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Special Issue December 2020

Identifying Mouse Autoimmune Uveitis from Fundus Photographs Using Deep Learning

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Jian Sun; Xiaoqin Huang; Charles Egwuagu; Youakim Badr; Stephen Charles Dryden; Brian Thomas Fowler; Siamak Yousefi

Trans. Vis. Sci. Tech.. 2020; 9(2):59. doi: https://doi.org/10.1167/tvst.9.2.59

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Loss of interferon regulatory factor 8 (IRF-8) in B cells promotes the expansion of regulatory B cells (Bregs) and suppresses intraocular autoimmune disease

Chengrong Yu; Hyunsu Lee; Daniel Gebreselasssie; Jin Kyeong Choi; Mary Mattapallil; Favour Oladipupop; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2544. doi:

ARVO Annual Meeting Abstract July 2018

Interferon Regulatory Factor 8 (IRF8) antagonizes IL-10 and CTLA4 production in T cells

Hyunsu Lee; Chengrong Yu; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2545. doi:

ARVO Annual Meeting Abstract July 2018

Therapeutic potential of IL-12p35 Subunit for treatment of uveitis and multiple sclerosis

Jin Kyeong Choi; Chengrong Yu; Anita Uche; Mary J Mattapallil; Favour Oladipupop; Minkyung Kang; Rachel R Caspi; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2550. doi:

ARVO Annual Meeting Abstract June 2017

IL-12p35 induces expansion of IL-10- and IL-35-expressing regulatory B cells (Bregs) and ameliorates autoimmune disease

Jin Kyeong Choi; Venkat Mohanram; Chengrong Yu; Anita Uche; Daniel Gebreselassie; Hyunsu lee; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):543. doi:

ARVO Annual Meeting Abstract June 2017

Human IL35-producing B cells (I35Bregs) are induced by CpG DNA

Chengrong Yu; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):559. doi:

ARVO Annual Meeting Abstract September 2016

IL-10- and IL-35-expressing cells are highly enriched among peripheral blood B cells during experimental autoimmune uveitis

Chengrong Yu; Rashid M Mahdi; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):495. doi:

ARVO Annual Meeting Abstract June 2015

Genetic engineering and characterization of recombinant mouse IL-27 cytokine

Justine Yeung; Lekha Nair; Lin Sun; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3489. doi:

ARVO Annual Meeting Abstract April 2014

Suppression of experimental autoimmune uveitis (EAU) and recovery from uveitis correlate with expansion of regulatory B cells (Breg)

Chengrong Yu; Ivy M Dambuza; Sung-Hye Kim; Rashid M Mahdi; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2493. doi:

ARVO Annual Meeting Abstract April 2014

Characterization of the Role of IRF-8 in the Retina During Autoimmune Uveitis

Sung-Hye Kim; Chengrong Yu; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2503. doi:

ARVO Annual Meeting Abstract June 2013

Osteopontin is Expressed by Microglia and T Cells and Regulated by STAT3

Chengrong Yu; Waynekid Kam; Ivy Dambuza; Bernadette Marrero; Rashid Mahdi; Charles E. Egwuagu; immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2050. doi:

ARVO Annual Meeting Abstract June 2013

IRF-8 Antagonizes Th17 and Tc17 Expansion and Restrains Th17 Inflammatory Responses During Autoimmune Uveitis

Sung-Hye Kim; Chengrong Yu; Bernadette Marrero; Charles E. Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2535. doi:

ARVO Annual Meeting Abstract June 2013

IL-12p35 Inhibits Th1 proliferation and promotes the expansion of Th17 and Treg

Ivy Dambuza; Chengrong Yu; Rashid Mahdi; Renxi Wang; Sung-Hye Kim; Charles E. Egwuagu; Immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):101. doi:

ARVO Annual Meeting Abstract June 2013

STAT3/SOCS3 axis modulates CD8-mediated host immunity against HSV-1

Fatemeh Navid; Chengrong Yu; Ivy Dambuza; Gregory M. Frank; Charles E. Egwuagu; Immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5989. doi:

Immunology and Microbiology June 2013

STAT3 Activates miR-155 in Th17 Cells and Acts in Concert to Promote Experimental Autoimmune Uveitis

