Biochemistry and Molecular Biology

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Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

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Peng Xu; Chifune Kai; Satoshi Kawasaki; Yuki Kobayashi; Kouji Yamamoto; Motokazu Tsujikawa; Ryuhei Hayashi; Kohji Nishida
TAGS: proteins, epcam gene, corneal epithelial cells, antibodies, epithelial cell adhesion molecule, genes, epithelium, cornea
Trans. Vis. Sci. Tech.. 2018; 7(6):30. doi: 10.1167/tvst.7.6.30

Articles December 2018

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

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Sascha Dammeier; Peter Martus; Franziska Klose; Michael Seid; Dario Bosch; Janina D‘Alvise; Focke Ziemssen; Spyridon Dimopoulos; Marius Ueffing
TAGS: eye, proteins, metabolites
Trans. Vis. Sci. Tech.. 2018; 7(6):22. doi: 10.1167/tvst.7.6.22

Includes: Supplemental Content

Articles October 2018

Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold

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Juan Yang; Jung Woo Park; Dejin Zheng; Ren-He Xu
TAGS: immunohistochemistry, embryonic stem cells, epithelium, cornea, eye, mice
Trans. Vis. Sci. Tech.. 2018; 7(5):23. doi: 10.1167/tvst.7.5.23

Includes: Supplemental Content

Review September 2018

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

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Gabriel Velez; Peter H. Tang; Thiago Cabral; Galaxy Y. Cho; Daniel A. Machlab; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: biological markers, health, body tissue, vitreous body, eye, proteins, proteomics, vitreoretinal disease, precision
Trans. Vis. Sci. Tech.. 2018; 7(5):12. doi: 10.1167/tvst.7.5.12

Articles August 2018

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

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Nobuo Machinaga; Gary W. Ashley; Ralph Reid; Atsushi Yamasaki; Kyosuke Tanaka; Koichi Nakamura; Yoshiyuki Yabe; Yasushi Yoshigae; Daniel V. Santi
TAGS: half-life, injections, oryctolagus cuniculus, vitreous body, eye, molecule
Trans. Vis. Sci. Tech.. 2018; 7(4):21. doi: 10.1167/tvst.7.4.21

Includes: Supplemental Content

Articles February 2018

The Effects of Glaucoma Drainage Devices on Oxygen Tension, Glycolytic Metabolites, and Metabolomics Profile of Aqueous Humor in the Rabbit

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Blake K. Williamson; Nathan M. Hawkey; Diane A. Blake; Joshua W. Frenkel; Kevin P. McDaniel; Justin K. Davis; Celine Satija; Alex Beazer; Suraj Dhungana; James Carlson; Susan McRitchie; Ramesh S. Ayyala
TAGS: oxygen, glucose, glaucoma drainage implants, lactates, oryctolagus cuniculus, surgical procedures, operative, aqueous humor, eye, arterial oxygen tension, metabolites, metabolomics
Trans. Vis. Sci. Tech.. 2018; 7(1):14. doi: 10.1167/tvst.7.1.14

Includes: Supplemental Content

Articles October 2017

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

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Yu-Chi Liu; Anthony Herr Cheun Ng; Xu Wen Ng; Peng Yan; Subbu S. Venkatraman; Jodhbir S. Mehta; Tina T. Wong
TAGS: acetates, plasma, prednisolone, primates, eye, hematology, toxicokinetics, implantation procedure, histopathology tests, implants
Trans. Vis. Sci. Tech.. 2017; 6(5):9. doi: 10.1167/tvst.6.5.9

Includes: Supplemental Content

Articles July 2017

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

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Justine R. Smith; Shawn Todd; Liam M. Ashander; Theodosia Charitou; Yuefang Ma; Steven Yeh; Ian Crozier; Michael Z. Michael; Binoy Appukuttan; Keryn A. Williams; David J. Lynn; Glenn A. Marsh
TAGS: ebola virus, infection, eye, retinal pigment cell
Trans. Vis. Sci. Tech.. 2017; 6(4):12. doi: 10.1167/tvst.6.4.12

Includes: Supplemental Content

Review May 2017

CRISPR-Cas Genome Surgery in Ophthalmology

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James E. DiCarlo; Jesse D. Sengillo; Sally Justus; Thiago Cabral; Stephen H. Tsang; Vinit B. Mahajan
TAGS: genome, ophthalmology, surgical procedures, operative, eye, surgery specialty, crispr
Trans. Vis. Sci. Tech.. 2017; 6(3):13. doi: 10.1167/tvst.6.3.13

Letters to the Editor April 2017

Dramatic Effect of Oral CSF-1R Kinase Inhibitor on Retinal Microglia Revealed by In Vivo Scanning Laser Ophthalmoscopy

