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Low Vision March 2025

EFEMP1-Mediated Regulation of Choroidal Vascular Dysfunction in Myopia: Insights Into the FOXO3/VEGFA Pathway as a Therapeutic Target

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Wen-Qing Shi; Bing Li; Yuting Shao; Wenting Han; Yule Xu; Qing Jiang; Shen Qu; Xiaodong Zhou; Yanlong Bi
TAGS: forkhead box protein o3, myopia, pathophysiology, caviidae, regulation, choroid, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):43. https://doi.org/10.1167/iovs.66.3.43

Includes: Supplemental Content

Retinal Cell Biology March 2025

Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling

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Xiaodi Zhou; Xiaoxiao Xu; Qiong Wang; Yanting Lai; Linyan Zhang; Yunfeng Lin; Xiaoyan Ding; Limei Sun
TAGS: endothelial cells, hypoxia, notch1 gene, retinal neovascularization, rna, small interfering, signal transduction, proteins, neovascularization, pathologic, ischemia, fluorescence
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):39. https://doi.org/10.1167/iovs.66.3.39

Cornea February 2025

Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation

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Xiao Zhou; Lingjuan Xu; Yongyao Tan; Wei Wang; Xiaoyu Huang; Guigang Li
TAGS: language morphology, morphology, phenotype, translocation (genetics), diffuse idiopathic skeletal hyperostosis, cornea, stem cells, proteins, western blotting, patient isolation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):43. https://doi.org/10.1167/iovs.66.2.43

Includes: Supplemental Content

Retina February 2025

Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

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Xiaoyan Ding; Xiaodi Zhou; Xinyu Liu; Yanting Lai; Wenjia Yan; Yizhe Cheng; Aohan Hou; Limei Chen; Limei Sun
TAGS: angiogenesis, hypoxia, mice, neovascularization, pathologic, 1-phosphatidylinositol 3-kinase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):40. https://doi.org/10.1167/iovs.66.2.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Wide-Field Swept-source structural OCT and OCT Angiography in Inherited Retinal Dystrophies

Xiao Zhou; Nida Wongchaisuwat; Guangru Ben Liang; Tristan T Hormel; Lesley Everett; Paul Yang; Mark E Pennesi; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5495.

ARVO Annual Meeting Abstract June 2024

Impact of Dietary Supplement Intake on the Progression of Stargardt Disease

Christopher Turski; Cesar Estrada Puente; Kubra Sarici; Xiao Zhou; Ramiro S Maldonado

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD82.

ARVO Annual Meeting Abstract June 2024

Visualizing Retinal Interlayer Communicating Capillaries Using Optical Coherence Tomography Angiography

Bailee Alonzo; Yuxin Xia; Yaping Shi; Xiao Zhou; Ruikang K Wang; Amir H Kashani

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3425.

ARVO Annual Meeting Abstract June 2024

Longitudinal Analysis of Ellipsoid Zone loss in patients with Retinitis Pigmentosa

Kubra Sarici; Cesar Estrada Puente; Xiao Zhou; Ramiro S Maldonado

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1019.

ARVO Annual Meeting Abstract June 2024

HDAC4 modulates trabecular meshwork cells PANoptosis through deacetylation modification of caspases in primary open-angle glaucoma

Xiaoyu Zhou; xinyue zhang; Jiahao Xu; Xuanchu Duan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3556.

ARVO Annual Meeting Abstract June 2024

A Novel Adjustable PHBV Basement Film for Enhancing the Efficacy of Glaucoma Surgery by Inhibiting Scar Formation

Xuanchu Duan; Xiaoyu Zhou; Jiahao Xu; xinyue zhang; Yang Zhao

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2130.

ARVO Annual Meeting Abstract June 2024

Intraocular Pressure Reduction Treatment through a Sustained-Release System Loaded with LBN in a Novel Nanoscale Zinc/Iron Mixed-Metal MOF-74

Jiahao Xu; Xiaoyu Zhou; xinyue zhang; Xuanchu Duan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1908.

Retina October 2023

Silibinin Prevents TGFβ-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation

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Xinqi Ma; Yiyu Xie; Yajun Gong; Chuxuan Hu; Kairui Qiu; Yao Yang; Huangxuan Shen; Xiaolai Zhou; Chongde Long; Xiaofeng Lin
TAGS: epithelial to mesenchymal transition, phosphorylation, silibinin, smad3 gene, stat3 protein, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):47. https://doi.org/10.1167/iovs.64.13.47

Includes: Supplemental Content

Retina October 2023

Pupillary Light Reflex and Multimodal Imaging in Patients With Central Serous Chorioretinopathy

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Xiaoyin Zhou; Hisashi Fukuyama; Takaaki Sugisawa; Yoichi Okita; Hiroyuki Kanda; Yuki Yamamoto; Takashi Araki; Fumi Gomi
TAGS: central serous chorioretinopathy, pupil light reflex, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):28. https://doi.org/10.1167/iovs.64.13.28

ARVO Imaging in the Eye Conference Abstract June 2023

Retinal capillary velocimetry based on optical coherence tomography angiography scan protocols

Yuxin Xia; Xiao Zhou; Zahra Nafar; Qinqin Zhang; Giovanni Gregori; Philip J. Rosenfeld; Amir H Kashani; Kasra Rezaei; Ruikang Wang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0070.

