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Retina October 2024

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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Xiao Xie; Wenqi Wang; Hongyan Wang; Zhiping Zhang; Xiaomeng Yuan; Yanmei Shi; Yanfeng Liu; Qingjun Zhou; Tingting Liu
TAGS: artificial intelligence, biological markers, diabetes mellitus, type 2, diabetic nephropathy, perfusion, screening, random forest, complex
Trans. Vis. Sci. Tech.. 2024; 13(10):19. https://doi.org/10.1167/tvst.13.10.19

Cornea September 2024

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

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Yunhai Dai; Shilan Mao; Xinyi Zang; Hongqi Ge; Jing Feng; Yalin Wang; Xia Qi; Lingling Yang; Qingjun Zhou; Xiaolei Wang
TAGS: cornea, diabetes mellitus, type 2, human herpesvirus 1, infections, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):36. https://doi.org/10.1167/iovs.65.11.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

An epithelial cell-derived neurotrophins secretion regulated by norephinephrine/ADRB2 signaling

Ya Li; Qingjun Zhou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2631.

ARVO Annual Meeting Abstract June 2024

A gatekeeper noradrenergic neural control of tear secretion through the NA-Adra1a-Ucp2 pathway

Qingjun Zhou; Mingli Qu; Qun Wang; Xiaofei Bai; Jing Feng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5724.

ARVO Annual Meeting Abstract June 2024

The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration

Yang Lingling; Rong Chen; Yao Wang; Qingjun Zhou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):54.

Glaucoma May 2024

VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model

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Jingyi Wu; Longfang Zhou; Yameng Liu; Xiaowei Zhang; Yuanhang Yang; Xinyuan Zhu; Qianwen Bu; Xinmiao Shan; Jia Yin; Robert N. Weinreb; Qingjun Zhou; Xiaojing Pan; Alex S. Huang
TAGS: blister, fluorouracil, oryctolagus cuniculus, surgical procedures, operative, trabeculectomy, vascular endothelial growth factor c, glaucoma, glaucoma surgery
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):32. https://doi.org/10.1167/iovs.65.5.32

Cornea May 2024

The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration

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Rong Chen; Yao Wang; Zhenzhen Zhang; Xiaolei Wang; Ya Li; Min Wang; Huifeng Wang; Muchen Dong; Qingjun Zhou; Lingling Yang
TAGS: cornea, epithelium, mice, nerve regeneration, stress, signal transduction, endoplasmic reticulum, wound healing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):8. https://doi.org/10.1167/iovs.65.5.8

Includes: Supplemental Content

Biochemistry and Molecular Biology April 2024

Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease

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Yang Tang; Shengqian Dou; Chao Wei; Ziwen Sun; Di Sun; Qingjun Zhou; Lixin Xie
TAGS: acinar cells, cell nucleus, dry eye syndromes, genes, heterogeneity, immunologic cells, lacrimal gland, langer-giedion syndrome, mice, scopolamine
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):46. https://doi.org/10.1167/iovs.65.4.46

Includes: Supplemental Content

Physiology and Pharmacology April 2024

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

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Linyan Ma; Lingling Yang; Xiaolei Wang; Leilei Zhao; Xiaofei Bai; Xia Qi; Qing Chen; Ya Li; Qingjun Zhou
TAGS: bodily secretions, calcitonin gene-related peptide, cornea, lacrimal gland, mice, sensory nerves, trpv1 receptor, capsaicin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):30. https://doi.org/10.1167/iovs.65.4.30

Includes: Supplemental Content

Cornea December 2023

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

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Jing Feng; Lingling Yang; Lili Ran; Xia Qi; Xiaolei Wang; Yangyang Zhang; Zongzheng Zou; Ting Liu; Xiaochuan Wang; Yang Yu; Xiaodong Sun; Qingjun Zhou
TAGS: cornea, human herpesvirus 1, infections, keratitis, herpetic, macrophage-1 antigen, mice, symptom aggravating factors, viral load result
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):24. https://doi.org/10.1167/iovs.64.15.24

Includes: Supplemental Content

Cornea May 2023

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

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Bi Ning Zhang; Benxiang Qi; Wai Kit Chu; Fangying Song; Suxia Li; Qiaoqiao Dong; Zheng Shao; Bin Zhang; Xianli Du; Xiubin Ma; Vishal Jhanji; Qingjun Zhou
TAGS: adrb2 gene, beta-2 adrenergic receptors, contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):26. https://doi.org/10.1167/iovs.64.5.26

Includes: Supplemental Content

Cornea March 2023

Overactivation of Norepinephrine–β2-Adrenergic Receptor Axis Promotes Corneal Neovascularization

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Qiaoqiao Dong; Benxiang Qi; Bin Zhang; Xiaoyun Zhuang; Shijiu Chen; Qingjun Zhou; Bi Ning Zhang; Suxia Li
TAGS: choroidal neovascularization, cornea, corneal neovascularization, mice, norepinephrine, sutures, fibroblast growth factor 2, alkalies
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):20. https://doi.org/10.1167/iovs.64.3.20

Includes: Supplemental Content

Cornea & External Disease February 2023

Norepinephrine as an Enhancer Promoting Corneal Penetration of Riboflavin for Transepithelial Corneal Crosslinking

