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Articles April 2022

Tissue Reactivity to, and Stability of, Glaucoma Drainage Device Materials Placed Under Rabbit Conjunctiva

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Kenichi Nakamura; Tomokazu Fujimoto; Miho Okada; Kentaro Maki; Atsushi Shimazaki; Masatomo Kato; Toshihiro Inoue
TAGS: body tissue, conjunctiva, glaucoma drainage implants, oryctolagus cuniculus, silicones, stainless steel
Trans. Vis. Sci. Tech.. 2022; 11(4):9. https://doi.org/10.1167/tvst.11.4.9

Articles August 2021

Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes

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Tomokazu Fujimoto; Kei-Ichi Nakashima; Fumika Watanabe-Kitamura; Takahiro Watanabe; Kenichi Nakamura; Kentaro Maki; Atsushi Shimazaki; Masatomo Kato; Hidenobu Tanihara; Toshihiro Inoue
TAGS: blister, eye, intraocular pressure, oryctolagus cuniculus, trabeculectomy, surgical procedures, operative, conjunctiva
Trans. Vis. Sci. Tech.. 2021; 10(9):9. https://doi.org/10.1167/tvst.10.9.9

Includes: Supplemental Content

Glaucoma June 2018

YAP/TAZ Are Essential for TGF-β2–Mediated Conjunctival Fibrosis

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Akiko Futakuchi; Toshihiro Inoue; Fan-Yan Wei; Miyuki Inoue-Mochita; Tomokazu Fujimoto; Kazuhito Tomizawa; Hidenobu Tanihara
TAGS: conjunctiva, fibroblasts, fibrosis, proteins, signal transduction, verteporfin
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3069-3078. https://doi.org/10.1167/iovs.18-24258

Includes: Supplemental Content

Glaucoma April 2018

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

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Reiko Yamagishi-Kimura; Megumi Honjo; Takashi Komizo; Takashi Ono; Akiko Yagi; Jinhee Lee; Kazunori Miyata; Tomokazu Fujimoto; Toshihiro Inoue; Hidenobu Tanihara; Junko Nishida; Takatoshi Uchida; Yuka Araki; Makoto Aihara
TAGS: pilocarpine, intraocular pressure, pupil
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1844-1854. https://doi.org/10.1167/iovs.18-23900

Glaucoma April 2017

Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA)

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Akiko Futakuchi; Toshihiro Inoue; Tomokazu Fujimoto; Utako Kuroda; Miyuki Inoue-Mochita; Eri Takahashi; Saori Ohira; Hidenobu Tanihara
TAGS: vorinostat, blister, filtration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2421-2429. https://doi.org/10.1167/iovs.16-21403

ARVO Annual Meeting Abstract September 2016

Effects of ripasudil (K-115), a Rho kinase inhibitor, on the activation of human conjunctival fibroblasts

Akiko Futakuchi; Toshihiro Inoue; Tomokazu Fujimoto; Miyuki Mochita Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2929.

ARVO Annual Meeting Abstract September 2016

Vascular Endothelial Growth Factor-A Increases Aqueous humor Outflow Fcility

Tomokazu Fujimoto; Toshihiro Inoue; KEI MAKI; Miyuki Mochita Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4689.

ARVO Annual Meeting Abstract September 2016

Effects of interleukin-6 signaling activity on fibrogenic activity of human trabecular meshwork cells

Toshihiro Inoue; Miyuki Mochita Inoue; Tomokazu Fujimoto; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4693.

ARVO Annual Meeting Abstract September 2016

Four-dimensional imaging revealed influences of monocyte chemoattractant protein-1 on immune cell dynamics in the subconjunctival tissue.

Sachi Kojima; Toshihiro Inoue; Tomokazu Fujimoto; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5148.

Multidisciplinary Ophthalmic Imaging March 2016

Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy

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Sachi Kojima; Toshihiro Inoue; Junichi Kikuta; Masayuki Furuya; Ayaka Koga; Tomokazu Fujimoto; Mayumi Ueta; Shigeru Kinoshita; Masaru Ishii; Hidenobu, Tanihara
TAGS: conjunctiva, diagnostic imaging, surgical procedures, operative, wounds and injuries, mice, body tissue
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1207-1212. https://doi.org/10.1167/iovs.15-18507

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

The Effect of VEGF-A on Trabecular Meshwork and Schlemm’s Canal Endothelial Cells Permeability

Tomokazu Fujimoto; Toshihiro Inoue; Kei Maki; Sachi Kojima; Miyuki Inoue-Mochita; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2008.

ARVO Annual Meeting Abstract June 2015

Histone deacetylase inhibitor attenuates TGF-β2 induced human conjunctival fibroblast activation

Akiko Futakuchi; Toshihiro Inoue; Tomokazu Fujimoto; Utako Kuroda; Miyuki Mochita Inoue; Eri Takahashi; Kohei Shobayashi; Saori Ohira; Sachi Kojima; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2678.

