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ARVO Annual Meeting Abstract June 2024

Identification of the HDAC-regulated CDK6/ID2 signaling axis in the Th17 pathogenicity during autoimmune uveitis

Chun Zhang; Xiuxing Liu; Chenyang Gu; Wenru Su; Zhuping Xu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2990.

ARVO Annual Meeting Abstract June 2024

Dipyridamole attenuates Th17 pathogenicity by inhibiting Nampt in myeloid Cells in EAU: insights from single-cell transcriptome analysis

Binyao Chen; Zhaohao Huang; Wenru Su

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1447.

ARVO Annual Meeting Abstract June 2024

Upadacitinib in Non-Infectious Uveitis: A Comprehensive Analysis of Therapeutic Impact and Molecular Mechanisms

Zhaohao Huang; Binyao Chen; Wenru Su

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2606.

Immunology and Microbiology September 2023

Therapeutic Effects of Upadacitinib on Experimental Autoimmune Uveitis: Insights From Single-Cell Analysis

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Zhaohao Huang; Qi Jiang; Junjie Chen; Xiuxing Liu; Chenyang Gu; Tianyu Tao; Jianjie Lv; Zhaohuai Li; Zuohong Li; Wenru Su
TAGS: autoimmunity, mice, upadacitinib, uveitis, cxcr4 receptors, genes, inflammation, gene expression, biopharmaceutics classification system, signal pathway
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):28. https://doi.org/10.1167/iovs.64.12.28

Includes: Supplemental Content

Immunology and Microbiology May 2023

Identification of Hif1α as a Potential Participant in Autoimmune Uveitis Pathogenesis Using Single-Cell Transcriptome Analysis

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Lei Zhu; He Li; Rong Wang; Zhaohuai Li; Sichen Zhao; Xuening Peng; Wenru Su
TAGS: autoimmunity, mice, pathogenesis, regulatory t-lymphocytes, single-cell gene expression analysis, t-lymphocytes, uveitis, transcription, genetic, flow cytometry, rna, small cytoplasmic
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):24. https://doi.org/10.1167/iovs.64.5.24

Includes: Supplemental Content

Immunology and Microbiology July 2022

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

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Haixiang Huang; Zhuang Li; Jun Huang; Yanyan Xie; Zhiqiang Xiao; Yunwei Hu; Guanyu Chen; Minzhen Wang; Zuoyi Li; Qian Chen; Wenjie Zhu; Wenru Su; Yan Luo; Xiaoqing Chen; Dan Liang
TAGS: apolipoprotein a-i, autoimmunity, balance, device, equilibrium, immune response, mice, receptors, scavenger, regulatory t-lymphocytes, t-lymphocytes, uveitis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):23. https://doi.org/10.1167/iovs.63.8.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

M2 phenotype microglia polarization is neuroprotective in ischemic/reperfusion model of acute hypertensive glaucoma

Zhidong Li; Wenru Su; Yehong Zhuo

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1612 – A0435.

Articles March 2022

Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea

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Jianfeng Yu; Pengfei Li; Zhuang Li; Yingqi Li; Jiawei Luo; Wenru Su; Dan Liang
TAGS: cornea, macrophages, tofacitinib, allografting, stat1 gene, administration, topical, keratoplasty, rejection (psychology)
Trans. Vis. Sci. Tech.. 2022; 11(3):34. https://doi.org/10.1167/tvst.11.3.34

Immunology and Microbiology December 2021

Therapeutic Effect of IL-38 on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Cell Pathogenicity

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He Li; Lei Zhu; Rong Wang; Lihui Xie; Yuxi Chen; Runping Duan; Xiuxing Liu; Zhaohao Huang; Binyao Chen; Zhaohuai Li; Xianggui Wang; Wenru Su
TAGS: autoimmunity, mice, pathogenicity, th17 cells, uveitis, atrial premature complexes, t-lymphocytes, interleukin-23, rna, small cytoplasmic, interleukin-17
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):31. https://doi.org/10.1167/iovs.62.15.31

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Single-cell Chromatin Accessibility Identifies Pathogenic Regulatory Programs in Vogt-Koyanagi-Harada Disease and Behcet’s Disease

Wen Shi; Jinguo Ye; Wenru Su; Yingfeng Zheng

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1998.

ARVO Annual Meeting Abstract July 2019

Tofacitinibhas preventive and therapeutic effects for uveitis in mice model

YICHEN XIAO; Wenru Su

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):793.

