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Retina September 2023

Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen

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Yevgeniy Sazhnyev; Tzu-Ni Sin; Anthony Ma; Ellie Chang; Leon Huynh; Karolina Roszak; Sangwan Park; Kevin Choy; Sina Farsiu; Ala Moshiri; Sara M. Thomasy; Glenn Yiu
TAGS: aging, drusen, macaca mulatta
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):44. https://doi.org/10.1167/iovs.64.12.44

Includes: Supplemental Content

Retina June 2023

Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques

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Elyse M. Salpeter; Ala Moshiri; Michelle Ferneding; Monica J. Motta; Sangwan Park; Chrisoula Skouritakis; Sara M. Thomasy
TAGS: macaca mulatta, pupillometry, retinal diseases, screening, dark adaptation
Trans. Vis. Sci. Tech.. 2023; 12(6):13. https://doi.org/10.1167/tvst.12.6.13

Includes: Supplemental Content

Cornea June 2023

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity

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Kenten D. Kingsbury; Jessica M. Skeie; Krista Cosert; Gregory A. Schmidt; Benjamin T. Aldrich; Christopher S. Sales; Julia Weller; Friedrich Kruse; Sara M. Thomasy; Ursula Schlötzer-Schrehardt; Mark A. Greiner
TAGS: body tissue, cornea, diabetes mellitus, diabetes mellitus, type 2, donors, muscle rigidity, proteins, tissue transplants, extracellular matrix, age
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):26. https://doi.org/10.1167/iovs.64.7.26

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

The role of epithelial membrane-associated mucin 4 ( Muc4 ) in ocular surface health and corneal wound healing

Sara Adelman; Melinda Quan; Erin Hisey; Christopher J Murphy; Sara M Thomasy; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):196.

ARVO Annual Meeting Abstract June 2023

Long-term safety and biocompatibility of a biodegradable, thermoresponsive aflibercept-loaded microsphere-hydrogel drug delivery system in nonhuman primates

Brett D Story; Sangwan Park; Karolina Roszak; Jaeho Shim; Monica Motta; Michelle Ferneding; Kayla M Rudeen; Glenn Yiu; William F Mieler; Sara M Thomasy; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):737.

ARVO Annual Meeting Abstract June 2023

Investigation of a novel rabbit nonpolar lipid for the treatment of evaporative dry eye disease in a murine model

Brian Leonard; Erin Hisey; Sangwan Park; Daniel M Albert; Charles O’Neill; Christopher J Murphy; Thomas R Gadek; Jennifer Y Li; Sara M Thomasy; Atul N Parikh

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):712.

ARVO Annual Meeting Abstract June 2023

Biophysical behaviors of meibum from mice with meibomian gland dysfunction

Erin Hisey; Tanner J Finney; Tonya L Kuhl; Daniel M Albert; Charles A O'Neill; Thomas R Gadek; Jennifer Y Li; Sangwan Park; Christopher J Murphy; Sara M Thomasy; Atul N Parikh; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):669.

ARVO Annual Meeting Abstract June 2023

Disease progression using multimodal corneal imaging in an early-onset murine model of FECD

Nayeli Echeverria; Sangwan Park; Jaeho Shim; Michelle Ferneding; Laura J Young; Jessica Skeie; Mark A Greiner; Sara M Thomasy; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):637.

ARVO Annual Meeting Abstract June 2023

Isoliquiritigenin inhibits corneal fibroblast to myofibroblast differentiation in vitro

Vanessa Rozo; Noah William Faber; Weinong Song; Rishi Sudhir; Liana Carino Williams; Jennifer Y Li; Sara M Thomasy; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1708.

ARVO Annual Meeting Abstract June 2023

Genome-wide association study of corneal endothelial dystrophy in Boston terriers with the addition of formalin-fixed paraffin embedded tissue samples

Laura J Young; M Isabel Casanova; Danika L Bannasch; Sangwan Park; Nayeli Echeverria; Morgan AW Bowman; Alyssa L Hoehn; Connor Chang; Michelle Ferneding; Brian Leonard; Kathryn L Good; Jennifer Y Li; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2778.

ARVO Annual Meeting Abstract June 2023

Quantification of optic nerve head structure using optical coherence tomography in dogs with glaucoma and retinal degeneration

Soohyun Kim; Michelle Ferneding; Sara Adelman; Bianca C Martins; Sara M Thomasy; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3437.

ARVO Annual Meeting Abstract June 2023

Impact of plasma lipid profile on soft drusen and drusenoid punctate lesions in nonhuman primate eyes.

Carol Iveth Villafuerte; Tzu-Ni Sin; Leon Huynh; Kevin Choy; Sina Farsiu; Ala Moshiri; Sara M Thomasy; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3338.

ARVO Annual Meeting Abstract June 2023

Safety and efficacy of CRISPR-based genome ablation of VEGFA as treatment for choroidal neovascularization in nonhuman primate eyes.

Tzu-Ni Sin; Carol Villafuerte-Trisolini; Sook Hyun Chung; Lien Tu; Sara M Thomasy; Ala Moshiri; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3257.

