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ARVO Annual Meeting Abstract June 2024

Cone contributions to the ERG of the RPE65 -/- dog

Geneive M Carrion; Paige A Winkler; Kelian Sun; Laurence Occelli; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4740.

ARVO Annual Meeting Abstract June 2024

AAV2 gene therapy rescues rod photoreceptor functional recovery in the RDH5 -mutant cat

Laura Ford; Laurence Occelli; Kelian Sun; Mary Enfield; William Hauswirth; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6080.

Retina June 2023

Cat LCA- CRX Model, Homozygous for an Antimorphic Mutation Has a Unique Phenotype

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Laurence M. Occelli; Nicholas M. Tran; Shiming Chen; Simon M. Petersen-Jones
TAGS: cats, eye, homozygote, mutation, phenotype, photoreceptors, retina, spectral domain-optical coherence tomography, transcription factor, tissue degeneration
Trans. Vis. Sci. Tech.. 2023; 12(6):15. https://doi.org/10.1167/tvst.12.6.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Maturation of synaptic ribbons and synaptogenesis occur after CaBP4 gene augmentation therapy

Billie Beckwith-Cohen; Paige A Winkler; Kelian Sun; Laurence M Occelli; Luis Felipe Marinho; Fabiano Montiani-Ferreira; William W Hauswirth; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1915.

ARVO Annual Meeting Abstract June 2021

A disease-modifying therapy for retinal degenerations by drug repurposing

Henri Olavi Leinonen; Jianye Zhang; Fangyuan Gao; Elliot H Choi; Elliott E Einstein; David E Einstein; Laurence Mireille Occelli; Luis Felipe Marinho; Alexander V Kolesnikov; Vladimir Kefalov; Dorota Skowronska-Krawczyk; Seth Blackshaw; Simon M Petersen-Jones; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3157.

ARVO Annual Meeting Abstract June 2020

Testing of a therapeutic vector for CNGB1 retinitis pigmentosa

Simon M Petersen-Jones; Laurence Mireille Occelli; Johanna Wagner; Luis Marinho; Amy Frederick; Catherine O'Riordan; Stylianos Michalakis

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):793.

ARVO Annual Meeting Abstract June 2020

Gene augmentation therapy in a large animal model of PDE6A -Retinitis Pigmentosa results in functional and structural rescue for at least 2.5 years.

Laurence Mireille Occelli; Stylianos Michalakis; Martin Biel; consortium RD-Cure; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1913.

ARVO Annual Meeting Abstract June 2020

Light and Dark discrimination testing in Gnb3 -/- rats

Marianna Bacellar-Galdino; John Rozofsky; Simon M Petersen-Jones; Jeffrey Adam Jamison

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4280.

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. https://doi.org/10.1167/tvst.9.7.2

ARVO Annual Meeting Abstract July 2019

New large animal model for RDH5 -associated retinopathies

Simon M Petersen-Jones; Laurence Occelli; Paige Winkler; Andrea Minella; Kelian Sun; Leslie Lyons; Anahita Daruwalla; Philip Kiser; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):458.

ARVO Annual Meeting Abstract July 2019

Autosomal recessive night blindness with progressive photoreceptor degeneration in a dog model

Luis Lima Pompeo Marinho; Laurence Mireille Occelli; Nate Pasmanter; Andre Tavares Somma; Fabiano Montiani-Ferreira; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):465.

ARVO Annual Meeting Abstract July 2018

Transplantation of laboratory-grown human retinal tissue in the subretinal space of the cat eye

Ratnesh K Singh; Laurence Occelli; Simon M Petersen-Jones; Francois Binette; Oscar Cuzzani; Igor O Nasonkin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2986.

Retina June 2017

Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs

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Freya M. Mowat; Kristen J. Gervais; Laurence M. Occelli; Matthew J. Annear; Janice Querubin; James W. Bainbridge; Alexander J. Smith; Robin R. Ali; Simon M. Petersen-Jones
TAGS: dog, domestic, retina, retinal cone, tissue degeneration, photoreceptors, rod photoreceptors, opsin, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3268-3277. https://doi.org/10.1167/iovs.17-21930

ARVO Annual Meeting Abstract June 2017

Gene augmentation therapy improves inner and outer segment morphology and preserves retinal structure in a large animal model of CNGB1 -retinitis pigmentosa

Laurence Mireille Occelli; Paige A Winkler; Vince A Chiodo; Sanford L Boye; William W Hauswirth; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4508.

