Biochemistry and Molecular Biology

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Glaucoma January 2025

Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork

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Faycal Moujane; Chi Zhang; Robert Knight; John Y. Lee; Sophie X. Deng; Jie J. Zheng
TAGS: attenuation, cornea, extracellular vesicles, glaucoma, myoc gene, trabecular meshwork, culture media, conditioned, dexamethasone, genes, intraocular pressure
Trans. Vis. Sci. Tech.. 2025; 14(1):21. https://doi.org/10.1167/tvst.14.1.21

Letters to the Editor January 2025

An Alternative Mechanism for the Anti-Myopia Effectiveness of Diffusion Optics Technology (DOT) Lenses

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Timothy J. Gawne; Safal Khanal; Thomas T. Norton
TAGS: diffusion, lens (device), lens, crystalline, myopia, optics, technology
Trans. Vis. Sci. Tech.. 2025; 14(1):15. https://doi.org/10.1167/tvst.14.1.15

Retina January 2025

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

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Shizhen Lei; Yani Liu
TAGS: gastrointestinal microbiome, genetic correlation analysis, genetics, mendelian randomization analysis, retinal vein occlusion
Trans. Vis. Sci. Tech.. 2025; 14(1):5. https://doi.org/10.1167/tvst.14.1.5

Includes: Supplemental Content

Editorial December 2024

Reviewers

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TAGS: bsnd gene, gangs, happiness, laparoscopic uterosacral nerve ablation, reading (activity), tolnaftate, acetylcholine, achondroplasia, camurati-engelmann syndrome, e-selectin
Trans. Vis. Sci. Tech.. 2024; 13(12):38. https://doi.org/10.1167/tvst.13.12.38

Artificial Intelligence November 2024

Associations of Metabolically Healthy Obesity and Retinal Age Gap

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Xiaomin Zeng; Ruiye Chen; Gabriella Bulloch; Qingsheng Peng; Ching-Yu Cheng; Mingguang He; Honghua Yu; Zhuoting Zhu
TAGS: obesity, obesity, metabolically benign, phenotype, body mass index procedure, body weight
Trans. Vis. Sci. Tech.. 2024; 13(11):26. https://doi.org/10.1167/tvst.13.11.26

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Retina November 2024

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

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Huan Liu; Feiyan Wang; Ziqing Hu; Jing Wei
TAGS: diabetic retinopathy, drug delivery systems, mendelian randomization analysis, plasma proteins, proteins
Trans. Vis. Sci. Tech.. 2024; 13(11):17. https://doi.org/10.1167/tvst.13.11.17

Includes: Supplemental Content

Review October 2024

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

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Jay Neitz; Maureen Neitz
TAGS: lens (device), myopia, optics, lens, crystalline, eye, retina, diffusion, technology
Trans. Vis. Sci. Tech.. 2024; 13(10):42. https://doi.org/10.1167/tvst.13.10.42

Retina September 2024

Model Predictive Temperature Control for Retinal Laser Treatments

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Viktoria Kleyman; Sophie Eggert; Christian Schmidt; Manuel Schaller; Karl Worthmann; Ralf Brinkmann; Matthias A. Müller
TAGS: body temperature regulation, laser therapy, lasers, process of absorption, temperature, body temperature, eye
Trans. Vis. Sci. Tech.. 2024; 13(9):28. https://doi.org/10.1167/tvst.13.9.28

Cornea & External Disease September 2024

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

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Yuan Chang; Tianze Huang; Shan Yang; Ying Li; Di Chen
TAGS: atopic dermatitis, keratoconus, mendelian randomization analysis, genome-wide association study, datasets
Trans. Vis. Sci. Tech.. 2024; 13(9):13. https://doi.org/10.1167/tvst.13.9.13

Includes: Supplemental Content

Artificial Intelligence September 2024

Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method

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Najung Kim; Minsub Lee; Hyewon Chung; Hyung Chan Kim; Hyungwoo Lee
TAGS: age-related macular degeneration, anti-vascular endothelial growth factor therapy, cohort studies, diagnostic imaging, drug loading dose, injections, machine learning, visual acuity, treatment protocols, eye
Trans. Vis. Sci. Tech.. 2024; 13(9):3. https://doi.org/10.1167/tvst.13.9.3

Includes: Supplemental Content

Glaucoma August 2024

Comparison of SNCG and NEFH Promoter–Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma

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Nuala O'Neill; Miranda Meng; Brahim Chaqour; Kimberly Dine; Neha Sarabu; Jennifer C. Pham; Kenneth S. Shindler; Ahmara G. Ross
TAGS: glaucoma, mice, spatial vectors, enhancer of transcription, genes, cytomegalovirus
Trans. Vis. Sci. Tech.. 2024; 13(8):37. https://doi.org/10.1167/tvst.13.8.37

