Biochemistry and Molecular Biology

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Letters to the Editor August 2020

International Retinal Laser Society Guidelines For Subthreshold Laser Treatment

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Jan E. E. Keunen; Maurizio Battaglia-Parodi; Stela Vujosevic; Jeffrey K. Luttrull
TAGS: guidelines, laser therapy, lasers, societies
Trans. Vis. Sci. Tech.. 2020; 9(9):15. doi: https://doi.org/10.1167/tvst.9.9.15

Articles August 2020

DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents

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Yoshitaka Isumi; Shinko Hayashi; Tatsuya Inoue; Yasushi Yoshigae; Toshiyuki Sato; Jun Hasegawa; Toshinori Agatsuma
TAGS: angiogenesis, antibodies, anti-vascular endothelial growth factor therapy, choroidal neovascularization, lasers, eye, ranibizumab, macaca fascicularis
Trans. Vis. Sci. Tech.. 2020; 9(9):7. doi: https://doi.org/10.1167/tvst.9.9.7

Includes: Supplemental Content

Editorial July 2020

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2020; 9(8):r. doi: https://doi.org/10.1167/tvst.9.8.r

Articles July 2020

Expression Profiles of Inflammatory Cytokines in the Aqueous Humor of Children after Congenital Cataract Extraction

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Yinying Zhao; Xiaohui Deng; Pingjun Chang; Man Hu; Zhangliang Li; Fan Zhang; Xixia Ding; Yune Zhao
TAGS: cataract surgery, child, congenital cataract, cytokine, hypertension, eye, aqueous humor
Trans. Vis. Sci. Tech.. 2020; 9(8):3. doi: https://doi.org/10.1167/tvst.9.8.3

Articles July 2020

Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities

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Kazuhisa Yamada; Hiroki Kaneko; Hideyuki Shimizu; Ayana Suzumura; Rina Namba; Kei Takayama; Seina Ito; Masataka Sugimoto; Hiroko Terasaki
TAGS: aging, rna, tissue degeneration, lamivudine, interleukin-18, retinal pigment cell, anti-inflammatory agents, retinal pigment epithelium
Trans. Vis. Sci. Tech.. 2020; 9(8):1. doi: https://doi.org/10.1167/tvst.9.8.1

Articles June 2020

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

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Hongman Song; Yong Zeng; Sheik Pran Babu Sardar Pasha; Ronald A. Bush; Camasamudram Vijayasarathy; Haohua Qian; Lisa Wei; Henry E. Wiley; Zhijian Wu; Paul A. Sieving
TAGS: eye, retina, spatial vectors, transfer technique, oryctolagus cuniculus, mice, fibroblast growth factor 2, intravitreal injections
Trans. Vis. Sci. Tech.. 2020; 9(7):28. doi: https://doi.org/10.1167/tvst.9.7.28

Articles May 2020

Software for Quantifying and Batch Processing Images of Brn3a and RBPMS Immunolabelled Retinal Ganglion Cells in Retinal Wholemounts

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Chelsea Guymer; Lloyd Damp; Glyn Chidlow; John Wood; Yi Fan Tang; Robert Casson
TAGS: retina, retinal ganglion cells, software, cell count, immunohistochemistry
Trans. Vis. Sci. Tech.. 2020; 9(6):28. doi: https://doi.org/10.1167/tvst.9.6.28

Includes: Supplemental Content

Articles May 2020

A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population

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Brendan Miller; Mina Torres; Xuejuan Jiang; Roberta McKean-Cowdin; Darryl Nousome; Su-Jeong Kim; Hemal H. Mehta; Kelvin Yen; Pinchas Cohen; Rohit Varma
TAGS: cataract, genome-wide association study, hispanics or latinos, mitochondria
Trans. Vis. Sci. Tech.. 2020; 9(6):25. doi: https://doi.org/10.1167/tvst.9.6.25

Includes: Supplemental Content

Articles May 2020

Quantification of Growth Factors and Fibronectin in Diverse Preparations of Platelet-Rich Plasma for the Treatment of Ocular Surface Disorders (E-PRP)

