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ARVO Annual Meeting Abstract June 2025

Localization of Polypoidal Choroidal Vasculopathy in Fluorescein Angiography using Semi-Supervised Deep Learning

Chia-Ling Tsai; Chung-Chien Lin; Shih-Jen Chen; Yu-Ning Tsao; Wei-Yang Lin

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1715.

ARVO Annual Meeting Abstract June 2025

Faricimab for Polypoidal Choroidal Vasculopathy: Week 16 Results From the Phase 3b/4 SALWEEN Trial

Junyeop Lee; Gemmy Cheung; Shih-Jen Chen; Tomohiro Iida; Adrian Hock Chaun Koh; Won Ki Lee; Paisan Ruamviboonsuk; Xiaodong Sun; Yasuo Yanagi; Ruobing Bai; Philippe Margaron; Anh Nguyen Duc; Timothy Y Y Lai

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1859.

ARVO Annual Meeting Abstract June 2025

Instrumenting Anatomy-sensible Models to Predict Individual Visual Acuity Loss From Layer-wise OCT-Angiography Vascular Morphology

Chang Kao-Jung; Shih-Jen Chen; Shih-Hwa Chiou

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3860.

ARVO Annual Meeting Abstract June 2025

Leveraging LLM Technology: Development of an AI-Powered Agent for Cataract Surgery Education and IOL Selection

Wei-Chieh Fang; Kao-Jung Chang; Sheng-Chu Chi; Kai-Jui Liu; Yu-Chen Meng; Tien-Fu Chen; Shih-Jen Chen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3947.

Retina April 2025

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

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Kao-Jung Chang; Ching-Yun Wang; Hsin-Yu Wu; Pei-Yu Weng; Chia-Hsin Lu; Wei Chiu; Wei-Chieh Fang; Chong-En Kao; Cheng-Yi Li; Yi-Ting Chung; Yu-Chun Chen; Ai-Ru Hsieh; Shih-Hwa Chiou; Chih-Chien Hsu; Tai-Chi Lin; Shih-Jen Chen; De-Kuang Hwang
TAGS: biological markers, polygenic risk score, retinal detachment, screening, ultrasonography, hypertension
Trans. Vis. Sci. Tech.. 2025; 14(4):16. https://doi.org/10.1167/tvst.14.4.16

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Comparable efficacy with aflibercept 8 mg at extended dosing intervals beyond q16 versus 2 mg q8 in Asian patients with nAMD in PULSAR through Week 96

Xiaodong Sun; Shih-Jen Chen; xin Zhang; Andrea Schulze; Tobias Machewitz; Min Zhao; Sergio Leal

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):220.

Cornea & External Disease May 2024

Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model

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Chih-Chien Hsu; Hao-Kai Chuang; Yu-Jer Hsiao; Pin-Hsuan Chiang; Szu-Wen Chen; Wei-Ting Luo; Yi-Ping Yang; Ping-Hsing Tsai; Shih-Jen Chen; Ai-Ru Hsieh; Shih-Hwa Chiou
TAGS: dry eye syndromes, genome, genome-wide association study, polygenic risk score
Trans. Vis. Sci. Tech.. 2024; 13(5):13. https://doi.org/10.1167/tvst.13.5.13

Includes: Supplemental Content

Genetics September 2023

TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis

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Hao-Kai Chuang; Ai-Ru Hsieh; Tien-Yap Ang; Szu-Wen Chen; Yi-Ping Yang; Hung-Juei Huang; Shih-Hwa Chiou; Tai-Chi Lin; Shih-Jen Chen; Chih-Chien Hsu; De-Kuang Hwang
TAGS: genetic risk, genome-wide association study, polygenic risk score, polymorphism, retinal detachment, vipr2 gene
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):17. https://doi.org/10.1167/iovs.64.12.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Durable vision gains and greater fluid control with extended faricimab dosing vs aflibercept in patients with DME

Jennifer I Lim; Shih-Jen Chen; Nathan Steinle; Glenn J Jaffe; Bianca S Gerendas; Francis Abreu; Acner Camino; Kara Gibson; Nitin Jain; Eugene Shildkrot; Audrey Souverain; Yannan Tang; Jeffrey Willis; Zdenka Haskova

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2815.

ARVO Annual Meeting Abstract June 2022

Predicting Visual Outcome in Patients with Idiopathic Epiretinal Membrane Using A Novel Convolutional Neural Network

Tsai-Chu Yeh; Yu-Chieh Ko; Yu-Bai Chou; Shih-Jen Chen; An-Chun Luo; Yu-Shan Deng

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2083 – F0072.

ARVO Annual Meeting Abstract June 2022

Deep learning assisted prediction of long-term visual outcome after 3 monthly anti-vascular endothelial growth factor injections in patients with central-involved diabetic macular edema

Yu-Chieh Ko; Chih-Wei Peng; Hshin-Chi Ho; Shih-Hwa Chiu; Shih Jen Chen; Chen-Yi Lee

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3778 – F0199.