Retina August 2024

Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology

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Rami A. Shahror; Esraa Shosha; Marco H. Ji; Carol A. Morris; Melissa Wild; Bushra Zaman; Christian D. Mitchell; Pedro Tetelbom; Yuet-Kin Leung; Paul H. Phillips; Ahmed A. Sallam; Abdelrahman Y. Fouda
TAGS: aqueous humor, central retinal artery occlusion, hypertension, proteins, pathophysiology, clusterin, enzyme-linked immunosorbent assay
Trans. Vis. Sci. Tech.. 2024; 13(8):30. https://doi.org/10.1167/tvst.13.8.30

Includes: Supplemental Content

Glaucoma August 2024

Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization

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Sijie Zhao; Qing Dai; Zixuan Rao; Juan Li; Aiqin Wang; Ziqing Gao; Yuchen Fan
TAGS: biological markers, open-angle glaucoma, mendelian randomization analysis, genes, bioinformatics, optic nerve, dna methylation
Trans. Vis. Sci. Tech.. 2024; 13(8):21. https://doi.org/10.1167/tvst.13.8.21

Includes: Supplemental Content

Retina August 2024

Ocular and Serum Profiles of Inflammatory Molecules Associated With Retinitis Pigmentosa

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Yan Tao; Masatoshi Fukushima; Sakurako Shimokawa; Huanyu Zhao; Ayako Okita; Kohta Fujiwara; Atsunobu Takeda; Shizuo Mukai; Koh-Hei Sonoda; Yusuke Murakami
TAGS: aqueous humor, chemokines, cytokine, molecule, retinitis pigmentosa, interleukin-23, interleukin-8
Trans. Vis. Sci. Tech.. 2024; 13(8):18. https://doi.org/10.1167/tvst.13.8.18

Includes: Supplemental Content

Methods August 2024

Genetic Influence of Oily Fish Intake on Age-Related Macular Degeneration Risk: A Two-Sample Mendelian Randomization Analysis

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Miaoran Gao; Jian Zhou; Jingru Zhao; Zihao Liu; Xianke Luo; Changlu Yang; Xinning Yu; Mengdan Tang; Jiamei Zhu; Xiaoling Yan
TAGS: age-related macular degeneration, fatty fish, genetics, mendelian randomization analysis, instrumental variables
Trans. Vis. Sci. Tech.. 2024; 13(8):14. https://doi.org/10.1167/tvst.13.8.14

Includes: Supplemental Content

Retina August 2024

Identification of the Metabolic Signature of Aging Retina

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Wan Mu; Xiaoyan Han; Ming Tong; Shuai Ben; Mudi Yao; Ya Zhao; Jiao Xia; Ling Ren; Chang Huang; Duo Li; Xiumiao Li; Qin Jiang; Biao Yan
TAGS: aging, metabolites, retina
Trans. Vis. Sci. Tech.. 2024; 13(8):8. https://doi.org/10.1167/tvst.13.8.8

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Lens July 2024

Construction and Identification of a Novel Mice Model of Microphthalmia

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Dan Li; Kaiwen Cheng; Xiangjia Zhu
TAGS: lens (device), mice, microphthalmos, lens, crystalline, zinc finger protein gli3
Trans. Vis. Sci. Tech.. 2024; 13(7):11. https://doi.org/10.1167/tvst.13.7.11

Includes: Supplemental Content

Retina June 2024

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

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Björn Titz; Juliane Siebourg-Polster; Francois Bartolo; Vincent Lavergne; Zhiwen Jiang; Javier Gayan; Lebriz Altay; Philip Enders; Christoph Schmelzeisen; Quynh-Trang Ippisch; Michael Janusz Koss; Siamak Ansari-Shahrezaei; Justus Gerhard Garweg; Sascha Fauser; Andreas Dieckmann
TAGS: aqueous humor, hypertension, mass or substance concentration per volume, proteins, retinal diseases, lens (device), lens, crystalline, metabolomics, phenylephrine
Trans. Vis. Sci. Tech.. 2024; 13(6):17. https://doi.org/10.1167/tvst.13.6.17

Includes: Supplemental Content

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Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork

An Alternative Mechanism for the Anti-Myopia Effectiveness of Diffusion Optics Technology (DOT) Lenses

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

Reviewers

Associations of Metabolically Healthy Obesity and Retinal Age Gap

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

Model Predictive Temperature Control for Retinal Laser Treatments

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method

Comparison of SNCG and NEFH Promoter–Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma

Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology

Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization

Ocular and Serum Profiles of Inflammatory Molecules Associated With Retinitis Pigmentosa

Genetic Influence of Oily Fish Intake on Age-Related Macular Degeneration Risk: A Two-Sample Mendelian Randomization Analysis

Identification of the Metabolic Signature of Aging Retina

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Construction and Identification of a Novel Mice Model of Microphthalmia

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

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