Biochemistry and Molecular Biology

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Cornea & External Disease September 2024

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

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Yuan Chang; Tianze Huang; Shan Yang; Ying Li; Di Chen
TAGS: atopic dermatitis, keratoconus, mendelian randomization analysis, genome-wide association study, datasets
Trans. Vis. Sci. Tech.. 2024; 13(9):13. https://doi.org/10.1167/tvst.13.9.13

Includes: Supplemental Content

Artificial Intelligence September 2024

Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method

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Najung Kim; Minsub Lee; Hyewon Chung; Hyung Chan Kim; Hyungwoo Lee
TAGS: age-related macular degeneration, anti-vascular endothelial growth factor therapy, cohort studies, diagnostic imaging, drug loading dose, injections, machine learning, visual acuity, treatment protocols, eye
Trans. Vis. Sci. Tech.. 2024; 13(9):3. https://doi.org/10.1167/tvst.13.9.3

Includes: Supplemental Content

Glaucoma August 2024

Comparison of SNCG and NEFH Promoter–Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma

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Nuala O'Neill; Miranda Meng; Brahim Chaqour; Kimberly Dine; Neha Sarabu; Jennifer C. Pham; Kenneth S. Shindler; Ahmara G. Ross
TAGS: glaucoma, mice, spatial vectors, enhancer of transcription, genes, cytomegalovirus
Trans. Vis. Sci. Tech.. 2024; 13(8):37. https://doi.org/10.1167/tvst.13.8.37

Retina August 2024

Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology

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Rami A. Shahror; Esraa Shosha; Marco H. Ji; Carol A. Morris; Melissa Wild; Bushra Zaman; Christian D. Mitchell; Pedro Tetelbom; Yuet-Kin Leung; Paul H. Phillips; Ahmed A. Sallam; Abdelrahman Y. Fouda
TAGS: aqueous humor, central retinal artery occlusion, hypertension, proteins, pathophysiology, clusterin, enzyme-linked immunosorbent assay
Trans. Vis. Sci. Tech.. 2024; 13(8):30. https://doi.org/10.1167/tvst.13.8.30

Includes: Supplemental Content

Glaucoma August 2024

Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization

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Sijie Zhao; Qing Dai; Zixuan Rao; Juan Li; Aiqin Wang; Ziqing Gao; Yuchen Fan
TAGS: biological markers, open-angle glaucoma, mendelian randomization analysis, genes, bioinformatics, optic nerve, dna methylation
Trans. Vis. Sci. Tech.. 2024; 13(8):21. https://doi.org/10.1167/tvst.13.8.21

Includes: Supplemental Content

Retina August 2024

Ocular and Serum Profiles of Inflammatory Molecules Associated With Retinitis Pigmentosa

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Yan Tao; Masatoshi Fukushima; Sakurako Shimokawa; Huanyu Zhao; Ayako Okita; Kohta Fujiwara; Atsunobu Takeda; Shizuo Mukai; Koh-Hei Sonoda; Yusuke Murakami
TAGS: aqueous humor, chemokines, cytokine, molecule, retinitis pigmentosa, interleukin-23, interleukin-8
Trans. Vis. Sci. Tech.. 2024; 13(8):18. https://doi.org/10.1167/tvst.13.8.18

Includes: Supplemental Content

Methods August 2024

Genetic Influence of Oily Fish Intake on Age-Related Macular Degeneration Risk: A Two-Sample Mendelian Randomization Analysis

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Miaoran Gao; Jian Zhou; Jingru Zhao; Zihao Liu; Xianke Luo; Changlu Yang; Xinning Yu; Mengdan Tang; Jiamei Zhu; Xiaoling Yan
TAGS: age-related macular degeneration, fatty fish, genetics, mendelian randomization analysis, instrumental variables
Trans. Vis. Sci. Tech.. 2024; 13(8):14. https://doi.org/10.1167/tvst.13.8.14