Articles February 2022

Diagnosis of Polypoidal Choroidal Vasculopathy From Fluorescein Angiography Using Deep Learning

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Yu-Yeh Tsai; Wei-Yang Lin; Shih-Jen Chen; Paisan Ruamviboonsuk; Cheng-Ho King; Chia-Ling Tsai
TAGS: attention, choroidal neovascularization, deep learning, fluorescein angiography, polypoidal choroidal vasculopathy, datasets
Trans. Vis. Sci. Tech.. 2022; 11(2):6. https://doi.org/10.1167/tvst.11.2.6

ARVO Annual Meeting Abstract June 2020

Parafoveal atrophy after human amniotic membrane graft for macular hole in patients with high myopia

Der-Chong Tsai; Yu-Hsuan Huang; Shih Jen Chen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4242.

ARVO Annual Meeting Abstract June 2020

Artificial Intelligence Machine Learning of Optical Coherence Tomography Angiography for the Diagnosis of Age-related Macular degeneration

TAI-CHI LIN; Ying-Chun Jheng; Shih-Jen Chen; Shih-Hwa Chiou

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2031.

ARVO Annual Meeting Abstract July 2019

Treat-and-extend regimen with aflibercept in treating diabetic macular edema: the JADE study

Shih Jen Chen; Shwu-Jiuan Sheu; Chang-Hao Yang; Chi-Chun Lai; Pei-Chang Wu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2609.

ARVO Annual Meeting Abstract July 2019

Combination therapy with oral mineralocorticoid antagonist and ophthalmic glucocorticoid for non-resolving central serous chorioretinopathy.

Der-Chong Tsai; De-Kuang Hwang; Shih Jen Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5039.

ARVO Annual Meeting Abstract July 2018

Factors Associated with Acute Worsening of Retinopathy in Diabetic Patients after Pancreas Transplantation in Chinese

Fang-Yi Tsai; Ling-Ing Lau; An-Fei Li; Shih-Jen Chen; Catherine Jui-Ling Liu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1896.

ARVO Annual Meeting Abstract July 2018

2-Year Results of the PLANET Study: Intravitreal Aflibercept Alone and With Rescue Photodynamic Therapy in Polypoidal Choroidal Vasculopathy

Won Ki Lee; Yuichiro Ogura; Tomohiro Iida; Shih-Jen Chen; Tien Yin Wong; Paul Mitchell; Jeannie Qiu; Sergio Leal; Tatsuro Ishibashi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4949.

ARVO Annual Meeting Abstract June 2017

Efficacy and Safety of Intravitreal Aflibercept in Polypoidal Choroidal Vasculopathy: 12-Month Results of the PLANET Study

Won Ki Lee; Yuichiro Ogura; Tomohiro Iida; Shih-Jen Chen; Tien Yin Wong; Paul Mitchell; Tatsuro Ishibashi; eric zhang; Sergio Leal

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1199.

Genetics July 2016

Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa

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Nana Hsiang-Hua Wang; Shih-Jen Chen; Chi-Fan Yang; Hui-Wen Chen; Hui-Ping Chuang; Yung-Hsiu Lu; Chien-Hsiun Chen; Jer-Yuarn Wu; Dau-Ming Niu; Yuan-Tsong Chen
TAGS: autosomal recessive inheritance, genome, homozygote, missense mutation, mutation, retinitis pigmentosa, family
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3601-3609. https://doi.org/10.1167/iovs.16-19463

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Localization of Polypoidal Choroidal Vasculopathy in Fluorescein Angiography using Semi-Supervised Deep Learning

Faricimab for Polypoidal Choroidal Vasculopathy: Week 16 Results From the Phase 3b/4 SALWEEN Trial

Instrumenting Anatomy-sensible Models to Predict Individual Visual Acuity Loss From Layer-wise OCT-Angiography Vascular Morphology

Leveraging LLM Technology: Development of an AI-Powered Agent for Cataract Surgery Education and IOL Selection

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

Comparable efficacy with aflibercept 8 mg at extended dosing intervals beyond q16 versus 2 mg q8 in Asian patients with nAMD in PULSAR through Week 96

Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model

TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis

Durable vision gains and greater fluid control with extended faricimab dosing vs aflibercept in patients with DME

Predicting Visual Outcome in Patients with Idiopathic Epiretinal Membrane Using A Novel Convolutional Neural Network

Deep learning assisted prediction of long-term visual outcome after 3 monthly anti-vascular endothelial growth factor injections in patients with central-involved diabetic macular edema

Diagnosis of Polypoidal Choroidal Vasculopathy From Fluorescein Angiography Using Deep Learning

Parafoveal atrophy after human amniotic membrane graft for macular hole in patients with high myopia

Artificial Intelligence Machine Learning of Optical Coherence Tomography Angiography for the Diagnosis of Age-related Macular degeneration

Treat-and-extend regimen with aflibercept in treating diabetic macular edema: the JADE study

Combination therapy with oral mineralocorticoid antagonist and ophthalmic glucocorticoid for non-resolving central serous chorioretinopathy.

Factors Associated with Acute Worsening of Retinopathy in Diabetic Patients after Pancreas Transplantation in Chinese

2-Year Results of the PLANET Study: Intravitreal Aflibercept Alone and With Rescue Photodynamic Therapy in Polypoidal Choroidal Vasculopathy

Efficacy and Safety of Intravitreal Aflibercept in Polypoidal Choroidal Vasculopathy: 12-Month Results of the PLANET Study

Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa

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