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Review January 2022

Vision Restoration by Optogenetic Therapy and Developments Toward Sonogenetic Therapy

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Matthieu Provansal; Katia Marazova; José Alain Sahel; Serge Picaud
TAGS: optogenetics, vision
Trans. Vis. Sci. Tech.. 2022; 11(1):18. doi: https://doi.org/10.1167/tvst.11.1.18

ARVO Annual Meeting Abstract June 2021

3D visualization of human retina cells’ anatomy using expansion microscopy

Leyna Boucherit; Anna Verschueren; Marie Darche; Serge A Picaud; Jose Alain Sahel; Michel Paques

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3025. doi:

Lens September 2020

Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

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Vincent Lhussiez; Elisabeth Dubus; Quénol Cesar; Niyazi Acar; Emeline F. Nandrot; Manuel Simonutti; Isabelle Audo; Eléonore Lizé; Sylvie Nguyen; Audrey Geissler; André Bouchot; Muhammad Ansar; Serge Picaud; Christel Thauvin-Robinet; Laurence Olivier-Faivre; Laurence Duplomb; Romain Da Costa
TAGS: cataract, lens (device), lens, crystalline, genetic aspects, cohen syndrome, mice, syndrome, homeostasis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):18. doi: https://doi.org/10.1167/iovs.61.11.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

High resolution of primate and human photoreceptors' structure using Expansion microscopy.

VERSCHUEREN Anna; Leyna Boucherit; Marie Darche; Stephane Fouquet; Celine Nouvel-Jaillard; Michel Paques; Serge A Picaud; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):817. doi:

OSA Fall Vision Meeting Abstract July 2019

Visual restoration by an infrared photovoltaic implant and by optogenetic therapy: validation in non-human primates

Paul-Henri Prévot; Gregory Gauvain; Himanshu Akolkar; Mina A. Khoei; Kevin Gehere; Yannick LeMer; Claire-Maëlle Fovet; Philippe Hantraye; Stéphane Bertin; Elena Brazhnikova; Céline Nouvel-Jaillard; Jens Duebel; Deniz Dalkara; Pierre Pouget; José-Alain Sahel; Ryad Benosman; Serge Picaud

Journal of Vision. 2019; 19(8):48. doi: https://doi.org/10.1167/19.8.48

ARVO Annual Meeting Abstract July 2018

in vitro photoprotective effect of optical filters on retinal pigment epithelium cells exposed to moderate daylight-mimicking conditions

Melanie MARIE; Coralie Barrau; Camille EHRISMANN; Pauline GONDOUIN; Jose A. Sahel; Thierry Villette; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):598. doi:

ARVO Annual Meeting Abstract July 2018

Pointillism in the retina: a new method to semi-automaticly assess rods and cones density in immunostained retinas.

Anna Verschueren; valerie fradot; Serge A Picaud; José Alain SAHEL

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):604. doi:

Retina March 2018

Taurine Depletion Causes ipRGC Loss and Increases Light-Induced Photoreceptor Degeneration

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Diego García-Ayuso; Johnny Di Pierdomenico; Wahiba Hadj-Said; Mélanie Marie; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Serge Picaud; María P. Villegas-Pérez
TAGS: retinal degeneration, taurine, tissue degeneration, retinal cone, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1396-1409. doi: https://doi.org/10.1167/iovs.17-23258

ARVO Annual Meeting Abstract June 2017

The effect of light exposure in the population of different retinal neurons under taurine depletion

Diego Garcia-Ayuso; Johnny Di Pierdomenico; Wahiba Hadj Said; Melanie MARIE; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Serge A Picaud; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):290. doi:

ARVO Annual Meeting Abstract June 2017

Blue light decreases VEGF in an in vitro model of AMD

Melanie MARIE; Pauline GONDOUIN; Coralie BARRAU; Thierry VILLETTE; Denis COHEN-TANNOUDJI; Jose Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5859. doi:

ARVO Annual Meeting Abstract June 2017

Taurine deficiency induces retinal inflammation

Wahiba Hadj Said; Élisabeth Dubus; Stéphane Fouquet; Sauleine Sanglier; Diego Garcia-Ayuso; Maria Paz Villegas-Perez; Jose Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5870. doi:

ARVO Annual Meeting Abstract June 2017

Modeling the dynamics of light-driven microbial opsin ChrimsonR

Quentin Sabatier; Gregory Gauvain; Corentin Joffrois; Pierre M Daye; Joël Chavas; José Alain sahel; Didier Pruneau; Serge A Picaud; Ryad Benosman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5873. doi:

ARVO Annual Meeting Abstract June 2017

Visual acuity and optical flow in primate retinal ganglion cells treated with an optogenetic vision restoration strategy using ChrimsonR

