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ARVO Annual Meeting Abstract June 2024

Surgical approach for the implantation of a capsular ring electrode into the posterior chamber

Friederike Charlotte Kortuem; Sebastian Kaltenstadler; Sven Schumayer; Bishesh Sigdel; Immanuel Philipp Seitz; Tobias Peters; Albrecht Rothermel; Volker Bucher; Eberhart Zrenner; Karl-Ulrich Bartz-Schmidt; Torsten Strasser

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2086.

ARVO Annual Meeting Abstract June 2024

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Tobias Peters; Katarina Stingl; Wolfgang Klein; Mario G Fsadni; Nils Meland; Patty P.A. Dhooge; Camiel Boon; Andrew Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Frank G Holz; Steffen Schmitz-Valckenberg; Philipp Möller; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2205.

ARVO Annual Meeting Abstract June 2024

Host cell protein impurities are not a relevant driver of gene therapy-associated immune response

Immanuel Philipp Seitz; Eduardo Bocanegra; Felix Reichel; Stylianos Michalakis; Martin Biel; Karl Ulrich Bartz-Schmidt; Tobias Peters; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5345.

ARVO Annual Meeting Abstract June 2024

A new subretinal gene therapy for USH1C is well tolerated in wild type pigs

Peter Kiraly; Matthias Mai; Tobias Peters; Immanuel P Seitz; Taras Ardan; Zdenka Ellederova; Yaroslav Nemesh; Ruslan Nyshchuk; Nikolai Klymiuk; Ashley Winslow; Joshua Klein; Kerstin Nagel-Wolfrum; Uwe Wolfrum; Jan Motlik; M Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5341.

Retina June 2024

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

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Ricarda Jendritza; Krunoslav Stingl; Torsten Strasser; Ronja Jung; Felix Tonagel; Paul Richter; Anton Sonntag; Tobias Peters; Helmut Wilhelm; Barbara Wilhelm; Carina Kelbsch
TAGS: biological markers, cardiac progenitor cells, cohort studies, pupil, pupil light reflex, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):3. https://doi.org/10.1167/iovs.65.6.3

Retina August 2023

Rod and Cone Function Measured Objectively by Chromatic Pupil Campimetry Show a Different Preservation Between Distinct Genotypes in Retinitis Pigmentosa

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Carina Kelbsch; Melanie Kempf; Ronja Jung; Friederike Kortüm; Milda Reith; Laura Kuehlewein; Susanne Kohl; Torsten Strasser; Tobias Peters; Helmut Wilhelm; Barbara Wilhelm; Krunoslav Stingl; Katarina Stingl
TAGS: genotype, pupil, pupil reaction, retinal cone, retinitis pigmentosa, rod photoreceptors, rpe65 protein, cardiac progenitor cells
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):18. https://doi.org/10.1167/iovs.64.11.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Safety and Vision Outcomes of subretinal gene supplementation therapy in PDE6A -associated Retinitis pigmentosa

Felix Friedrich Lambert Reichel; Stylianos Michalakis; Dominik M Fischer; laura kuehlewein; Tobias Peters; Susanne Kohl; Karl-Ulrich Bartz-Schmidt; Marius Ueffing; Eberhart Zrenner; Martin Biel; Katarina Stingl; Bernd Wissinger

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):782.

ARVO Annual Meeting Abstract June 2023

Optimizing Subretinal Bleb Formation in a Porcine Model for Retinal Gene Therapy

Immanuel Philipp Seitz; Tobias Peters; Bähr Andrea; Hannah Auch; Motlik Jan; Taras Ardan; Yaroslav Nemesh; Stefan Juhas; Nikolai Klymiuk; Dominik M Fischer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):778.

ARVO Annual Meeting Abstract June 2023

Evidence of potential early-stage ocular tertiary lymphoid tissue formation following high dose retinal AAV8 gene therapy

Kirsten Bucher; Daniela Süsskind; Martin Biel; Stylianos Michalakis; Karl-Ulrich Bartz-Schmidt; Tobias Peters; M Dominik Fischer; Simon J Clark

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3911.

ARVO Annual Meeting Abstract June 2023

Ciliary muscle morphology during 13-month 0.01% Atropine treatment of childhood myopia: Results of the SAM IIT trial

Torsten Strasser; Sandra Wagner; Tobias Peters; Focke Ziemssen

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3404.

Retina March 2022

Evaluation of Local Rod and Cone Function in Stargardt Disease

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Krunoslav Stingl; Carel Hoyng; Melanie Kempf; Susanne Kohl; Ronja Jung; Giulia Righetti; Laura Kühlewein; Lisa Pohl; Friederike Kortüm; Carina Kelbsch; Barbara Wilhelm; Tobias Peters; Katarina Stingl; on behalf of the SORAPRAZAN consortium
TAGS: cardiac progenitor cells, pupil reaction, retinal cone, rod photoreceptors, stargardt's disease, constriction procedure
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):6. https://doi.org/10.1167/iovs.63.3.6

Articles May 2021

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

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Eduardo Rodríguez-Bocanegra; Fabian Wozar; Immanuel P. Seitz; Felix F. L. Reichel; Alex Ochakovski; Kirsten Bucher; Barbara Wilhelm; K. Ulrich Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium
TAGS: adeno-associated virus, eye, gene therapy, injections, primates, retina, spectral domain-optical coherence tomography, surgical procedures, operative, microglia
Trans. Vis. Sci. Tech.. 2021; 10(6):15. https://doi.org/10.1167/tvst.10.6.15

