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ARVO Imaging in the Eye Conference Abstract July 2024

Hypertransmission defect phenotypes and functional associations in eyes with neovascular age-related macular degeneration

Siqing Yu; Bjoern Titz; Mahnaz Parian-Scherb; Isabel Bachmeier; Philip Enders; Lebriz Altay; Michael Koss; Siamak Ansari Shahrezaei; Justus Garweg; Carl Glittenberg; Cathy Cukras; Andreas Maunz; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB0082.

ARVO Imaging in the Eye Conference Abstract July 2024

Slab selection for effective en-face OCT segmentation of hypertransmission defects (hyperTD) in neovascular age-related macular degeneration (nAMD)

Mahnaz Parian-Scherb; Siqing Yu; Isabel Bachmeier; Philip Enders; Lebriz Altay; Michael Koss; Siamak Ansari Shahrezaei; Justus Garweg; Carl Glittenberg; Cathy Cukras; Sascha Fauser; Andreas Maunz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB0090.

ARVO Imaging in the Eye Conference Abstract July 2024

Model for resolution of subretinal hyperreflective material (SHRM) in neovascular age-related macular degeneration (nAMD) using deep learning (DL) image segmentation

Isabel Bachmeier; Siqing Yu; Carl Glittenberg; Andreas Maunz; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB009.

Retina June 2024

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

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Björn Titz; Juliane Siebourg-Polster; Francois Bartolo; Vincent Lavergne; Zhiwen Jiang; Javier Gayan; Lebriz Altay; Philip Enders; Christoph Schmelzeisen; Quynh-Trang Ippisch; Michael Janusz Koss; Siamak Ansari-Shahrezaei; Justus Gerhard Garweg; Sascha Fauser; Andreas Dieckmann
TAGS: aqueous humor, hypertension, mass or substance concentration per volume, proteins, retinal diseases, lens (device), lens, crystalline, metabolomics, phenylephrine
Trans. Vis. Sci. Tech.. 2024; 13(6):17. https://doi.org/10.1167/tvst.13.6.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Intravitreal interleukin-6 inhibition with vamikibart in sarcoidosis-associated uveitis

Meike Pauly-Evers; Zeinab Barekati; Federica Storti; William Holmes; Laura Steeples; Zdenka Haskova; Phoebe Lin; Sumit Sharma; Sascha Fauser; Marina Mesquida

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2611.

ARVO Annual Meeting Abstract June 2024

Volumetric fluid dynamics using machine-learning augmented analysis in patients with uveitic macular edema receiving vamikibart in the DOVETAIL study

Karen Matar; Yavuz Cakir; Hasan Cetin; Reem Amine; Michelle Bonnay; Conor Anthony Mcconville; Sunil K Srivastava; Meike Pauly-Evers; Zeinab Barekati; Federica Storti; Sumit Sharma; Sascha Fauser; Marina Mesquida; Justis Ehlers

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3029.

ARVO Annual Meeting Abstract June 2024

Longitudinal quantitative ultra-widefield fluorescein angiography leakage dynamics in patients with uveitic macular edema following intravitreal anti–IL-6 therapy with vamikibart

Yavuz Cakir; Karen Matar; Hasan Cetin; Reem Amine; Michelle Bonnay; Conor Anthony Mcconville; Sunil K Srivastava; Meike Pauly-Evers; Zeinab Barekati; Federica Storti; Sumit Sharma; Sascha Fauser; Marina Mesquida; Justis Ehlers

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2628.

ARVO Annual Meeting Abstract June 2024

Longitudinal Quantitative Anterior Chamber Cell Analysis Following Vamikibart Intravitreal Therapy in Patients with Uveitic Macular Edema from the DOVETAIL Clinical Trial

Sumit Sharma; Abel Hamden; Cindy Chen; Sandeep Singh; Phuoc-Hanh Le; Kimberly Baynes; Meike Pauly-Evers; Zeinab Barekati; Federica Storti; Sascha Fauser; Marina Mesquida; Sunil K Srivastava

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3028.

