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Retina September 2024

Preoperative OCT-Derived Nasal Perifoveal Retinal Nerve Fiber Layer Thickness Predictively Correlates Long-Term Visual Acuity Post Oil Removal Surgery

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Shuoyang Wang; Zilin Wang; Huixun Jia; Hong Wang; Tong Li; Junran Sun; Xiaodong Sun
TAGS: nose, preoperative care, retinal nerve fiber layer, silicone oils, surgical procedures, operative, visual acuity, risk factors
Trans. Vis. Sci. Tech.. 2024; 13(9):16. https://doi.org/10.1167/tvst.13.9.16

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Clinical and Molecular Characterization of AIPL1 -Associated Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Tong Li; Quan Zhang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):628.

ARVO Annual Meeting Abstract June 2024

Comparable efficacy with aflibercept 8 mg at extended dosing intervals beyond q16 versus 2 mg q8 in Asian patients with nAMD in PULSAR through Week 96

Xiaodong Sun; Shih-Jen Chen; xin Zhang; Andrea Schulze; Tobias Machewitz; Min Zhao; Sergio Leal

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):220.

ARVO Annual Meeting Abstract June 2024

Choroidal vascularity index (CVI) changes associated with lesion activity of polypoidal choroidal vasculopathy (PCV)

Qiyu Bo; Xiaoxu Huang; Jieqiong Chen; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2304.

ARVO Annual Meeting Abstract June 2024

Gene therapy restores vision and delays degeneration in the CNGA1 -/- mouse model of retinitis pigmentosa

Xiaoling Wan; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5357.

ARVO Annual Meeting Abstract June 2024

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Junran Sun; Yang Liu; Yidong Wu; Tong Li; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5332.

Cornea December 2023

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

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Jing Feng; Lingling Yang; Lili Ran; Xia Qi; Xiaolei Wang; Yangyang Zhang; Zongzheng Zou; Ting Liu; Xiaochuan Wang; Yang Yu; Xiaodong Sun; Qingjun Zhou
TAGS: cornea, human herpesvirus 1, infections, keratitis, herpetic, macrophage-1 antigen, mice, symptom aggravating factors, viral load result
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):24. https://doi.org/10.1167/iovs.64.15.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Efficacy, durability, and safety of faricimab in diabetic macular edema (DME): 1-year results from China subpopulation of phase 3 RHINE trial

Xiaodong Sun; Xiaorong Li; Mei Han; Oluwatobi Idowu; Qin Jiang; Chi-Chun Lai; Ruyuan Liu; Wenxin Liu; Xiaoling Liu; Yannan Tang; Yanling Wang; Jeffrey Willis; Zhifeng Wu; Jian Ye; Li Zhang; Aachal Kotecha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2700.

Articles May 2022

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

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Ke Shi; Xinxin Li; Jingfa Zhang; Xiaodong Sun
TAGS: genes, intraocular melanoma, metabolism, patient prognosis
Trans. Vis. Sci. Tech.. 2022; 11(5):9. https://doi.org/10.1167/tvst.11.5.9

Includes: Supplemental Content

Articles January 2022

Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice

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Yuhong Chen; Xinyue Zhu; Fuxiang Ye; Hong Wang; Xiaoling Wan; Ting Zhang; Yuwei Wang; Yimin Wang; Xiaohuan Zhao; Xinyue Bai; Yushu Xiao; Xiaodong Sun
TAGS: choroidal neovascularization, malondialdehyde, mice, photoreceptors, retinal pigment cell, cell culture techniques, vascular endothelial growth factor a, injections
Trans. Vis. Sci. Tech.. 2022; 11(1):12. https://doi.org/10.1167/tvst.11.1.12

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2021

Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography

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Mengxi Shen; Hao Zhou; Kiyoung Kim; Qiyu Bo; Jie Lu; Rita Laiginhas; Xiaoshuang Jiang; Quan Yan; Prashanth Iyer; Omer Trivizki; Yingying Shi; Luis de Sisternes; Mary K. Durbin; William Feuer; Giovanni Gregori; Ruikang K. Wang; Xiaodong Sun; Fenghua Wang; Seung-Young Yu; Philip J. Rosenfeld
TAGS: angiogram, anti-vascular endothelial growth factor therapy, cortical blindness, eye, polypoidal choroidal vasculopathy, volume
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):5. https://doi.org/10.1167/iovs.62.15.5

Articles June 2021

Modeling Cone/Cone–Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina

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Yuwei Wang; Xiaomeng Li; Yang Yu; Jian Liang; Yang Liu; Yuhong Chen; Xinyue Bai; Jieqiong Chen; Fenghua Wang; Xueting Luo; Xiaodong Sun
TAGS: carrying, mice, mutation, pathology, photoreceptors, protein overexpression, proteins, retina, retinal cone, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2021; 10(7):25. https://doi.org/10.1167/tvst.10.7.25