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Alejandra E. Rodriguez; Sandra Gisbert; Antonio Palazón; Jorge L. Alio
TAGS: fibronectins, growth factor, platelet rich plasma, mass or substance concentration per volume
Trans. Vis. Sci. Tech.. 2020; 9(6):22. doi: https://doi.org/10.1167/tvst.9.6.22

Articles May 2020

Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

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Hyeong Min Kim; Seungmin Ha; Hye Kyoung Hong; Yoonha Hwang; Pilhan Kim; Eunsol Yang; Jae Yong Chung; Sunyoung Park; Young Joo Park; Kyu Hyung Park; Hyuncheol Kim; Se Joon Woo
TAGS: antibodies, eye, kinetics, molecule, nanoparticles, oryctolagus cuniculus, vitreous body, fluorescence, immunoglobulin g, intravitreal injections
Trans. Vis. Sci. Tech.. 2020; 9(6):20. doi: https://doi.org/10.1167/tvst.9.6.20

Includes: Supplemental Content

Articles May 2020

Development of Contact Lens-Shaped Crosslinked Amniotic Membranes for Sutureless Fixation in the Treatment of Ocular Surface Diseases

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Soojin Yi; Man-Il Huh; Hyeonjun Hong; Donghee Yoon; Han Sang Park; Dong Sung Kim; Hong Kyun Kim
TAGS: amnion, contact lenses, lens (device), lens, crystalline, mountain sickness, acute, growth factor, tensile strength
Trans. Vis. Sci. Tech.. 2020; 9(6):12. doi: https://doi.org/10.1167/tvst.9.6.12

Articles May 2020

Apigenin and Ethaverine Hydrochloride Enhance Retinal Vascular Barrier In Vitro and In Vivo

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Weiwei Jiang; Huan Chen; Zhengfu Tai; Tian Li; Ling Luo; Zongzhong Tong; Weiquan Zhu
TAGS: cadherins, cytokine, dimethyl sulfoxide, electric impedance, endothelial cells, enhancer of transcription, permeability, tissue membrane, body tissue, ribavirin
Trans. Vis. Sci. Tech.. 2020; 9(6):8. doi: https://doi.org/10.1167/tvst.9.6.8

Includes: Supplemental Content

Articles April 2020

Comparison of Subthreshold 577 and 810 nm Micropulse Laser Effects on Heat-Shock Protein Activation Kinetics: Implications for Treatment Efficacy and Safety

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David B. Chang; Jeffrey K. Luttrull
TAGS: heat-shock proteins, kinetics, lasers, safety, treatment effectiveness, laser therapy
Trans. Vis. Sci. Tech.. 2020; 9(5):23. doi: https://doi.org/10.1167/tvst.9.5.23

Includes: Supplemental Content

Articles April 2020

Evaluating the Correlation between Alzheimer's Amyloid-β Peptides and Glaucoma in Human Aqueous Humor

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Francesca Cappelli; Francesca Caudano; Maria Marenco; Valeria Testa; Alessandro Masala; Daniele Sindaco; Angelo Macrì; Carlo E. Traverso; Michele Iester; Roberta Ricciarelli
TAGS: alzheimer's disease, amyloid, aqueous humor, glaucoma, peptides, hypertension
Trans. Vis. Sci. Tech.. 2020; 9(5):21. doi: https://doi.org/10.1167/tvst.9.5.21

Articles March 2020

Safety Profile of Slit-Lamp-Delivered Retinal Laser Photobiomodulation

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Jack Ao; Glyn Chidlow; John P. M. Wood; Robert J. Casson
TAGS: eye, lasers, pharmacy benefits managers, rats, safety, spectral domain-optical coherence tomography, diagnostic imaging, retina, histology, lights, manufactured
Trans. Vis. Sci. Tech.. 2020; 9(4):22. doi: https://doi.org/10.1167/tvst.9.4.22