Includes: Supplemental Content

Articles May 2020

Chromatic Pupil Campimetry Reveals Functional Defects in Exudative Age-Related Macular Degeneration with Differences Related to Disease Activity

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Carina Kelbsch; Jakob Lange; Helmut Wilhelm; Barbara Wilhelm; Tobias Peters; Melanie Kempf; Laura Kuehlewein; Krunoslav Stingl
TAGS: constriction procedure, exudative age-related macular degeneration, pupil, pupil constriction, pupil reaction
Trans. Vis. Sci. Tech.. 2020; 9(6):5. https://doi.org/10.1167/tvst.9.6.5

Articles December 2019

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

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Krunoslav T. Stingl; Laura Kuehlewein; Nicole Weisschuh; Saskia Biskup; Frans P. M. Cremers; M. Imran Khan; Carina Kelbsch; Tobias Peters; Marius Ueffing; Barbara Wilhelm; Eberhart Zrenner; Katarina Stingl
TAGS: eye, illness length, mutation, pupil reaction, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2019; 8(6):45. https://doi.org/10.1167/tvst.8.6.45

Articles November 2019

Objective Measurement of Local Rod and Cone Function Using Gaze-Controlled Chromatic Pupil Campimetry in Healthy Subjects

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Carina Kelbsch; Katarina Stingl; Melanie Kempf; Torsten Strasser; Ronja Jung; Laura Kuehlewein; Helmut Wilhelm; Tobias Peters; Barbara Wilhelm; Krunoslav Stingl
TAGS: constriction procedure, gaze, pupil, pupil reaction, retinal cone, rod photoreceptors
Trans. Vis. Sci. Tech.. 2019; 8(6):19. https://doi.org/10.1167/tvst.8.6.19

ARVO Annual Meeting Abstract July 2019

Systemic and intraocular administration of the liposomal formulation of the cyclic GMP analogue CN03: An exploratory safety and tolerability study in non-human primates

Francois Paquet-Durand; Tobias Peters; Pieter Gaillard; Nicolaas Schipper; Torsten Strasser; Frank Schwede; Valeria Marigo; Per A R Ekstrom; Christer Säfholm

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):257.

ARVO Annual Meeting Abstract July 2019

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

G. Alex Ochakovski; Ahmad Zhour; Laura Kuehlewein; Susanne Kohl; Andrea Rindtorff; Karl Ulrich Bartz-Schmidt; Marius Ueffing; Eberhart Zrenner; Stylianos Michalakis; Martin Biel; Bernd Wissinger; Tobias Peters; Barbara Wilhelm; M. Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2921.

ARVO Annual Meeting Abstract July 2019

Designing a clinical trial to evaluate the safety and efficacy of oral soraprazan in Stargardt Disease

Carel C B Hoyng; Andrew Lotery; Katarina Stingl; Camiel Boon; Maurizio Parodi; Patty Dhooge; Tobias Peters; Wolfgang Klein; Mario G Fsadni; Hans Müller; Oliver Jungmann

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5704.

ARVO Annual Meeting Abstract July 2019

Evaluation of pupil responses to local stimuli in Patients with retinitis pigmentosa caused by USH2A mutations

Tobias Peters; Krunoslav Stingl; Karl Ulrich Bartz-Schmidt; Laura Kuehlewein; Carina Kelbsch; Melanie Kempf; Eberhart Zrenner; Barbara Wilhelm; Katarina Stingl

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1829.

ARVO Annual Meeting Abstract July 2019

Objective Measurement of Functional Defects in Age-related Macular Degeneration by Pupil Campimetry

Carina Kelbsch; Jakob Lange; Helmut Wilhelm; Barbara Wilhelm; Tobias Peters; Melanie Kempf; Laura Kuehlewein; Krunoslav Stingl

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2295.

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Surgical approach for the implantation of a capsular ring electrode into the posterior chamber

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Host cell protein impurities are not a relevant driver of gene therapy-associated immune response

A new subretinal gene therapy for USH1C is well tolerated in wild type pigs

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

Rod and Cone Function Measured Objectively by Chromatic Pupil Campimetry Show a Different Preservation Between Distinct Genotypes in Retinitis Pigmentosa

Safety and Vision Outcomes of subretinal gene supplementation therapy in PDE6A -associated Retinitis pigmentosa

Optimizing Subretinal Bleb Formation in a Porcine Model for Retinal Gene Therapy

Evidence of potential early-stage ocular tertiary lymphoid tissue formation following high dose retinal AAV8 gene therapy

Ciliary muscle morphology during 13-month 0.01% Atropine treatment of childhood myopia: Results of the SAM IIT trial

Evaluation of Local Rod and Cone Function in Stargardt Disease

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

Chromatic Pupil Campimetry Reveals Functional Defects in Exudative Age-Related Macular Degeneration with Differences Related to Disease Activity

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

Objective Measurement of Local Rod and Cone Function Using Gaze-Controlled Chromatic Pupil Campimetry in Healthy Subjects

Systemic and intraocular administration of the liposomal formulation of the cyclic GMP analogue CN03: An exploratory safety and tolerability study in non-human primates

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

Designing a clinical trial to evaluate the safety and efficacy of oral soraprazan in Stargardt Disease

Evaluation of pupil responses to local stimuli in Patients with retinitis pigmentosa caused by USH2A mutations

Objective Measurement of Functional Defects in Age-related Macular Degeneration by Pupil Campimetry

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