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Retina February 2025

Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

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Xiaoyan Ding; Xiaodi Zhou; Xinyu Liu; Yanting Lai; Wenjia Yan; Yizhe Cheng; Aohan Hou; Limei Chen; Limei Sun
TAGS: angiogenesis, hypoxia, mice, neovascularization, pathologic, 1-phosphatidylinositol 3-kinase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):40. https://doi.org/10.1167/iovs.66.2.40

Includes: Supplemental Content

Retina February 2025

Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment

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Yijing Chen; Xiaoya Zhang; Yanli Zhang; Shian Zhang; Yu Huo; Yubo Wu; Lijun Shen; Jianbo Mao
TAGS: anti-vascular endothelial growth factor therapy, aqueous humor, exudative age-related macular degeneration, metabolites, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):37. https://doi.org/10.1167/iovs.66.2.37

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

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Ying-Yi Chen; Chung-May Yang; Chang-Hao Yang; Tzyy-Chang Ho; Yi-Ting Hsieh; Tso-Ting Lai; Tzu-Hsun Tsai; Shu-Yi Huang
TAGS: ceramides, vitreous body, diabetic retinopathy, proliferative diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):28. https://doi.org/10.1167/iovs.66.2.28

Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics October 2024

Factors Affecting Stimulus Duration Threshold for Depth Discrimination of Asynchronous Targets in the Intermediate Distance Range

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Yiya Chen; Zijiang J. He; Teng Leng Ooi
TAGS: vision disparity, visual system, health disparity
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):36. https://doi.org/10.1167/iovs.65.12.36

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Age-related differences in detecting facial emotion changes: unveiling the impact of dynamic stimuli on sensitivity

Su-Ling Yeh; Po-Cheng Huang; Yu-Shan Chen; Yi-Chuan Chen

Journal of Vision. 2024; 24(10):356. https://doi.org/10.1167/jov.24.10.356

Vision Sciences Society Annual Meeting Abstract September 2024

Discriminating absolute depth of consecutively presented targets in the real environment with binocular disparity and relative height information

Yiya Chen; Zijiang He; Teng Leng Ooi

Journal of Vision. 2024; 24(10):749. https://doi.org/10.1167/jov.24.10.749

Vision Sciences Society Annual Meeting Abstract September 2024

Modularity of Brain Networks for Egocentric and Allocentric Memory-guided Reaching

Lina Musa; Amirhossein Ghaderi; Ying Chen; J. Douglas Crawford

Journal of Vision. 2024; 24(10):1298. https://doi.org/10.1167/jov.24.10.1298

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology August 2024

Binocular Visual Deficits at Low to High Spatial Frequency in Intermittent Exotropia After Surgery

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Xi Yu; Lili Wei; Yiya Chen; Hanyi Zhang; Huanyun Yu; Jiawei Zhou; Meiping Xu
TAGS: imbalance, intermittent exotropia, spatial frequency, surgical procedures, operative, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):41. https://doi.org/10.1167/iovs.65.10.41

Genetics August 2024

Gene‒Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study

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Shanshan Yin; Liyan Xu; Kaili Yang; Qi Fan; Yuwei Gu; Chenchen Yin; Yonghao Zang; Yifan Wang; Yi Yuan; Anqi Chang; Chenjiu Pang; Shengwei Ren
TAGS: chinese (other dialects), cohort studies, eye, genes, keratoconus, chinese people, gene-environment interaction
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):36. https://doi.org/10.1167/iovs.65.10.36

Glaucoma August 2024

Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

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Chia-Chen Hsu; Fang-Pai Lin; Hao-Chen Tseng; Pin Kuan Ho; Yi-Hsun Chen; Yann-Guang Chen; Da-Wen Lu; Yi-Hao Chen; Jian-Liang Chou; Hsin-Chih Chen; Yu Chuan Huang
TAGS: intraocular pressure, microspheres, myosin light chain kinase, ocular hypertension, open-angle glaucoma, oryctolagus cuniculus, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):17. https://doi.org/10.1167/iovs.65.10.17

Includes: Supplemental Content

Lens August 2024

Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells

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Jinyan Li; Jingyu Ma; Yijia Chen; Shuyi Chen; Lixia Luo; Hao Cheng
TAGS: epithelium, laminin, lens cell, lens, crystalline, pax6 transcription factor, crystallins, lens (device), genes, protein isoforms
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):12. https://doi.org/10.1167/iovs.65.10.12

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Assessing the Hydration Effects of Zwitterionic poly(carboxybetaine methacrylate) (polyCBMA) Hydrogels on Ocular Surface in Various Dry Eye Animal Models

Yi-Chen Sun; Jui-Tse Hung; Kai-Feng Hung

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5772.

