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Journal Articles (8)
Meeting Abstract (6)

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Investigative Ophthalmology & Visual Science (13)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (6)
Cornea (6)
Articles (1)
Multidisciplinary Ophthalmic Imaging (1)

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Cornea (8)
Eye Anatomy and Disorders (8)
Pharmacology (2)
Surgery (2)
Genetics (1)
Multidisciplinary Ophthalmic Imaging (1)
Translational Research (1)
Visual Psychophysics and Physiological Optics (1)

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cross-linking (7)
corneal collagen cross-linking (6)
body tissue (4)
cornea (4)
body temperature (3)
temperature (3)
heat shrinkage procedure (2)
oryctolagus cuniculus (2)
riboflavin (2)
sclera (2)

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Articles August 2020

Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits

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Mariya Zyablitskaya; Charles Jayyosi; Anna Takaoka; Kristin M. Myers; Leejee H. Suh; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: cornea, corneal collagen cross-linking, cross-linking, oryctolagus cuniculus, dutch, optical pachymetry, epithelium, intraocular pressure
Trans. Vis. Sci. Tech.. 2020; 9(9):20. https://doi.org/10.1167/tvst.9.9.20

ARVO Annual Meeting Abstract July 2019

Evaluation of a topical corneal cross-linking solution using sodium hydroxymethylglycinate by intravital confocal microscopy in the Dutch-belted rabbit: a follow up report on keratocyte morphologic changes.

David C Paik; Mariya Zyablitskaya; Anna Takaoka; Jaya R. Mehta; Estee Hong; Sara Fallahi; Leejee Suh; Takayuki Nagasaki; Stephen L. Trokel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):354.

Cornea January 2018

Antimicrobial Studies Using the Therapeutic Tissue Cross-Linking Agent, Sodium Hydroxymethylglycinate: Implication for Treating Infectious Keratitis

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Patrick B. Rapuano; Alexandra H. Scanameo; Daeryl E. Amponin; Sefy A. Paulose; Mariya Zyablitskaya; Anna Takaoka; Leejee H. Suh; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: antimicrobials, body tissue, cross-linking, keratitis, sodium, methicillin-resistant staphylococcus aureus
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):332-337. https://doi.org/10.1167/iovs.17-23111

Multidisciplinary Ophthalmic Imaging August 2017

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia Using Second Harmonic Generation Signal Microscopy in Rabbit Sclera

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Mariya Zyablitskaya; Anna Takaoka; Emilia L. Munteanu; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: body tissue, harmonics, myopia, oryctolagus cuniculus, sclera, eye, riboflavin, injections, corneal collagen cross-linking
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):21-29. https://doi.org/10.1167/iovs.16-20241

Cornea January 2016

An Evaluation of Lysyl Oxidase–Derived Cross-Linking in Keratoconus by Liquid Chromatography/Mass Spectrometry

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Anna Takaoka; Natasha Babar; Julia Hogan; MiJung Kim; Marianne O. Price; Francis W. Price, Jr; Stephen L. Trokel; David C. Paik
TAGS: body temperature, body tissue, collagen, cornea, cross-linking, keratoconus, liquid chromatography, mass spectrometry, protein-lysine 6-oxidase, fibril
Invest. Ophthalmol. Vis. Sci.. 2016; 57(1):126-136. https://doi.org/10.1167/iovs.15-18105

Cornea February 2015

Cosmetic Preservatives as Therapeutic Corneal and Scleral Tissue Cross-Linking Agents

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Natasha Babar; MiJung Kim; Kerry Cao; Yukari Shimizu; Su-Young Kim; Anna Takaoka; Stephen L. Trokel; David C. Paik
TAGS: body tissue, cornea, cross-linking, sclera, corneal collagen cross-linking
Invest. Ophthalmol. Vis. Sci.. 2015; 56(2):1274-1282. https://doi.org/10.1167/iovs.14-16035

Cornea May 2014

Pharmacologic Alternatives to Riboflavin Photochemical Corneal Cross-Linking: A Comparison Study of Cell Toxicity Thresholds

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MiJung Kim; Anna Takaoka; Quan V. Hoang; Stephen L. Trokel; David C. Paik
TAGS: corneal collagen cross-linking, cross-linking, riboflavin, toxic effect, pharmacology, comparative study research
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3247-3257. https://doi.org/10.1167/iovs.13-13703

ARVO Annual Meeting Abstract April 2014

Quantification of corneal density changes following corneal collagen crosslinking and its relationship to clinical outcomes

Brad E Kligman; Leejee Han Suh; Francis W Price; Marianne O Price; Stephen L Trokel

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1551.

ARVO Annual Meeting Abstract April 2014

Native enzymatic collagen cross-linking in human cornea as determined by simultaneous fluorescence and mass spectometry (LC/MS)

David C Paik; Anna Takaoka; Stephen L Trokel

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4210.

ARVO Annual Meeting Abstract April 2014

Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking (XL) agents

Natasha Babar; Jessica R Cohen; Michael J Fernandez; Anna Takaoka; Xia Li; Mi Jung Kim; Kristin M Myers; Stephen L Trokel; David C Paik

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4214.

ARVO Annual Meeting Abstract April 2014

An evaluation of enzymatic collagen cross-linking in keratoconus using LC/MS

Anna Takaoka; Julia Hogan; Natasha Babar; Mi Jung Kim; Marianne O Price; Francis W Price; Stephen L Trokel; David C Paik

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4221.

ARVO Annual Meeting Abstract March 2012

Aliphatic β-nitroalcohols For Therapeutic Corneoscleral Cross-linking: Chemical Stability Studies Using 1H-NMR

David C. Paik; Xia Li; Yongjun Li; Stephen L. Trokel; Nicholas J. Turro

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1514.

Cornea February 2010

Aliphatic β-Nitroalcohols for Therapeutic Corneoscleral Cross-linking: Chemical Mechanisms and Higher Order Nitroalcohols

PDF

David C. Paik; Marissa R. Solomon; Quan Wen; Nicholas J. Turro; Stephen L. Trokel
TAGS: body temperature, cross-linking, formaldehyde, nitrites, temperature, heat shrinkage procedure
Invest. Ophthalmol. Vis. Sci.. 2010; 51(2):836-843. https://doi.org/10.1167/iovs.09-3937

Cornea March 2009

Initial Studies Using Aliphatic β-Nitro Alcohols for Therapeutic Corneal Cross-Linking

PDF

David C. Paik; Quan Wen; Richard E. Braunstein; Suzanna Airiani; Stephen L. Trokel
TAGS: alcohols, cornea, corneal collagen cross-linking, cross-linking, temperature, heat shrinkage procedure, body temperature
Invest. Ophthalmol. Vis. Sci.. 2009; 50(3):1098-1105. https://doi.org/10.1167/iovs.08-2202

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