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ARVO Annual Meeting Abstract June 2024

A novel function of optineurin in axonal mitochondria transport for axon integrity and regeneration

Yang Hu; Dong Liu; Hannah Webber; Fuyun Bian; Manjari Prakash; Liang Li; In Jee You; Xue Feng; Hang Yang; Liping Liu; Pingting Liu; Ming Yang; Haoliang Huang; Zdenek Lansky

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):944.

ARVO Annual Meeting Abstract June 2024

High-throughput Screening of ATF4/CHOP inhibitors as Neuroprotectants for Glaucoma

Dong Liu; Wei Chen; Hang Yang; Liang Liu; Steve Schow; Robert Lum; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):674.

ARVO Annual Meeting Abstract June 2024

Longitudinal Dynamic Changes of RGC Axon Bundles in Mouse Silicone Oil-Induced Ocular Hypertension Glaucoma Model Revealed by Visible-light OCT Fibergraphy

Mingshen Ma; Weijia Fan; Liang Li; Hao F Zhang; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2520.

ARVO Annual Meeting Abstract June 2024

Anti-lipid peroxidation promotes significant optic nerve regeneration and neuroprotection in mouse glaucoma models

Ming Yang; Liang Li; Xue Feng; Haoliang Huang; Liang Liu; Dong Liu; Fuyun Bian; Roopa Dalal; Hang Yang; Frank Cao; Petrina Ong; Alexandria Luo; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3255.

ARVO Annual Meeting Abstract June 2024

Diseased RGC-specific targeting with gene therapy

Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5598.

ARVO Annual Meeting Abstract June 2024

Nme2Cas9-mediated Pten knockdown in RGCs promotes potent optic nerve regeneration after crush injury

Fuyun Bian; Xue Feng; Liang Li; Liang Liu; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6065.

ARVO Annual Meeting Abstract June 2024

Transmembrane protein CMTM6 inhibits Th17 cell differentiation and autoimmune inflammation in experimental dry eye

Yifan Zhou; huo yangbo; Baikai Ma; Wenling Han; Hong Qi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5722.

ARVO Annual Meeting Abstract June 2024

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

Linyu Shi; Weiwei Wu; Qi Yang; Sheng He; Mengke Zhu; Chenhua Yang; Shaoran Wang; Xing Wang; Xuan Yao; Alvin Luk; Hui Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6517.

ARVO Annual Meeting Abstract June 2024

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Weiwei Wu; Sheng He; Qi Yang; Chenhua Yang; Mengke Zhu; Shaoran Wang; Xuan Yao; Hui Yang; Alvin Luk; Linyu Shi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5091.

ARVO Annual Meeting Abstract June 2024

Complement Factor D Expression in Normal and Age-Related Macular Degeneration Human Eyes

Aixu Sun; Hua Yang; Ying Hu; Jingtai Cao; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):559.

ARVO Annual Meeting Abstract June 2024

Differential Analysis of Complement Expression and Localization Between Mouse, Rat, and Human Eyes

Aarin D Jones; Hua Yang; Aixu Sun; Guillermo Lehmann; Wen Fury; Ying Hu; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):558.

ARVO Annual Meeting Abstract June 2024

Empowering universal self-screening for malignant ocular rare tumors using smartphones

Ruixin Wang; Duoru Lin; Shaowei Bi; Mingyuan Li; Huasheng Yang; Haotian Lin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1604.

ARVO Annual Meeting Abstract June 2024

Progranulin-Deficient Mouse: A Valuable Model for GRN-related Eye Disorders

Hua Yang; ming yuan; Rajeev Wudali; Adrianna Latuszek; Henry Chen; Jacob Treinish; Ying Hu; Susan D. Croll; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4754.

ARVO Annual Meeting Abstract June 2024

World's First CRISPR/RNA-Targeting Therapy (HG202) for Patients with Neovascular Age-Related Macular Degeneration

Alvin Luk; Dongjun Xing; Boshi Liu; Weiwei Liu; Shuaishuai Zhang; Yuhan Jiang; Xuan Yao; Linyu Shi; Hui Yang; Yiqun Yuan; Xiaorong Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4357.

ARVO Annual Meeting Abstract June 2024

Ocular phenotypes in a mouse model of Pompe disease

Ming Yuan; Hua Yang; Ying Hu; Rajeev Wudali; Jingtai Cao; Andrew Baik; Farshid Sepehrband; Maria Praggastis; Katherine Cygnar; Andreja Avbersek; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5822.