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Thelma Escobar; Cheng-Rong Yu; Stefan A. Muljo; Charles E. Egwuagu
TAGS: autoimmune diseases, autoimmunity, mice, stat3 protein, th17 cells, t-lymphocytes, uveitis
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):4017-4025. doi: https://doi.org/10.1167/iovs.13-11937

ARVO Annual Meeting Abstract March 2012

Temporal Expression of miR-155 Correlates with the initiation and Development of Experimental Autoimmune Uveitis (EAU)

Bernadette Marrero; Yu Chen-Rong; Chandrasekharam Nagineni; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6238. doi:

ARVO Annual Meeting Abstract March 2012

Genetically Engineered IL-30 (IL27p28) Suppresses Experimental Autoimmune Uveitis

Ren-Xi Wang; Cheng-Yong Yu; Rashid Mahdi; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6282. doi:

ARVO Annual Meeting Abstract March 2012

Resveratrol: Potential Drug For Treating Uveitis And Other Autoimmune Disease

Sung-Hye Kim; Da-Young Ko; Jenna Burton; Cheng-Rong Yu; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2761. doi:

ARVO Annual Meeting Abstract March 2012

IL-27 regulates expression of Complement Factor H in the Retina

Ivy M. Dambuza; Ahjoku Amadi-Obi; Cheng-Rong Yu; Charles E. Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5274. doi:

Immunology and Microbiology August 2011

Suppressor of Cytokine Signaling-1 (SOCS1) Inhibits Lymphocyte Recruitment into the Retina and Protects SOCS1 Transgenic Rats and Mice from Ocular Inflammation

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Cheng-Rong Yu; Rashid R. Mahdi; Hyun-Mee Oh; Ahjoku Amadi-Obi; Grace Levy-Clarke; Jenna Burton; Amarachi Eseonu; YongJun Lee; Chi-Chao Chan; Charles E. Egwuagu
TAGS: animals, transgenic, cytokine, mice, rats, retina, socs1 gene, uveitis, eye inflammation, signal transduction, lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2011; 52(9):6978-6986. doi: https://doi.org/10.1167/iovs.11-7688

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Identifying Mouse Autoimmune Uveitis from Fundus Photographs Using Deep Learning

Loss of interferon regulatory factor 8 (IRF-8) in B cells promotes the expansion of regulatory B cells (Bregs) and suppresses intraocular autoimmune disease

Interferon Regulatory Factor 8 (IRF8) antagonizes IL-10 and CTLA4 production in T cells

Therapeutic potential of IL-12p35 Subunit for treatment of uveitis and multiple sclerosis

IL-12p35 induces expansion of IL-10- and IL-35-expressing regulatory B cells (Bregs) and ameliorates autoimmune disease

Human IL35-producing B cells (I35Bregs) are induced by CpG DNA

IL-10- and IL-35-expressing cells are highly enriched among peripheral blood B cells during experimental autoimmune uveitis

Genetic engineering and characterization of recombinant mouse IL-27 cytokine

Suppression of experimental autoimmune uveitis (EAU) and recovery from uveitis correlate with expansion of regulatory B cells (Breg)

Characterization of the Role of IRF-8 in the Retina During Autoimmune Uveitis

Osteopontin is Expressed by Microglia and T Cells and Regulated by STAT3

IRF-8 Antagonizes Th17 and Tc17 Expansion and Restrains Th17 Inflammatory Responses During Autoimmune Uveitis

IL-12p35 Inhibits Th1 proliferation and promotes the expansion of Th17 and Treg

STAT3/SOCS3 axis modulates CD8-mediated host immunity against HSV-1

STAT3 Activates miR-155 in Th17 Cells and Acts in Concert to Promote Experimental Autoimmune Uveitis

Temporal Expression of miR-155 Correlates with the initiation and Development of Experimental Autoimmune Uveitis (EAU)

Genetically Engineered IL-30 (IL27p28) Suppresses Experimental Autoimmune Uveitis

Resveratrol: Potential Drug For Treating Uveitis And Other Autoimmune Disease

IL-27 regulates expression of Complement Factor H in the Retina

Suppressor of Cytokine Signaling-1 (SOCS1) Inhibits Lymphocyte Recruitment into the Retina and Protects SOCS1 Transgenic Rats and Mice from Ocular Inflammation

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