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ARVO Annual Meeting Abstract June 2024

Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Sarbodeep Paul; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Bruce Stevens; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):844.

ARVO Annual Meeting Abstract June 2024

Oral alpha-cyclodextrin targets the gut-retinal axis and corrects diabetic retinopathy (DR) in a mouse model of type 2 diabetes (T2D).

Yvonne Adu-Agyeiwaah; Ram Prasad; Sergio Li Calzi; Bright Asare Bediako; Jason Floyd; Mariana D Dupont; Tim Florian Dorweiler; Cristiano Vieira; Irina A Pikuleva; Julia Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):836.

ARVO Annual Meeting Abstract June 2024

The calvarium bone marrow responds to acute retinal injury and is resilient to chronic diabetes compared to long bone marrow.

Sergio Li Calzi; Bright Asare-Bediako; Ram Prasad; Yvonne Adu-Agyeiwaah; Robert F Rosencrans; Jason Floyd; Denise Stanford; Anna Lin; Todd A Lydic; Michael Boulton; Julia Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):325.

ARVO Annual Meeting Abstract June 2024

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

Sarbodeep Paul; Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):323.

ARVO Annual Meeting Abstract June 2024

Intraocular bioerodible implant of carboxyamidotriazole in rabbit models of proliferative retinopathy

Ayaka Fujihashi; Sergio Li Calzi; Yvonne Adu-Agyeiwaah; Bob Katz; Alan Franklin; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):209.

ARVO Annual Meeting Abstract June 2023

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Ram Prasad; Jason Floyd; Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Sergio Li Calzi; Dibyendu Chakraborty; Angela Harbour; Aayush Rohella; Irina A Pikuleva; Julia V. Busik; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):938.

ARVO Annual Meeting Abstract June 2023

Human iPSC derived CD34 + cells and endothelial colony-forming cells (ECFCs) correct diabetic retinopathy (DR) in a model of type 2 diabetes

Yazen Shihab; Sergio Li Calzi; Yvonne Adu-Agyeiwaah; Cristiano Vieira; Michael E. Boulton; Carolina Francelin Rovarotto; Matt George; Dave Mann; Mervin C. Yoder; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1307.

ARVO Annual Meeting Abstract June 2023

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Cristiano Vieira; Ram Prasad; Sergio Li Calzi; Irina A Pikuleva; Julia V. Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1834.

ARVO Annual Meeting Abstract June 2023

Calvarium bone marrow is the source of bone marrow-derived cells that migrate into the injured retina

Sergio Li Calzi; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Ram Prasad; Julia V. Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3866.

Retina April 2023

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

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Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sergio Li Calzi; Mariana DuPont; Jason Floyd; Sanford Boye; Vince Chiodo; Julia V. Busik; Maria B. Grant
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, intravitreal injections, mice, retina, blood capillaries, inflammation, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(4):20. https://doi.org/10.1167/tvst.12.4.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Correction of diabetic retinopathy by mitochondrial transfer

Denis A Proshlyakov; Sandra S Hammer; Sergio Li Calzi; Tim Florian Dorweiler; Cristiano P. Vieira; Kiera Fisher; Shari Atilano; M.Cristina Kenney; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):791 – F0350.

ARVO Annual Meeting Abstract June 2022

Intravitreal administration of AAV2-SIRT1 reverses diabetic retinopathy (DR) in a murine model of type 2 diabetes (T2D)

Maria B Grant; Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sandra S Hammer; Sergio Li Calzi; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2310.

ARVO Annual Meeting Abstract June 2022

DIFFERENTIAL RECUITMENT OF HEMATOPOIETIC CELLS INTO THE INJURED RPE/CHOROID

Bright Asare-Bediako; Sergio Li Calzi; Yvonne Adu-Agyeiwaah; Jason Floyd; Mariana D DuPont; Maria Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3025 – F0396.

ARVO Annual Meeting Abstract June 2022

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Yvonne Adu-Agyeiwaah; Sandra S Hammer; Cristiano P. Vieira; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Ram Prasad; Sergio Li Calzi; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3591 – A0046.

ARVO Annual Meeting Abstract June 2021

Intravitreal AAV2-SIRT1 administration reverses diabetic retinopathy in db/db mice

Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sandra S Hammer; Sergio Li Calzi; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1106.

ARVO Annual Meeting Abstract June 2021

Statins and α cyclodextrin treatments prevent cholesterol crystal-induced pathology in human retinal endothelial cells and in db/db mice.

Sandra S Hammer; Delaney McFarland; George Abela; Sergio Li Calzi; Maria B Grant; Julia V Busik

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2928.

ARVO Annual Meeting Abstract June 2020

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

Ram Prasad; Jason L. Floyd; DIBYENDU CHAKRABORTY; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Sergio Li Calzi; Robert F. Rosencrans; Chao Huang; Mariana DuPont; Sunil K Noothi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1169.

ARVO Annual Meeting Abstract June 2020

LXR activation prevents development of diabetic retinopathy (DR) in db/db mice by controlling cholesterol and stem cell profiles

Yvonne Adu-Agyeiwaah; Cristiano P Vieira; Ana Leda Longhini; Bright Asare-Bediako; Micheli Sielski; Mariana DuPont; Sergio Li Calzi; Julia Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5161.

ARVO Annual Meeting Abstract July 2019

TRIB3 ablation attenuates hypoxia-induced angiogenesis in mouse retinas

Priyamvada M Pitale; Yvonne Adu-Agyeiwaah; Sergio Li Calzi; Takashi Satoh; Shizuo Akira; Maria B Grant; Marina S Gorbatyuk

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6428.

ARVO Annual Meeting Abstract July 2019

Altered Circadian Metabolites in Type 2 Diabetic Mice with Diabetic Retinopathy

Samantha Prabakaran; Eleni Beli; Yaqian Duan; Sergio Li Calzi; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2672.

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Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

Oral alpha-cyclodextrin targets the gut-retinal axis and corrects diabetic retinopathy (DR) in a mouse model of type 2 diabetes (T2D).

The calvarium bone marrow responds to acute retinal injury and is resilient to chronic diabetes compared to long bone marrow.

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

Intraocular bioerodible implant of carboxyamidotriazole in rabbit models of proliferative retinopathy

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Human iPSC derived CD34 + cells and endothelial colony-forming cells (ECFCs) correct diabetic retinopathy (DR) in a model of type 2 diabetes

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Calvarium bone marrow is the source of bone marrow-derived cells that migrate into the injured retina

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

Correction of diabetic retinopathy by mitochondrial transfer

Intravitreal administration of AAV2-SIRT1 reverses diabetic retinopathy (DR) in a murine model of type 2 diabetes (T2D)

DIFFERENTIAL RECUITMENT OF HEMATOPOIETIC CELLS INTO THE INJURED RPE/CHOROID

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Intravitreal AAV2-SIRT1 administration reverses diabetic retinopathy in db/db mice

Statins and α cyclodextrin treatments prevent cholesterol crystal-induced pathology in human retinal endothelial cells and in db/db mice.

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

LXR activation prevents development of diabetic retinopathy (DR) in db/db mice by controlling cholesterol and stem cell profiles

TRIB3 ablation attenuates hypoxia-induced angiogenesis in mouse retinas

Altered Circadian Metabolites in Type 2 Diabetic Mice with Diabetic Retinopathy

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