Biochemistry and Molecular Biology

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Articles April 2022

Derivation and Characterization of Murine and Amphibian Müller Glia Cell Lines

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Ryan A. Gallo; Farhan Qureshi; Thomas A. Strong; Steven H. Lang; Kevin A. Pino; Galina Dvoriantchikova; Daniel Pelaez
TAGS: amphibia, anura, calcium, cell lines, mice, neuroglia, signal transduction, retina
Trans. Vis. Sci. Tech.. 2022; 11(4):4. doi: https://doi.org/10.1167/tvst.11.4.4

Includes: Multimedia, Supplemental Content

Editorial March 2022

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2022; 11(3):25. doi: https://doi.org/10.1167/tvst.11.3.25

Articles March 2022

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study

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Maria Consiglia Trotta; Carlo Gesualdo; Francesco Petrillo; Giancuomo Cavasso; Alberto Della Corte; Giovanbattista D'Amico; Anca Hermenean; Francesca Simonelli; Settimio Rossi
TAGS: biological markers, diabetes mellitus, diabetic retinopathy, hepatorenal syndrome, hrs trial, pilot projects, cytokine, nonproliferative diabetic retinopathy, arginase, chemokines
Trans. Vis. Sci. Tech.. 2022; 11(3):16. doi: https://doi.org/10.1167/tvst.11.3.16

Articles March 2022

Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns

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Benjamin K. Young; Liangbo L. Shen; Lucian V. Del Priore
TAGS: diffusion, digestive tract decontamination, transcriptional activation, kinetics
Trans. Vis. Sci. Tech.. 2022; 11(3):5. doi: https://doi.org/10.1167/tvst.11.3.5

Articles February 2022

A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers’ Serum on RPE Cells With AMD High-Risk Alleles

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Bincui Cai; Zhe Zhang; Shuo Sun; Tingting Lin; Yifeng Ke; Zhiqing Li; Jin Yang; Xiaorong Li
TAGS: alleles, caveolins, cigarettes, environmental factors, proteomics, retinal pigment cell, smokers, htra1 gene, proteins
Trans. Vis. Sci. Tech.. 2022; 11(2):15. doi: https://doi.org/10.1167/tvst.11.2.15

Includes: Supplemental Content

Articles February 2022

Sex Differences in RANTES (CCL5) in Patients With Intermediate Age-Related Macular Degeneration (AMD) and Controls With no AMD

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Cheryl N. Fonteh; Alan G. Palestine; Brandie D. Wagner; Jennifer L. Patnaik; Marc T. Mathias; Naresh Mandava; Rebecca Baldermann; Anne M. Lynch; for the University of Colorado Retina Research Group
TAGS: age-related macular degeneration, rantes, sex characteristics
Trans. Vis. Sci. Tech.. 2022; 11(2):12. doi: https://doi.org/10.1167/tvst.11.2.12

Articles February 2022

Targeting NECTIN-1 Based on CRISPR/Cas9 System Attenuated the Herpes Simplex Virus Infection in Human Corneal Epithelial Cells In Vitro

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Yue Li; Yuda Wei; Gang Li; Shiqian Huang; Jianjiang Xu; Qiurong Ding; Jiaxu Hong
TAGS: crispr, herpes simplex infection, nectins, corneal epithelial cells, attenuation
Trans. Vis. Sci. Tech.. 2022; 11(2):8. doi: https://doi.org/10.1167/tvst.11.2.8

Includes: Supplemental Content

Articles January 2022

Association of Keratin 8 Level in Aqueous Humor With Outcomes of Intravitreal Ranibizumab Treatment for Neovascular Age-Related Macular Degeneration

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Joo Youn Shin; Jonghyun Lee; Jinkyu Park; Min Kim; Hyewon Chung; Suk Ho Byeon
TAGS: age-related macular degeneration, cytokeratin 8, exudative age-related macular degeneration, hypertension, ranibizumab, treatment outcome, aqueous humor, injections
Trans. Vis. Sci. Tech.. 2022; 11(1):26. doi: https://doi.org/10.1167/tvst.11.1.26