Includes: Supplemental Content

Retina August 2024

Identification of the Metabolic Signature of Aging Retina

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Wan Mu; Xiaoyan Han; Ming Tong; Shuai Ben; Mudi Yao; Ya Zhao; Jiao Xia; Ling Ren; Chang Huang; Duo Li; Xiumiao Li; Qin Jiang; Biao Yan
TAGS: aging, metabolites, retina
Trans. Vis. Sci. Tech.. 2024; 13(8):8. https://doi.org/10.1167/tvst.13.8.8

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Lens July 2024

Construction and Identification of a Novel Mice Model of Microphthalmia

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Dan Li; Kaiwen Cheng; Xiangjia Zhu
TAGS: lens (device), mice, microphthalmos, lens, crystalline, zinc finger protein gli3
Trans. Vis. Sci. Tech.. 2024; 13(7):11. https://doi.org/10.1167/tvst.13.7.11

Includes: Supplemental Content

Retina June 2024

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

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Björn Titz; Juliane Siebourg-Polster; Francois Bartolo; Vincent Lavergne; Zhiwen Jiang; Javier Gayan; Lebriz Altay; Philip Enders; Christoph Schmelzeisen; Quynh-Trang Ippisch; Michael Janusz Koss; Siamak Ansari-Shahrezaei; Justus Gerhard Garweg; Sascha Fauser; Andreas Dieckmann
TAGS: aqueous humor, hypertension, mass or substance concentration per volume, proteins, retinal diseases, lens (device), lens, crystalline, metabolomics, phenylephrine
Trans. Vis. Sci. Tech.. 2024; 13(6):17. https://doi.org/10.1167/tvst.13.6.17

Includes: Supplemental Content

Retina June 2024

Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide

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Ian L. McAllister; Sarojini Vijayasekaran; Samuel McLenachan; Riyaz Bhikoo; Fred K. Chen; Dan Zhang; Emily Kanagalingam; Dao-Yi Yu
TAGS: bevacizumab, cytokine, did not receive therapy or drug, eye, genes, proteins, rna, messenger, triamcinolone acetonide, vascular endothelial growth factor a, venous retinal branch occlusion
Trans. Vis. Sci. Tech.. 2024; 13(6):13. https://doi.org/10.1167/tvst.13.6.13

Public Health May 2024

Impact of Physical Activity Frequency, Duration, and Intensity on Senile Cataract Risk: A Mendelian Randomization Study

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Yuze Mi; Qinnan Zhu; Yuxiang Chen; Xinni Zheng; Minghui Wan; Yipao Li
TAGS: cataract, senile, mendelian randomization analysis, physical activity, gait, genome-wide association study
Trans. Vis. Sci. Tech.. 2024; 13(5):26. https://doi.org/10.1167/tvst.13.5.26

Includes: Supplemental Content

Cornea & External Disease May 2024

Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model

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Chih-Chien Hsu; Hao-Kai Chuang; Yu-Jer Hsiao; Pin-Hsuan Chiang; Szu-Wen Chen; Wei-Ting Luo; Yi-Ping Yang; Ping-Hsing Tsai; Shih-Jen Chen; Ai-Ru Hsieh; Shih-Hwa Chiou
TAGS: dry eye syndromes, genome, genome-wide association study, polygenic risk score
Trans. Vis. Sci. Tech.. 2024; 13(5):13. https://doi.org/10.1167/tvst.13.5.13

Includes: Supplemental Content

Retina May 2024

Complement Cascade 8 - Alpha and Calpain-2 in Extracellular Vesicles of Human Vitreous as Biomarkers of Infectious Endophthalmitis

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Dhanwini Rudraprasad; Velmurugan K; Jayabalan Nirmal; Md. Hasnat Ali; Joveeta Joseph
TAGS: bacterial endophthalmitis, biological markers, calpain, complement system proteins, endophthalmitis, extracellular vesicles, vitreous body
Trans. Vis. Sci. Tech.. 2024; 13(5):14. https://doi.org/10.1167/tvst.13.5.14

Pediatric Ophthalmology & Strabismus May 2024

Tear Proteomics in Infants at Risk of Retinopathy of Prematurity: A Feasibility Study

