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Letters to the Editor March 2025

Author Response: Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?

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Patricia Barreto; Claudia Farinha; Rita Coimbra; Rufino Silva
TAGS: age-related macular degeneration, genetics, statins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):3. https://doi.org/10.1167/iovs.66.3.3

Genetics July 2024

ANO2 Genetic Variants and Anti-VEGF Treatment Response in Neovascular AMD: A Pharmacogenetic Substudy of VIEW 1 and VIEW 2

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Robyn H. Guymer; Rufino Silva; Mercedeh Ghadessi; Sergio Leal; Isabella Gashaw; Amy Damask; Charles Paulding; Kay D. Rittenhouse
TAGS: anti-vascular endothelial growth factor therapy, exudative age-related macular degeneration, genetics, genome-wide association study, pharmacogenetics, surrogate endpoints, single nucleotide polymorphism, candidate disease gene
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):17. https://doi.org/10.1167/iovs.65.8.17

Includes: Supplemental Content

Retina June 2024

Unveiling Statins and Genetics in Age-Related Macular Degeneration: The Coimbra Eye Study—Report 9

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Patrícia Barreto; Cláudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Yara Lechanteur; Carel B. Hoyng; José Cunha-Vaz; Rufino Silva
TAGS: age-related macular degeneration, eye, statins, genetics, study report
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):38. https://doi.org/10.1167/iovs.65.6.38

ARVO Annual Meeting Abstract June 2024

Aflibercept 8 mg monotherapy shows maintained efficacy over 96 weeks, with the ability to extend dosing intervals beyond every 16 weeks, in patients with PCV in the PULSAR Phase 3 trial

Rufino Silva; Tien Y Wong; Gemmy Cheung; Jeffrey S Heier; Won Ki Lee; Tomohiro Iida; xin Zhang; Tobias Machewitz; Andrea Schulze; Sergio Leal

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):219.

ARVO Annual Meeting Abstract June 2024

Exogenous Metabolites Associated with Age-related Macular Degeneration (AMD): A Cross-Sectional Study

Roshni Bhat; Ines Lains; Kevin Mendez; Krupa Sourirajan; Haemin Kang; Joao Gil; Rufino Silva; John B Miller; Ivana K Kim; Demetrios G. Vavvas; Jessica Lasky-Su; Joan W Miller; Deeba Husain

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1350.

ARVO Annual Meeting Abstract June 2024

Association between the genetic risk score and extramacular drusen in an age-related macular degeneration cohort - The Coimbra Eye Study

Rita Coimbra; Claudia Farinha; Patrícia Barreto; Maria da Luz Cachulo; José Cunha-Vaz; Yara Lechanteur; Carel C B Hoyng; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4389.

ARVO Annual Meeting Abstract June 2024

Uncovering statins with genetics in age-related macular degeneration

Patrícia Barreto; Claudia Farinha; Rita Coimbra; Maria da Luz Cachulo; Joana Melo; Carel C B Hoyng; Yara Lechanteur; José Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4355.

Retina May 2024

Age-Related Macular Degeneration and Extramacular Drusen: Genetic Associations in the Coimbra Eye Study

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Cláudia Farinha; Patrícia Barreto; Rita Coimbra; Maria Beatriz Machado; Inês Figueiredo; Maria Luz Cachulo; José Cunha-Vaz; Rufino Silva
TAGS: age-related macular degeneration, drusen, eye, genetics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):35. https://doi.org/10.1167/iovs.65.5.35

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

EYS -ASSOCIATED RETINAL DEGENERATION: NATURAL HISTORY, GENETIC LANDSCAPE AND PHENOTYPIC SPECTRUM

Ricardo Soares; Ana Luísa Carvalho; Sílvia Simão; Célia Azevedo Soares; Miguel Raimundo; Henrique Alves; António Francisco Ambrósio; Joaquim Murta; Jorge Saraiva; Rufino Silva; João Pedro Marques

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4663.

ARVO Annual Meeting Abstract June 2023

Exogenous Metabolites Associated with Age-related Macular Degeneration (AMD)

Ines Lains; Kevin Mendez; Joao Gil; Joana Providencia; Archana Nigalye; Raviv Katz; Patrícia Barreto; Rachel S Kelly; Ivana K Kim; John B Miller; Demetrios G. Vavvas; Jessica Lasky-Su; Rufino Silva; Joan W Miller; Deeba Husain

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2759.

Retina August 2022

Phenotypic Expression of CFH Rare Variants in Age-Related Macular Degeneration Patients in the Coimbra Eye Study

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Cláudia Farinha; Patrícia Barreto; Rita Coimbra; Adela Iutis; Maria Luz Cachulo; José Cunha-Vaz; Yara T. E. Lechanteur; Carel B. Hoyng; Rufino Silva
TAGS: age-related macular degeneration, eye, phenotype, drusen, genes, genetics
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):5. https://doi.org/10.1167/iovs.63.9.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration in Europeans: A meta-analysis of the European Eye Epidemiology (E3) – consortium

Matthias Marten Marten Mauschitz; Alexander Karl-Georg Schuster; Anthony P Khawaja; Mukharram Bikbov; Ruth E. Hogg; Franziska G Rauscher; Maja Gran Erke; Fotis Topouzis; Caroline Brandl; Catherine Creuzot-Garcher; Cecile Delcourt; Hans-Werner Hense; Rufino Silva; Stefano Piermarocchi; Karen Ritchie; Robert P Finger

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):378 – F0209.