Includes: Supplemental Content

Articles February 2020

Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types

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Phuong T. Lam; Christian Gutierrez; Katia Del Rio-Tsonis; Michael L. Robinson
TAGS: ganglia, organoids, photoreceptors, retina
Trans. Vis. Sci. Tech.. 2020; 9(3):21. doi: https://doi.org/10.1167/tvst.9.3.21

Includes: Multimedia, Supplemental Content

Articles February 2020

Comparison of Capillary and Schirmer Strip Tear Fluid Sampling Methods Using SWATH-MS Proteomics Approach

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Janika Nättinen; Ulla Aapola; Antti Jylhä; Anu Vaajanen; Hannu Uusitalo
TAGS: blood capillaries, datasets, libraries, proteins, proteomics, sampling method
Trans. Vis. Sci. Tech.. 2020; 9(3):16. doi: https://doi.org/10.1167/tvst.9.3.16

Includes: Supplemental Content

Articles February 2020

Visualization of the Retina in Intact Eyes of Mice and Ferrets Using a Tissue Clearing Method

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Yunyan Ye; Tung Anh Dinh Duong; Kengo Saito; Yohei Shinmyo; Yoshie Ichikawa; Tomomi Higashide; Kyosuke Kagami; Hiroshi Fujiwara; Kazuhisa Sugiyama; Hiroshi Kawasaki
TAGS: clearing of tissue specimen, eye, ferrets, immunohistochemistry, mice, retina, hydrogen peroxide, melanins
Trans. Vis. Sci. Tech.. 2020; 9(3):1. doi: https://doi.org/10.1167/tvst.9.3.1

Articles February 2020

PTEN Inhibition Facilitates Diabetic Corneal Epithelial Regeneration by Reactivating Akt Signaling Pathway

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Jing Li; Xia Qi; Xiaochuan Wang; Weina Li; Ya Li; Qingjun Zhou
TAGS: cornea, diabetes mellitus, epithelium, pten gene, mice, akt signaling pathway
Trans. Vis. Sci. Tech.. 2020; 9(3):5. doi: https://doi.org/10.1167/tvst.9.3.5

Articles November 2019

Physicochemical Properties of Hyaluronic Acid–Based Lubricant Eye Drops

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Pasquale Aragona; Peter A. Simmons; Hongpeng Wang; Tao Wang
TAGS: hyaluronic acid, mass or substance concentration per volume, ocular lubricants, viscosity, sodium, osmolality
Trans. Vis. Sci. Tech.. 2019; 8(6):2. doi: https://doi.org/10.1167/tvst.8.6.2

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International Retinal Laser Society Guidelines For Subthreshold Laser Treatment

DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

Expression Profiles of Inflammatory Cytokines in the Aqueous Humor of Children after Congenital Cataract Extraction

Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

Software for Quantifying and Batch Processing Images of Brn3a and RBPMS Immunolabelled Retinal Ganglion Cells in Retinal Wholemounts

A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population

Quantification of Growth Factors and Fibronectin in Diverse Preparations of Platelet-Rich Plasma for the Treatment of Ocular Surface Disorders (E-PRP)

Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

Development of Contact Lens-Shaped Crosslinked Amniotic Membranes for Sutureless Fixation in the Treatment of Ocular Surface Diseases

Apigenin and Ethaverine Hydrochloride Enhance Retinal Vascular Barrier In Vitro and In Vivo

Comparison of Subthreshold 577 and 810 nm Micropulse Laser Effects on Heat-Shock Protein Activation Kinetics: Implications for Treatment Efficacy and Safety

Evaluating the Correlation between Alzheimer's Amyloid-β Peptides and Glaucoma in Human Aqueous Humor

Safety Profile of Slit-Lamp-Delivered Retinal Laser Photobiomodulation

Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types

Comparison of Capillary and Schirmer Strip Tear Fluid Sampling Methods Using SWATH-MS Proteomics Approach

Visualization of the Retina in Intact Eyes of Mice and Ferrets Using a Tissue Clearing Method

PTEN Inhibition Facilitates Diabetic Corneal Epithelial Regeneration by Reactivating Akt Signaling Pathway

Physicochemical Properties of Hyaluronic Acid–Based Lubricant Eye Drops

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