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Guoying Liu; Tan Li; Benxiang Qi; Ganyu Gong; Tengyou Guo; Qingjun Zhou; Vishal Jhanji; Bi Ning Zhang; Xianli Du
TAGS: cornea, corneal collagen cross-linking, norepinephrine, riboflavin, enhancer of transcription
Trans. Vis. Sci. Tech.. 2023; 12(2):21. https://doi.org/10.1167/tvst.12.2.21

Includes: Supplemental Content

Cornea January 2023

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

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Lili Ran; Jing Feng; Xia Qi; Ting Liu; Benxiang Qi; Kai Jiang; Zhenzhen Zhang; Yang Yu; Qingjun Zhou; Lixin Xie
TAGS: cornea, epithelium, mice, wound healing
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):19. https://doi.org/10.1167/iovs.64.1.19

Includes: Supplemental Content

Cornea March 2022

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

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Chen Chen; Bin Zhang; Junfa Xue; Zongyi Li; Shengqian Dou; Huilin Chen; Qun Wang; Mingli Qu; Huifeng Wang; Yuan Zhang; Luqin Wan; Qingjun Zhou; Lixin Xie
TAGS: cornea, corneal endothelium, diabetes mellitus, endothelial dysfunction, stress, mice, endothelial cells, mitochondria, corneal edema, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):4. https://doi.org/10.1167/iovs.63.3.4

Includes: Supplemental Content

Glaucoma August 2021

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

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Shangru Sui; Hongxia Yu; Xiangji Wang; Wenyan Wang; Xuejiao Yang; Xiaojing Pan; Qingjun Zhou; Chen Xin; Rong Du; Shen Wu; Jingxue Zhang; Qilong Cao; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cell growth, connexin 43, gap junction protein, glaucoma, medication therapy management, mice, trabecular meshwork, myoc gene, coculture techniques, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):28. https://doi.org/10.1167/iovs.62.10.28

Includes: Supplemental Content

Articles August 2021

Biomechanical Effects of Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty for Keratoconus: A Finite Element Analysis

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Hua Li; Min Chen; Qingjun Zhou; Xiaojing Pan; Jun Cheng; Lin Cong; Ting Zhang; Yanling Dong; Lixin Xie
TAGS: cornea, keratoconus, keratoplasty, stress, keratoplasty, penetrating, finite element analysis, intraocular pressure
Trans. Vis. Sci. Tech.. 2021; 10(9):15. https://doi.org/10.1167/tvst.10.9.15

Includes: Supplemental Content

Articles May 2021

Xeno- and Feeder-Free Differentiation of Human iPSCs to Trabecular Meshwork-Like Cells by Recombinant Cytokines

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Wenyan Wang; Yongzhen Miao; Shangru Sui; Yanan Wang; Shen Wu; Qilong Cao; Haoyun Duan; Xia Qi; Qingjun Zhou; Xiaojing Pan; Jingxue Zhang; Xuehong Chen; Yantao Han; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cytokine, culture media, conditioned, reverse transcriptase polymerase chain reaction
Trans. Vis. Sci. Tech.. 2021; 10(6):27. https://doi.org/10.1167/tvst.10.6.27

Includes: Supplemental Content

Cornea April 2020

Extended Contact Lens Wear Promotes Corneal Norepinephrine Secretion and Pseudomonas aeruginosa Infection in Mice

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Jie Li; Xiubin Ma; Lianghui Zhao; Ya Li; Qingjun Zhou; Xianli Du
TAGS: contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa infections, bodily secretions, biofilms, capillary leak syndrome
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):17. https://doi.org/10.1167/iovs.61.4.17

Articles February 2020

PTEN Inhibition Facilitates Diabetic Corneal Epithelial Regeneration by Reactivating Akt Signaling Pathway

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Jing Li; Xia Qi; Xiaochuan Wang; Weina Li; Ya Li; Qingjun Zhou
TAGS: cornea, diabetes mellitus, epithelium, pten gene, mice, akt signaling pathway
Trans. Vis. Sci. Tech.. 2020; 9(3):5. https://doi.org/10.1167/tvst.9.3.5

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Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

An epithelial cell-derived neurotrophins secretion regulated by norephinephrine/ADRB2 signaling

A gatekeeper noradrenergic neural control of tear secretion through the NA-Adra1a-Ucp2 pathway

The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration

VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model

The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration

Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

Overactivation of Norepinephrine–β2-Adrenergic Receptor Axis Promotes Corneal Neovascularization

Norepinephrine as an Enhancer Promoting Corneal Penetration of Riboflavin for Transepithelial Corneal Crosslinking

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

Biomechanical Effects of Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty for Keratoconus: A Finite Element Analysis

Xeno- and Feeder-Free Differentiation of Human iPSCs to Trabecular Meshwork-Like Cells by Recombinant Cytokines

Extended Contact Lens Wear Promotes Corneal Norepinephrine Secretion and Pseudomonas aeruginosa Infection in Mice

PTEN Inhibition Facilitates Diabetic Corneal Epithelial Regeneration by Reactivating Akt Signaling Pathway

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