ARVO Annual Meeting Abstract June 2022

Urinary Mass Spectrometry Metabolomic Profiles in Age-related Macular Degeneration (AMD)

Deeba Husain; Ines Lains; Kevin Milton Mendez; Joao Q Gil; rachel kelly; John B Miller; Demetrios G. Vavvas; Ivana K Kim; Joaquim Murta; Liming Liang; Rufino Silva; Jessica Lasky-Su; Joan W Miller

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):364 – F0195.

ARVO Annual Meeting Abstract June 2022

Association of genetics and the adherence to the Mediterranean diet: the risk for age-related macular degeneration

Patrícia Barreto; Claudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Carel C B Hoyng; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):346 – F0177.

ARVO Annual Meeting Abstract June 2022

Rare variants in CFH and phenotype in Age-related Macular Degeneration in the Coimbra Eye Study.

Claudia Farinha; Patrícia Barreto; Rita Coimbra; Adela Lutis; Maria Luz Cachulo; Jose G Cunha-Vaz; Yara T E Lechanteur; Carel C B Hoyng; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):330 – F0161.

ARVO Annual Meeting Abstract June 2022

Genetic variants in ANO2 may be predictive for treatment response to anti-VEGF in neovascular age-related macular degeneration

Robyn H Guymer; Rufino Silva; Mercedeh Ghadessi; Sergio Leal; Isabella Gashaw; Amy Damask; Charles Paulding; Kay D. Rittenhouse

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1495.

ARVO Annual Meeting Abstract June 2022

Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium

Alexander Karl-Georg Schuster; Joëlle Vergroesen; Kelsey Vernon Stuart; Geir Bertelsen; Fotis Topouzis; Mukharram Bikbov; Catherine Creuzot-Garcher; Cecile Delcourt; Rufino Silva; Nomdo M Jansonius; Franziska G Rauscher; Caroline C W Klaver; Norbert Pfeiffer; Wishal D Ramdas; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2267.

ARVO Annual Meeting Abstract June 2022

Automatic detection of drusen-like deposits on OCT using EfficientNet models

Luís Mendes; Thiago Martins; Paulo Schor; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2091 – F0080.

ARVO Annual Meeting Abstract June 2022

Plasma Metabolites Associated with Optical Coherence Tomography (OCT) Features of Age-related Macular Degeneration (AMD)

Ines Lains; Xikun Han; Joao Quadrado Gil; Joana Providencia; Archana Nigalye; Rodrigo Alvarez; Vivian Paraskevi Douglas; Rachel S Kelly; John B Miller; Demetrios G. Vavvas; Ivana K Kim; Rufino Silva; Jessica Lasky-Su; Joan W Miller; Deeba Husain

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3527.

ARVO Imaging in the Eye Conference Abstract August 2021

Automatic detection of pathological OCT volumes based on structural and OCTA metrics

Luís Mendes; Thiago Martins; Jose Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(11):17.

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Author Response: Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?

ANO2 Genetic Variants and Anti-VEGF Treatment Response in Neovascular AMD: A Pharmacogenetic Substudy of VIEW 1 and VIEW 2

Unveiling Statins and Genetics in Age-Related Macular Degeneration: The Coimbra Eye Study—Report 9

Aflibercept 8 mg monotherapy shows maintained efficacy over 96 weeks, with the ability to extend dosing intervals beyond every 16 weeks, in patients with PCV in the PULSAR Phase 3 trial

Exogenous Metabolites Associated with Age-related Macular Degeneration (AMD): A Cross-Sectional Study

Association between the genetic risk score and extramacular drusen in an age-related macular degeneration cohort - The Coimbra Eye Study

Uncovering statins with genetics in age-related macular degeneration

Age-Related Macular Degeneration and Extramacular Drusen: Genetic Associations in the Coimbra Eye Study

EYS -ASSOCIATED RETINAL DEGENERATION: NATURAL HISTORY, GENETIC LANDSCAPE AND PHENOTYPIC SPECTRUM

Exogenous Metabolites Associated with Age-related Macular Degeneration (AMD)

Phenotypic Expression of CFH Rare Variants in Age-Related Macular Degeneration Patients in the Coimbra Eye Study

Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration in Europeans: A meta-analysis of the European Eye Epidemiology (E3) – consortium

Urinary Mass Spectrometry Metabolomic Profiles in Age-related Macular Degeneration (AMD)

Association of genetics and the adherence to the Mediterranean diet: the risk for age-related macular degeneration

Rare variants in CFH and phenotype in Age-related Macular Degeneration in the Coimbra Eye Study.

Genetic variants in ANO2 may be predictive for treatment response to anti-VEGF in neovascular age-related macular degeneration

Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium

Automatic detection of drusen-like deposits on OCT using EfficientNet models

Plasma Metabolites Associated with Optical Coherence Tomography (OCT) Features of Age-related Macular Degeneration (AMD)

Automatic detection of pathological OCT volumes based on structural and OCTA metrics

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