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ARVO Annual Meeting Abstract June 2025

Specializing vision-language models for the clinical management of age-related macular degeneration

Martin Menten; Robbie Holland; Tom Taylor; Christopher Holmes; Sophie Riedl; Julia Mai; Maria Patsiamanidi; Dimitra Mitsopoulou; Paul Hager; Philip Müller; Johannes Paetzold; Hendrik P Scholl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Daniel Rückert; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):863.

ARVO Annual Meeting Abstract June 2025

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Marie Louise Enzendorfer; Julia Mai; Sophie Riedl; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1334.

ARVO Annual Meeting Abstract June 2025

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Arunava Chakravarty; Julia Mai; Taha Emre; Marie Louise Enzendorfer; Sophie Riedl; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Toby Prevost; Martin Menten; Daniel Rueckert; Andrew J Lotery; Hrvoje Bogunovic; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4086.

ARVO Annual Meeting Abstract June 2025

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Sophie Frank; Klaudia Birner; Julia Mai; Sophie Riedl; Magdalena Baratsits; Simon Schürer-Waldheim; Markus Gumpinger; Hrvoje Bogunovic; Manjula Nugawela; Martin Menten; Daniel Rueckert; Lars G Fritsche; Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1340.

ARVO Annual Meeting Abstract June 2025

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Julia Mai; Sophie Riedl; Louise Enzendorfer; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1075.

Retina February 2025

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

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Stefan Futterknecht; Philipp Anders; Julia Mai; Sophie Riedl; Ursula Hall; Chrysoula Gabrani; Kristina Pfau; Martin J. Menten; Daniel Rueckert; A. Toby Prevost; Hrvoje Bogunovic; Lars G. Fritsche; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P. N. Scholl; Maximilian Pfau
TAGS: drusen, study report, vision, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):6. https://doi.org/10.1167/iovs.66.2.6

Includes: Supplemental Content

Retina July 2024

Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning

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Sophie Riedl; Ursula Schmidt-Erfurth; Antoine Rivail; Klaudia Birner; Julia Mai; Wolf-Dieter Vogl; Zhichao Wu; Robyn H. Guymer; Hrvoje Bogunović; Gregor S. Reiter
TAGS: atrophy, cohort studies, deep learning, drusen, diagnostic imaging, eye, atrophic condition of skin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):30. https://doi.org/10.1167/iovs.65.8.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Sophie Riedl; Julia Mai; Simon Schürer-Waldheim; Georg Faustmann; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):980.

ARVO Annual Meeting Abstract June 2024

Variability of perilesional FAF patterns associated with automated OCT-based PR/RPE loss ratios in GA progression in the phase 3 OAKS/DERBY trials

Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Wolf-Dieter Vogl; Amir Sadeghipour; Alex McKeown; Hrvoje Bogunovic; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):981.

ARVO Annual Meeting Abstract June 2024

Enriching AI-based Predictive Models from Retinal Imaging by Multi-Modal Contrastive Pre-training

Emese Sükei; Sophie Riedl; Elisabeth Rumetshofer; Niklas Schmidinger; Andreas Mayr; Ursula Schmidt-Erfurth; Günter Klambauer; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):450.

ARVO Annual Meeting Abstract June 2024

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Christopher Holmes; Naomi Wijesingha; Syed Ahmer Raza; Tom Taylor; Ahmed Hagag; Sophie Riedl; Julia Mai; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars Fritsche; Andrew Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3264.

ARVO Annual Meeting Abstract June 2024

Predictive value of the photoreceptor/RPE loss ratio on OCT in the management of geographic atrophy (GA) for patient selection and monitoring of therapeutic efficacy

Ursula Schmidt-Erfurth; Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Wolf-Dieter Vogl; Amir Sadeghipour; Alex McKeown; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3263.

Artificial Intelligence June 2024

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

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Guilherme Aresta; Teresa Araujo; Gregor S. Reiter; Julia Mai; Sophie Riedl; Christoph Grechenig; Robyn H. Guymer; Zhichao Wu; Ursula Schmidt-Erfurth; Hrvoje Bogunovic
TAGS: biological markers, datasets, lead, volume, eye, deep learning
Trans. Vis. Sci. Tech.. 2024; 13(6):7. https://doi.org/10.1167/tvst.13.6.7

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

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Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Robbie Holland; Oliver Leingang; Ahmed M Hagag; Christopher Holmes; Philipp Anders; Johannes C. C. Paetzold; Rebecca Kaye; Sophie Riedl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Hendrik P Scholl; Daniel Rueckert; Andrew J Lotery; Sobha Sivaprasad; Martin Joseph Menten

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1283.

ARVO Annual Meeting Abstract June 2023

Automated INL/OPL subsidence detection in intermediate AMD with deep neural networks

Guilherme Aresta; Teresa Araújo; Sophie Riedl; Gregor Sebastian Reiter; Robyn H Guymer; Zhichao Wu; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1284.

ARVO Annual Meeting Abstract June 2023

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Philipp Anders; Ghislaine L Traber; Maximilian Pfau; Sophie Riedl; Julia Mai; Hanna Camenzind; Chrysoula Gabrani; Rebecca Kaye; Toby Prevost; Hrvoje Bogunovic; Lars G Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4328.

ARVO Annual Meeting Abstract June 2023

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Arunava Chakravarty; Taha Emre; Oliver Leingang; Sophie Riedl; Julia Mai; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Daniel Rueckert; Andrew J Lotery; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):545.

ARVO Annual Meeting Abstract June 2023

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Christopher Holmes; Syed Ahmer Raza; Ahmed M Hagag; Thomas Taylor; Sophie Riedl; Julia Mai; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars G Fritsche; Andrew J Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2171.

ARVO Annual Meeting Abstract June 2022

Adaptive optics phenotypes of intermediate age-related macular degeneration

Ahmed M Hagag; Sophie Riedl; Toby Prevost; Lars Fritsche; Daniel Rueckert; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2322.

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Specializing vision-language models for the clinical management of age-related macular degeneration

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Variability of perilesional FAF patterns associated with automated OCT-based PR/RPE loss ratios in GA progression in the phase 3 OAKS/DERBY trials

Enriching AI-based Predictive Models from Retinal Imaging by Multi-Modal Contrastive Pre-training

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Predictive value of the photoreceptor/RPE loss ratio on OCT in the management of geographic atrophy (GA) for patient selection and monitoring of therapeutic efficacy

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Automated INL/OPL subsidence detection in intermediate AMD with deep neural networks

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Adaptive optics phenotypes of intermediate age-related macular degeneration

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