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ARVO Annual Meeting Abstract June 2025

The 12-HETE/GPR31 Axis as a Novel Therapeutic Target for Diabetic Retinopathy

Mohamed Moustafa; Xiao Zhang; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6340.

ARVO Annual Meeting Abstract June 2025

Clinical Studies of Gene Therapy FT-003 for both Naïve and Treated nAMD via a Single Intravitreal Injection

Xiaorong Li; Dongjun Xing; Boshi Liu; Yan Shao; Peirong Lu; Wei Xia; Weihong Yu; Rongping Dai; Xiao Zhang; Jingbo Li; Xianlong Wang; Hua Song; Li Huang; Minghui Xue; Chao Ren; Xinyan Li

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):680.

ARVO Annual Meeting Abstract June 2025

Activation of Bone Morphogenetic Protein Receptor (Bmpr1a) Induces Fibrovascular Changes in Mouse Retina

Sonali Sharma; Ikbal Karkoukli; Alee Assaf; Sergio Bermudez; Youstina Guirguis; Mohamed Moustafa; Xiao Zhang; Yuji Mishina; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):884.

ARVO Annual Meeting Abstract June 2025

Safety, Tolerability and Efficacy of Intravitreal AM712 for Neovascular Age-Related Macular Degeneration (CONQUER)

Vrinda Hershberger; David Ryan Lally; Eric W Schneider; Charles Clifton Wykoff; Richard G Lane; David M Brown; Roger A Goldberg; Nikolas J London; Jeffrey S Heier; Peter Kaiser; Xiaozhe Zhang; Fiona Ma; Yusong Xia; Wei Wang; Billy Xin; Michelle Zhang; Yutao Ma

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):693.

ARVO Annual Meeting Abstract June 2025

Fedratinib related ocular inflammatory diseases in patients with myelofibrosis: An analysis from TriNetX database

Nathan Shows; Negin Yavari; Dalia El Feky; Jia-Horung Hung; Aim-On Saengsirinavin; Azadeh Mobasserian; Amir Akhavanrezayat; Isabel Sendino; Xiaoyan Zhang; Ngoc Trong Tuong Than; Anh Ngoc Tram Tran; Bhargavi Vatte; Cigdem Yasar; Yue Bai; JINGLI GUO; Doran Spencer; Quan Dong Nguyen; Chris Or

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2873.

ARVO Annual Meeting Abstract June 2025

Long-term efficacy and tolerability of subcutaneous repository corticotropin injection in patients with ocular inflammatory diseases

Anh Ngoc Tram Tran; Negin Yavari; Aim-On Saengsirinavin; Amir Akhavanrezayat; Jia-Horung Hung; Isabel Sendino; Azadeh Mobasserian; Xiaoyan Zhang; mohammad bagher Rajabi; Ngoc Than; Dalia El Feky; Bhargavi Vatte; Jingli Guo; Irmak Karaca; Chris Or; Quan Dong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5909.

ARVO Annual Meeting Abstract June 2025

Real-world 6-month outcomes of repository corticotropin injection in noninfectious posterior uveitis unresponsive to immunomodulatory therapy

Ngoc Than; Jia-Horung Hung; Frances Andrea Anover; Amir Akhavanrezayat; Aim-on Saengsirinavin; Xiaoyan Zhang; Negin Yavari; Azadeh Mobasserian; Dalia Elfeqi; Anh Ngoc Tram Tran; Albert Bromeo; Zheng-Xian Thng; JINGLI GUO; Hien Luong Doan; Chris Or; Quan Dong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5908.

ARVO Annual Meeting Abstract June 2025

Loss of H3.3 from retinal progenitors affects chromatin remodeling and acquisition of specific cell fates

Philip Ruzycki; Ellen G Harding; Kennedy H Turner; Sohini Rebba; Xiaodong Zhang; Elizabeth Byrne; Francisca Vitorino; Benjamin Garcia; Pierre Mattar

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5147.

ARVO Annual Meeting Abstract June 2025

Heterozygous depletion of H3f3b results in rod photoreceptor dysfunction

Ellen G Harding; Kennedy H Turner; Elizabeth Byrne; Sohini Rebba; Xiaodong Zhang; Pierre Mattar; Philip Ruzycki

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5143.

ARVO Annual Meeting Abstract June 2025

Correlation of Schlemm’s Canal and Collector Channels between OCT-Angiography and Histology in Aqueous Angiography-defined High-Flow and Low-Flow regions

Xiaowei Zhang; Daniel Wanderer; Hao Zhang; Clemens Strohmaier; Robert Weinreb; Alex S Huang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):819.

ARVO Annual Meeting Abstract June 2025

Active DNA demethylation is required for photoreceptors fate specification and function

Ismael Hernandez-Nunez; Alaina Urman; Xiaodong Zhang; William Jacob; Qiang Li; Fengbiao Mao; Andi Cani; Shiming Chen; Meelad Dawlaty; Rajesh Rao; Philip Ruzycki; John Edwards; Brian Clark

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):472.

ARVO Annual Meeting Abstract June 2025

Age-related Changes in Anterior Segment Biometric Measurements in New Zealand White Rabbits

Sudan Puri; Vivian Trenti; James Lee; Marcela Duran; Walter Collette; Sujata Rijal; Hannah Gill; Jenny Walters; Yesica Chaparro; Stephanie Peters; Xiaohui Zhang; Sara Mangosing; Matthew Lyulkin; Sandeep Kumar; Glenwood G Gum

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4443.

ARVO Annual Meeting Abstract June 2025

NEAT1 in iPSC-derived cells triggers cell fate conversion of trabecular meshwork

Wei Zhu; Xiaoyan Zhang; Bin Xu; Pengchao Feng

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3008.

