leads to Cone-Rod Dystrophy

Different Phenotypes Represent Advancing Stages of ABCA4 -Associated Retinopathy: A Longitudinal Study of 212 Chinese Families From a Tertiary Center

Autosomal Dominant Retinitis Pigmentosa–Associated TOPORS Protein Truncating Variants Are Exclusively Located in the Region of Amino Acid Residues 807 to 867

Genotype-Phenotype of Isolated Foveal Hypoplasia in a Large Cohort: Minor Iris Changes as an Indicator of PAX6 Involvement

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