ARVO Annual Meeting Abstract June 2023

Single-cell transcriptomics of the murine cornea reveals novel age driven changes in gene expression, cell identity composition, and limbal trajectory

Raneesh Ramarapu; Sangwan Park; Nayeli Echeverria; Michelle Ferneding; Sophie M Le; Monica Ardon; Vijay Krishna Raghunathan; Crystal D Rogers; Brian Leonard; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3145.

ARVO Annual Meeting Abstract June 2023

A WHRN mutation in nonhuman primates alters ocular biometric parameters but not retinal structure or function

Jaeho Shim; Sangwan Park; Karolina Roszak; Kira H Lin; Sophie M Le; Monica Motta; Michelle Ferneding; Jun Wang; Marguerite F Knipe; Tim Stout; Jeffrey Rogers; Rui Chen; Ala Moshiri; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4190.

ARVO Annual Meeting Abstract June 2023

Multimodal corneal imaging to characterize a novel central stromal dystrophy in dog

Ana Cláudia Raposo; Sangwan Park; Sophie M Le; Michelle Ferneding; Elyse Salpeter; Bret Moore; Brian Leonard; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4037.

ARVO Annual Meeting Abstract June 2023

Chromatic Electroretinography in Non-human Primates with and without PDE6C-associated Achromatopsia

Monica Motta; Quentin Davis; Michelle Ferneding; Sangwan Park; Kira H Lin; Rui Chen; Jeffrey Rogers; Tim Stout; Sara M Thomasy; Ala Moshiri

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5228.

Cornea April 2023

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

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Brian C. Leonard; Sangwan Park; Soohyun Kim; Laura J. Young; Iman Jalilian; Krista Cosert; Xunzhi Zhang; Jessica M. Skeie; Hanna Shevalye; Nayeli Echeverria; Vanessa Rozo; Xin Gong; Chao Xing; Christopher J. Murphy; Mark A. Greiner; V. Vinod Mootha; Vijay Krishna Raghunathan; Sara M. Thomasy
TAGS: cornea, endothelium, hereditary corneal dystrophy, mice, signs and symptoms, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):22. https://doi.org/10.1167/iovs.64.4.22

Includes: Supplemental Content

Retina January 2023

A Spontaneous Nonhuman Primate Model of Myopic Foveoschisis

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Tzu-Ni Sin; Sangbae Kim; Yumei Li; Jun Wang; Rui Chen; Sook Hyun Chung; Soohyun Kim; M. Isabel Casanova; Sangwan Park; Zeljka Smit-McBride; Ning Sun; Ori Pomerantz; Jeffrey A. Roberts; Bin Guan; Robert B. Hufnagel; Ala Moshiri; Sara M. Thomasy; Paul A. Sieving; Glenn Yiu
TAGS: myopic foveoschisis, primates, genes, macaca mulatta, photoreceptors, diagnostic imaging, eye, cell nucleus, proteins, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):18. https://doi.org/10.1167/iovs.64.1.18

Includes: Supplemental Content

Genetics November 2022

Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

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Elangovan Boobalan; Amy H. Thompson; Ramakrishna P. Alur; David M. McGaughey; Lijin Dong; Grace Shih; Emile R. Vieta-Ferrer; Ighovie F. Onojafe; Vijay K. Kalaskar; Gavin Arno; Andrew J. Lotery; Bin Guan; Chelsea Bender; Omar Memon; Lauren Brinster; Clement Soleilhavoup; Lia Panman; Tudor C. Badea; Andrea Minella; Antonio Jacobo Lopez; Sara M. Thomasy; Ala Moshiri; Delphine Blain; Robert B. Hufnagel; Tiziana Cogliati; Kapil Bharti; Brian P. Brooks
TAGS: embryo, fissure, mice, optics, eye, transcription factor
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):5. https://doi.org/10.1167/iovs.63.12.5

Includes: Supplemental Content

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Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen

Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity

The role of epithelial membrane-associated mucin 4 ( Muc4 ) in ocular surface health and corneal wound healing

Long-term safety and biocompatibility of a biodegradable, thermoresponsive aflibercept-loaded microsphere-hydrogel drug delivery system in nonhuman primates

Investigation of a novel rabbit nonpolar lipid for the treatment of evaporative dry eye disease in a murine model

Biophysical behaviors of meibum from mice with meibomian gland dysfunction

Disease progression using multimodal corneal imaging in an early-onset murine model of FECD

Isoliquiritigenin inhibits corneal fibroblast to myofibroblast differentiation in vitro

Genome-wide association study of corneal endothelial dystrophy in Boston terriers with the addition of formalin-fixed paraffin embedded tissue samples

Quantification of optic nerve head structure using optical coherence tomography in dogs with glaucoma and retinal degeneration

Impact of plasma lipid profile on soft drusen and drusenoid punctate lesions in nonhuman primate eyes.

Safety and efficacy of CRISPR-based genome ablation of VEGFA as treatment for choroidal neovascularization in nonhuman primate eyes.

Single-cell transcriptomics of the murine cornea reveals novel age driven changes in gene expression, cell identity composition, and limbal trajectory

A WHRN mutation in nonhuman primates alters ocular biometric parameters but not retinal structure or function

Multimodal corneal imaging to characterize a novel central stromal dystrophy in dog

Chromatic Electroretinography in Non-human Primates with and without PDE6C-associated Achromatopsia

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

A Spontaneous Nonhuman Primate Model of Myopic Foveoschisis

Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

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