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Clinical and Epidemiologic Research June 2023

Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

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Yuanyuan Wang; Mengqi Liu; Zhu Xie; Pengqi Wang; Xiang Li; Xinyuan Yao; Jinmin Tian; Yang Han; Xiangqin Chen; Zhiqiang Xu; Xinjie Mao; Xiangtian Zhou; Jia Qu; Hao Wu
TAGS: chinese (other dialects), chinese people, choroidal circulation, cortical blindness, eye, perfusion, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):7. doi: https://doi.org/10.1167/iovs.64.7.7

Includes: Supplemental Content

Retina May 2023

Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

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Jiaxing Zhou; Sen Lin; Qiumei Hu; Xue Li; Xi Chen; Linlin Luo; Shiyang Ye; Wei Liu; Jian Ye
TAGS: insulin-like growth factor i, macrophage-1 antigen, microglia, phagocytosis, optic nerve injuries
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):7. doi: https://doi.org/10.1167/iovs.64.5.7

Includes: Supplemental Content

Lens April 2023

Endoplasmic Reticulum Stress and the Lysosomal Pathway Play Crucial Roles in the Progression of βB2-Crystallin Mutation-Induced Congenital Cataracts in Mice

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Wei Xiao; Weimin Yang; Xinyu Zhang; Xiaoqian Deng; Xiaoyun Chen
TAGS: congenital cataract, crystallins, lens (device), lens, crystalline, mice, mutation, stress, cataract, lysosomes, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):34. doi: https://doi.org/10.1167/iovs.64.4.34

Includes: Supplemental Content

Lens April 2023

Plasmin-Induced Lens Epithelial Cells Detachment for the Reduction of Posterior Capsular Opacification

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Xiaomei Bai; Jingli Liang; Yufan Yin; Yuanfeng Jiang; Fangyu Zhao; Fang Tian; Xiteng Chen; Lijie Dong; Shaochong Bu
TAGS: plasmin
Trans. Vis. Sci. Tech.. 2023; 12(4):23. doi: https://doi.org/10.1167/tvst.12.4.23

Includes: Supplemental Content

Cornea April 2023

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

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Xiao Wang; Zedu Cui; Xi Chen; Qian Luo; Zihua Jiang; Xuan Liu; Yuke Huang; Jingyi Jiang; Shuilian Chen; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: choroidal neovascularization, cxcr4 receptors, corneal neovascularization, hypoxia, cornea
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):10. doi: https://doi.org/10.1167/iovs.64.4.10

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2023

The RNA m 5 C Methylase NSUN2 Modulates Corneal Epithelial Wound Healing

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Guangying Luo; Weiwei Xu; Xiaoyan Chen; Wenji Xu; Shuai Yang; Jiao Wang; Yong Lin; Peter S. Reinach; Dongsheng Yan
TAGS: rna, methyltransferase, cornea, wound healing, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):5. doi: https://doi.org/10.1167/iovs.64.3.5

Includes: Supplemental Content

Genetics February 2023

De Novo Mutations Contributes Approximately 7% of Pathogenicity in Inherited Eye Diseases

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Wei Li; Xiang-Dong He; Zheng-Tao Yang; Dong-Ming Han; Yan Sun; Yan-Xian Chen; Xiao-Tong Han; Si-Cheng Guo; Yu-Ting Ma; Xin Jin; Huan-Ming Yang; Ya Gao; Zhuo-Shi Wang; Jian-Kang Li; Wei He
TAGS: de novo mutation, epileptiform discharges, eye diseases, genes, improvised explosive devices, pathogenicity, proband, marfan syndrome, ectopia lentis, parent
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):5. doi: https://doi.org/10.1167/iovs.64.2.5

Includes: Supplemental Content

Artificial Intelligence January 2023

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

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Xiaoming Chen; Ying Xue; Xiaoyan Wu; Yi Zhong; Huiying Rao; Heng Luo; Zuquan Weng
TAGS: deep learning, learning, optical coherence tomography, retinal diseases, screening
Trans. Vis. Sci. Tech.. 2023; 12(1):29. doi: https://doi.org/10.1167/tvst.12.1.29

Includes: Supplemental Content

Retina October 2022

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

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Shuilian Chen; Xi Chen; Ping Zhang; Shuxia Chen; Xiao Wang; Qian Luo; Zedu Cui; Yuke Huang; Linxi Wan; Xiangtao Hou; Huan Yao; Xuan Liu; Anqi He; Zihua Jiang; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: bioinformatics, genes, retinoblastoma, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):28. doi: https://doi.org/10.1167/iovs.63.11.28

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2022

Longitudinal Changes in Lens Thickness and Lens Power Among Persistent Non-Myopic and Myopic Children

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Xiaotong Han; Ruilin Xiong; Ling Jin; Qianyun Chen; Decai Wang; Shida Chen; Xiang Chen; Jason Ha; Yuting Li; Yabin Qu; Rong Lin; Mingguang He; Ian G. Morgan; Yangfa Zeng; Yizhi Liu
TAGS: child, eye development, lens, crystalline, myopia, persistence, follow-up
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):10. doi: https://doi.org/10.1167/iovs.63.10.10

Includes: Supplemental Content

Article September 2022

Transcranial random noise stimulation and exercise do not modulate ocular dominance plasticity in adults with normal vision

