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ARVO Annual Meeting Abstract June 2024

Conjunctival transcriptome changes in Sjögren Syndrome and non-Sjögren Syndrome aqueous-tear-deficient dry eye

Cintia S De Paiva; Stephen C Pflugfelder; Zhiyuan Yu; Robert Britton; Laura Schaefer; Kaitlin Scholand

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):412.

ARVO Annual Meeting Abstract June 2024

Exploring the Transformative Effects of Calorie Restriction on the Lacrimal Gland

Olivier Mauduit; Kaitlin Scholand; Laura Schaefer; Vanessa DELCROIX; Zhiyuan Yu; Helen P Makarenkova; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6544.

Biochemistry and Molecular Biology May 2024

Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing

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Anmar Abu-Romman; Kaitlin K. Scholand; Gowthaman Govindarajan; Zhiyuan Yu; Sonali Pal-Ghosh; Mary A. Stepp; Cintia S. de Paiva
TAGS: cornea, debridement, epithelium, mice, wound healing, wounds and injuries, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):21. https://doi.org/10.1167/iovs.65.5.21

Includes: Supplemental Content

Anatomy and Pathology/Oncology August 2023

Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype

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Jeremias G. Galletti; Kaitlin K. Scholand; Claudia M. Trujillo-Vargas; Wolfgang Haap; Tiago Santos-Ferreira; Christoph Ullmer; Zhiyuan Yu; Cintia S. de Paiva
TAGS: aging, cathepsins, dry eye syndromes, mice, phenotype, diet
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):7. https://doi.org/10.1167/iovs.64.11.7

Includes: Supplemental Content

Cornea & External Disease June 2023

Differentially Expressed Tear Proteins in Sjögren's Syndrome Keratoconjunctivitis Sicca

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Stephen P. Yoon; Zhiyuan Yu; Stephen C. Pflugfelder; Cintia S. de Paiva
TAGS: proteins, sjogren's syndrome, keratoconjunctivitis sicca
Trans. Vis. Sci. Tech.. 2023; 12(6):8. https://doi.org/10.1167/tvst.12.6.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Corneal Epithelial Wound Healing in CD25KO Model of Sjögren Syndrome

Cintia S. De Paiva; Anmar Ali Abu-Romman; Kaitlin Scholand; Zhiyuan Yu; Mary Ann Stepp

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3131.

Immunology and Microbiology April 2023

Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model

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Zhiyuan Yu; Ghasem Yazdanpanah; Jehan Alam; Cintia S. de Paiva; Stephen Pflugfelder
TAGS: corneal epithelium, dry eye syndromes, nf-kappa b, stress, nlr family, pyrin domain-containing 3 protein, inflammasomes
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):8. https://doi.org/10.1167/iovs.64.4.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Differentially expressed tear proteins in Sjögren syndrome keratoconjunctivitis sicca

Stephen Paul Yoon; Eduardo Serrano; Zhiyuan Yu; Stephen C Pflugfelder; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1537 – A0262.

ARVO Annual Meeting Abstract June 2022

Evaluation of novel YP-P10 Peptide in animal models of inflammatory dry eye disease

Larry Chong Park; Laxmikant Gharat; Kyungho Park; Jahan Alam; Zhiyuan Yu; Yelin Hu; Cintia S De Paiva; Gary D Novack; Stephen C Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1984 – A0314.

ARVO Annual Meeting Abstract June 2022

Small molecule agonists of Tyrosine Kinase receptors improve dry eye disease

Zhiyuan Yu; Ghasem Yazdanpanah; Tye S Thompson; Kevin Burgess; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1979 – A0309.

ARVO Annual Meeting Abstract June 2022

Effects of Cathepsin S inhibition in the Aged Lacrimal Gland

Jeremias Gaston Galletti; Kaitlin Scholand; Wolfgang Haap; Tiago Ferreira; Zhiyuan Yu; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1974 – A0304.

ARVO Annual Meeting Abstract June 2022

Reduced RXRα signaling increases dry eye disease inducing γδT17 cells in the conjunctiva

Stephen C Pflugfelder; Jahan Alam; Ghasem Yazdanpanah; Rinki Ratnapriya; Nicholas Borcherding; Cintia S De Paiva; De-Quan Li; Rodrigo Guimaraes de Souza; Zhiyuan Yu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2276.