ARVO Annual Meeting Abstract June 2024

Aqueous humor interleukin-6 levels in uveitic macular edema: baseline characteristics from the phase 1 DOVETAIL study

Zeinab Barekati; William Holmes; Tamara von Donge; Meike Pauly-Evers; Robbie Peck; Daniela Willen; Benedicte Passemard; Sascha Fauser; Marina Mesquida; Federica Storti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3021.

Clinical and Epidemiologic Research May 2024

Intraretinal Hyper-Reflective Foci Are Almost Universally Present and Co-Localize With Intraretinal Fluid in Diabetic Macular Edema

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Esther L. von Schulthess; Andreas Maunz; Usha Chakravarthy; Nancy Holekamp; Daniel Pauleikhoff; Katie Patel; Isabel Bachmeier; Siqing Yu; Yaniv Cohen; Mahnaz Parian Scherb; Ian L. Jones; Kara Gibson; Jeffrey R. Willis; Carl Glittenberg; Rishi P. Singh; Sascha Fauser
TAGS: diabetic macular edema, face, retina, severity of illness, spectral domain-optical coherence tomography, volume
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):26. https://doi.org/10.1167/iovs.65.5.26

Includes: Supplemental Content

Genetics November 2023

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration

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Ilhan E. Acar; Tessel E. Galesloot; Ulrich F. O. Luhmann; Sascha Fauser; Javier Gayán; Anneke I. den Hollander; Everson Nogoceke
TAGS: age-related macular degeneration, genes, genome, whole genome sequencing, asthma
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):24. https://doi.org/10.1167/iovs.64.14.24

Includes: Supplemental Content

Retina November 2023

Correlation of Aqueous, Vitreous, and Serum Protein Levels in Patients With Retinal Diseases

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Sabine Wilson; Juliane Siebourg-Polster; Bjoern Titz; Zhiwen Jiang; Francois Bartolo; Vincent Lavergne; Javier Gayán; Justus G. Garweg; Sascha Fauser; Andreas Dieckmann
TAGS: biological markers, hypertension, proteins, retinal diseases, vitreous body, aqueous humor
Trans. Vis. Sci. Tech.. 2023; 12(11):9. https://doi.org/10.1167/tvst.12.11.9

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract June 2023

3D meshing and unbiased Compute Unified Device Architecture ray-traced contour rendering of convolutional neural network segmentations of dense optical-coherence volumes in DME and nAMD

Carl Glittenberg; Andreas Maunz; Esther von Schulthess; Isabel Bachmeier; Ian Lloyd Jones; Yaniv Cohen; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PP0012.

ARVO Imaging in the Eye Conference Abstract June 2023

Automated Segmentation of Hyperreflective Foci in Diabetic Macular Edema shows Greater Volume Reduction by Faricimab vs Aflibercept in Phase 3 YOSEMITE and RHINE

Andreas Maunz; Esther von Schulthess; Katie M Patel; Usha Chakravarthy; Isabel Bachmeier; Ian Lloyd Jones; Yaniv Cohen; Kara Gibson; Jeffrey Willis; Carl Glittenberg; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0039.

ARVO Annual Meeting Abstract June 2023

A novel anti-IL-6 monoclonal antibody leads to restoration of IL-6-mediated endothelial barrier breakdown

Derrick Feenstra; Pamela Strassburger; Gabriella Widmer; Franco Revelant; Sabine Uhles; Marlon Hinner; Anastasia Meier; Mirjana Lazendic; Sabine Gruener; Sascha Fauser; Marina Mesquida

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5189.

ARVO Annual Meeting Abstract June 2023

A novel intravitreal anti-IL-6 monoclonal antibody for uveitic macular edema (UME): preliminary results from the phase 1 DOVETAIL study

Sumit Sharma; Eric Suhler; Phoebe Lin; Meike Pauly-Evers; Daniela Willen; Robbie Peck; Federica Storti; Simone Rauhut; Tatiana Gott; Benedicte Passemard; Lachlan Macgregor; Zdenka Haskova; David Silverman; Sascha Fauser; Marina Mesquida

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5100.