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Andreas Ebneter; Despina Kokona; Joël Jovanovic; Martin S. Zinkernagel
TAGS: microglia, kinase inhibitor, scanning laser ophthalmoscopy
Trans. Vis. Sci. Tech.. 2017; 6(2):10. doi: 10.1167/tvst.6.2.10

Includes: Supplemental Content

Articles January 2017

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

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Amy P. Lynch; Mark Ahearne
TAGS: western blotting, cell proliferation, stem cells, tretinoin, keratocytes
Trans. Vis. Sci. Tech.. 2017; 6(1):6. doi: 10.1167/tvst.6.1.6

Includes: Supplemental Content

Articles November 2016

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

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Alex S. Huang; Sindhu Saraswathy; Anna Dastiridou; Alan Begian; Hanz Legaspi; Chirayu Mohindroo; James C. H. Tan; Brian A. Francis; Joseph Caprioli; David R. Hinton; Robert N. Weinreb
TAGS: angiogram, cattle, fluorescein, indocyanine green, eye
Trans. Vis. Sci. Tech.. 2016; 5(6):5. doi: 10.1167/tvst.5.6.5

Articles April 2016

Titanium Coating of the Boston Keratoprosthesis

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Borja Salvador-Culla; Kyung Jae Jeong; Paraskevi Evi Kolovou; Homer H. Chiang; James Chodosh; Claes H. Dohlman; Daniel S. Kohane
TAGS: adhesions, polymethyl methacrylate, titanium, cornea
Trans. Vis. Sci. Tech.. 2016; 5(2):17. doi: 10.1167/tvst.5.2.17

Perspective March 2016

VEGF and Intraocular Neovascularization: From Discovery to Therapy

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Napoleone Ferrara
TAGS: vascular endothelial growth factor a, neovascularization, pathologic
Trans. Vis. Sci. Tech.. 2016; 5(2):10. doi: 10.1167/tvst.5.2.10

Articles February 2016

A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented Mouse Eyes

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Soo-Young Kim; Juthaporn Assawachananont
TAGS: hydrogen peroxide, melanins, body tissue, diagnostic imaging, eye, mice, retina, retinal pigment epithelium
Trans. Vis. Sci. Tech.. 2016; 5(1):6. doi: 10.1167/tvst.5.1.6

Articles November 2015

Conjunctivally Applied BDNF Protects Photoreceptors from Light-Induced Damage

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Elisa Cerri; Nicola Origlia; Benedetto Falsini; Davide Barloscio; Carlotta Fabiani; Marco Sansò; Sara Ottino; Luca Giovannini; Luciano Domenici
TAGS: brain-derived neurotrophic factor, photoreceptors, eye
Trans. Vis. Sci. Tech.. 2015; 4(6):1. doi: 10.1167/tvst.4.6.1

Articles May 2015

Nonantibestrophin Anti-RPE Antibodies in Paraneoplastic Exudative Polymorphous Vitelliform Maculopathy

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Lauren A. Dalvin; Adiv A. Johnson; Jose S. Pulido; Ranjit Dhaliwal; Alan D. Marmorstein
TAGS: western blotting, autoantibodies, fluorescent antibody technique, antibodies, macular disorders
Trans. Vis. Sci. Tech.. 2015; 4(3):2. doi: 10.1167/tvst.4.3.2

Articles November 2013

Optimization of Ex Vivo Expansion of Limbal Epithelial Progenitors by Maintaining Native Niche Cells on Denuded Amniotic Membrane

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Szu-Yu Chen; Megha Mahabole; Scheffer C. G. Tseng
TAGS: epithelium, amnion, collagenase, zinostatin
Trans. Vis. Sci. Tech.. 2013; 2(7):1. doi: 10.1167/tvst.2.7.1

Includes: Supplemental Content

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Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

The Effects of Glaucoma Drainage Devices on Oxygen Tension, Glycolytic Metabolites, and Metabolomics Profile of Aqueous Humor in the Rabbit

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

CRISPR-Cas Genome Surgery in Ophthalmology

Dramatic Effect of Oral CSF-1R Kinase Inhibitor on Retinal Microglia Revealed by In Vivo Scanning Laser Ophthalmoscopy

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

Titanium Coating of the Boston Keratoprosthesis

VEGF and Intraocular Neovascularization: From Discovery to Therapy

A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented Mouse Eyes

Conjunctivally Applied BDNF Protects Photoreceptors from Light-Induced Damage

Nonantibestrophin Anti-RPE Antibodies in Paraneoplastic Exudative Polymorphous Vitelliform Maculopathy

Optimization of Ex Vivo Expansion of Limbal Epithelial Progenitors by Maintaining Native Niche Cells on Denuded Amniotic Membrane

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