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Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Intravitreal AAV2 gene delivery to feline retinal ganglion cells (RGCs)

Kazuya Oikawa; Julie Kiland; Seth Eaton; Odalys Torne; Virginia Mathu; Robert W Nickells; Gillian J McLellan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3848.

ARVO Annual Meeting Abstract June 2022

Utility of UW-based solutions for reducing apoptotic signaling and retinal ganglionic cell death in a whole eye transplantation rodent model

Neil J Khatter; Charles R Owens; Bing Li; Yong Wang; Alkesh Jani; Christene Huang; Robert W Nickells; An-Jey Su; Kia M Washington

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3158 – F0432.

Glaucoma August 2021

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

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Heather M. Schmitt; Rachel L. Fehrman; Margaret E. Maes; Huan Yang; Lian-Wang Guo; Cassandra L. Schlamp; Heather R. Pelzel; Robert W. Nickells
TAGS: apoptosis, disease susceptibility, immunohistochemistry, mice, neurons, plasmids, signal transduction, proteins, caspase-3, histone deacetylase
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):14. https://doi.org/10.1167/iovs.62.10.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Bclx gene therapy prevents BAX activation and preserves retinal ganglion cell axons in the DBA/2J glaucoma model.

Ryan Donahue; Jenna R. Gustafson; Rachel Fehrman; Margaret Maes; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):659.

ARVO Annual Meeting Abstract June 2020

Live Cell Imaging of BAX Recruitment in Retinal Ganglion Cells Reveals Characteristics of Anoikis

Robert W Nickells; Margaret E. Maes; Ryan Donahue; Jenna R. Gustafson; Donna M Peters

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4334.

ARVO Annual Meeting Abstract July 2019

Exploring the Role of BAX in the Degeneration of Retinal Ganglion Cell Axons and Dendritic Arbors

Ryan Joseph Donahue; Briana N. Ebbinghaus; Mrinalini Hoon; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):651.

Glaucoma December 2017

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

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Robert W. Nickells; Heather M. Schmitt; Margaret E. Maes; Cassandra L. Schlamp
TAGS: mice, optic nerve, optic nerve injuries, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6091-6104. https://doi.org/10.1167/iovs.17-22634

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Delayed RGC death and persistent JNK activation following optic nerve injury in BAX deficient mice

Ryan Donahue; Joshua Grosser; Margaret Maes; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2538.

ARVO Annual Meeting Abstract June 2017

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Heather M Schmitt; Cassandra Schlamp; Huan Yang; Lian-Wang Guo; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2539.

ARVO Annual Meeting Abstract June 2017

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4081.

ARVO Annual Meeting Abstract June 2017

A Retinal Ganglion Cell Targting and Protecting Intraocular Drug Delivery System Using Unimolecular Nanoparticles

Lianwang Guo; Lei Zhao; Guojun Chen; Jun Li; Yingmei Fu; Timur Mavlyutov; Annie Yao; Robert W Nickells; Shaoqin Gong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4109.

ARVO Annual Meeting Abstract September 2016

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):706.

ARVO Annual Meeting Abstract September 2016

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Heather M Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2554.

ARVO Annual Meeting Abstract September 2016

Mechanisms of Retinal Ganglion Cell Survival in Zebrafish after Axon Injury

Jonathan Mikal Skarie; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2555.

ARVO Annual Meeting Abstract September 2016

Comparison of Transcriptomes of Models of Optic Nerve Injury

Ryan Donahue; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4787.

Research Highlight September 2015

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy

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Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(10):6113. https://doi.org/10.1167/iovs.15-17997

ARVO Annual Meeting Abstract June 2015

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

Caitlin Mac Nair; Cassandra Schlamp; Valery I Shestopalov; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4948.

ARVO Annual Meeting Abstract June 2015

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Margaret Maes; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4952.

ARVO Annual Meeting Abstract June 2015

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

Heather Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2425.

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Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Intravitreal AAV2 gene delivery to feline retinal ganglion cells (RGCs)

Utility of UW-based solutions for reducing apoptotic signaling and retinal ganglionic cell death in a whole eye transplantation rodent model

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

Bclx gene therapy prevents BAX activation and preserves retinal ganglion cell axons in the DBA/2J glaucoma model.

Live Cell Imaging of BAX Recruitment in Retinal Ganglion Cells Reveals Characteristics of Anoikis

Exploring the Role of BAX in the Degeneration of Retinal Ganglion Cell Axons and Dendritic Arbors

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

Delayed RGC death and persistent JNK activation following optic nerve injury in BAX deficient mice

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

A Retinal Ganglion Cell Targting and Protecting Intraocular Drug Delivery System Using Unimolecular Nanoparticles

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Mechanisms of Retinal Ganglion Cell Survival in Zebrafish after Axon Injury

Comparison of Transcriptomes of Models of Optic Nerve Injury

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

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