Includes: Supplemental Content

Special Issue November 2021

Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival

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Anat Nitzan; Miriam Corredor-Sanchez; Ronit Galron; Limor Nahary; Mary Safrin; Marina Bruzel; Alejandra Moure; Roman Bonet; Yolanda Pérez; Jordi Bujons; Enriqueta Vallejo-Yague; Hagit Sacks; Michael Burnet; Ignacio Alfonso; Angel Messeguer; Itai Benhar; Ari Barzilai; Arieh S. Solomon
TAGS: antibodies, cell motility, implants, semaphorin-3a, retinal ganglion cells, axotomy, optic nerve, eye
Trans. Vis. Sci. Tech.. 2021; 10(10):16. doi: https://doi.org/10.1167/tvst.10.10.16

Includes: Supplemental Content

Articles November 2021

Changes After a Month Following Micropulse Cyclophotocoagulation in Normal Porcine Eyes

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So Min Ahn; Mihyun Choi; Seong-Woo Kim; Yong Yeon Kim
TAGS: ciliary muscle, eye, immunohistochemistry, lasers, photocoagulation of ciliary body, poly(adp-ribose) polymerases, retina, suidae, uvea, laser therapy
Trans. Vis. Sci. Tech.. 2021; 10(13):11. doi: https://doi.org/10.1167/tvst.10.13.11

Includes: Supplemental Content

Articles November 2021

Progression of Geographic Atrophy: Epistemic Uncertainties Affecting Mathematical Models and Machine Learning

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Janan Arslan; Kurt K. Benke
TAGS: atrophy, machine learning, mathematical model, taxonomic classification
Trans. Vis. Sci. Tech.. 2021; 10(13):3. doi: https://doi.org/10.1167/tvst.10.13.3

Clinical Trials September 2021

Integrating Clinical Data and Tear Proteomics to Assess Efficacy, Ocular Surface Status, and Biomarker Response After Orthokeratology Lens Wear

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Jimmy S.H. Tse; Jimmy K.W. Cheung; Gigi T.K. Wong; Thomas C. Lam; Kai Yip Choi; Katherine H.Y. So; Christie D.M. Lam; Andes Y.H. Sze; Angel C.K. Wong; Gigi M.C. Yee; Henry H.L. Chan
TAGS: biological markers, lens (device), lens, crystalline, orthokeratology, proteins, proteome, proteomics, safety, cornea
Trans. Vis. Sci. Tech.. 2021; 10(11):18. doi: https://doi.org/10.1167/tvst.10.11.18

Includes: Supplemental Content

Special Issue September 2021

In Vivo Subretinal ARPE-19 Cell Tracking Using Indocyanine Green Contrast-Enhanced Multimodality Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence Imaging for Regenerative Medicine

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Van Phuc Nguyen; Yanxiu Li; Jessica Henry; Thomas Qian; Wei Zhang; Xueding Wang; Yannis M. Paulus
TAGS: diagnostic imaging, fluorescence, indocyanine green, injections, optical coherence tomography, cell tracking, regenerative medicine
Trans. Vis. Sci. Tech.. 2021; 10(10):10. doi: https://doi.org/10.1167/tvst.10.10.10

Articles August 2021

Comparison of Syringes With Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates in Brolucizumab, Aflibercept and Bevacizumab

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Marc Schargus; Katharina Tatjana Kopp; Constanze Helbig; Andreas Frings; Gerhard Winter
TAGS: aflibercept, anti-vascular endothelial growth factor therapy, bevacizumab, brolucizumab, syringes, protein aggregates, vial
Trans. Vis. Sci. Tech.. 2021; 10(9):21. doi: https://doi.org/10.1167/tvst.10.9.21

Special Issue July 2021

Biomechanics of Ophthalmic Crosslinking

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Brecken J. Blackburn; Andrew M. Rollins; William J. Dupps, Jr.
TAGS: biomechanics, body tissue, cornea, corneal collagen cross-linking, eye, riboflavin, ultraviolet a radiation, sclera
Trans. Vis. Sci. Tech.. 2021; 10(5):8. doi: https://doi.org/10.1167/tvst.10.5.8

