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Lens July 2024

Connexin 50 Influences the Physiological Optics of the In Vivo Mouse Lens

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Xingzheng Pan; Eric R. Muir; Caterina Sellitto; Zhao Jiang; Paul J. Donaldson; Thomas W. White
TAGS: lens (device), lens, crystalline, mice, optics, gap junction protein, water, physiological optics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):19. https://doi.org/10.1167/iovs.65.8.19

ARVO Annual Meeting Abstract June 2024

Presbyopia treatment with 1.25% pilocarpine alters free water distribution in the human lens

Alyssa L Lie; Xingzheng Pan; Oscar Lee; Regina Lee; Thomas William White; Paul J Donaldson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6315.

Lens October 2023

Single-Cell RNA Sequencing Analysis of the Early Postnatal Mouse Lens Epithelium

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Adrienne A. Giannone; Caterina Sellitto; Barbara Rosati; David McKinnon; Thomas W. White
TAGS: genes, lens (device), lens epithelium, lens, crystalline, mice, rna, small cytoplasmic, sequence analysis, rna, signal transduction, gene expression
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):37. https://doi.org/10.1167/iovs.64.13.37

Includes: Supplemental Content

Lens April 2023

Age-Dependent Changes in the Water Content and Optical Power of the In Vivo Mouse Lens Revealed by Multi-Parametric MRI and Optical Modeling

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Xingzheng Pan; Eric R. Muir; Caterina Sellitto; Kehao Wang; Catherine Cheng; Barbara Pierscionek; Paul J. Donaldson; Thomas W. White
TAGS: lens (device), lens, crystalline, mice, optics, water, biological transport, aging, shape
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):24. https://doi.org/10.1167/iovs.64.4.24

Lens July 2021

Age-Dependent Changes in Total and Free Water Content of In Vivo Human Lenses Measured by Magnetic Resonance Imaging

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Alyssa L. Lie; Xingzheng Pan; Thomas W. White; Ehsan Vaghefi; Paul J. Donaldson
TAGS: lens, crystalline, magnetic resonance imaging, water, lens (device), aging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):33. https://doi.org/10.1167/iovs.62.9.33

ARVO Annual Meeting Abstract June 2021

Age-dependent changes to the free and total water distribution of the in vivo human lens measured by MRI

Alyssa Lesley Lie; Xingzheng Pan; Thomas William White; Paul J Donaldson; Ehsan Vaghefi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2095.

Articles July 2020

Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens

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Alyssa L. Lie; Xingzheng Pan; Thomas W. White; Paul J. Donaldson; Ehsan Vaghefi
TAGS: lens (device), lens, crystalline, magnetic resonance imaging, refractive errors, optics, aging, calibration
Trans. Vis. Sci. Tech.. 2020; 9(8):39. https://doi.org/10.1167/tvst.9.8.39

Lens June 2020

Signaling Between TRPV1/TRPV4 and Intracellular Hydrostatic Pressure in the Mouse Lens

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Nicholas A. Delamere; Mohammad Shahidullah; Richard T. Mathias; Junyuan Gao; Xiuron Sun; Caterina Sellitto; Thomas W. White
TAGS: gap junction protein, hydrostatic pressure, lens (device), lens, crystalline, trpv1 receptor, mice, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):58. https://doi.org/10.1167/iovs.61.6.58

Lens October 2019

The Ciliary Muscle and Zonules of Zinn Modulate Lens Intracellular Hydrostatic Pressure Through Transient Receptor Potential Vanilloid Channels

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Yadi Chen; Junyuan Gao; Leping Li; Caterina Sellitto; Richard T. Mathias; Paul J. Donaldson; Thomas W. White
TAGS: ciliary muscle, hydrostatic pressure, lens (device), lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4416-4424. https://doi.org/10.1167/iovs.19-27794

Lens September 2019

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

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Sumin Gu; Sondip Biswas; Luis Rodriguez; Zhen Li; Yuting Li; Manuel A. Riquelme; Wen Shi; Ke Wang; Thomas W. White; Matthew Reilly; Woo-Kuen Lo; Jean X. Jiang
TAGS: lens (device), lens, crystalline, gap junction protein, mice, personal integrity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4021-4032. https://doi.org/10.1167/iovs.18-26270

Lens September 2019

Lens Connexin Channels Have Differential Permeability to the Second Messenger cAMP

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Virginijus Valiunas; Peter R. Brink; Thomas W. White
TAGS: cyclic amp, gap junction protein, lens (device), permeability, lens, crystalline, connexin 43, second messenger systems
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3821-3829. https://doi.org/10.1167/iovs.19-27302

ARVO Annual Meeting Abstract July 2018

The lens paradox is due to an age-related shift in optical centre of the lens

Alyssa Lesley Lie; Xingzheng Pan; Paul J Donaldson; Thomas William White; Ehsan Vaghefi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4698.