Himanshu Akolkar; Gregory Gauvain; Romain Caplette; Deniz Dalkara; Celine Jaillard; Jose Alain Sahel; Didier Pruneau; Serge A Picaud; Ryad Benosman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5883. doi:

ARVO Annual Meeting Abstract June 2017

Long term visual restoration using optogenetic engineering of retinal ganglion cells with AAV2.7m8- ChrimsonR-tdTomato

Gregory Gauvain; Romain Caplette; Himanshu Akolkar; Celine Jaillard; Didier Pruneau; José Alain sahel; Deniz Dalkara; Ryad Benosman; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1219. doi:

ARVO Annual Meeting Abstract June 2017

Advanced Neural Circuit Analysis by Combining High-Resolution Optogenetic Stimulation, Two-Photon Imaging and Electrophysiology

Elric Esposito; Giulia Spampinato; Pierre Yger; Deniz Dalkara; Emiliano Ronzitti; Eirini Papagiakoumou; Valentina Emiliani; Serge A Picaud; Olivier Marre; Jens Duebel

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2586. doi:

ARVO Annual Meeting Abstract June 2017

Functional ultrasound imaging maps the visual system in rodents with high spatial and temporal precisions.

Kévin BLAIZE; Marc Gesnik; Thomas Deffieux; Jean-Luc Gennisson; Jose Alain Sahel; mathias fink; Mickaël Tanter; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3098. doi:

ARVO Annual Meeting Abstract June 2017

Behavioral and electrophysiological characterization of photovoltaic subretinal implants in non-human primates

Paul-Henri PREVOT; Marion Lanoë; Sami Dalouz; Kévin BLAIZE; Omar Oubari; Kevin Gehere; Himanshu Akolkar; Guillaume Buc; Serge A Picaud; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4270. doi:

Visual Neuroscience March 2017

LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells

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Marion Neuillé; Yan Cao; Romain Caplette; Debbie Guerrero-Given; Connon Thomas; Naomi Kamasawa; José-Alain Sahel; Christian P. Hamel; Isabelle Audo; Serge Picaud; Kirill A. Martemyanov; Christina Zeitz
TAGS: mice, retinal bipolar cells, retinal cone, synapses, synaptic transmission, rod photoreceptors, retina, dendrites, biopharmaceutics classification system, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1768-1778. doi: https://doi.org/10.1167/iovs.16-20745

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Optogenetic visual restoration using ChrimsonR: Photoactivation below safety radiation limit in retinal ganglion cell populations from non-human primates

Gregory Gauvain; Romain Caplette; Céline Jaillard; Antoine J Chaffiol; Melissa Desrosiers; Olivier Marre; Deniz Dalkara; José-Alain Sahel; Anne Douar; Didier Pruneau; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):598. doi:

ARVO Annual Meeting Abstract September 2016

Optogenetic visual restoration using ChrimsonR: Validation in degenerative rodent models, rd1 and P23H.

Romain Caplette; Elisabeth Dubus; Gregory Gauvain; Olivier Marre; Melissa Desrosiers; Deniz Dalkara; José-Alain Sahel; Anne Douar; Didier Pruneau; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):600. doi:

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Vision Restoration by Optogenetic Therapy and Developments Toward Sonogenetic Therapy

3D visualization of human retina cells’ anatomy using expansion microscopy

Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

High resolution of primate and human photoreceptors' structure using Expansion microscopy.

Visual restoration by an infrared photovoltaic implant and by optogenetic therapy: validation in non-human primates

in vitro photoprotective effect of optical filters on retinal pigment epithelium cells exposed to moderate daylight-mimicking conditions

Pointillism in the retina: a new method to semi-automaticly assess rods and cones density in immunostained retinas.

Taurine Depletion Causes ipRGC Loss and Increases Light-Induced Photoreceptor Degeneration

The effect of light exposure in the population of different retinal neurons under taurine depletion

Blue light decreases VEGF in an in vitro model of AMD

Taurine deficiency induces retinal inflammation

Modeling the dynamics of light-driven microbial opsin ChrimsonR

Visual acuity and optical flow in primate retinal ganglion cells treated with an optogenetic vision restoration strategy using ChrimsonR

Long term visual restoration using optogenetic engineering of retinal ganglion cells with AAV2.7m8- ChrimsonR-tdTomato

Advanced Neural Circuit Analysis by Combining High-Resolution Optogenetic Stimulation, Two-Photon Imaging and Electrophysiology

Functional ultrasound imaging maps the visual system in rodents with high spatial and temporal precisions.

Behavioral and electrophysiological characterization of photovoltaic subretinal implants in non-human primates

LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells

Optogenetic visual restoration using ChrimsonR: Photoactivation below safety radiation limit in retinal ganglion cell populations from non-human primates

Optogenetic visual restoration using ChrimsonR: Validation in degenerative rodent models, rd1 and P23H.

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