ARVO Annual Meeting Abstract June 2022

Safety and efficacy of fovea-involving half-dose photodynamic therapy for chronic central serous chorioretinopathy

Helena Margaret Anthonia Feenstra; Roselie M.H. Diederen; Martine J.C.M. Lamme; Sascha Fauser; Susan M. Downes; Reinier O. Schlingemann; Carel C B Hoyng; Elon H.C. van Dijk; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):37.

ARVO Annual Meeting Abstract June 2021

Systemic Antisense Oligonucleotide Inhibition of Complement Factor B for Treatment of Geographic Atrophy: Results of a Placebo-controlled Phase 1 Dose-Escalation Study

David S Boyer; Jayashree Sahni; Sascha Fauser; Richard Geary; Eugene Schneider; Michael McCaleb

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):196.

Genetics December 2020

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

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Tina Schick; Laura Lorés-Motta; Lebriz Altay; Lars G. Fritsche; Anneke I. den Hollander; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):17. https://doi.org/10.1167/iovs.61.14.17

Includes: Supplemental Content

Articles August 2020

Tear Proteomic Predictive Biomarker Model for Ocular Graft Versus Host Disease Classification

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Olivia E. O'Leary; Andreas Schoetzau; Ludovic Amruthalingam; Nadine Geber-Hollbach; Kim Plattner; Paul Jenoe; Alexander Schmidt; Christoph Ullmer; Faye M. Drawnel; Sascha Fauser; Hendrik P. N. Scholl; Jakob Passweg; Joerg P. Halter; David Goldblum
TAGS: biological markers, graft-versus-host disease, proteins
Trans. Vis. Sci. Tech.. 2020; 9(9):3. https://doi.org/10.1167/tvst.9.9.3

Includes: Supplemental Content

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Hypertransmission defect phenotypes and functional associations in eyes with neovascular age-related macular degeneration

Slab selection for effective en-face OCT segmentation of hypertransmission defects (hyperTD) in neovascular age-related macular degeneration (nAMD)

Model for resolution of subretinal hyperreflective material (SHRM) in neovascular age-related macular degeneration (nAMD) using deep learning (DL) image segmentation

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

Intravitreal interleukin-6 inhibition with vamikibart in sarcoidosis-associated uveitis

Volumetric fluid dynamics using machine-learning augmented analysis in patients with uveitic macular edema receiving vamikibart in the DOVETAIL study

Longitudinal quantitative ultra-widefield fluorescein angiography leakage dynamics in patients with uveitic macular edema following intravitreal anti–IL-6 therapy with vamikibart

Longitudinal Quantitative Anterior Chamber Cell Analysis Following Vamikibart Intravitreal Therapy in Patients with Uveitic Macular Edema from the DOVETAIL Clinical Trial

Aqueous humor interleukin-6 levels in uveitic macular edema: baseline characteristics from the phase 1 DOVETAIL study

Intraretinal Hyper-Reflective Foci Are Almost Universally Present and Co-Localize With Intraretinal Fluid in Diabetic Macular Edema

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration

Correlation of Aqueous, Vitreous, and Serum Protein Levels in Patients With Retinal Diseases

3D meshing and unbiased Compute Unified Device Architecture ray-traced contour rendering of convolutional neural network segmentations of dense optical-coherence volumes in DME and nAMD

Automated Segmentation of Hyperreflective Foci in Diabetic Macular Edema shows Greater Volume Reduction by Faricimab vs Aflibercept in Phase 3 YOSEMITE and RHINE

A novel anti-IL-6 monoclonal antibody leads to restoration of IL-6-mediated endothelial barrier breakdown

A novel intravitreal anti-IL-6 monoclonal antibody for uveitic macular edema (UME): preliminary results from the phase 1 DOVETAIL study

Safety and efficacy of fovea-involving half-dose photodynamic therapy for chronic central serous chorioretinopathy

Systemic Antisense Oligonucleotide Inhibition of Complement Factor B for Treatment of Geographic Atrophy: Results of a Placebo-controlled Phase 1 Dose-Escalation Study

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

Tear Proteomic Predictive Biomarker Model for Ocular Graft Versus Host Disease Classification

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