Articles October 2020

Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

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Dongyan Pan; Mengqiao Xu; Xin Chang; Mao Xia; Yibin Fang; Yinghua Fu; Wei Shen; Yue Wang; Xiaodong Sun
TAGS: lasers, microdissection, optic nerve, rna, rna, messenger, retinal ganglion cells, genes, sequence analysis, rna
Trans. Vis. Sci. Tech.. 2020; 9(11):30. https://doi.org/10.1167/tvst.9.11.30

Includes: Supplemental Content

Retina July 2020

Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment

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Xiaomeng Li; Yang Liu; Mengsha Sun; Min Gao; Tong Li; Jian Liang; Yuanqi Zhai; Mengqiao Xu; Xiangjun She; Shiqi Yang; Wenjia Liu; Xueting Luo; Xiaodong Sun
TAGS: photoreceptors, pyroptosis, retina, retinal detachment, surgical procedures, operative, rats, western blotting
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):31. https://doi.org/10.1167/iovs.61.8.31

ARVO Annual Meeting Abstract June 2020

Hypo-reflective signals on en face structure imaging of spectral domain OCT angiography improved polypoidal lesion detection.

Xiaodong Sun; Fenghua Wang; Qiyu Bo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4817.

ARVO Annual Meeting Abstract June 2020

The proteomic profiles in aqueous humor of patients with neovascular age-related macular degeneration.

Tong Li; Jingfa Zhang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5007.

ARVO Annual Meeting Abstract June 2020

Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography

Li Su; Yongsok Ji; Nianting Tong; David Sarraf; Xiangui He; Xiaodong Sun; Xun Xu; Srinivas Sadda

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4807.

ARVO Annual Meeting Abstract June 2020

Evolution of Polypoidal Lesions after Anti-VEGF Treatment Using Swept-Source Optical Coherence Tomography Angiography in Polypoidal Choroidal Vasculopathy

Mengxi Shen; Qiyu Bo; Minlu Song; Giovanni Gregori; Xiaodong Sun; Fenghua Wang; Philip J Rosenfeld

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4816.

Articles February 2020

VEGFR1-Targeted Contrast-Enhanced Ultrasound Imaging Quantification of Vasculogenic Mimicry Microcirculation in a Mouse Model of Choroidal Melanoma

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Haiyun Liu; Min Gao; Jiying Gu; Xiaoling Wan; Hong Wang; Qing Gu; Yifan Zhou; Xiaodong Sun
TAGS: diagnostic imaging, malignant melanoma of choroid, melanoma, neoplasms, mice, contrast-enhanced ultrasonography, microcirculation, modified barium swallow, eye melanomas
Trans. Vis. Sci. Tech.. 2020; 9(3):4. https://doi.org/10.1167/tvst.9.3.4

Biochemistry and Molecular Biology November 2019

Chitinase-3-Like-1 Promotes M2 Macrophage Differentiation and Induces Choroidal Neovascularization in Neovascular Age-Related Macular Degeneration

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Nana Xu; Qiyu Bo; Rong Shao; Jian Liang; Yuanqi Zhai; Shiqi Yang; Fenghua Wang; Xiaodong Sun
TAGS: chitinase-3-like protein 1, choroidal neovascularization, macrophages, angiogenesis, exudative age-related macular degeneration, chitinases
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4596-4605. https://doi.org/10.1167/iovs.19-27493

Includes: Supplemental Content

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Preoperative OCT-Derived Nasal Perifoveal Retinal Nerve Fiber Layer Thickness Predictively Correlates Long-Term Visual Acuity Post Oil Removal Surgery

Clinical and Molecular Characterization of AIPL1 -Associated Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Comparable efficacy with aflibercept 8 mg at extended dosing intervals beyond q16 versus 2 mg q8 in Asian patients with nAMD in PULSAR through Week 96

Choroidal vascularity index (CVI) changes associated with lesion activity of polypoidal choroidal vasculopathy (PCV)

Gene therapy restores vision and delays degeneration in the CNGA1 -/- mouse model of retinitis pigmentosa

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b + Ly6G + Cells and Increasing the Viral Load in the Cornea

Efficacy, durability, and safety of faricimab in diabetic macular edema (DME): 1-year results from China subpopulation of phase 3 RHINE trial

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice

Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography

Modeling Cone/Cone–Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina

Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment

Hypo-reflective signals on en face structure imaging of spectral domain OCT angiography improved polypoidal lesion detection.

The proteomic profiles in aqueous humor of patients with neovascular age-related macular degeneration.

Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography

Evolution of Polypoidal Lesions after Anti-VEGF Treatment Using Swept-Source Optical Coherence Tomography Angiography in Polypoidal Choroidal Vasculopathy

VEGFR1-Targeted Contrast-Enhanced Ultrasound Imaging Quantification of Vasculogenic Mimicry Microcirculation in a Mouse Model of Choroidal Melanoma

Chitinase-3-Like-1 Promotes M2 Macrophage Differentiation and Induces Choroidal Neovascularization in Neovascular Age-Related Macular Degeneration

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