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ARVO Annual Meeting Abstract June 2025

Visual and Anatomic Outcomes of Vitrectomy for Myopic Maculoschisis with and without Macular Detachment: A Case-Control Study

Jun Li; Chonglin Chen; Sufen Lu; Xiaoyan Ding; Chun Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2842.

Retinal Cell Biology March 2025

Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling

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Xiaodi Zhou; Xiaoxiao Xu; Qiong Wang; Yanting Lai; Linyan Zhang; Yunfeng Lin; Xiaoyan Ding; Limei Sun
TAGS: endothelial cells, hypoxia, notch1 gene, retinal neovascularization, rna, small interfering, signal transduction, proteins, neovascularization, pathologic, ischemia, fluorescence
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):39. https://doi.org/10.1167/iovs.66.3.39

Retina February 2025

Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

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Xiaoyan Ding; Xiaodi Zhou; Xinyu Liu; Yanting Lai; Wenjia Yan; Yizhe Cheng; Aohan Hou; Limei Chen; Limei Sun
TAGS: angiogenesis, hypoxia, mice, neovascularization, pathologic, 1-phosphatidylinositol 3-kinase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):40. https://doi.org/10.1167/iovs.66.2.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Speed-Spatial Frequency-Contrast test, a novel vision test to predict the outcome of optic canal decompression for indirect traumatic optic neuropathy patients with pre-operative no light perception

Yang Gao; Ruifeng Liu; Jinmiao Li; Xinyue Wang; Yi Ren; Yujun Ma; Junjie Tang; Yanjie Xie; Xiaofeng Lin; Xiaoyan Ding; Shicai Su; Sheng Liu; Rong Lu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2450.

Retina March 2024

Genotype-Phenotype of CRB1-Associated Early-Onset Retinal Dystrophy: Novel Insights on Retinal Architecture and Therapeutic Window for Clinical Trials

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Yili Jin; Songshan Li; Zhaoxin Jiang; Limei Sun; Li Huang; Ting Zhang; Xinyu Liu; Xiaoyan Ding
TAGS: genotype, phenotype, retinal dystrophies, therapeutic index, child, genetics, signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):11. https://doi.org/10.1167/iovs.65.3.11

Retina May 2023

Identification of Five Novel Variants in the TSPAN12 Gene in Chinese Families With Familial Exudative Vitreoretinopathy

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You Wang; Qiong Wang; Songshan Li; Xiaoyan Ding
TAGS: chinese (other dialects), chinese people, familial exudative vitreoretinopathies, family, genes, luciferases
Trans. Vis. Sci. Tech.. 2023; 12(5):29. https://doi.org/10.1167/tvst.12.5.29

Artificial Intelligence April 2023

Deep Learning for Diagnosing and Segmenting Choroidal Neovascularization in OCT Angiography in a Large Real-World Data Set

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Jie Wang; Tristan T. Hormel; Kotaro Tsuboi; Xiaogang Wang; Xiaoyan Ding; Xiaoyan Peng; David Huang; Steven T. Bailey; Yali Jia
TAGS: choroidal neovascularization, datasets, angiogram, tissue membrane, deep learning
Trans. Vis. Sci. Tech.. 2023; 12(4):15. https://doi.org/10.1167/tvst.12.4.15

Biochemistry and Molecular Biology March 2023

Single-Cell Characterization of the Frizzled 5 ( Fz5 ) Mutant Mouse and Human Persistent Fetal Vasculature (PFV)

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Yuanyuan Chen; Cheng Wu; Shanzhen Peng; Dianlei Guo; Hong Ouyang; Yanhong Wei; Rong Ju; Xiaoyan Ding; Zhi Xie; Chunqiao Liu
TAGS: mice, persistent hyperplastic primary vitreous, vitreous body, melanocytes
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):8. https://doi.org/10.1167/iovs.64.3.8

Includes: Supplemental Content

Retina February 2023

Familial Exudative Vitreoretinopathy and Systemic Abnormalities in Patients With CTNNB1 Mutations