ARVO Annual Meeting Abstract June 2025

Efficacy, Immunogenicity and Safety of Various Biosimilar Tumor Necrosis Factor Inhibitors in Ocular inflammatory diseases

Dalia Elfeqi; Negin Yavari; Azadeh Mobasserian; Amir Akhavanrezayat; Ngoc Than; Aim-On Saengsirinavin; Jia-Horung Hung; Cigdem Yasar; Xiaoyan Zhang; Yue Bai; JINGLI GUO; Anh Ngoc Tram Tran; Nathan Shows; mohammad bagher Rajabi; Christopher Or; Quan Dong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):194.

ARVO Annual Meeting Abstract June 2025

Association Between Cancer and Peripheral Drusen-like Deposits in Patients with Retinal Vasculitis

Cigdem Yasar; Xiaoyan Zhang; Amir Akhavanrezayat; Yue Bai; Ngoc Than; Anh Ngoc Tram Tran; Azadeh Mobasserian; JINGLI GUO; Negin Yavari; Alyce Oh; Nathan Shows; Dalia El Feky; Frances Andrea Anover; Chris Or; Quan Dong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5500.

ARVO Annual Meeting Abstract June 2025

Glycosaminoglycans demonstrate segmental differences in low-flow versus high-flow human trabecular meshwork

Collin Else; Kamalu Park; Savanna Pflugmacher; Xiaowei Zhang; Daniel Wanderer; Alex S Huang; Jeffrey Esko; Christopher Toomey

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):845.

ARVO Annual Meeting Abstract June 2025

Tolerability of ocular buffers utilized to deliver cell and gene therapies into the posterior segment of the eye

Sandeep Kumar; Xiaohui Zhang; Sudan Puri; James Lee; Hannah Gill; Yesica Chaparro; Vivian Trenti; Stephanie Peters; Jenny Walters; Walter Collette; Sara Mangosing; Carly Boyd; Sujata Rijal; Matthew Lyulkin; Glenwood G Gum

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1623.

ARVO Annual Meeting Abstract June 2025

In vivo characterization of Rotenone-induced optic neuropathy in a mouse model

Xiaohui Zhang; James Lee; Sudan Puri; Hannah Gill; Kenneth Huang; Sujata Rijal; Yesica Chaparro; Vivian Trenti; Stephanie Peters; Walter Collette; Jenny Walters; Glenwood G Gum; Sandeep Kumar

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2439.

ARVO Annual Meeting Abstract June 2025

Optic Nerve Vasculature and Countermeasure Assessment in a Ground-based Bedrest Analogue of Spaceflight-Associated Neuro-ocular Syndrome (SANS)

Daniel Wanderer; Ye He; Xiaowei Zhang; Seung Hyen Lee; Matthew Poczatek; Rustum Karanjia; Stuart Lee; Ken Marion; Edwin Mulder; Claudia Stern; SriniVas R Sadda; Steven Laurie; Brandon Macias; Cambria O'Grady; Alex S Huang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3181.

Retina May 2025

Exploring Therapeutic Targets for Age-Related Macular Degeneration From Circulating Proteins to Plasma Metabolites in the European Population

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Chengming Chen; Yanyan Lan; Weiming Yan; Xiaohong Zhang; Tian Li; Jing Han
TAGS: age-related macular degeneration, metabolites, plasma, proteins, european continental ancestry group
Trans. Vis. Sci. Tech.. 2025; 14(5):8. https://doi.org/10.1167/tvst.14.5.8

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The 12-HETE/GPR31 Axis as a Novel Therapeutic Target for Diabetic Retinopathy

Clinical Studies of Gene Therapy FT-003 for both Naïve and Treated nAMD via a Single Intravitreal Injection

Activation of Bone Morphogenetic Protein Receptor (Bmpr1a) Induces Fibrovascular Changes in Mouse Retina

Safety, Tolerability and Efficacy of Intravitreal AM712 for Neovascular Age-Related Macular Degeneration (CONQUER)

Fedratinib related ocular inflammatory diseases in patients with myelofibrosis: An analysis from TriNetX database

Long-term efficacy and tolerability of subcutaneous repository corticotropin injection in patients with ocular inflammatory diseases

Real-world 6-month outcomes of repository corticotropin injection in noninfectious posterior uveitis unresponsive to immunomodulatory therapy

Loss of H3.3 from retinal progenitors affects chromatin remodeling and acquisition of specific cell fates

Heterozygous depletion of H3f3b results in rod photoreceptor dysfunction

Correlation of Schlemm’s Canal and Collector Channels between OCT-Angiography and Histology in Aqueous Angiography-defined High-Flow and Low-Flow regions

Active DNA demethylation is required for photoreceptors fate specification and function

Age-related Changes in Anterior Segment Biometric Measurements in New Zealand White Rabbits

NEAT1 in iPSC-derived cells triggers cell fate conversion of trabecular meshwork

Efficacy, Immunogenicity and Safety of Various Biosimilar Tumor Necrosis Factor Inhibitors in Ocular inflammatory diseases

Association Between Cancer and Peripheral Drusen-like Deposits in Patients with Retinal Vasculitis

Glycosaminoglycans demonstrate segmental differences in low-flow versus high-flow human trabecular meshwork

Tolerability of ocular buffers utilized to deliver cell and gene therapies into the posterior segment of the eye

In vivo characterization of Rotenone-induced optic neuropathy in a mouse model

Optic Nerve Vasculature and Countermeasure Assessment in a Ground-based Bedrest Analogue of Spaceflight-Associated Neuro-ocular Syndrome (SANS)

Exploring Therapeutic Targets for Age-Related Macular Degeneration From Circulating Proteins to Plasma Metabolites in the European Population

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