ARVO Annual Meeting Abstract April 2014

Live cell imaging of F-actin in dexamethasone treated trabecular meshwork cells

Tomokazu Fujimoto; Toshihiro Inoue; Miyuki Mochita Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5679.

ARVO Annual Meeting Abstract April 2014

Effects of p38 inhibitor on TGF-β2 signal in trabecular meshwork cells

Miyuki Mochita Inoue; Toshihiro Inoue; Tomokazu Fujimoto; Nanako Awai-Kasaoka; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5691.

ARVO Annual Meeting Abstract June 2013

Identification of TGF-β2-induced Proinflammatory Cytokines Secreted from Cultured Trabecular Meshwork Cells

Miyuki Inoue; Toshihiro Inoue; Tomokazu Fujimoto; Nanaka Awai-Kasaoka; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3556.

ARVO Annual Meeting Abstract June 2013

Type I collagen-induced Epithelial Mesenchymal Transition-like Phenomenon in Trabecular Meshwork Cells

Ayako Fukushima; Eri Takahashi; Tomokazu Fujimoto; Sachi Kojima; Toshihiro Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3557.

Glaucoma October 2012

Involvement of RhoA/Rho-Associated Kinase Signal Transduction Pathway in Dexamethasone-Induced Alterations in Aqueous Outflow

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Tomokazu Fujimoto; Toshihiro Inoue; Takanori Kameda; Nanako Kasaoka; Miyuki Inoue-Mochita; Naoko Tsuboi; Hidenobu Tanihara
TAGS: dexamethasone, mechlorethamine, phosphotransferases, rhoa gtp-binding protein, signal transduction, signal transduction pathways, new mexico, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2012; 53(11):7097-7108. https://doi.org/10.1167/iovs.12-9989

Includes: Supplemental Content

Glaucoma September 2012

The Effect of Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 on Aqueous Humor Outflow Facility

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Naoko Tsuboi; Toshihiro Inoue; Motofumi Kawai; Miyuki Inoue-Mochita; Tomokazu Fujimoto; Nanako Awai-Kasaoka; Akitoshi Yoshida; Hidenobu Tanihara
TAGS: monocyte chemoattractant protein-1, aqueous humor, ligands, beta-chemokines
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6702-6707. https://doi.org/10.1167/iovs.12-10376

Glaucoma May 2012

The Effect of Rho-Associated Protein Kinase Inhibitor on Monkey Schlemm's Canal Endothelial Cells

Takanori Kameda; Toshihiro Inoue; Masaru Inatani; Tomokazu Fujimoto; Megumi Honjo; Nanako Kasaoka; Miyuki Inoue-Mochita; Nagahisa Yoshimura; Hidenobu Tanihara
TAGS: actins, calcium, calcium ions, cercopithecidae, endothelial cells, genes, permeability, protein kinase inhibitor, schlemm's canal, perfusion
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):3092-3103. https://doi.org/10.1167/iovs.11-8018

ARVO Annual Meeting Abstract March 2012

The Effects of Rho/ROCK Activation in Dexamethasone-Induced Increase of Aqueous-Outflow Resistance

Tomokazu Fujimoto; Toshihiro Inoue; Miyuki Inoue-Mochita; Takanori Kameda; Nanako Kasaoka; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3227.

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Tissue Reactivity to, and Stability of, Glaucoma Drainage Device Materials Placed Under Rabbit Conjunctiva

Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes

YAP/TAZ Are Essential for TGF-β2–Mediated Conjunctival Fibrosis

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA)

Effects of ripasudil (K-115), a Rho kinase inhibitor, on the activation of human conjunctival fibroblasts

Vascular Endothelial Growth Factor-A Increases Aqueous humor Outflow Fcility

Effects of interleukin-6 signaling activity on fibrogenic activity of human trabecular meshwork cells

Four-dimensional imaging revealed influences of monocyte chemoattractant protein-1 on immune cell dynamics in the subconjunctival tissue.

Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy

The Effect of VEGF-A on Trabecular Meshwork and Schlemm’s Canal Endothelial Cells Permeability

Histone deacetylase inhibitor attenuates TGF-β2 induced human conjunctival fibroblast activation

Live cell imaging of F-actin in dexamethasone treated trabecular meshwork cells

Effects of p38 inhibitor on TGF-β2 signal in trabecular meshwork cells

Identification of TGF-β2-induced Proinflammatory Cytokines Secreted from Cultured Trabecular Meshwork Cells

Type I collagen-induced Epithelial Mesenchymal Transition-like Phenomenon in Trabecular Meshwork Cells

Involvement of RhoA/Rho-Associated Kinase Signal Transduction Pathway in Dexamethasone-Induced Alterations in Aqueous Outflow

The Effect of Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 on Aqueous Humor Outflow Facility

The Effect of Rho-Associated Protein Kinase Inhibitor on Monkey Schlemm's Canal Endothelial Cells

The Effects of Rho/ROCK Activation in Dexamethasone-Induced Increase of Aqueous-Outflow Resistance

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