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Li Huang; Jinglin Lu; You Wang; Limei Sun; Xiaoyan Ding
TAGS: beta catenin, familial exudative vitreoretinopathies, mutation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):18. https://doi.org/10.1167/iovs.64.2.18

Retina April 2022

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

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Jinglin Lu; Li Huang; Limei Sun; Songshan Li; Zhaotian Zhang; Zhaoxin Jiang; Jiaqing Li; Xiaoyan Ding
TAGS: chinese (other dialects), familial exudative vitreoretinopathies, mutation, proband, signs and symptoms, phenotype, chinese people, family
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):7. https://doi.org/10.1167/iovs.63.4.7

Articles November 2021

Mydriasis-Free Flicker Electroretinograms in 204 Healthy Children Aged 0–18 Years: Reference Data From Two Cohorts

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Ting Zhang; Jinglin Lu; Limei Sun; Songshan Li; Li Huang; You Wang; Zeyu Li; Liming Cao; Xiaoyan Ding
TAGS: cohort studies, electroretinography, photopsia, well child, mydriasis
Trans. Vis. Sci. Tech.. 2021; 10(13):7. https://doi.org/10.1167/tvst.10.13.7

ARVO Imaging in the Eye Conference Abstract August 2021

Polyp Detection from Structural and Angiographic OCT Using Deep Learning

Tristan Hormel; Nida Wongchaisuwat; Nopasak Phasukkijwatana; Xiaoyan Ding; Steven T. Bailey; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2021; 62(11):82.

Articles July 2021

Diagnosis of Ocular Toxocariasis by Serum and Aqueous Humor IgG ELISA

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Li Huang; Limei Sun; Chengxi Liu; Songshan Li; Ting Zhang; Xiaoling Luo; Xiaoyan Ding
TAGS: immunoglobulin g, toxocara, ocular larva migrans, enzyme-linked immunosorbent assay, aqueous humor
Trans. Vis. Sci. Tech.. 2021; 10(8):33. https://doi.org/10.1167/tvst.10.8.33

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Diagnosing and segmenting choroidal neovascularization in optical coherence tomographic angiography using deep learning

JIE WANG; Tristan T. Hormel; kotaro tsuboi; Xiaogang Wang; Xiaoyan Ding; Xiaoyan Peng; Steven T Bailey; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2159.

Retina June 2019

Next-Generation Sequencing in the Familial Exudative Vitreoretinopathy-Associated Rhegmatogenous Retinal Detachment

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Chonglin Chen; Zhirong Wang; Limei Sun; Sijian Huang; Songshan Li; Aiyuan Zhang; Xiaoling Luo; Li Huang; Xiaoyan Ding
TAGS: familial exudative vitreoretinopathies, mutation, radiation recall dermatitis, rhegmatogenous retinal detachment, massively-parallel genome sequencing, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2659-2666. https://doi.org/10.1167/iovs.19-26619

Retina December 2018

Optical Coherence Tomography Angiography in Familial Exudative Vitreoretinopathy: Clinical Features and Phenotype-Genotype Correlation

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Chonglin Chen; Chengxi Liu; Zhirong Wang; Limei Sun; Xiujuan Zhao; Songshan Li; Xiaoling Luo; Aiyuan Zhang; Victor Chong; Lin Lu; Xiaoyan Ding
TAGS: familial exudative vitreoretinopathies, phenotype, angiogram, genotype, signs and symptoms, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5726-5734. https://doi.org/10.1167/iovs.18-25377

Lens July 2018

Wnt5a Contributes to the Differentiation of Human Embryonic Stem Cells into Lentoid Bodies Through the Noncanonical Wnt/JNK Signaling Pathway

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Chenlu Han; Jinyan Li; Chunxiao Wang; Hong Ouyang; Xiaoyan Ding; Yizhi Liu; Shuyi Chen; Lixia Luo
TAGS: wnt-5a protein, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3449-3460. https://doi.org/10.1167/iovs.18-23902