Cornea August 2018

Hemin Promotes Corneal Allograft Survival Through the Suppression of Macrophage Recruitment and Activation

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Ye Dai; Xiaokang Cheng; Jianfeng Yu; Xiaoqing Chen; Yichen Xiao; Fen Tang; Yingqi Li; Shangtao Wan; Wenru Su; Dan Liang
TAGS: allografting, cornea, hemin, macrophages, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3952-3962. https://doi.org/10.1167/iovs.17-23327

ARVO Annual Meeting Abstract July 2018

The activation of mGluR5 against retinal neuron death in retinal ischemia/reperfusion model

Zuohong Li; Yu Jia; Wenru Su; Yehong Zhuo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6148.

ARVO Annual Meeting Abstract July 2018

Baicalin modulates Treg/Teff cell balance to alleviate autoimmune uveitis via activating aryl hydrocarbon receptor

Wenjie Zhu; Dan Liang; Wenru Su

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2543.

ARVO Annual Meeting Abstract July 2018

Caspase-8 Promotes Inflammation-Induced Lymphangiogenesis and Allograft Rejection in the Cornea

Wenru Su; Xiaoqing Chen; Yichen Xiao; Song Guo Zheng; Dan Liang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2575.

Immunology and Microbiology October 2015

Doxycycline Attenuates Endotoxin-Induced Uveitis by Prostaglandin E2-EP4 Signaling

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Jingwen Huang; Wenru Su; Xiaoqing Chen; Xiaokang Cheng; Ye Dai; Longhui Han; Dan Liang
TAGS: doxycycline, signal transduction, uveitis, endotoxins, prostaglandins
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6686-6693. https://doi.org/10.1167/iovs.15-17045

Biochemistry and Molecular Biology January 2013

Doxycycline-Mediated Inhibition of Corneal Angiogenesis: An MMP-Independent Mechanism

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Wenru Su; Zhanrong Li; Fan Li; Xiaoqing Chen; Qian Wan; Dan Liang
TAGS: doxycycline, vascular endothelial growth factor a, angiogenesis, corneal neovascularization, choroidal neovascularization, nitric oxide synthase
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):783-788. https://doi.org/10.1167/iovs.12-10323

Cornea November 2011

Doxycycline Enhances the Inhibitory Effects of Bevacizumab on Corneal Neovascularization and Prevents Its Side Effects

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Wenru Su; Zhanrong Li; Yongping Li; Miaoli Lin; Lin Yao; Yi Liu; Zixin He; Chuanbin Wu; Dan Liang
TAGS: adverse effects, bevacizumab, burns, choroidal neovascularization, cornea, corneal neovascularization, doxycycline, fibroblast growth factor 2, alkalies, matrix metalloproteinases
Invest. Ophthalmol. Vis. Sci.. 2011; 52(12):9108-9115. https://doi.org/10.1167/iovs.11-7255

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Identification of the HDAC-regulated CDK6/ID2 signaling axis in the Th17 pathogenicity during autoimmune uveitis

Dipyridamole attenuates Th17 pathogenicity by inhibiting Nampt in myeloid Cells in EAU: insights from single-cell transcriptome analysis

Upadacitinib in Non-Infectious Uveitis: A Comprehensive Analysis of Therapeutic Impact and Molecular Mechanisms

Therapeutic Effects of Upadacitinib on Experimental Autoimmune Uveitis: Insights From Single-Cell Analysis

Identification of Hif1α as a Potential Participant in Autoimmune Uveitis Pathogenesis Using Single-Cell Transcriptome Analysis

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

M2 phenotype microglia polarization is neuroprotective in ischemic/reperfusion model of acute hypertensive glaucoma

Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea

Therapeutic Effect of IL-38 on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Cell Pathogenicity

Single-cell Chromatin Accessibility Identifies Pathogenic Regulatory Programs in Vogt-Koyanagi-Harada Disease and Behcet’s Disease

Tofacitinibhas preventive and therapeutic effects for uveitis in mice model

Hemin Promotes Corneal Allograft Survival Through the Suppression of Macrophage Recruitment and Activation

The activation of mGluR5 against retinal neuron death in retinal ischemia/reperfusion model

Baicalin modulates Treg/Teff cell balance to alleviate autoimmune uveitis via activating aryl hydrocarbon receptor

Caspase-8 Promotes Inflammation-Induced Lymphangiogenesis and Allograft Rejection in the Cornea

Doxycycline Attenuates Endotoxin-Induced Uveitis by Prostaglandin E2-EP4 Signaling

Doxycycline-Mediated Inhibition of Corneal Angiogenesis: An MMP-Independent Mechanism

Doxycycline Enhances the Inhibitory Effects of Bevacizumab on Corneal Neovascularization and Prevents Its Side Effects

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