Visual Neuroscience January 2017

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response

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Connie Y. Yeh; Kristin L. Koehl; Christine D. Harman; Simone Iwabe; José M. Guzman; Simon M. Petersen-Jones; Randy H. Kardon; András M. Komáromy
TAGS: dog, domestic, pupil reaction, retinal cone, rod photoreceptors, pupillometry, melanopsin, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):65-78. https://doi.org/10.1167/iovs.16-19865

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Gene augmentation therapy in a large animal model of CNGB1 retinitis pigmentosa

Simon M Petersen-Jones; Laurence Mireille Occelli; Paige Winkler; Vince Chiodo Chiodo; Sanford L. Boye; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Metabolic changes during late stage retinal degeneration in heterozygous Crx mutant cats ( Crx Rdy/+ ).

Laurence Mireille Occelli; Bryan W Jones; Simon M Petersen-Jones

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2260.

Retinal Cell Biology July 2016

Crx Rdy Cat: A Large Animal Model for CRX -Associated Leber Congenital Amaurosis

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Laurence M. Occelli; Nicholas M. Tran; Kristina Narfström; Shiming Chen; Simon M. Petersen-Jones
TAGS: adaptive testing, animal model, cats, electroretinography, leber's amaurosis, photoreceptors, retina, retinal cone, rod photoreceptors, proteins
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3780-3792. https://doi.org/10.1167/iovs.16-19444

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Dose-response effect of RPE65 gene therapy on retinoid levels and correlation with clinical rescue in Rpe65-deficient dogs.

Freya Mowat; Kecia L Feathers; Alexander J Smith; Debra A Thompson; Simon M Petersen-Jones; James W B Bainbridge; Robin R Ali

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2064.

ARVO Annual Meeting Abstract June 2015

Assessment of rod, cone, and intrinsically photosensitive retinal ganglion cell (ipRGC) contribution to the canine chromatic pupillary response

Connie Yeh; Kristin L Koehl; Christine Harman; Simone Iwabe; Jose Guzman; Simon M Petersen-Jones; Andras M Komaromy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5569.

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Cone contributions to the ERG of the RPE65 -/- dog

AAV2 gene therapy rescues rod photoreceptor functional recovery in the RDH5 -mutant cat

Cat LCA- CRX Model, Homozygous for an Antimorphic Mutation Has a Unique Phenotype

Maturation of synaptic ribbons and synaptogenesis occur after CaBP4 gene augmentation therapy

A disease-modifying therapy for retinal degenerations by drug repurposing

Testing of a therapeutic vector for CNGB1 retinitis pigmentosa

Gene augmentation therapy in a large animal model of PDE6A -Retinitis Pigmentosa results in functional and structural rescue for at least 2.5 years.

Light and Dark discrimination testing in Gnb3 -/- rats

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

New large animal model for RDH5 -associated retinopathies

Autosomal recessive night blindness with progressive photoreceptor degeneration in a dog model

Transplantation of laboratory-grown human retinal tissue in the subretinal space of the cat eye

Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs

Gene augmentation therapy improves inner and outer segment morphology and preserves retinal structure in a large animal model of CNGB1 -retinitis pigmentosa

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response

Gene augmentation therapy in a large animal model of CNGB1 retinitis pigmentosa

Metabolic changes during late stage retinal degeneration in heterozygous Crx mutant cats ( Crx Rdy/+ ).

Crx Rdy Cat: A Large Animal Model for CRX -Associated Leber Congenital Amaurosis

Dose-response effect of RPE65 gene therapy on retinoid levels and correlation with clinical rescue in Rpe65-deficient dogs.

Assessment of rod, cone, and intrinsically photosensitive retinal ganglion cell (ipRGC) contribution to the canine chromatic pupillary response

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