ARVO Annual Meeting Abstract September 2016

Differences in second messenger permeability of lens connexins

Thomas William White

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

Lens June 2016

The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth

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Caterina Sellitto; Leping Li; Ehsan Vaghefi; Paul J. Donaldson; Richard Z. Lin; Thomas W. White
TAGS: catalytic domain, lens (device), lens, crystalline, phosphotransferases, mice
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3145-3151. https://doi.org/10.1167/iovs.16-19607

ARVO Annual Meeting Abstract June 2015

Connexin 50 Functions as an Adhesive Molecule and Promotes the Cell-Cell Adhesion Function of Aquaporin 0 in the Lens

zhengping Hu; Sumin Gu; Sondip K Biswas; Alan Shiels; Thomas William White; Woo-Kuen Lo; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2644.

Lens November 2013

The Effects of Age on Lens Transport

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Junyuan Gao; Huan Wang; Xiurong Sun; Kulandaiappan Varadaraj; Leping Li; Thomas W. White; Richard T. Mathias
TAGS: lens (device), lens, crystalline, gap junction protein
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7174-7187. https://doi.org/10.1167/iovs.13-12593

ARVO Annual Meeting Abstract June 2013

Gap junctional conductance produced by Cx50, but not Cx46, is regulated by the PI3K signaling pathway in the lens

Jennifer Martinez; Hong Zhan Wang; Pallavi Mhaske; Caterina Sellitto; Miduturu Srinivas; Richard Lin; Thomas White

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5750.

Lens January 2013

The Effect of Size and Species on Lens Intracellular Hydrostatic Pressure

PDF

Junyuan Gao; Xiurong Sun; Leon C. Moore; Peter R. Brink; Thomas W. White; Richard T. Mathias
TAGS: lens (device), lens, crystalline, hydrostatic pressure, mice
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):183-192. https://doi.org/10.1167/iovs.12-10217

ARVO Annual Meeting Abstract April 2011

The Effect of Lens Size on the Circulation of Salt and Water through the Lens

Richard T. Mathias; Leon C. Moore; Thomas W. White; Peter R. Brink; Xiurong Sun; Junyuan Gao

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3415.

ARVO Annual Meeting Abstract April 2011

Interactions Between Gap Junctional Communication And Phosphoinositide 3-kinase Signaling In Lens Growth

Thomas W. White; Caterina Sellitto; Leping Li; Hong-Zhan Wang; Michael L. Robinson; Miduturu Srinivas; Richard Z. Lin

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3928.

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Connexin 50 Influences the Physiological Optics of the In Vivo Mouse Lens

Presbyopia treatment with 1.25% pilocarpine alters free water distribution in the human lens

Single-Cell RNA Sequencing Analysis of the Early Postnatal Mouse Lens Epithelium

Age-Dependent Changes in the Water Content and Optical Power of the In Vivo Mouse Lens Revealed by Multi-Parametric MRI and Optical Modeling

Age-Dependent Changes in Total and Free Water Content of In Vivo Human Lenses Measured by Magnetic Resonance Imaging

Age-dependent changes to the free and total water distribution of the in vivo human lens measured by MRI

Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens

Signaling Between TRPV1/TRPV4 and Intracellular Hydrostatic Pressure in the Mouse Lens

The Ciliary Muscle and Zonules of Zinn Modulate Lens Intracellular Hydrostatic Pressure Through Transient Receptor Potential Vanilloid Channels

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Lens Connexin Channels Have Differential Permeability to the Second Messenger cAMP

The lens paradox is due to an age-related shift in optical centre of the lens

Differences in second messenger permeability of lens connexins

The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth

Connexin 50 Functions as an Adhesive Molecule and Promotes the Cell-Cell Adhesion Function of Aquaporin 0 in the Lens

The Effects of Age on Lens Transport

Gap junctional conductance produced by Cx50, but not Cx46, is regulated by the PI3K signaling pathway in the lens

The Effect of Size and Species on Lens Intracellular Hydrostatic Pressure

The Effect of Lens Size on the Circulation of Salt and Water through the Lens

Interactions Between Gap Junctional Communication And Phosphoinositide 3-kinase Signaling In Lens Growth

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