Cornea May 2024

Corneal Endothelial Morphology and Ocular Biometric Indexes in Premature Children With and Without Retinopathy of Prematurity

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Hung-Chi Chen; Shun-Fa Yang; Chia-Yi Lee; Jing-Yang Huang; Yi-Jen Hsueh; Ming-Hui Sun; Ming-Chou Chiang; Yu-Shu Huang; Shih-Ming Chu; Jen-Fu Hsu; Chun-Hsiu Liu; Chao-Kai Chang; Kuan-Jen Chen; Yih-Shiou Hwang; Chi-Chun Lai; Chung-Ying Huang; Wei-Chi Wu
TAGS: biometry, child, cornea, endothelium, language morphology, morphology, retinopathy of prematurity, trend
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):37. https://doi.org/10.1167/iovs.65.5.37

Immunology and Microbiology February 2024

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

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Min Zhou; Bingying Lin; Pengsen Wu; Yu Ke; Siyu Huang; Fan Zhang; Xiangqing Hei; Zhen Mao; Xingyi Li; Pengxia Wan; Tingting Chen; Huasheng Yang; Danping Huang
TAGS: fibroblasts, graves' ophthalmopathy, mitogen-activated protein kinases, sox9 gene, fibrosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):25. https://doi.org/10.1167/iovs.65.2.25

Includes: Supplemental Content

Cornea January 2024

Transmembrane Protein CMTM6 Alleviates Ocular Inflammatory Response and Improves Corneal Epithelial Barrier Function in Experimental Dry Eye

PDF

Yifan Zhou; Baikai Ma; Qiyao Liu; Hongyu Duan; Yangbo Huo; Lu Zhao; Jiawei Chen; Wenling Han; Hong Qi
TAGS: cornea, dry eye syndromes, epithelium, inflammation, inflammatory response, integral membrane proteins, mice, stress, western blotting, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):4. https://doi.org/10.1167/iovs.65.1.4

Includes: Supplemental Content

Lens December 2023

HO-1–Mediated Autophagic Restoration Protects Lens Epithelial Cells Against Oxidative Stress and Cellular Senescence

PDF

Lijun Wang; Wei Lou; Yao Zhang; Ziang Chen; Yang Huang; Haiying Jin
TAGS: autophagy, cellular senescence, hydrogen peroxide, lens epithelial cell, lens, crystalline, oxidative stress, aging, older adult, mice, cyclophosphamide/prednisone/procarbazine/vincristine
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):6. https://doi.org/10.1167/iovs.64.15.6

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract August 2023

Reconstructing visual experience from a large-scale biologically realistic model of mouse primary visual cortex

Reza Abbasi-Asl; Yizhou Chi; Huibo Yang; Kael Dai; Anton Arkhipov

Journal of Vision. 2023; 23(9):5887. https://doi.org/10.1167/jov.23.9.5887

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A novel function of optineurin in axonal mitochondria transport for axon integrity and regeneration

High-throughput Screening of ATF4/CHOP inhibitors as Neuroprotectants for Glaucoma

Longitudinal Dynamic Changes of RGC Axon Bundles in Mouse Silicone Oil-Induced Ocular Hypertension Glaucoma Model Revealed by Visible-light OCT Fibergraphy

Anti-lipid peroxidation promotes significant optic nerve regeneration and neuroprotection in mouse glaucoma models

Diseased RGC-specific targeting with gene therapy

Nme2Cas9-mediated Pten knockdown in RGCs promotes potent optic nerve regeneration after crush injury

Transmembrane protein CMTM6 inhibits Th17 cell differentiation and autoimmune inflammation in experimental dry eye

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Complement Factor D Expression in Normal and Age-Related Macular Degeneration Human Eyes

Differential Analysis of Complement Expression and Localization Between Mouse, Rat, and Human Eyes

Empowering universal self-screening for malignant ocular rare tumors using smartphones

Progranulin-Deficient Mouse: A Valuable Model for GRN-related Eye Disorders

World's First CRISPR/RNA-Targeting Therapy (HG202) for Patients with Neovascular Age-Related Macular Degeneration

Ocular phenotypes in a mouse model of Pompe disease

Corneal Endothelial Morphology and Ocular Biometric Indexes in Premature Children With and Without Retinopathy of Prematurity

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

Transmembrane Protein CMTM6 Alleviates Ocular Inflammatory Response and Improves Corneal Epithelial Barrier Function in Experimental Dry Eye

HO-1–Mediated Autophagic Restoration Protects Lens Epithelial Cells Against Oxidative Stress and Cellular Senescence

Reconstructing visual experience from a large-scale biologically realistic model of mouse primary visual cortex

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