Includes: Supplemental Content

Retina November 2017

Mutation Spectrum of the LRP5 , NDP , and TSPAN12 Genes in Chinese Patients With Familial Exudative Vitreoretinopathy

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Miao Tang; Limei Sun; Andina Hu; Miner Yuan; Yu Yang; Xuening Peng; Xiaoyan Ding
TAGS: familial exudative vitreoretinopathies, mutation, genes, chinese (other dialects), chinese people
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5949-5957. https://doi.org/10.1167/iovs.17-22577

Includes: Supplemental Content

Retina January 2015

Posterior Pole Retinal Abnormalities in Mild Asymptomatic FEVR

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Miner Yuan; Yu Yang; Shanshan Yu; Andina Hu; Lin Lu; Jin Ma; Xiaoyan Ding; Jiaqing Li
TAGS: familial exudative vitreoretinopathies
Invest. Ophthalmol. Vis. Sci.. 2015; 56(1):458-463. https://doi.org/10.1167/iovs.14-15821

Glaucoma June 2013

Levels of Erythropoietin and Vascular Endothelial Growth Factor in Surgery-Required Advanced Neovascular Glaucoma Eyes Before and After Intravitreal Injection of Bevacizumab

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Minwen Zhou; Shida Chen; Wei Wang; Wenbin Huang; Bing Cheng; Xiaoyan Ding; Xiulan Zhang
TAGS: aqueous humor, vascular endothelial growth factor a, eye, bevacizumab, erythropoietin, glaucoma, neovascular, surgical procedures, operative, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):3874-3879. https://doi.org/10.1167/iovs.12-11507

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Visual and Anatomic Outcomes of Vitrectomy for Myopic Maculoschisis with and without Macular Detachment: A Case-Control Study

Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling

Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

Speed-Spatial Frequency-Contrast test, a novel vision test to predict the outcome of optic canal decompression for indirect traumatic optic neuropathy patients with pre-operative no light perception

Genotype-Phenotype of CRB1-Associated Early-Onset Retinal Dystrophy: Novel Insights on Retinal Architecture and Therapeutic Window for Clinical Trials

Identification of Five Novel Variants in the TSPAN12 Gene in Chinese Families With Familial Exudative Vitreoretinopathy

Deep Learning for Diagnosing and Segmenting Choroidal Neovascularization in OCT Angiography in a Large Real-World Data Set

Single-Cell Characterization of the Frizzled 5 ( Fz5 ) Mutant Mouse and Human Persistent Fetal Vasculature (PFV)

Familial Exudative Vitreoretinopathy and Systemic Abnormalities in Patients With CTNNB1 Mutations

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

Mydriasis-Free Flicker Electroretinograms in 204 Healthy Children Aged 0–18 Years: Reference Data From Two Cohorts

Polyp Detection from Structural and Angiographic OCT Using Deep Learning

Diagnosis of Ocular Toxocariasis by Serum and Aqueous Humor IgG ELISA

Diagnosing and segmenting choroidal neovascularization in optical coherence tomographic angiography using deep learning

Next-Generation Sequencing in the Familial Exudative Vitreoretinopathy-Associated Rhegmatogenous Retinal Detachment

Optical Coherence Tomography Angiography in Familial Exudative Vitreoretinopathy: Clinical Features and Phenotype-Genotype Correlation

Wnt5a Contributes to the Differentiation of Human Embryonic Stem Cells into Lentoid Bodies Through the Noncanonical Wnt/JNK Signaling Pathway

Mutation Spectrum of the LRP5 , NDP , and TSPAN12 Genes in Chinese Patients With Familial Exudative Vitreoretinopathy

Posterior Pole Retinal Abnormalities in Mild Asymptomatic FEVR

Levels of Erythropoietin and Vascular Endothelial Growth Factor in Surgery-Required Advanced Neovascular Glaucoma Eyes Before and After Intravitreal Injection of Bevacizumab

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