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Articles August 2021

Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration

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Jing-Yan Yang; Bin Lu; Qiang Feng; Jorge S. Alfaro; Po-Hsuen Chen; Joseph Loscalzo; Wen-Bin Wei; Ying-Yi Zhang; Shi-Jiang Lu; Shaomei Wang
TAGS: ciliary neurotrophic factor, nerve growth factors, retinal degeneration, neuroprotection
Trans. Vis. Sci. Tech.. 2021; 10(9):6. https://doi.org/10.1167/tvst.10.9.6

ARVO Annual Meeting Abstract July 2019

Long term safety and efficacy of gene editing by CRISPR/Cas9 in autosomal dominant mutation model for RP

Shaomei Wang; Benjamin Bakondi; Bin Lu; Augustus Mercado; Yueqin zhou; Sergey Girman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2925.

ARVO Annual Meeting Abstract July 2019

Retinal preservation following lateral ventricle injection of AAV9-Cln6 into mouse model for Batten disease

Bin Lu; B Meyerink; K A White; J M Weimer; C N Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3418.

ARVO Annual Meeting Abstract July 2019

Sustainable protection of retinal degeneration in a rodent model for RP by stable and biocompatible nanoparticle-neurotrophic factor complexes

Shi-Jiang Lu; Bin Lu; Qiang Feng; Augustus Mercado; Yingyi Zhang; Joseph Loscalzo; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5707.

ARVO Annual Meeting Abstract July 2018

MSC-Exo as adjuvant potentiate vision preservation following subretinal injection of neural progenitor cells

Shaomei Wang; Bin Lu; Sergey Girman; changqing Zhang; Melissa Jones; Zhaohui Chen; Benjamin Bakondi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5010.

ARVO Annual Meeting Abstract July 2018

Validating the efficacy of GMP-NPCs following subretinal injection into an animal model of retinal degeneration

Bin Lu; Sergey Girman; Changqing Zhang; Joshua Saylor; Alice Pieplow; Sean Ghiam; Benjamin Bakondi; Amanda Block; Laura Nocito-Labad; Alexander V Ljubimov; Clive N Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):551.

ARVO Annual Meeting Abstract June 2017

Synergistic protection from retinal degeneration by Combined stem cell therapies

Shaomei Wang; Changqing Zhang; bin lu; Sergey Girman; Benjamin Bakondi; Joshua Saylor; Zhaohui chen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4550.

ARVO Annual Meeting Abstract September 2016

Human neural progenitor cell treatment modulates phagocytosis signaling in a rodent model for retinal degeneration

Melissa Kaye Jones; Bin Lu; Mehrnoosh Saghizadeh; Clive Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5316.

ARVO Annual Meeting Abstract June 2015

CRISPR/CAS9-Mediated In Vivo Gene Editing Corrects The Retinal Dystrophy Phenotype of S334ter-3 Rats.

Benjamin Bakondi; Wenjian Lv; Bin Lu; sergey Girman; YuChun Tsai; Aslam Akhtar; Rachelle Levy; Joshua Breunig; Clive Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3183.

ARVO Annual Meeting Abstract June 2015

Gene and protein expression changes following human neural progenitor cell injection into a retinal degeneration rodent model

Melissa Kaye Jones; Bin Lu; Mehrnoosh Saghizadeh; Neil Bhowmick; Clive Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3599.

ARVO Annual Meeting Abstract June 2015

Non-invasive administration of MSCs preserves vision in rodent model for retinal degeneration

Shaomei Wang; Bin Lu; YuChun Tsai; sergey Girman; Lin Shen; Benjamin Bakondi

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3602.

ARVO Annual Meeting Abstract June 2015

Survival and efficacy of xenogeneic cell transplants in the RCS rat in the absence of immunosuppression

Trevor J McGill; Shaomei Wang; Bin Lu; Stephen Huhn; Raymond D Lund; Alexandra Capela

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2357.

Articles February 2015

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy

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B.n. Lu; Yanhua Lin; Yuchun Tsai; Sergey Girman; Grazyna Adamus; Melissa K. Jones; Brandon Shelley; Clive N. Svendsen; Shaomei Wang
TAGS: retina, transplantation, eye, graft survival, vision, rats, photoreceptors, tissue transplants, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2015; 4(1):7. https://doi.org/10.1167/tvst.4.1.7

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Is Mesenchymal Stem Cell Homing To The Injured Retina Required For Visual Preservation In The RCS Rat?