Articles July 2021

Diagnosis of Ocular Toxocariasis by Serum and Aqueous Humor IgG ELISA

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Li Huang; Limei Sun; Chengxi Liu; Songshan Li; Ting Zhang; Xiaoling Luo; Xiaoyan Ding
TAGS: immunoglobulin g, toxocara, ocular larva migrans, enzyme-linked immunosorbent assay, aqueous humor
Trans. Vis. Sci. Tech.. 2021; 10(8):33. doi: https://doi.org/10.1167/tvst.10.8.33

Includes: Supplemental Content

Articles July 2021

Computational Fluid Dynamics of Intraocular Silicone Oil Tamponade

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Tommaso Rossi; Giorgio Querzoli; Maria Grazia Badas; Federico Angius; Serena Telani; Guido Ripandelli
TAGS: retina, shear stress, silicone oils, fluid dynamics, eye
Trans. Vis. Sci. Tech.. 2021; 10(8):22. doi: https://doi.org/10.1167/tvst.10.8.22

Includes: Multimedia, Supplemental Content

Editorial July 2021

Data Science in Translational Vision Science and Technology

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Marco A. Zarbin; Aaron Y. Lee; Pearse A. Keane; Michael F. Chiang
TAGS: data science, technology, vision
Trans. Vis. Sci. Tech.. 2021; 10(8):20. doi: https://doi.org/10.1167/tvst.10.8.20

Articles July 2021

Immunoprofiling of Nonarteritic Anterior Ischemic Optic Neuropathy

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Louise A. Mesentier-Louro; Laurel Stell; Yan Yan; Artis A. Montague; Vinicio de Jesus Perez; Yaping Joyce Liao
TAGS: inflammation, nonarteritic anterior ischemic optic neuropathy, optic neuropathy, ischemic
Trans. Vis. Sci. Tech.. 2021; 10(8):17. doi: https://doi.org/10.1167/tvst.10.8.17

Includes: Supplemental Content

Articles July 2021

Comparison of Clinical and Biomechanical Outcomes of Small Incision Lenticule Extraction With 120- and 140-µm Cap Thickness

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Ikhyun Jun; David Sung Yong Kang; Cynthia J. Roberts; Hun Lee; Seung Ki Jean; Eung Kweon Kim; Kyoung Yul Seo; Tae-im Kim
TAGS: cornea, eye, postoperative care, refraction, visual acuity, surgical procedures, operative, safety, biomechanics, treatment outcome, nomogram
Trans. Vis. Sci. Tech.. 2021; 10(8):15. doi: https://doi.org/10.1167/tvst.10.8.15

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Derivation and Characterization of Murine and Amphibian Müller Glia Cell Lines

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study

Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns

A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers’ Serum on RPE Cells With AMD High-Risk Alleles

Sex Differences in RANTES (CCL5) in Patients With Intermediate Age-Related Macular Degeneration (AMD) and Controls With no AMD

Targeting NECTIN-1 Based on CRISPR/Cas9 System Attenuated the Herpes Simplex Virus Infection in Human Corneal Epithelial Cells In Vitro

Association of Keratin 8 Level in Aqueous Humor With Outcomes of Intravitreal Ranibizumab Treatment for Neovascular Age-Related Macular Degeneration

Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival

Changes After a Month Following Micropulse Cyclophotocoagulation in Normal Porcine Eyes

Progression of Geographic Atrophy: Epistemic Uncertainties Affecting Mathematical Models and Machine Learning

Integrating Clinical Data and Tear Proteomics to Assess Efficacy, Ocular Surface Status, and Biomarker Response After Orthokeratology Lens Wear

In Vivo Subretinal ARPE-19 Cell Tracking Using Indocyanine Green Contrast-Enhanced Multimodality Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence Imaging for Regenerative Medicine

Comparison of Syringes With Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates in Brolucizumab, Aflibercept and Bevacizumab

Biomechanics of Ophthalmic Crosslinking

Diagnosis of Ocular Toxocariasis by Serum and Aqueous Humor IgG ELISA

Computational Fluid Dynamics of Intraocular Silicone Oil Tamponade

Data Science in Translational Vision Science and Technology

Immunoprofiling of Nonarteritic Anterior Ischemic Optic Neuropathy

Comparison of Clinical and Biomechanical Outcomes of Small Incision Lenticule Extraction With 120- and 140-µm Cap Thickness

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