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Meeting Abstract (52)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (52)
Journal of Vision (1)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (52)
Methods (1)
Optica Fall Vision Meeting Abstract (1)

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Nanotechnology and Regenerative Medicine (1)
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Visual Psychophysics and Physiological Optics (1)

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ARVO Annual Meeting Abstract June 2024

Developing iPSC-derived RPE cell replacement therapy for the treatment of AMD

Ruchi Sharma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):8.

ARVO Annual Meeting Abstract June 2024

Localization of Toll-like Receptors and Intracellular Lipid Droplets in an anaphylatoxin-induced AMD model in iPSC-derived retinal pigment epithelium

Katherine Patterson; Congxiao Zhang; Andrew Fausey; David McGaughey; Joys Annita David; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):739.

ARVO Annual Meeting Abstract June 2024

Interferon regulatory factor 5 (IRF5) gene ablation causes senescencent changes in mouse choroid

Congxiao Zhang; Russell Quinn; Joys Annita David; Katherine Patterson; Eric Nguyen; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):732.

ARVO Annual Meeting Abstract June 2024

USE OF METFORMIN AS A POTENTIAL TREATMENT FOR STARGARDT MACULOPATHY

Devika Abhijit Bose; Mitra Farnoodian; Ruchi Sharma; David McGaughey; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2203.

ARVO Annual Meeting Abstract June 2024

Deciphering Shared Phenotypic Traits in iPSC-Derived RPE from Ciliopathy Patients with Mutation-Specific Variations

Dominik Reichert; Davide Ortolan; Jair Montford; Jiwon Ryu; Colby F. Lewallen; Devika Bose; Keren Melendez; Laryssa Huryn; Wadih M Zein; Brian Patrick Brooks; Helen Louise May-Simera; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3821.

ARVO Annual Meeting Abstract June 2024

Analysis of Primary Cilia Phenotypes in Patient-Derived iPSC-RPE

Keren Melendez; Dominik Reichert; Colby F. Lewallen; Davide Ortolan; Jair Montford; Jiwon Ryu; Devika Abhijit Bose; Wadih M Zein; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4523.

ARVO Annual Meeting Abstract June 2024

3D organelle map of polarized iPSC-RPE using high-content imaging and volumetric segmentation

Davide Ortolan; Pushkar Sathe; Andrei Volkov; Dominik Reichert; Sheldon Sebastian; Nicholas Schaub; Gianluca Pegoraro; Arvydas Maminishkis; Ruchi Sharma; Peter Bajcsy; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4515.

ARVO Annual Meeting Abstract June 2024

Investigating the Retinotoxic Effects of Hydroxychloroquine: An In Vitro iPSC-RPE Model to Probe Genetics, Mechanism, and Develop Potential Therapies

Helena Herzog; Jair Montford; Devika Bose; Kapil Bharti; Ruchi Sharma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4512.

Methods March 2024

An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model

PDF

Francesca Barone; Irina Bunea; Kristi Creel; Ruchi Sharma; Juan Amaral; Arvydas Maminishkis; Kapil Bharti
TAGS: animal model, suidae, training, vision, visual psychophysics
Trans. Vis. Sci. Tech.. 2024; 13(3):8. https://doi.org/10.1167/tvst.13.3.8

Includes: Multimedia, Supplemental Content

Optica Fall Vision Meeting Abstract December 2023

Invited Session II: Retinal remodeling and regeneration: Developing autologous iPSC-RPE therapy for the treatment of AMD patients

Ruchi Sharma; Kapil Bharti
TAGS: induced pluripotent stem cells
Journal of Vision. 2023; 23(15):9. https://doi.org/10.1167/jov.23.15.9

ARVO Annual Meeting Abstract June 2023

VLC-PUFA supplementation increases Elovanoid synthesis in a two-compartment Late-Onset Retinal Degeneration-iRPE model

Jeff Xiang Ji; Jorgelina Muriel Calandria; Megan Cothern; Rasangi Perera; Kapil Bharti; Kiyoharu Miyagishima; Ruchi Sharma; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5456.

ARVO Annual Meeting Abstract June 2023

In Vitro Dry-AMD Modeling using iPSC-derived Outer Blood Retinal Barrier Formed by RPE and 3D Bioprinted Choroid

Tea Soon Park; Russell Quinn; Rishabh Hirday; Amir Ali; Eric Nguyen; Devika Abhijit Bose; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5069.

ARVO Annual Meeting Abstract June 2023

TYROSINASE Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects

Arnold Leigh; Aman George; Tyler Pfister; Charles DeYoung; Ruchi Sharma; Mones Abu-Asab; Jizhong Zou; Kapil Bharti; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):775.

ARVO Annual Meeting Abstract June 2023

Stem cell-derived retinal co-grafts repair permanent retinal damage in a rat model of laser injury

Deepthi S. Rajendran Nair; Magdalene J Seiler; Juan Carlos Martinez; Ruchi Sharma; Kapil Bharti; Mark S Humayun; Biju B Thomas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1616.

ARVO Annual Meeting Abstract June 2023

Anaphylatoxins increase transposable element expression in human retinal pigment epithelium

Congxiao Zhang; Joys Annika David; David McGaughey; Andrew Fausey; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2093.

ARVO Annual Meeting Abstract June 2023

Piezo1 channels highly expressed in human RPE

Qin Wan; Joys Annika David; Congxiao Zhang; Tea Soon Park; Mitra Farnoodian; Eric Nguyen; Jair Montford; Colby Lewallen; Aman George; Kiyoharu Miyagishima; David McGaughey; Davide Ortolan; Devika Abhijit Bose; Arvydas Maminishkis; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2982.

ARVO Annual Meeting Abstract June 2023

Patient iPSC-derived Retinal Pigment Epithelium as a Model for Ciliopathy mediated Retinal Degenerations

Dominik Reichert; Davide Ortolan; Colby Lewallen; Helen May-Simera; Wadih M Zein; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3181.

ARVO Annual Meeting Abstract June 2023

Increased lysosome and autophagosome presence in OCA1A iPSC derived Retinal Pigment Epithelium

Aman George; Arnold Leigh; Mones Abu-Asab; Ruchi Sharma; Kapil Bharti; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3889.

ARVO Annual Meeting Abstract June 2023

Surgical approach for transplantation of a photoreceptor precursors patch in a swine Commotio Retinae model

Juan Amaral; Richard J Blanch; Irina Bunea; Ruchi Sharma; Jair Montford; Agustin Luz-Madrigal; Kimberly Lauren Edwards; Francesca Barone; Michael J Phillips; Arvydas Maminishkis; David M Gamm; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3713.

ARVO Annual Meeting Abstract June 2023

Multi-omics approach reveals metabolic switch in developing iPSC-derived RPE

Ruchi Sharma; Zander Esh; Davide Ortolan; Jair Montford; Jiwon Ryu; David McGaughey; Alan Jarmusch; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3514.

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