ARVO Annual Meeting Abstract June 2024

Effect of Substance P in generation and maintenance of memory Th17 cells in dry eye

Shudan Wang; Amirreza Naderi; Francesca Kahale; Katayoon Forouzanfar; Yihe Chen; Reza Dana

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5738.

ARVO Annual Meeting Abstract June 2024

Disparities in glaucoma and macular degeneration healthcare utilization among persons living with dementia

Angela Chang; Ali G Hamedani; Yineng Chen; Brian L VanderBeek

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2810.

ARVO Annual Meeting Abstract June 2024

Sarcopenia as an etiology for blepharoptosis using orbital magnetic resonance imaging

Kendall Hughes; Jonathan Nguyen; Andres Rodriguez; Kamand Khalaj; Alice Z Chuang; Roy Riascos; Ying Chen; Timothy Mcculley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3046.

ARVO Annual Meeting Abstract June 2024

Bilamellar Tarsal Rotation (BLTR) vs Posterior Lamellar Tarsal Rotation (PLTR) for Trachomatous Trichiasis (TT)

John H Kempen; Yineng Chen; Aida Abashawl; Ahlam Awad Mohammed; Sarity Dodson; Wondu Alemayehu; Alemu Gemechu; Dereje Adugna; Aemero Abateneh; Tony Succar; Vatinee Y Bunya; Kathy McWilliams; Maureen G Maguire; Matthew Burton; Gui-Shuang Ying

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2813.

ARVO Annual Meeting Abstract June 2024

Enhancing Glaucoma Detection in African Ancestry Patients: A Comparative Analysis of Color Codes from the Cirrus HD-OCT Normative Database.

Chun Yin Chun-Yin Chow; Mina Halimitabrizi; Yineng Chen; Rebecca Salowe; Roy Lee; Lilian Chan; Naomi Gutkind; Qi N Cui; Victoria Addis; Gui-Shuang Ying; Joan M O'Brien

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2528.

ARVO Annual Meeting Abstract June 2024

Optic Disc Elschnig's Scleral Ring and Associated Factors among Glaucoma Patients: Primary Open-Angle African American Glaucoma Genetics (POAAGG) Study

Grace Kuang; Yineng Chen; Ebenezer Daniel; Rebecca Salowe; Gui-Shuang Ying; Victoria Addis; Prithvi Sankar; Joan M O'Brien

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2522.

ARVO Annual Meeting Abstract June 2024

New insight of residual Perfluorocarbon Liquid removal in vitreoretinal surgery

Ying Chen; Wang Yee Chu; Zhongdui Long; Yau Kei Chan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):907.

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Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach

Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

Factors Affecting Stimulus Duration Threshold for Depth Discrimination of Asynchronous Targets in the Intermediate Distance Range

Age-related differences in detecting facial emotion changes: unveiling the impact of dynamic stimuli on sensitivity

Discriminating absolute depth of consecutively presented targets in the real environment with binocular disparity and relative height information

Modularity of Brain Networks for Egocentric and Allocentric Memory-guided Reaching

Binocular Visual Deficits at Low to High Spatial Frequency in Intermittent Exotropia After Surgery

Gene‒Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study

Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells

Assessing the Hydration Effects of Zwitterionic poly(carboxybetaine methacrylate) (polyCBMA) Hydrogels on Ocular Surface in Various Dry Eye Animal Models

Effect of Substance P in generation and maintenance of memory Th17 cells in dry eye

Disparities in glaucoma and macular degeneration healthcare utilization among persons living with dementia

Sarcopenia as an etiology for blepharoptosis using orbital magnetic resonance imaging

Bilamellar Tarsal Rotation (BLTR) vs Posterior Lamellar Tarsal Rotation (PLTR) for Trachomatous Trichiasis (TT)

Enhancing Glaucoma Detection in African Ancestry Patients: A Comparative Analysis of Color Codes from the Cirrus HD-OCT Normative Database.

Optic Disc Elschnig's Scleral Ring and Associated Factors among Glaucoma Patients: Primary Open-Angle African American Glaucoma Genetics (POAAGG) Study

New insight of residual Perfluorocarbon Liquid removal in vitreoretinal surgery

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