ARVO Annual Meeting Abstract June 2022

Effects of Age and Genetic Diversity Background on Ectopic Lymphoid Structures in the Lacrimal Gland

Cintia S De Paiva; Kaitlin Scholand; Helen P Makarenkova; Zhiyuan Yu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2275.

ARVO Annual Meeting Abstract June 2022

Evidence for IL-2 signaling in corneal epithelium

Sonali Pal Ghosh; Zhiyuan Yu; Yashaswini Kelegere; Ghasem Yazdanpanah; Gauri Tadvalkar; Winston Kao; Vivien Jane Coulson-Thomas; Mary Ann Stepp; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3246 – A0281.

ARVO Annual Meeting Abstract June 2021

Effects of age, TNF-α and calorie restriction on cathepsin S and other inflammatory markers in the lacrimal gland

Cintia S De Paiva; Erica N DeJong; Andrea Lee; Kelsey E. Mauk; Dawn ME Bowdish; Aude I. Sindikubwabo; Ron Korstanje; Zhiyuan Yu; Helen P Makarenkova

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2045.

ARVO Annual Meeting Abstract June 2021

Retinoid X receptor alpha (RXRa) mutant Pinkie and vitamin A deficient B6 mice develop similar spectrum of corneal inflammation

Jehan Alam; Zhiyuan Yu; Rinki Ratnapriya; Cintia S De Paiva; Stephen C Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):912.

ARVO Annual Meeting Abstract June 2021

Activation of NFkB and NLRP3 Inflammasome in the corneal epithelium following short-term desiccating stress

Zhiyuan Yu; Stephen C Pflugfelder; Jehan Alam; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1299.

ARVO Annual Meeting Abstract June 2020

Attenuated RXRa mediated suppression of innate IFN-γ production by conjunctival monocytes promotes conjunctiva goblet cell loss - implications for xerophthalmia of vitamin A deficiency

Jahan Alam; Stephen C Pflugfelder; Cintia De Paiva; Rodrigo de Souza; Zhiyuan Yu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):138.

ARVO Annual Meeting Abstract June 2020

Comparison of desiccating stress without or with inhibition of tear secretion on activation of the IL-12/STAT4 pathway

Zhiyuan Yu; Jahan Alam; Cintia De Paiva; Stephen Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):145.

ARVO Annual Meeting Abstract June 2020

TRANSCRIPTIONAL EXPRESSION OF IMMUNE GENES IN THE SJÖGREN SYNDROME CONJUNCTIVA

Claudia M. Trujillo-Vargas; Laura Schaefer; Zhiyuan Yu; Stephen Pflugfelder; Robert A. Britton; Cintia De Paiva

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1379.

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Conjunctival transcriptome changes in Sjögren Syndrome and non-Sjögren Syndrome aqueous-tear-deficient dry eye

Exploring the Transformative Effects of Calorie Restriction on the Lacrimal Gland

Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing

Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype

Differentially Expressed Tear Proteins in Sjögren's Syndrome Keratoconjunctivitis Sicca

Corneal Epithelial Wound Healing in CD25KO Model of Sjögren Syndrome

Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model

Differentially expressed tear proteins in Sjögren syndrome keratoconjunctivitis sicca

Evaluation of novel YP-P10 Peptide in animal models of inflammatory dry eye disease

Small molecule agonists of Tyrosine Kinase receptors improve dry eye disease

Effects of Cathepsin S inhibition in the Aged Lacrimal Gland

Reduced RXRα signaling increases dry eye disease inducing γδT17 cells in the conjunctiva

Effects of Age and Genetic Diversity Background on Ectopic Lymphoid Structures in the Lacrimal Gland

Evidence for IL-2 signaling in corneal epithelium

Effects of age, TNF-α and calorie restriction on cathepsin S and other inflammatory markers in the lacrimal gland

Retinoid X receptor alpha (RXRa) mutant Pinkie and vitamin A deficient B6 mice develop similar spectrum of corneal inflammation

Activation of NFkB and NLRP3 Inflammasome in the corneal epithelium following short-term desiccating stress

Attenuated RXRa mediated suppression of innate IFN-γ production by conjunctival monocytes promotes conjunctiva goblet cell loss - implications for xerophthalmia of vitamin A deficiency

Comparison of desiccating stress without or with inhibition of tear secretion on activation of the IL-12/STAT4 pathway

TRANSCRIPTIONAL EXPRESSION OF IMMUNE GENES IN THE SJÖGREN SYNDROME CONJUNCTIVA

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