Biochemistry and Molecular Biology

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Articles December 2018

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

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Sascha Dammeier; Peter Martus; Franziska Klose; Michael Seid; Dario Bosch; Janina D‘Alvise; Focke Ziemssen; Spyridon Dimopoulos; Marius Ueffing
TAGS: eye, proteins, metabolites
Trans. Vis. Sci. Tech.. 2018; 7(6):22. doi: 10.1167/tvst.7.6.22

Includes: Supplemental Content

Articles October 2018

Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold

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Juan Yang; Jung Woo Park; Dejin Zheng; Ren-He Xu
TAGS: immunohistochemistry, embryonic stem cells, epithelium, cornea, eye, mice
Trans. Vis. Sci. Tech.. 2018; 7(5):23. doi: 10.1167/tvst.7.5.23

Includes: Supplemental Content

Review September 2018

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

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Gabriel Velez; Peter H. Tang; Thiago Cabral; Galaxy Y. Cho; Daniel A. Machlab; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: biological markers, health, body tissue, vitreous body, eye, proteins, proteomics, vitreoretinal disease, precision
Trans. Vis. Sci. Tech.. 2018; 7(5):12. doi: 10.1167/tvst.7.5.12

Articles August 2018

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

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Nobuo Machinaga; Gary W. Ashley; Ralph Reid; Atsushi Yamasaki; Kyosuke Tanaka; Koichi Nakamura; Yoshiyuki Yabe; Yasushi Yoshigae; Daniel V. Santi
TAGS: half-life, injections, oryctolagus cuniculus, vitreous body, eye, molecule
Trans. Vis. Sci. Tech.. 2018; 7(4):21. doi: 10.1167/tvst.7.4.21

Includes: Supplemental Content

Articles February 2018

The Effects of Glaucoma Drainage Devices on Oxygen Tension, Glycolytic Metabolites, and Metabolomics Profile of Aqueous Humor in the Rabbit

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Blake K. Williamson; Nathan M. Hawkey; Diane A. Blake; Joshua W. Frenkel; Kevin P. McDaniel; Justin K. Davis; Celine Satija; Alex Beazer; Suraj Dhungana; James Carlson; Susan McRitchie; Ramesh S. Ayyala
TAGS: oxygen, glucose, glaucoma drainage implants, lactates, oryctolagus cuniculus, surgical procedures, operative, aqueous humor, eye, arterial oxygen tension, metabolites, metabolomics
Trans. Vis. Sci. Tech.. 2018; 7(1):14. doi: 10.1167/tvst.7.1.14

Includes: Supplemental Content

Articles October 2017

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

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Yu-Chi Liu; Anthony Herr Cheun Ng; Xu Wen Ng; Peng Yan; Subbu S. Venkatraman; Jodhbir S. Mehta; Tina T. Wong
TAGS: acetates, plasma, prednisolone, primates, eye, hematology, toxicokinetics, implantation procedure, histopathology tests, implants
Trans. Vis. Sci. Tech.. 2017; 6(5):9. doi: 10.1167/tvst.6.5.9

Includes: Supplemental Content

Articles July 2017

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

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Justine R. Smith; Shawn Todd; Liam M. Ashander; Theodosia Charitou; Yuefang Ma; Steven Yeh; Ian Crozier; Michael Z. Michael; Binoy Appukuttan; Keryn A. Williams; David J. Lynn; Glenn A. Marsh
TAGS: ebola virus, infection, eye, retinal pigment cell
Trans. Vis. Sci. Tech.. 2017; 6(4):12. doi: 10.1167/tvst.6.4.12

Includes: Supplemental Content

Review May 2017

CRISPR-Cas Genome Surgery in Ophthalmology

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James E. DiCarlo; Jesse D. Sengillo; Sally Justus; Thiago Cabral; Stephen H. Tsang; Vinit B. Mahajan
TAGS: genome, ophthalmology, surgical procedures, operative, eye, surgery specialty, crispr
Trans. Vis. Sci. Tech.. 2017; 6(3):13. doi: 10.1167/tvst.6.3.13

Letters to the Editor April 2017

Dramatic Effect of Oral CSF-1R Kinase Inhibitor on Retinal Microglia Revealed by In Vivo Scanning Laser Ophthalmoscopy

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Andreas Ebneter; Despina Kokona; Joël Jovanovic; Martin S. Zinkernagel
TAGS: microglia, kinase inhibitor, scanning laser ophthalmoscopy
Trans. Vis. Sci. Tech.. 2017; 6(2):10. doi: 10.1167/tvst.6.2.10