Benjamin Bakondi; YuChun Tsai; Bin Lu; Sergey Girman; Lin Shen; Melissa Kaye Jones; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1377.

ARVO Annual Meeting Abstract April 2014

Systemic administration of MSCs preserves RGC survival after optic nerve crush

Shaomei Wang; YuChun Tsai; Benjamin Bakondi; Sergey Girman; Lin Shen; Bin Lu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2440.

ARVO Annual Meeting Abstract April 2014

In vivo study of neural progenitors after injection into a retinal degeneration rodent model

Melissa Kaye Jones; Bin Lu; Sergey Girman; YuChun Tsai; Benjamin Bakondi; Brandon Shelley; Alexander V Ljubimov; Clive Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4389.

ARVO Annual Meeting Abstract April 2014

Human iPSC-derived neural progenitor cells preserve vision in a rat retinal degeneration model

YuChun Tsai; Bin Lu; Sergey Girman; Benjamin Bakondi; Melissa Kaye Jones; Anais Sahabian; Dhruv Sareen; Clive Svendsen; Shaomei Wang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3978.

Anatomy and Pathology/Oncology January 2014

Ocular Changes in TgF344-AD Rat Model of Alzheimer's Disease

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Yuchun Tsai; Bin Lu; Alexander V. Ljubimov; Sergey Girman; Fred N. Ross-Cisneros; Alfredo A. Sadun; Clive N. Svendsen; Robert M. Cohen; Shaomei Wang
TAGS: alzheimer's disease, antibodies, choroid, eye, rats, retina, retinal pigment cell, brain, visual acuity, vision
Invest. Ophthalmol. Vis. Sci.. 2014; 55(1):523-534. https://doi.org/10.1167/iovs.13-12888

Includes: Supplemental Content

Translational Research October 2013

Phagocytosis of Photoreceptor Outer Segments by Transplanted Human Neural Stem Cells as a Neuroprotective Mechanism in Retinal Degeneration

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Nicolás Cuenca; Laura Fernández-Sánchez; Trevor J. McGill; Bin Lu; Shaomei Wang; Raymond Lund; Stephen Huhn; Alexandra Capela
TAGS: neural stem cells, phagocytosis, photoreceptors, retinal degeneration, transplantation, retina, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6745-6756. https://doi.org/10.1167/iovs.13-12860

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Translational development of human retinal progenitor cells for treatment of retinitis pigmentosa

Jing Yang; Geoffrey Lewis; Bin Lu; Nikolay Turovets; Gabriel Luna; Sergey Girman; Gerhard Bauer; Steven Fisher; Shaomei Wang; Henry Klassen

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2237.

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Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration

Long term safety and efficacy of gene editing by CRISPR/Cas9 in autosomal dominant mutation model for RP

Retinal preservation following lateral ventricle injection of AAV9-Cln6 into mouse model for Batten disease

Sustainable protection of retinal degeneration in a rodent model for RP by stable and biocompatible nanoparticle-neurotrophic factor complexes

MSC-Exo as adjuvant potentiate vision preservation following subretinal injection of neural progenitor cells

Validating the efficacy of GMP-NPCs following subretinal injection into an animal model of retinal degeneration

Synergistic protection from retinal degeneration by Combined stem cell therapies

Human neural progenitor cell treatment modulates phagocytosis signaling in a rodent model for retinal degeneration

CRISPR/CAS9-Mediated In Vivo Gene Editing Corrects The Retinal Dystrophy Phenotype of S334ter-3 Rats.

Gene and protein expression changes following human neural progenitor cell injection into a retinal degeneration rodent model

Non-invasive administration of MSCs preserves vision in rodent model for retinal degeneration

Survival and efficacy of xenogeneic cell transplants in the RCS rat in the absence of immunosuppression

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy

Is Mesenchymal Stem Cell Homing To The Injured Retina Required For Visual Preservation In The RCS Rat?

Systemic administration of MSCs preserves RGC survival after optic nerve crush

In vivo study of neural progenitors after injection into a retinal degeneration rodent model

Human iPSC-derived neural progenitor cells preserve vision in a rat retinal degeneration model

Ocular Changes in TgF344-AD Rat Model of Alzheimer's Disease

Phagocytosis of Photoreceptor Outer Segments by Transplanted Human Neural Stem Cells as a Neuroprotective Mechanism in Retinal Degeneration

Translational development of human retinal progenitor cells for treatment of retinitis pigmentosa

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