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ARVO Annual Meeting Abstract June 2024

The role of Smad4 in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil Ghag; Winston Kao; Shizuya Saika; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):502.

ARVO Annual Meeting Abstract June 2024

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

chia-yang liu; Yong Yuan; Yen-Chiao Wang; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3647.

ARVO Annual Meeting Abstract June 2024

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

Yen-Chiao Wang; Yuan Yong; Olivia Zolnik; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):520.

Glaucoma December 2023

The Effects of ROCK Inhibitor on Prevention of Dexamethasone-Induced Glaucoma Phenotype in Human Trabecular Meshwork Cells

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Tilahun Ayane Debele; Zachary F. Mount; Yong Yuan; Winston W.-Y. Kao; Yoonjee C. Park
TAGS: actins, collagen, cytotoxicity, dexamethasone, gel, glaucoma, permeability, phenotype, prevention, trabecular meshwork
Trans. Vis. Sci. Tech.. 2023; 12(12):4. https://doi.org/10.1167/tvst.12.12.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Role of Lumican on TgfβR Signaling in The Healing of Deep Corneal Epithelial Debridement

Winston Kao; Jianhua Zhang; Shingo Yasuda; Yong Yuan; Shizuya Saika; chia-yang liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):506.

ARVO Annual Meeting Abstract June 2023

The role of TGFbR1 signal in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil; Winston Kao; Shizuya Saika; chia-yang liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3163.

ARVO Annual Meeting Abstract June 2023

Molecular analyses of corneal ectasia in Tgfb receptors signaling-deficiency mouse models

chia-yang liu; Shingo Yasuda; Yong Yuan; Yen-Chiao Wang; Shizuya Saika; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3141.

Cornea July 2020

Excess Transforming Growth Factor-α Changed the Cell Properties of Corneal Epithelium and Stroma

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Lingling Zhang; Yong Yuan; Lung-Kun Yeh; Fei Dong; Jianhua Zhang; Yuka Okada; Winston W.Y. Kao; Chia-Yang Liu; Yujin Zhang
TAGS: cornea, corneal epithelium, mice, phenotype, cells, keratocytes
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):20. https://doi.org/10.1167/iovs.61.8.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Characterization and Evaluation of Cell Therapy Efficacy in Novel Cystinotic Mouse Lines

Winston W Y Kao; Fei Dong; Hassane Amlal; Jianhua Zhang; Yong Yuan; Yueh-Chiang Hu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2747.

ARVO Annual Meeting Abstract July 2018

Role of TGF-β Receptor 1 (Tgfbr1/Alk5) on The Healing of Corneal Epithelium Debridement

Winston W Y Kao; Fei Dong; Jianhua Zhang; Yong Yuan; Yueh-Chiang HU

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4329.

Cornea September 2017

Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA ( Kera RT ), for Corneal Stroma and Tendon Research

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Yujin Zhang; Winston W.-Y. Kao; Yasuhito Hayashi; Lingling Zhang; Mindy Call; Fei Dong; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Okada Yuka; Atsushi Shiraishi; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4800-4808. https://doi.org/10.1167/iovs.17-22661

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Gene Therapy of Mucopolysaccharidosis Type VII (MPS VII) with CRISPR/Cas9 Genome Editing

Winston W Y Kao; Tarsis Ferreira; Yong Yuan; Fei Dong; Yueh-Chiang Hu; Mindy Call; Vivien Jane Coulson-Thomas; Jianhua Zhang; Taylor Rice

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3374.

ARVO Annual Meeting Abstract June 2015

Activation of Noncanonical Wnt Signaling Elicits Glaucoma in Mice

Yong Yuan; Liyun Zhang; Fei Dong; Yujin Zhang; Mindy Call; Chia-yang Liu; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3677.

ARVO Annual Meeting Abstract June 2015

CD44 regulates extracellular matrix assembly by umbilical cord mesenchymal stem cells enabling host rejection suppression.

Tarsis G Ferreira; Vivien J Coulson-Thomas; Yong Yuan; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5623.

ARVO Annual Meeting Abstract April 2014

Roles of Lumikine on the Healing of Corneal Epithelium Debridement in Vivo

Winston W Y Kao; Jianhua Zhang; Vivien Jane Coulson-Thomas; Mindy Kay Call; Yong Yuan; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4609.

ARVO Annual Meeting Abstract April 2014

Lum binds Alk5 to promote healing of corneal epithelium debridement in vivo

Jianhua Zhang; Vivien Jane Coulson-Thomas; Yong Yuan; Yujin Zhang; Chia-Yang Liu; Winston W Y Kao; None

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4686.

Glaucoma October 2013

Dexamethasone Induces Cross-Linked Actin Networks in Trabecular Meshwork Cells Through Noncanonical Wnt Signaling

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Yong Yuan; Mindy K. Call; Yan Yuan; Yujin Zhang; Katy Fischesser; Chia-Yang Liu; Winston W.-Y. Kao
TAGS: actins, dexamethasone, ligands, proteins, receptor tyrosine kinase-like orphan receptor 2, signal transduction, trabecular meshwork, polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6502-6509. https://doi.org/10.1167/iovs.13-12447

ARVO Annual Meeting Abstract June 2013

Lumican Is Required for Epithelium Migration during Healing of Corneal Epithelium Debridement

Jianhua Zhang; Vivien Coulson-Thomas; Yong Yuan; Osamu Yamanaka; Hongshan Liu; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2568.

ARVO Annual Meeting Abstract June 2013

Dexamethasone induces stress fiber re-arrangement through non-canonical Wnt signaling in trabecular meshwork cells

Yong Yuan; Chia-Yang Liu; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3532.

ARVO Annual Meeting Abstract June 2013

Umbilical mesenchymal stem cell transplantation for dry eye in the mouse model

Hongshan Liu; Yujin Zhang; Yong Yuan; Jianhua Zhang; Chia-yang Liu; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2192.

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The role of Smad4 in corneal development and homeostasis

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

The Effects of ROCK Inhibitor on Prevention of Dexamethasone-Induced Glaucoma Phenotype in Human Trabecular Meshwork Cells

Role of Lumican on TgfβR Signaling in The Healing of Deep Corneal Epithelial Debridement

The role of TGFbR1 signal in corneal development and homeostasis

Molecular analyses of corneal ectasia in Tgfb receptors signaling-deficiency mouse models

Excess Transforming Growth Factor-α Changed the Cell Properties of Corneal Epithelium and Stroma

Characterization and Evaluation of Cell Therapy Efficacy in Novel Cystinotic Mouse Lines

Role of TGF-β Receptor 1 (Tgfbr1/Alk5) on The Healing of Corneal Epithelium Debridement

Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA ( Kera RT ), for Corneal Stroma and Tendon Research

Gene Therapy of Mucopolysaccharidosis Type VII (MPS VII) with CRISPR/Cas9 Genome Editing

Activation of Noncanonical Wnt Signaling Elicits Glaucoma in Mice

CD44 regulates extracellular matrix assembly by umbilical cord mesenchymal stem cells enabling host rejection suppression.

Roles of Lumikine on the Healing of Corneal Epithelium Debridement in Vivo

Lum binds Alk5 to promote healing of corneal epithelium debridement in vivo

Dexamethasone Induces Cross-Linked Actin Networks in Trabecular Meshwork Cells Through Noncanonical Wnt Signaling

Lumican Is Required for Epithelium Migration during Healing of Corneal Epithelium Debridement

Dexamethasone induces stress fiber re-arrangement through non-canonical Wnt signaling in trabecular meshwork cells

Umbilical mesenchymal stem cell transplantation for dry eye in the mouse model

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