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Chloe Shipton; Julie Aitken; Samuel Atkinson; Richard Burchmore; Ruth Hamilton; Helen Mactier; Suzanne McGill; Eoghan Millar; Anne Cees Houtman
TAGS: feasibility studies, infant, lacerations, proteins, proteomics, retinopathy of prematurity, rupture, tears
Trans. Vis. Sci. Tech.. 2024; 13(5):1. https://doi.org/10.1167/tvst.13.5.1

Includes: Supplemental Content

Retina April 2024

Role of Hsa_circ_0000880 in the Regulation of High Glucose-Induced Apoptosis of Retinal Microvascular Endothelial Cells

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Jiawei Wang; Nannan Yang; Wanna Li; Han Zhang; Jianqiao Li
TAGS: apoptosis, circular rna, endothelial cells, glucose, epiretinal membrane, regulation
Trans. Vis. Sci. Tech.. 2024; 13(4):12. https://doi.org/10.1167/tvst.13.4.12

Glaucoma March 2024

Reduced Aqueous Humor Outflow Pathway Arborization in Childhood Glaucoma Eyes

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Shikha Gupta; Xiaowei Zhang; Arnav Panigrahi; Shakha; Raymond Fang; Clemens A. Strohmaier; Hao F. Zhang; Robert N. Weinreb; Viney Gupta; Alex S. Huang
TAGS: aqueous humor, eye, glaucoma, congenital, angiogram, adult, surgical procedures, operative, cataract
Trans. Vis. Sci. Tech.. 2024; 13(3):23. https://doi.org/10.1167/tvst.13.3.23

Includes: Supplemental Content

Glaucoma February 2024

Assessment of Causality Between Diet-Derived Antioxidants and Primary Open-Angle Glaucoma: A Mendelian Randomization Study

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Kun Xiong; Qi'ao Zhang; Huiyan Mao; Nathan Congdon; Yuanbo Liang
TAGS: antioxidants, diet, glaucoma, mendelian randomization analysis, open-angle glaucoma, instrumental variables, genetics
Trans. Vis. Sci. Tech.. 2024; 13(2):20. https://doi.org/10.1167/tvst.13.2.20

Includes: Supplemental Content

Cornea & External Disease February 2024

Detection of TTR Amyloid in the Conjunctiva Using a Novel Fluorescent Ocular Tracer

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Julie Pilotte; Alex S. Huang; Sami Khoury; Xiaowei Zhang; Ali Tafreshi; Peter Vanderklish; Stella T. Sarraf; Jose S. Pulido; Tatyana Milman
TAGS: amyloid, body tissue, conjunctiva, eye
Trans. Vis. Sci. Tech.. 2024; 13(2):11. https://doi.org/10.1167/tvst.13.2.11

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Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method

Comparison of SNCG and NEFH Promoter–Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma

Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology

Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization

Ocular and Serum Profiles of Inflammatory Molecules Associated With Retinitis Pigmentosa

Genetic Influence of Oily Fish Intake on Age-Related Macular Degeneration Risk: A Two-Sample Mendelian Randomization Analysis

Identification of the Metabolic Signature of Aging Retina

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Construction and Identification of a Novel Mice Model of Microphthalmia

Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide

Impact of Physical Activity Frequency, Duration, and Intensity on Senile Cataract Risk: A Mendelian Randomization Study

Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model

Complement Cascade 8 - Alpha and Calpain-2 in Extracellular Vesicles of Human Vitreous as Biomarkers of Infectious Endophthalmitis

Tear Proteomics in Infants at Risk of Retinopathy of Prematurity: A Feasibility Study

Role of Hsa_circ_0000880 in the Regulation of High Glucose-Induced Apoptosis of Retinal Microvascular Endothelial Cells

Reduced Aqueous Humor Outflow Pathway Arborization in Childhood Glaucoma Eyes

Assessment of Causality Between Diet-Derived Antioxidants and Primary Open-Angle Glaucoma: A Mendelian Randomization Study

Detection of TTR Amyloid in the Conjunctiva Using a Novel Fluorescent Ocular Tracer

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