ARVO Imaging in the Eye Conference Abstract June 2023

Comparison of two retinal tracking methods using infrared-reflectance (IR) fundus images

Homayoun Bagherinia; Qinqin Zhang; Xiao Zhou; Kique Romero; Ruikang Wang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0056.

ARVO Annual Meeting Abstract June 2023

OCTA in iris and sclera with anterior segment add-on lens and tracking

Zahra Nafar; Thomas Callan; Homayoun Bagherinia; Andrew Chen; Karine Duarte Bojikian; Philip P Chen; Ruikang K Wang; Xiao Zhou

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3386.

ARVO Annual Meeting Abstract June 2023

Retinal vascular response to dark adaptation using a functional optical coherence tomography angiography

Suman Adhikari; Yaping Shi; Xiao Zhou; Ruikang K Wang; Amir H. Kashani

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3384.

ARVO Annual Meeting Abstract June 2023

Macular changes on optical coherence tomography angiography following belzutifan therapy in patients with Von-Hippel Lindau disease

Mutaz Al-Nawaflh; Ayman G. Elnahry; Elvira Agron; Jie Lu; Yuxuan Cheng; Xiao Zhou; Sunil Bellur; Catherine Cukras; Tiarnan D L Keenan; Ruikang K Wang; Emily Y. Chew; Alisa Thavikulwat

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2307.

ARVO Annual Meeting Abstract June 2023

Retinal capillary and choriocapillaris velocimetry in normal eyes by optical coherence tomography angiography

Xiao Zhou; Qinqin Zhang; Zahra Nafar; Sujata Rijal; Mengxi Shen; Kasra A Rezaei; Giovanni Gregori; Philip J Rosenfeld; Amir H. Kashani; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2538.

ARVO Annual Meeting Abstract June 2023

Fully automated segmentation and quantification of the macular pigment burden detected on SS-OCTA and SD-OCT scans

Yuxuan Cheng; Gissel Herrera; Jie Lu; Jianqing Li; Ziyu Liu; Mengxi Shen; Qinqin Zhang; Jeremy Liu; Xiao Zhou; Farhan E. Hiya; Yingying Shi; Hao Zhou; Giovanni Gregori; Philip J Rosenfeld; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):320.

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EFEMP1-Mediated Regulation of Choroidal Vascular Dysfunction in Myopia: Insights Into the FOXO3/VEGFA Pathway as a Therapeutic Target

Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling

Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation

Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

Wide-Field Swept-source structural OCT and OCT Angiography in Inherited Retinal Dystrophies

Impact of Dietary Supplement Intake on the Progression of Stargardt Disease

Visualizing Retinal Interlayer Communicating Capillaries Using Optical Coherence Tomography Angiography

Longitudinal Analysis of Ellipsoid Zone loss in patients with Retinitis Pigmentosa

HDAC4 modulates trabecular meshwork cells PANoptosis through deacetylation modification of caspases in primary open-angle glaucoma

A Novel Adjustable PHBV Basement Film for Enhancing the Efficacy of Glaucoma Surgery by Inhibiting Scar Formation

Intraocular Pressure Reduction Treatment through a Sustained-Release System Loaded with LBN in a Novel Nanoscale Zinc/Iron Mixed-Metal MOF-74

Silibinin Prevents TGFβ-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation

Pupillary Light Reflex and Multimodal Imaging in Patients With Central Serous Chorioretinopathy

Retinal capillary velocimetry based on optical coherence tomography angiography scan protocols

Comparison of two retinal tracking methods using infrared-reflectance (IR) fundus images

OCTA in iris and sclera with anterior segment add-on lens and tracking

Retinal vascular response to dark adaptation using a functional optical coherence tomography angiography

Macular changes on optical coherence tomography angiography following belzutifan therapy in patients with Von-Hippel Lindau disease

Retinal capillary and choriocapillaris velocimetry in normal eyes by optical coherence tomography angiography

Fully automated segmentation and quantification of the macular pigment burden detected on SS-OCTA and SD-OCT scans

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