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Xiaoxin Chen; Kennedy Hall; William R. Bobier; Benjamin Thompson; Arijit Chakraborty
TAGS: adult, emmetropia, exercise, noise, ocular dominance
Journal of Vision. 2022; 22(10):14. doi: https://doi.org/10.1167/jov.22.10.14

Includes: Supplemental Content

Biochemistry and Molecular Biology September 2022

Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts

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Jiale Diao; Xinxin Chen; Pei Mou; Xiaoye Ma; Ruili Wei
TAGS: berberine, fibroblasts, fibrosis, graves' ophthalmopathy, tissue remodeling, inflammation, western blotting, proteins, enzyme-linked immunosorbent assay, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):6. doi: https://doi.org/10.1167/iovs.63.10.6

Includes: Supplemental Content

Immunology and Microbiology July 2022

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

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Haixiang Huang; Zhuang Li; Jun Huang; Yanyan Xie; Zhiqiang Xiao; Yunwei Hu; Guanyu Chen; Minzhen Wang; Zuoyi Li; Qian Chen; Wenjie Zhu; Wenru Su; Yan Luo; Xiaoqing Chen; Dan Liang
TAGS: apolipoprotein a-i, autoimmunity, balance, device, equilibrium, immune response, mice, receptors, scavenger, regulatory t-lymphocytes, t-lymphocytes, uveitis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):23. doi: https://doi.org/10.1167/iovs.63.8.23

Includes: Supplemental Content

Retina June 2022

Irisin Attenuates Pathological Neovascularization in Oxygen-Induced Retinopathy Mice

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Jieqiong Zhang; Zhifei Liu; Haoqian Wu; Xi Chen; Qiumei Hu; Xue Li; Linlin Luo; Shiyang Ye; Jian Ye
TAGS: irisin, mice, neovascularization, pathologic, retinal diseases, oxygen, astrocytes
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):21. doi: https://doi.org/10.1167/iovs.63.6.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Short-term treatment effects on retinal microanatomy in preterm infants with severe retinopathy of prematurity

Shwetha Mangalesh; Xi Chen; Du Tran-viet; Neeru Sarin; Katrina Winter; S. Grace Prakalapakorn; Sharon Freedman; Cynthia A Toth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4192 – F0252. doi:

ARVO Annual Meeting Abstract June 2022

Enabling acquisition of optical coherence tomography angiography in cardiac surgery and intensive care

Ryan Imperio; Du Tran-viet; Shwetha Mangalesh; Christian Viehland; Joseph A. Izatt; Xi Chen; Cynthia A Toth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2962 – F0116. doi:

ARVO Annual Meeting Abstract June 2022

400 kHz Handheld OCTA System for Bedside Imaging of Infant

Christian Viehland; Xi Chen; Du Tran-viet; Shwetha Mangalesh; Ryan Imperio; Cynthia A Toth; Joseph A. Izatt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2906 – F0059. doi:

ARVO Annual Meeting Abstract June 2022

Consistent Immunomodulatory Genes and the Competitive Endogenous RNA Networks in Keratoconus among Populations

Xi Chen; Chang Liu; Jing Zhuang; Keming Yu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2411 – A0214. doi:

ARVO Annual Meeting Abstract June 2022

IL-37 prevents corneal barrier disruption by inhibiting TNF-α/CTSS signaling in primary human corneal epithelial cells under hyperosmotic stress

De-Quan Li; Yun Zhang; Jinmiao Li; Xin Chen; Stephen C Pflugfelder; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1977 – A0307. doi:

ARVO Annual Meeting Abstract June 2022

Ocular Characteristics and Disease Progression in a Preclinical Model of Batten Disease

Ashley Rowe; Xin Chen; Yacine Issioui; Thomas Dong; Yuhui Hu; Steven Gray; Katherine J Wert

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2610 – F0493. doi:

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Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

Endoplasmic Reticulum Stress and the Lysosomal Pathway Play Crucial Roles in the Progression of βB2-Crystallin Mutation-Induced Congenital Cataracts in Mice

Plasmin-Induced Lens Epithelial Cells Detachment for the Reduction of Posterior Capsular Opacification

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

The RNA m 5 C Methylase NSUN2 Modulates Corneal Epithelial Wound Healing

De Novo Mutations Contributes Approximately 7% of Pathogenicity in Inherited Eye Diseases

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

Longitudinal Changes in Lens Thickness and Lens Power Among Persistent Non-Myopic and Myopic Children

Transcranial random noise stimulation and exercise do not modulate ocular dominance plasticity in adults with normal vision

Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

Irisin Attenuates Pathological Neovascularization in Oxygen-Induced Retinopathy Mice

Short-term treatment effects on retinal microanatomy in preterm infants with severe retinopathy of prematurity

Enabling acquisition of optical coherence tomography angiography in cardiac surgery and intensive care

400 kHz Handheld OCTA System for Bedside Imaging of Infant

Consistent Immunomodulatory Genes and the Competitive Endogenous RNA Networks in Keratoconus among Populations

IL-37 prevents corneal barrier disruption by inhibiting TNF-α/CTSS signaling in primary human corneal epithelial cells under hyperosmotic stress

Ocular Characteristics and Disease Progression in a Preclinical Model of Batten Disease

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