Includes: Supplemental Content

Articles January 2017

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

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Amy P. Lynch; Mark Ahearne
TAGS: western blotting, cell proliferation, stem cells, tretinoin, keratocytes
Trans. Vis. Sci. Tech.. 2017; 6(1):6. doi: 10.1167/tvst.6.1.6

Includes: Supplemental Content

Articles November 2016

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

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Alex S. Huang; Sindhu Saraswathy; Anna Dastiridou; Alan Begian; Hanz Legaspi; Chirayu Mohindroo; James C. H. Tan; Brian A. Francis; Joseph Caprioli; David R. Hinton; Robert N. Weinreb
TAGS: angiogram, cattle, fluorescein, indocyanine green, eye
Trans. Vis. Sci. Tech.. 2016; 5(6):5. doi: 10.1167/tvst.5.6.5

Articles April 2016

Titanium Coating of the Boston Keratoprosthesis

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Borja Salvador-Culla; Kyung Jae Jeong; Paraskevi Evi Kolovou; Homer H. Chiang; James Chodosh; Claes H. Dohlman; Daniel S. Kohane
TAGS: adhesions, polymethyl methacrylate, titanium, cornea
Trans. Vis. Sci. Tech.. 2016; 5(2):17. doi: 10.1167/tvst.5.2.17

Perspective March 2016

VEGF and Intraocular Neovascularization: From Discovery to Therapy

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Napoleone Ferrara
TAGS: vascular endothelial growth factor a, neovascularization, pathologic
Trans. Vis. Sci. Tech.. 2016; 5(2):10. doi: 10.1167/tvst.5.2.10

Articles February 2016

A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented Mouse Eyes

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Soo-Young Kim; Juthaporn Assawachananont
TAGS: hydrogen peroxide, melanins, body tissue, diagnostic imaging, eye, mice, retina, retinal pigment epithelium
Trans. Vis. Sci. Tech.. 2016; 5(1):6. doi: 10.1167/tvst.5.1.6

Articles November 2015

Conjunctivally Applied BDNF Protects Photoreceptors from Light-Induced Damage

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Elisa Cerri; Nicola Origlia; Benedetto Falsini; Davide Barloscio; Carlotta Fabiani; Marco Sansò; Sara Ottino; Luca Giovannini; Luciano Domenici
TAGS: brain-derived neurotrophic factor, photoreceptors, eye
Trans. Vis. Sci. Tech.. 2015; 4(6):1. doi: 10.1167/tvst.4.6.1

Articles May 2015

Nonantibestrophin Anti-RPE Antibodies in Paraneoplastic Exudative Polymorphous Vitelliform Maculopathy

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Lauren A. Dalvin; Adiv A. Johnson; Jose S. Pulido; Ranjit Dhaliwal; Alan D. Marmorstein
TAGS: western blotting, autoantibodies, fluorescent antibody technique, antibodies, macular disorders
Trans. Vis. Sci. Tech.. 2015; 4(3):2. doi: 10.1167/tvst.4.3.2

Articles November 2013

Optimization of Ex Vivo Expansion of Limbal Epithelial Progenitors by Maintaining Native Niche Cells on Denuded Amniotic Membrane

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Szu-Yu Chen; Megha Mahabole; Scheffer C. G. Tseng
TAGS: epithelium, amnion, collagenase, zinostatin
Trans. Vis. Sci. Tech.. 2013; 2(7):1. doi: 10.1167/tvst.2.7.1

Includes: Supplemental Content

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Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

The Effects of Glaucoma Drainage Devices on Oxygen Tension, Glycolytic Metabolites, and Metabolomics Profile of Aqueous Humor in the Rabbit

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

CRISPR-Cas Genome Surgery in Ophthalmology

Dramatic Effect of Oral CSF-1R Kinase Inhibitor on Retinal Microglia Revealed by In Vivo Scanning Laser Ophthalmoscopy

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

Titanium Coating of the Boston Keratoprosthesis

VEGF and Intraocular Neovascularization: From Discovery to Therapy

A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented Mouse Eyes

Conjunctivally Applied BDNF Protects Photoreceptors from Light-Induced Damage

Nonantibestrophin Anti-RPE Antibodies in Paraneoplastic Exudative Polymorphous Vitelliform Maculopathy

Optimization of Ex Vivo Expansion of Limbal Epithelial Progenitors by Maintaining Native Niche Cells on Denuded Amniotic Membrane

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